Page last updated: 2024-08-21

deoxyuridine and trimetrexate

deoxyuridine has been researched along with trimetrexate in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Goldman, ID; Rape, TJ; Seither, RL1
Goldman, ID; Mikulecky, DC; Rape, TJ; Seither, RL; Trent, DF1
Bertino, JR; McGuire, JJ; Narayanan, R; Rodenhuis, S1
Cassidy, C; Chou, TC; Fanucchi, MP; Fleisher, M; Lokos, G; Niedzwiecki, D; Vidal, P; Walsh, TD; Williams, L; Young, CW1
Branda, RF; Carney, JK; McCormack, JJ; Moore, AL; Perlmutter, CA1
Galivan, J; Nimec, Z; Rhee, M1
Besserer, JA; Boritzki, TJ; Elslager, EF; Fry, DW; Jackson, RC; Leopold, WR; Sloan, BJ1

Other Studies

8 other study(ies) available for deoxyuridine and trimetrexate

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Animals; Computer Simulation; Deoxyuridine; DNA; Enzyme Reactivators; Floxuridine; Folic Acid; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Mice; Purines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Time Factors; Trimetrexate; Tumor Cells, Cultured

1992
Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells.
    The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29

    Topics: Animals; Computer Simulation; Deoxyuridine; Floxuridine; Folic Acid; Folic Acid Antagonists; Formates; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimidines; Quinazolines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Trimetrexate

1989
Development of an assay system for the detection and classification of methotrexate resistance in fresh human leukemic cells.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Adolescent; Adult; Aged; Cell Line; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Female; Humans; Leukemia; Male; Methotrexate; Quinazolines; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tritium

1986
Phase I and clinical pharmacology study of trimetrexate administered weekly for three weeks.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Bone Marrow; Chromatography, High Pressure Liquid; Deoxyuridine; Drug Evaluation; Female; Hematopoietic Stem Cells; Humans; Kinetics; Lung Neoplasms; Mathematics; Middle Aged; Quinazolines; Thrombocytopenia; Trimetrexate

1987
Inhibition of lymphocyte nucleic acid metabolism and antibody production by trimetrexate.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: Antibody Formation; Deoxyuridine; DNA; Humans; Interphase; Lymphocytes; Methotrexate; Nucleic Acids; Quinazolines; Thymidine; Trimetrexate

1987
Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Liver Neoplasms, Experimental; Methotrexate; Pyrimethamine; Quinazolines; Rats; Thymidine; Thymidylate Synthase; Trimetrexate

1987
Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Mice, Inbred Strains; Quinazolines; Ribonucleotides; Thymidine; Trimetrexate

1984