Page last updated: 2024-08-21

deoxyuridine and methotrexate

deoxyuridine has been researched along with methotrexate in 148 studies

Research

Studies (148)

Timeframe	Studies, this research(%)	All Research%
pre-1990	137 (92.57)	18.7374
1990's	8 (5.41)	18.2507
2000's	2 (1.35)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (0.68)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Groth, DP; Kinkade, JM; Ross, DD	1
Roberts, D; Warmath, EV	1
Biermann, WA; Haurani, FI; Kardinal, CG	1
Bertino, JR; Cadman, EC; Cashmore, AR; Sawicki, WL; Skeel, RT	1
Fyfe, MJ; Hamrell, M; Laszlo, J; Sedwick, WD	1
Brown, OE; Frazer, T; Kutler, M; Laszlo, J; Sedwick, WD	1
Sauer, H; Schalhorn, A; Wilmanns, W	2
Kyburz, S; Schaer, JC; Schindler, R	1
Van Der Weyden, MB	1
Brown, OE; Frazer, TA; Fyfe, MJ; Kutler, M; Laszlo, J; Sedwick, WD	1
Hart, LI; Jackson, RC; Niethammer, D	1
Marquet, J; Zittoun, J; Zittoun, R	1
Bowen, D; Goldman, ID; White, JC	1
Kaufmann, M; Kubli, F; Reus, W; Volm, M; von Fournier, D	1
Fung, WP; Yang, KH; Zaharko, DS	1
Sauer, H; Wilmanns, W	1
Bender, RA; Nichols, AP; Warren, RD	1
Hummel, H; Mattern, J; Volm, M	1
Curt, GA; Kramer, RA; Parker, LM; Rosowsky, A; Tattersall, MH; Tobias, JS	1
Blakley, RL; Ho, YK; Hoffmann, CC; Thompson, JS	1
Hryniuk, WM	1
Hägerström, T; Humla, S; Nordenskjöld, B; Skoog, L	1
Bender, RA; Bleyer, WA; Drake, JC; Ziegler, JL	1
Håkansson, L	1
Greenberg, ML; Waxman, S	1
Dedrick, RL	1
McCullough, JL; Weinstein, GD	1
Bonney, RJ; Maley, F	1
Grem, JL	1
Bunni, M; Freisheim, JH; Galivan, J; Priest, DG; Rhee, M; Whiteley, JM	1
De Gialluly, E; Marquet, J; Pilorget, JJ; Tonetti, C; Zittoun, J	1
Alarcòn, GS; Baggott, JE; Everson, MP; Hardin, JM; Hine, RJ; Koopman, WJ; Krumdieck, CL; Morgan, SL	1
Gill, DS; Latham, J; Wickramasinghe, SN	1
Ghitis, J; Schreiber, C; Waxman, S	1
Goldman, ID; Rape, TJ; Seither, RL	1
Goldman, ID; Mikulecky, DC; Rape, TJ; Seither, RL; Trent, DF	1
Bertino, JR; McGuire, JJ; Narayanan, R; Rodenhuis, S	1
Branda, RF; Carney, JK; McCormack, JJ; Moore, AL; Perlmutter, CA	1
Galivan, J; Nimec, Z; Rhee, M	1
FitzGerald, GB; Ratliff, J; Wick, MM	1
Kalman, TI; Yalowich, JC	1
Salord, J; Schuber, F	1
Abels, J; Ermens, AA; Kroes, AC; Lindemans, J; Schoester, M; van Lom, K	1
Iseki, T; Iwasa, S; Kanazawa, S; Kondo, H; Okuda, K	1
Iwata, N; Maekawa, T; Omine, M; Yamauchi, H	2
Iwata, N; Karasawa, M; Katahira, H; Maekawa, T; Omine, M; Sugita, Y; Tokue, Y; Tsukamoto, N; Yamauchi, H; Yatabe, H	1
Hashimoto, K; Kinsky, SC; Loader, JE	1
Diddens, H; Niethammer, D; Teufel, T	1
Dickey, L; Goulian, M; Ingraham, HA	1
Allegra, CJ; Chabner, BA; Drake, JC; Fine, RL	1
Abels, J; Kroes, AC; Lindemans, J; Schoester, M	1
Chu, TM; Deguchi, T; Horoszewicz, JS; Lee, CL; Leong, SS	1
Iland, HJ; Laszlo, J; Sedwick, WD	1
Clarke, R; Kennedy, DG; Murphy, RF; Van den Berg, HW	1
Hashimoto, K; Kinsky, SC; Knight, MS; Loader, JE	1
Hirsiger, H; Schaer, JC; Schindler, R; Siegers, MP	1
Foley, GE; Lazarus, H	1
Grossowicz, N; Mandelbaum-Shavit, F	1
Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E	1
Fridland, A	1
Berry, CL; Germain, J; Looker, T	1
Harrap, KR; Tattersall, MH	1
DaCosta, M; Kamen, B; Rothenberg, SP	1
Hussa, RO; Pattillo, RA	1
Hutchison, DJ; Philips, FS; Sirotnak, FM; Sodergren, JE	1
Edlis, H; Herbert, V; Tisman, G	1
Donsbach, RC; Sirotnak, FM	1
Chabner, BA; Young, RC	1
Bertino, JR; Cashmore, AR; Sawicki, WL; Skeel, RT	1
Newbold, PC	1
Jasińska, JK; Steffen, JA; Swierkowska, KM	1
Auletta, AE; Davis, J; Gery, AM; Mead, JA; Mishra, L; Parmar, A	1
Hillcoat, BL; Kawai, M	1
Dedrick, RL; Drake, JC; Lutz, RJ; Peale, AL; Zaharko, DS	1
Goldman, ID	1
Fyfe, MJ; Goldman, ID	1
Crawford, EJ; Friedkin, M; Livingston, D	1
Borsa, J; Whitmore, GF	1
Wilmanns, W	1
Bertino, JR; Chabner, B; Levitt, M; McCullough, JL	1
Hofer, KG	2
Firkin, B; Rother, M; Van der Weyden, M	1
Green, R; Metz, J; Sive, J	1
Shapiro, WR	1
Frost, P; Goldfaden, G; Weinstein, GD	1
Nathanson, L	1
Hall, TC; Roberts, D	2
Hall, TC; Roberts, D; Rosenthal, D	1
Groth, DP; Horwitz, S; Vogler, WR	1
Bertino, JR; Hryniuk, WM	2
White, JE	1
Bertino, JR; Capizzi, RL; Cashmore, AR; Johns, DG; Nahas, A	1
Lampkin, BC; Mauer, AM; Nagao, T	1
Ernst, P; Killmann, SA	1
Bertino, JR; Capizzi, RL; Summers, WP	1
Weinstein, GD	1
Abboud, G; Bertino, JR; Fölsch, E; Gralla, E	1
Bertino, JR; Capizzi, R; Hryniuk, WM	1
Loehr, EV; Roberts, D	1
Bertino, JR; Fischer, GA; Hryniuk, WM	1
Himmelfarb, P; Roberts, D; Thayer, PS	1
Joseph, LB; Simon, GT; Singh, AD; Singh, SP; Von Essen, CF	1
Herbert, V; Kelly, A; Metz, J; Swett, VC; Waxman, S	1
Roberts, D; Wodinsky, I	1
Herbert, V; Metz, J; Waxman, S	1
Herbert, V; Waxman, S	1
Benz, C; Cadman, E; Heimer, R	1
Bowen, D; Gewirtz, DA; Goldman, D	1
Beaulieu, D; Matiaszuk, NV; Pottier, A; Rosenblatt, DS; Vuchich, MJ; Whitehead, VM	1
Rosenblatt, DS; Whitehead, VM	1
Perez, DJ; Slowiaczek, P; Tattersall, MH	1
Bailey, BD; Bowen, D; Guernsey, LA	1
Besserer, JA; Boritzki, TJ; Elslager, EF; Fry, DW; Jackson, RC; Leopold, WR; Sloan, BJ	1
Beck, WS; Pelliniemi, TT	1
Bowen, D; Fölsch, E; Guernsey, LA	1
Block, JB; Chlebowski, RT; Dietrich, MF; Isacoff, WH	1
Bover, L; Cabral, S; Leis, S; Mordoh, J; Nembrot, M	1
Calvert, AH; Jackman, AL; Jackson, RC	1
Perez, DJ; Tattersall, MH	1
Das, KC; Garewal, G; Mohanty, D	1
Brown, OE; Fyfe, MJ; Laszlo, J; Sedwick, WD	1
Chacón, RD; Filmus, J; Mordoh, J	1
Chu, BC; Howell, SB; Weisman, MH; Wigginton, SM	1
Greco, WR; Hakala, MT	1
Browman, GP; Calvert, AH; Harrap, KR; Hart, LI; Taylor, GA	1
Santi, DV	1
Sauer, H; Schalhorn, A	1
Brown, OE; Hamrell, M; Laszlo, J; Sedwick, WD	2
Chasin, LA; Landzberg, M; Urlaub, G	1
Clarke, R; Murphy, RF; Van den Berg, HW	1
Chu, BC; Howell, SB	1
Hida, K; Kano, Y; Kubota, T; Sakamoto, S; Sakuraya, K; Suda, K; Takaku, F	1
Laszlo, J; Sedwick, WD	1
Bleile, B; Goulian, M; Tseng, BY	1
Fernandes-Costa, F; Metz, J; Miller, H	1
Gimsing, P; Hippe, E	1
Arza, B; Barceló, MJ; Cadafalch, J; García-Die, F; Parellada, MM; Remacha, A	1
Fahrig, R; Steinkamp-Zucht, A	1
Bacherikov, VA; Chao, TC; Chen, CM; Chen, KT; Huang, YL; Lee, YJ; Li, WW; Lin, CF; Su, TL	1
Bi, J; Wang, L; Wang, Y	1

Reviews

7 review(s) available for deoxyuridine and methotrexate

Article	Year
Radiation sensitizers. Cancer, 1976, Volume: 37, Issue:4 Suppl Topics: Animals; Antineoplastic Agents; Bromodeoxycytidine; Bromodeoxyuridine; Carcinoma; Deoxyuridine; Dogs; Dose-Response Relationship, Radiation; Floxuridine; Humans; Hypoxia; Idoxuridine; Lung Neoplasms; Methotrexate; Metronidazole; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitroimidazoles; Radiation-Sensitizing Agents; Research; Sarcoma, Experimental; Skin	1976
Pharmacokinetic and pharmacodynamic considerations for chronic hemodialysis. Kidney international. Supplement, 1975, Issue:2 Topics: Animals; Antineoplastic Agents; Biological Transport; Chlorides; Deoxyuridine; Humans; Kinetics; Methotrexate; Models, Biological; Renal Dialysis	1975
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate	1992
Effects of amethopterin treatment on thymidylate synthesis in human leucocytes and bone marrow cells. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Adult; Binding Sites; Bone Marrow; Bone Marrow Cells; Chromatography, Thin Layer; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukocytes; Male; Methotrexate; Protein Binding; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymine Nucleotides; Tritium	1971
New approaches to chemotherapy with folate antagonists: use of leucovorin "rescue" and enzymic folate depletion. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Adult; Animals; Carboxypeptidases; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Deoxyuridine; Diet; Drug Combinations; Drug Synergism; Folic Acid Antagonists; Humans; Leucovorin; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mice; Rats; Tritium	1971
Some considerations in the experimental approach to distinguishing between membrane transport and intracellular disposition of antineoplastic agents, with specific reference to fluorodeoxyuridine, actinomycin D, and methotrexate. Cancer treatment reports, 1981, Volume: 65 Suppl 3 Topics: Animals; Antineoplastic Agents; Biological Transport; Biotransformation; Cell Membrane; Dactinomycin; Deoxyuridine; Floxuridine; Humans; Kinetics; Liver; Methotrexate; Polyglutamic Acid; Tritium	1981
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase. Journal of medicinal chemistry, 1980, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil	1980

Other Studies

141 other study(ies) available for deoxyuridine and methotrexate

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Effects of urinary proteins from certain leukemics upon macromolecular synthesis and enzyme levels in bone marrow cultures. The Journal of biological chemistry, 1975, Nov-25, Volume: 250, Issue:22 Topics: Adenine Phosphoribosyltransferase; Amidophosphoribosyltransferase; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Deoxyuridine; DNA; Female; Floxuridine; Humans; Leukemia; Male; Methotrexate; Mice; Mice, Inbred C57BL; Muramidase; Neoplasm Proteins; Proteinuria; RNA; Thymidine Kinase	1975
Methotrexate inhibition of CCRF-CEM cultures of human lymphoblasts. European journal of cancer, 1975, Volume: 11, Issue:11 Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Folic Acid Antagonists; Humans; Hypoxanthines; Leucovorin; Leukemia, Lymphoid; Methotrexate; Purines; Thymidine	1975
Thymidylate synthetase and dihydrofolic acid reductase in the stimulated human lymphocyte. Journal of cellular physiology, 1978, Volume: 95, Issue:1 Topics: Cells, Cultured; Deoxyuridine; Floxuridine; Humans; Lectins; Lymphocytes; Methotrexate; Methyltransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidylate Synthase	1978
Natural resistance to methotrexate in human acute nonlymphocytic leukemia. Cancer treatment reports, 1977, Volume: 61, Issue:4 Topics: Adult; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Female; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase	1977
Comparative studies of methotrexate and metoprine: metabolic toxicity and cell killing. Advances in enzyme regulation, 1978, Volume: 17 Topics: Antineoplastic Agents; Cell Line; Cell Survival; Deoxyuridine; DNA; Drug Therapy, Combination; Humans; Kinetics; Leukemia, Myeloid; Lymphocytes; Methotrexate; Pyrimethamine	1978
New dose-time relationships of folate antagonists to sustain inhibition of human lymphoblasts and leukemic cells in vitro. Cancer research, 1979, Volume: 39, Issue:9 Topics: Cell Line; Cell Survival; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Leucovorin; Leukemia; Methotrexate; Pyrimethamine; Time Factors	1979
The biochemistry of the citrovorum factor rescue effect in normal bone marrow cells after high-dose methotrexate. European journal of cancer, 1979, Volume: 15, Issue:10 Topics: Adult; Bone Marrow; Cells, Cultured; Deoxyuridine; Humans; Leucovorin; Lymphocytes; Male; Methotrexate; Middle Aged; Osteosarcoma; Thymidine; Thymidine Kinase	1979
Effects of methotrexate on thymidine triphosphate levels in Chinese hamster cell cultures. Biochemical pharmacology, 1979, Jun-15, Volume: 28, Issue:12 Topics: Animals; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Female; Methotrexate; Ovary; Thymine Nucleotides	1979
Deoxyuridine metabolism in human megaloblastic marrow cells. Scandinavian journal of haematology, 1979, Volume: 23, Issue:1 Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Thymidine; Thymidylate Synthase; Vitamin B 12; Vitamin B 12 Deficiency	1979
Deoxyuridine incorporation as a useful measure of methotrexate and metoprine uptake and metabolic effectiveness. Molecular pharmacology, 1979, Volume: 16, Issue:2 Topics: Deoxyuridine; Folic Acid Antagonists; Humans; Kinetics; Methotrexate; Pyrimethamine; Time Factors	1979
Reactivation of dihydrofolate reductase inhibted by methotrexate or aminopterin. Archives of biochemistry and biophysics, 1977, Volume: 182, Issue:2 Topics: Aminopterin; Animals; Cell Line; Computers; Deoxyuridine; Dialysis; Enzyme Activation; Folic Acid Antagonists; Kinetics; Leukemia L1210; Mathematics; Methotrexate; Protein Binding; Tetrahydrofolate Dehydrogenase	1977
Effect of folate and cobalamin compounds on the deoxyuridine suppression test in vitamin B12 and folate deficiency. Blood, 1978, Volume: 51, Issue:1 Topics: Deoxyuridine; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency	1978
A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro. Cancer research, 1978, Volume: 38, Issue:1 Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; In Vitro Techniques; Methotrexate; Mice; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine Monophosphate	1978
[Short-term incubation in vitro with precursors of nucleic acids on human primary tumors and metastases of carcinoma of the breast (author's transl)]. Strahlentherapie, 1978, Volume: 154, Issue:4 Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Deoxyuridine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Humans; Lymphatic Metastasis; Methotrexate; Thymidine; Uridine	1978
Relative biochemical aspects of low and high doses of methotrexate in mice. Cancer research, 1977, Volume: 37, Issue:6 Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Infusions, Parenteral; Intestine, Small; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Thymidine; Thymidine Monophosphate	1977
Cobalamin dependent methionine synthesis and methyl-folate-trap in human vitamin B12 deficiency. British journal of haematology, 1977, Volume: 36, Issue:2 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Folic Acid; Humans; Methotrexate; Methyltransferases; Tetrahydrofolates; Thymidine; Vitamin B 12 Deficiency	1977
The effect of vincristine on methotrexate uptake and inhibition of DNA synthesis by human lymphoblastoid cells. Cancer research, 1977, Volume: 37, Issue:9 Topics: Cell Line; Deoxyuridine; DNA; Drug Therapy, Combination; Humans; Leukemia; Lymphocytes; Methotrexate; Vincristine	1977
[Correlation between the effects of cytostatic agents on leukemia L 1210 in vivo and in the short term test in vitro (author's transl)]. Blut, 1977, Jul-20, Volume: 35, Issue:1 Topics: Animals; Cell Count; Culture Techniques; Deoxyuridine; Doxorubicin; Female; Leucine; Leukemia L1210; Methotrexate; Mice; Thymidine; Time Factors; Uridine; Vinblastine	1977
Inhibition of nucleic acid synthesis by the di-n-butyl ester of methotrexate. Biochemical pharmacology, 1976, Sep-01, Volume: 25, Issue:17 Topics: Cell Line; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Methotrexate; Thymidine; Time Factors	1976
Comparative effects of selected antifolates on transforming human lymphocytes and on established human lymphoblastic cell lines. Biochemical pharmacology, 1976, Sep-01, Volume: 25, Issue:17 Topics: Animals; Cattle; Cell Line; Deoxyuridine; Folic Acid Antagonists; Humans; In Vitro Techniques; Lectins; Liver; Lymphocyte Activation; Methotrexate; Mitosis; Stimulation, Chemical; Thymidine; Time Factors	1976
The mechanism of action of methotrexate in cultured L5178Y leukemia cells. Cancer research, 1975, Volume: 35, Issue:4 Topics: Animals; Cell Line; Cell Survival; Deoxyuridine; DNA, Neoplasm; Hypoxanthines; Kinetics; Leukemia, Lymphoid; Methotrexate; Mice; Models, Biological; Thymidine; Time Factors	1975
Effects of methotrexate on deoxyribonucleotide pools and nucleic acid synthesis in human osteosarcoma cells. European journal of cancer, 1976, Volume: 12, Issue:10 Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Breast Neoplasms; Cells, Cultured; Deoxyribonucleotides; Deoxyuridine; DNA; Female; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Osteosarcoma; RNA; Time Factors	1976
In vitro correlates of clinical response to methotrexate in actue leukaemia and Burkitt's lymphoma. British journal of cancer, 1976, Volume: 34, Issue:5 Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Burkitt Lymphoma; Cells, Cultured; Child; Child, Preschool; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Methotrexate	1976
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells. Arzneimittel-Forschung, 1975, Volume: 25, Issue:3 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine	1975
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia. European journal of cancer, 1976, Volume: 12, Issue:8 Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine	1976
Effects of methotrexate esters on normal and psoriatic skin. Archives of dermatology, 1975, Volume: 111, Issue:4 Topics: Chemical Phenomena; Chemistry; Chronic Disease; Deoxyuridine; Depression, Chemical; DNA; Humans; Lipids; Methotrexate; Psoriasis; Skin; Solubility; Thymidine	1975
Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver. Cancer research, 1975, Volume: 35, Issue:8 Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Liver; Liver Regeneration; Methotrexate; Methyltransferases; Protein Biosynthesis; Puromycin; Rats; Stimulation, Chemical; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase	1975
The effect of methotrexate on the folate coenzyme pools in human hepatoma cells in culture. Advances in experimental medicine and biology, 1991, Volume: 309A Topics: Carbon Radioisotopes; Carcinoma, Hepatocellular; Deoxyuridine; Folic Acid; Glycine; Humans; Kinetics; Liver Neoplasms; Methotrexate; Tritium; Tumor Cells, Cultured	1991
Comparative effect of 6S, 6R and 6RS leucovorin on methotrexate rescue and on modulation of 5-fluorouracil. British journal of cancer, 1991, Volume: 63, Issue:6 Topics: Analysis of Variance; Cell Line; Cell Survival; Deoxyuridine; DNA Replication; Fluorouracil; Humans; Leucovorin; Methotrexate; Stereoisomerism; Tumor Stem Cell Assay	1991
Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation. Rheumatology international, 1990, Volume: 10, Issue:4 Topics: Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Culture Media; Deoxyuridine; DNA; Female; Folic Acid; Humans; Lectins; Leukocytes, Mononuclear; Male; Methotrexate; Middle Aged; Phytohemagglutinins; Thymidine; Tritium	1990
Effects of phenytoin sodium on doubling time, deoxyuridine suppression, 3H-methotrexate uptake and 57Co-cyanocobalamin uptake in HL60 cells. Clinical and laboratory haematology, 1990, Volume: 12, Issue:1 Topics: Cell Division; Cell Survival; Cobalt Radioisotopes; Deoxyuridine; Folic Acid; Humans; Methotrexate; Phenytoin; Tritium; Tumor Cells, Cultured; Vitamin B 12	1990
Phosphate-induced phosphoribosylpyrophosphate elevations to assess deranged folate and purine nucleotide metabolism. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 186, Issue:1 Topics: Cell Line; Deoxyuridine; Erythrocytes; Folic Acid; Humans; Leucovorin; Leukemia, Myeloid, Acute; Male; Methotrexate; Pentosephosphates; Phosphates; Phosphoribosyl Pyrophosphate; Purines; Stimulation, Chemical	1987
Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell. Biochemical pharmacology, 1989, Mar-01, Volume: 38, Issue:5 Topics: Animals; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Formates; Leucovorin; Leukemia L1210; Methotrexate; Mice; Polyglutamic Acid; Tumor Cells, Cultured	1989
Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells. The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29 Topics: Animals; Computer Simulation; Deoxyuridine; Floxuridine; Folic Acid; Folic Acid Antagonists; Formates; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimidines; Quinazolines; Tetrahydrofolates; Thermodynamics; Thymidylate Synthase; Trimetrexate	1989
Development of an assay system for the detection and classification of methotrexate resistance in fresh human leukemic cells. Cancer research, 1986, Volume: 46, Issue:12 Pt 1 Topics: Adolescent; Adult; Aged; Cell Line; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Female; Humans; Leukemia; Male; Methotrexate; Quinazolines; Tetrahydrofolate Dehydrogenase; Trimetrexate; Tritium	1986
Inhibition of lymphocyte nucleic acid metabolism and antibody production by trimetrexate. Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10 Topics: Antibody Formation; Deoxyuridine; DNA; Humans; Interphase; Lymphocytes; Methotrexate; Nucleic Acids; Quinazolines; Thymidine; Trimetrexate	1987
Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine. Cancer research, 1987, Oct-15, Volume: 47, Issue:20 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Liver Neoplasms, Experimental; Methotrexate; Pyrimethamine; Quinazolines; Rats; Thymidine; Thymidylate Synthase; Trimetrexate	1987
Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine. Anti-cancer drug design, 1987, Volume: 1, Issue:4 Topics: Animals; Cytarabine; Daunorubicin; Deoxyuridine; DNA; Dopamine; Floxuridine; Hydroxyurea; Kinetics; Leukemia L1210; Methotrexate; Thymidylate Synthase	1987
Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro. Biochemical pharmacology, 1985, Jul-01, Volume: 34, Issue:13 Topics: Animals; Cells, Cultured; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Floxuridine; Leukemia L1210; Methotrexate; Methyltransferases; Mice; Thymidylate Synthase; Tritium	1985
In vitro drug delivery mediated by ecto-NAD+-glycohydrolase ligand-targeted liposomes. Biochimica et biophysica acta, 1988, Sep-16, Volume: 971, Issue:2 Topics: Ammonium Chloride; Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Division; Cell Line; Deoxyuridine; Drug Carriers; Fibroblasts; Humans; Kinetics; Liposomes; Methotrexate; Mice; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Sulfhydryl Compounds; Tumor Cells, Cultured	1988
Effect of cobalamin inactivation on folate metabolism of leukemic cells. Leukemia research, 1988, Volume: 12, Issue:11-12 Topics: Bone Marrow; Cell Line; Deoxyuridine; Female; Folic Acid; Humans; Leukemia; Male; Methotrexate; Nitrous Oxide; Tumor Cells, Cultured; Vitamin B 12	1988
Effect of methotrexate on the deoxyuridine suppression test: results with different cell preparations. American journal of hematology, 1988, Volume: 27, Issue:2 Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA; Formyltetrahydrofolates; Humans; Methotrexate; Microchemistry; Tetrahydrofolates; Thymidine	1988
[Folate status in vitamin B12-deficient megaloblastic bone marrow cells: enhanced sensitivity to methotrexate and increased rescue effects of folates]. Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1988, Volume: 51, Issue:3 Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Deoxyuridine; DNA; Female; Folic Acid; Humans; Male; Methotrexate; Vitamin B 12 Deficiency	1988
[Relative sensitivity of acute leukemia cells to methotrexate in vitro and the rescue effects of folates]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1987, Volume: 28, Issue:8 Topics: Deoxyuridine; Drug Screening Assays, Antitumor; Folic Acid; Humans; Leukemia, Myeloid, Acute; Methotrexate; Tumor Cells, Cultured	1987
Inhibition of cell proliferation by putative metabolites and non-degradable analogs of methotrexate-gamma-dimyristoylphosphatidylethanolamine. Biochimica et biophysica acta, 1987, Feb-14, Volume: 917, Issue:2 Topics: Cell Division; Cell Line; Deoxyuridine; Humans; Liposomes; Methotrexate; Phosphatidylethanolamines; T-Lymphocytes	1987
High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines. Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:2 Topics: Cell Line; Cell Survival; Deoxyuridine; DNA, Neoplasm; Humans; Leucovorin; Methotrexate; Osteosarcoma; Thymidine; Tumor Cells, Cultured	1987
DNA fragmentation and cytotoxicity from increased cellular deoxyuridylate. Biochemistry, 1986, Jun-03, Volume: 25, Issue:11 Topics: Animals; Cell Line; Cell Survival; Cricetinae; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Lung; Methotrexate; Phosphorus Radioisotopes; Radioisotope Dilution Technique	1986
The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis. The Journal of biological chemistry, 1986, May-15, Volume: 261, Issue:14 Topics: Breast Neoplasms; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Deoxyuridine; Female; Folic Acid; Formyltetrahydrofolates; Humans; Methotrexate; Purines; Time Factors	1986
Enhanced therapeutic effect of methotrexate in experimental rat leukemia after inactivation of cobalamin (vitamin B12) by nitrous oxide. Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:2 Topics: Animals; Blood Cell Count; Deoxyuridine; Drug Administration Schedule; Drug Synergism; Folic Acid; Leukemia, Experimental; Male; Methotrexate; Nitrous Oxide; Rats; Thymine Nucleotides; Vitamin B 12	1986
Effect of methotrexate-monoclonal anti-prostatic acid phosphatase antibody conjugate on human prostate tumor. Cancer research, 1986, Volume: 46, Issue:8 Topics: Acid Phosphatase; Animals; Antibodies, Monoclonal; Deoxyuridine; Folic Acid Antagonists; Humans; Immunoglobulin G; Male; Methotrexate; Mice; Mice, Nude; Prostate; Prostatic Neoplasms; Tritium	1986
Paradoxical effect of BW 301U, a lipophilic antifolate, on methotrexate-inhibitable deoxyuridine incorporation by human hematopoietic cells. Cancer research, 1985, Volume: 45, Issue:8 Topics: Antineoplastic Agents; Biological Transport; Bone Marrow; Deoxyuridine; Folic Acid Antagonists; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Pyrimidines; Thymidine; Tritium	1985
Oestrogen receptor status and the response of human breast cancer cell lines to a combination of methotrexate and 17-beta oestradiol. British journal of cancer, 1985, Volume: 51, Issue:3 Topics: Breast Neoplasms; Cell Division; Cell Line; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Estradiol; Female; Humans; Methotrexate; Receptors, Estradiol; Receptors, Estrogen	1985
Inhibition of cell proliferation and dihydrofolate reductase by liposomes containing methotrexate-dimyristoylphosphatidylethanolamine derivatives and by the glycerophosphorylethanolamine analogs. Biochimica et biophysica acta, 1985, Jun-11, Volume: 816, Issue:1 Topics: Ammonium Chloride; Animals; Biological Transport; Cell Division; Chemical Phenomena; Chemistry; Deoxyuridine; DNA; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Liposomes; Methotrexate; Mice; Phosphatidylethanolamines; Thiamine Pyrophosphate	1985
Determination of rates of DNA synthesis in cultured mammalian cell populations. The Journal of cell biology, 1974, Volume: 62, Issue:2 Topics: Animals; Autoradiography; Cell Division; Cell Line; Cells, Cultured; Deoxyuridine; DNA; DNA, Neoplasm; Kinetics; Mast-Cell Sarcoma; Methotrexate; Mice; Mitosis; Neoplasm Transplantation; Thymidine	1974
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents. Biochemical pharmacology, 1967, Volume: 16, Issue:4 Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine	1967
Effect of folinate on thymidine uptake by Pediococcus cerevisiae. Journal of bacteriology, 1968, Volume: 95, Issue:4 Topics: Aminopterin; Carbon Isotopes; Deoxyuridine; Floxuridine; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Pediococcus; Temperature; Thymidine; Thymine; Tritium; Uracil	1968
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis. British journal of haematology, 1973, Volume: 25, Issue:4 Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium	1973
Effect of methotrexate on deoxyribonucleotide pools and DNA synthesis in human lymphocytic cells. Cancer research, 1974, Volume: 34, Issue:8 Topics: Adenosine; Adenosine Triphosphate; Cell Line; Cells, Cultured; Chromatography; Cytosine Nucleotides; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Guanosine Triphosphate; Humans; Kinetics; Leukemia, Lymphoid; Methotrexate; RNA, Neoplasm; Thymine Nucleotides; Tritium	1974
The effect of methotrexate on DNA synthesis and its reversal by folinic acid. Journal of embryology and experimental morphology, 1972, Volume: 28, Issue:3 Topics: Animals; Animals, Newborn; Deoxyuridine; DNA; Folic Acid Antagonists; Histocytochemistry; Leucovorin; Liver; Methotrexate; Mice; Tritium	1972
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil. Cancer research, 1973, Volume: 33, Issue:12 Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium	1973
DNA synthesis in chronic myelogenous leukemia cells: comparison of results in cells containing folate binding factor to replicating cells without binder. Blood, 1972, Volume: 39, Issue:5 Topics: Anemia, Hypochromic; Binding Sites; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA; DNA Replication; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Myeloid; Leukocytes; Lymphoma, Large B-Cell, Diffuse; Methotrexate; RNA; Thymidine; Tritium; Tuberculosis, Lymph Node; Uridine	1972
Effects of methotrexate on established cell lines of human choriocarcinoma. European journal of cancer, 1972, Volume: 8, Issue:5 Topics: Cell Line; Choriocarcinoma; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Methotrexate; Neoplasm Proteins; Pregnancy; Thymidine	1972
Uptake of methotrexate, aminopterin, and methasquin and inhibition of dihydrofolate reductase and of DNA synthesis in mouse small intestine. Cancer research, 1973, Volume: 33, Issue:1 Topics: Aminopterin; Animals; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Folic Acid Antagonists; Injections, Intravenous; Intestinal Mucosa; Intestine, Small; Male; Methotrexate; Methylation; Mice; Quinazolines	1973
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions. Cancer chemotherapy reports, 1973, Volume: 57, Issue:1 Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Neoplasms; Penicillamine; Thymidine; Time Factors; Tritium	1973
Differential cell permeability and the basis for selective activity of methotrexate during therapy of the L1210 leukemia. Cancer research, 1973, Volume: 33, Issue:6 Topics: Animals; Cell Membrane Permeability; Deoxyuridine; DNA, Neoplasm; Injections, Intraperitoneal; Injections, Subcutaneous; Intestine, Small; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Peritoneum; Tetrahydrofolate Dehydrogenase; Transplantation, Homologous; Tritium	1973
Threshold methotrexate concentration for in vivo inhibition of DNA synthesis in normal and tumorous target tissues. The Journal of clinical investigation, 1973, Volume: 52, Issue:8 Topics: Animals; Ascites; Ascitic Fluid; Bone Marrow; Deoxyuridine; Depression, Chemical; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Duodenum; Intestinal Mucosa; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine Nucleotides; Tritium	1973
The basis for the disparate sensitivity of L1210 leukemia and Walker 256 carcinoma to a new triazine folate antagonist. Cancer research, 1973, Volume: 33, Issue:11 Topics: Animals; Antineoplastic Agents; Biological Transport; Carcinoma 256, Walker; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Methotrexate; Mice; Rats; Tetrahydrofolate Dehydrogenase; Triazines; Tritium	1973
Experimental studies on methotrexate and rat liver. The British journal of dermatology, 1973, Volume: 89, Issue:4 Topics: Animals; Deoxyuridine; DNA; Hepatectomy; Liver; Liver Regeneration; Methotrexate; Rats; Skin; Tetrahydrofolate Dehydrogenase; Thymidine Kinase; Thymidylate Synthase; Tritium	1973
5-Ethyl-2'-deoxyuridine: evidence for incorporation into DNA and evaluation of biological properties in lymphocyte cultures grown under conditions of amethopterine-imposed thymidine deficiency. Biochemical pharmacology, 1973, Jan-01, Volume: 22, Issue:1 Topics: Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cells, Cultured; Chromosome Aberrations; Culture Media; Deoxyuridine; DNA; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lymphocytes; Methotrexate; Mitosis; Thymidine; Time Factors	1973
The effect of folate and folate analogs upon dihydrofolate reductase and DNA synthesis in kidneys of normal mice. Life sciences, 1974, Apr-16, Volume: 14, Issue:8 Topics: Animals; Biological Transport; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Isotope Labeling; Kidney; Male; Methotrexate; Mice; Mice, Inbred Strains; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thymidine; Time Factors; Tritium; Ultracentrifugation; Ultrafiltration; Xanthopterin	1974
Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo. Cancer research, 1974, Volume: 34, Issue:7 Topics: Animals; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Folic Acid; Leukemia L1210; Methotrexate; Methyltransferases; Mice; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Tritium	1974
Relative toxicity of methotrexate in several tissues of mice bearing Lewis lung carcinoma. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 189, Issue:3 Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Membrane; Cell Membrane Permeability; Deoxyuridine; DNA, Neoplasm; Femur; Intestine, Small; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Tetrahydrofolate Dehydrogenase; Time Factors; Transplantation, Homologous; Tritium	1974
The mechanism of action of methotrexate. I. Interaction with a low-affinity intracellular site required for maximum inhibition of deoxyribonucleic acid synthesis in L-cell mouse fibroblasts. Molecular pharmacology, 1974, Volume: 10, Issue:2 Topics: Animals; Binding Sites; Carbon Radioisotopes; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA; Drug Synergism; Fibroblasts; Inulin; Kinetics; L Cells; Methotrexate; Mice; Temperature; Tetrahydrofolates; Tritium; Vincristine; Water	1974
The mechanism of action of methotrexate. II. Augmentation by vincristine of inhibition of deoxyribonucleic aic synthesis by methotrexate in Ehrlich ascites tumor cells. Molecular pharmacology, 1974, Volume: 10, Issue:2 Topics: Animals; Binding Sites; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Drug Synergism; Methotrexate; Mice; Mice, Inbred Strains; Time Factors; Tritium; Vincristine	1974
Studies with tetrahydrohomofolate and thymidylate synthetase from amethopterin-resistant mouse leukemia cells. Biochemistry, 1968, Volume: 7, Issue:8 Topics: Animals; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Deoxyuridine; Drug Stability; Escherichia coli; Folic Acid; Leukemia L1210; Ligases; Methotrexate; Mice; Nucleotides; Spleen; Splenic Neoplasms; Tetrahydrofolate Dehydrogenase	1968
Studies relating to the mode of action of methotrexate. 3. Inhibition of thymidylate synthetase in tissue culture cells and in cell-free systems. Molecular pharmacology, 1969, Volume: 5, Issue:4 Topics: Animals; Carcinoma, Ehrlich Tumor; Cell-Free System; Chromatography, Ion Exchange; Cricetinae; Culture Techniques; Deoxyuridine; DNA; Embryo, Mammalian; Escherichia coli; Folic Acid; Histocytochemistry; Kinetics; L Cells; Leucovorin; Methotrexate; Mice; Nucleotides; RNA; Thymidine; Transferases; Tritium	1969
In vivo effects of methotrexate. Inhibition of DNA synthesis and cell death in sensitive and resistant L1210 ascites populations. Chemotherapy, 1972, Volume: 17, Issue:1 Topics: Animals; Cell Count; Cell Survival; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA Replication; DNA, Neoplasm; Drug Resistance; Female; Injections, Intraperitoneal; Iodine Isotopes; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Time Factors	1972
Megaloblastic maturation masked by iron deficiency: a biochemical basis. British journal of haematology, 1972, Volume: 22, Issue:3 Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deferoxamine; Deoxyuridine; DNA; Folic Acid Deficiency; Humans; Iron; Methotrexate; Thymidine; Tritium; Vitamin B 12 Deficiency	1972
Effect of trimethoprim on folate-dependent DNA synthesis in human bone marrow. Journal of clinical pathology, 1972, Volume: 25, Issue:3 Topics: Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Pyrimidines; Thymidine; Trimethoprim; Tritium	1972
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors. Cancer research, 1972, Volume: 32, Issue:10 Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Isotopes; Carmustine; Cyclohexanes; Cytarabine; Deoxyuridine; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Ependymoma; Glioma; Lymph Nodes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Thymidine; Tritium	1972
Methotrexate. Mechanism of action on DNA synthesis in psoriasis. Archives of dermatology, 1971, Volume: 104, Issue:3 Topics: Autoradiography; Biopsy; Deoxyuridine; Depression, Chemical; DNA Replication; Humans; Injections, Intradermal; Injections, Intramuscular; Methotrexate; Psoriasis; Skin; Tritium	1971
In vivo prediction of drug sensitivity with cancer-seeking isotopes. National Cancer Institute monograph, 1971, Volume: 34 Topics: Amides; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Deoxyuridine; Diethylstilbestrol; Female; Fluorouracil; Fluoxymesterone; Humans; Imidazoles; Iodine Radioisotopes; Methotrexate; Neoplasms; Nitrosourea Compounds; Phosphates; Rats; Serum Albumin, Radio-Iodinated; Sodium Isotopes; Triazenes; Vincristine	1971
Dihydrofolate reductase activity and deoxynucleoside incorporation into DNA of human leukocytes. Relation to methotrexate administration. Cancer, 1967, Volume: 20, Issue:5 Topics: Adolescent; Adult; Child; Child, Preschool; Deoxyuridine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Nucleosides; Tetrahydrofolate Dehydrogenase; Thymidine	1967
Enzyme activities and deoxynucleoside utilization of leukemic leukocytes in relation to drug therapy and resistance. Cancer research, 1969, Volume: 29, Issue:1 Topics: Chronic Disease; Cyclophosphamide; Deoxyuridine; DNA; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytes; Ligases; Mercaptopurine; Methotrexate; Nucleosides; Nucleotides; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine Kinase	1969
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia. Cancer research, 1969, Volume: 29, Issue:3 Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase	1969
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism. Cancer research, 1969, Volume: 29, Issue:7 Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines	1969
Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates. The Journal of clinical investigation, 1969, Volume: 48, Issue:11 Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium	1969
Methotrexate inhibition of deoxyuridine incorporation in the skin of three day old rats. The Journal of investigative dermatology, 1971, Volume: 56, Issue:4 Topics: Animals; Deoxyuridine; Depression, Chemical; DNA; Folic Acid Antagonists; Methotrexate; Rats; Skin; Thymidine; Tritium	1971
Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells. Biochemical pharmacology, 1970, Volume: 19, Issue:4 Topics: Adult; Aged; Animals; Biological Transport; Cell Line; Chemical Precipitation; Chromatography; Chromatography, Gel; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Hydroxyapatites; Leukemia L1210; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Quaternary Ammonium Compounds; Quinazolines; Spectrophotometry; Sulfates; Tetrahydrofolate Dehydrogenase; Tritium; Ultraviolet Rays	1970
Synchronization and recruitment in acute leukemia. The Journal of clinical investigation, 1971, Volume: 50, Issue:10 Topics: Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Culture Techniques; Cyclophosphamide; Cytarabine; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine	1971
Perturbation of generation cycle of human leukemic myeloblasts in vivo by methotrexate. Blood, 1971, Volume: 38, Issue:6 Topics: Aged; Autoradiography; Bone Marrow Examination; Deoxyuridine; DNA; Erythrocytes; Female; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Mitosis; Spectrophotometry; Thymidine; Tritium; Vincristine	1971
L-asparaginase induced alteration of amethopterin (methotrexate) activity in mouse leukemia L5178Y. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Asparaginase; Asparagine; Cell Survival; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Female; Leukemia, Experimental; Methotrexate; Mice; Mice, Inbred Strains; Time Factors; Tritium	1971
Growth rate and cell kill. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Humans; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Thymidine; Time Factors; Tritium; Uridine	1971
Biochemical and pathophysiological rationale for amethopterin in psoriasis. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Administration, Oral; Autoradiography; Deoxyuridine; Epithelium; Germ Cells; Humans; Injections, Intramuscular; Methotrexate; Mitosis; Psoriasis; Skin; Thymidine; Time Factors; Tritium	1971
Studies with a 2,4-diamino-5-chloro-quinazoline antifolate: in vitro and invivo correlates in normal and lymphosarcoma dogs. Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186 Topics: Animals; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; DNA, Neoplasm; Dogs; Folic Acid Antagonists; Hydrogen-Ion Concentration; Injections, Intravenous; Leukemia L1210; Lymphoma, Non-Hodgkin; Methotrexate; Quinazolines; Thymine Nucleotides; Time Factors; Tritium	1971
Prediction of methotrexate responsiveness of tumors in man. National Cancer Institute monograph, 1971, Volume: 34 Topics: Deoxyuridine; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prognosis; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium	1971
Elevation of thymidylate synthetase activity in CCRF-CEM cells. Cancer research, 1971, Volume: 31, Issue:9 Topics: Cell Line; Cells, Cultured; Child; Deoxyuridine; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Methotrexate; Methyltransferases; Thymidine; Uracil Nucleotides	1971
Tumor cell death in vivo after administration of chemotherapeutic agents. Cancer chemotherapy reports, 1969, Volume: 53, Issue:5 Topics: Animals; Antineoplastic Agents; Deoxyuridine; Iodine Isotopes; Leukemia L1210; Methotrexate; Mice	1969
S-phase cells of rapidly growing and resting populations. Differences in response to methotrexate. Molecular pharmacology, 1969, Volume: 5, Issue:6 Topics: Animals; Cell Line; Clone Cells; Culture Techniques; Deoxyuridine; DNA; Folic Acid Antagonists; Kinetics; Leukemia, Experimental; Methotrexate; Mice; Thymidine; Time Factors; Tritium	1969
Effects of perfusion with amethopterin on L1210 leukemia cells in spin filter culture. Cancer research, 1970, Volume: 30, Issue:6 Topics: Agar; Animals; Binding Sites; Cell Count; Cell Division; Centrifugation; Clone Cells; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Leukemia L1210; Methods; Methotrexate; Methylation; Mice; Perfusion; Tetrahydrofolate Dehydrogenase; Time Factors; Transferases; Tritium; Uracil Nucleotides	1970
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results. The American journal of roentgenology, radium therapy, and nuclear medicine, 1968, Volume: 102, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage	1968
Deranged DNA synthesis by bone marrow from vitamin B-12-deficient humans. British journal of haematology, 1968, Volume: 14, Issue:6 Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Female; Folic Acid; Folic Acid Deficiency; Humans; In Vitro Techniques; Methionine; Methotrexate; Thymine; Tritium; Uridine; Vitamin B 12; Vitamin B 12 Deficiency	1968
On the poor correlation between the inhibition by methotrexate of dihydrofolate reductase and of deoxynucleoside incorporation into DNA. Cancer research, 1968, Volume: 28, Issue:10 Topics: Animals; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Neoplasm Transplantation; Nucleosides; Nucleotides; Thymidine	1968
Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine. The Journal of clinical investigation, 1969, Volume: 48, Issue:2 Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficiency; Homocysteine; Humans; In Vitro Techniques; Methionine; Methotrexate; Thymidine; Transferases; Tritium; Vitamin B 12 Deficiency	1969
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow. The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24 Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuridine; DNA; Erythrocytes; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Nucleotides; Oxidation-Reduction; Pyrimethamine; Thymidine; Tritium	1969
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells. The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4 Topics: Animals; Biological Transport; Deoxyuridine; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; RNA, Neoplasm	1981
Differential effects of folinic acid and glycine, adenosine, and thymidine as rescue agents in methotrexate-treated human cells in relation to the accumulation of methotrexate polyglutamates. Molecular pharmacology, 1982, Volume: 21, Issue:3 Topics: Adenosine; Deoxyuridine; DNA; Fibroblasts; Glycine; Humans; Leucovorin; Methotrexate; Polyglutamic Acid; Thymidine; Time Factors	1982
Methotrexate polyglutamates in cultured human cells. Advances in experimental medicine and biology, 1983, Volume: 163 Topics: Adenosine; Cells, Cultured; Deoxyuridine; DNA Replication; Fibroblasts; Glycine; Humans; Methotrexate; Peptides; Polyglutamic Acid; Protein Binding; Tetrahydrofolate Dehydrogenase; Thymidine	1983
Deoxyuridine metabolism in cultured human lymphoblasts treated with methotrexate. Cancer research, 1984, Volume: 44, Issue:2 Topics: Cell Line; Deoxyuridine; DNA; Humans; Lymphocytes; Methotrexate; Pentosyltransferases; RNA; Uridine Phosphorylase	1984
Rate-limiting steps in the interactions of fluoropyrimidines and methotrexate. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:5 Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Mice; Neoplasm Proteins; RNA, Neoplasm; Thymidine Monophosphate	1984
Biochemical pharmacology of the lipophilic antifolate, trimetrexate. Advances in enzyme regulation, 1984, Volume: 22 Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Mice, Inbred Strains; Quinazolines; Ribonucleotides; Thymidine; Trimetrexate	1984
Biochemical mechanisms in the Killmann experiment: critique of the deoxyuridine suppression test. The Journal of clinical investigation, 1980, Volume: 65, Issue:2 Topics: Deoxyribonucleosides; Deoxyuridine; DNA; Floxuridine; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Thymidine; Thymidine Kinase; Thymine Nucleotides	1980
fluoropyrimidine-induced antagonism to free and tightly bound methotrexate: suppression of [14C] formate incorporation into RNA and protein. European journal of cancer, 1980, Volume: 16, Issue:7 Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Floxuridine; Formates; Methotrexate; Mice; Neoplasm Proteins; RNA, Neoplasm	1980
Abnormal deoxyuridine suppression as a rapid predictor for antimetabolite chemosensitivity: correlation with in vitro tests of growth inhibition. Cancer treatment reports, 1984, Volume: 68, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyuridine; DNA; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Leukemia L1210; Methotrexate; Mice; Ovarian Neoplasms; Tumor Stem Cell Assay	1984
Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:10 Topics: Animals; Biological Transport; Deoxycytidine; Deoxyuridine; Dipyridamole; DNA Replication; Drug Antagonism; Kinetics; Methotrexate; Mice; Sarcoma 180; Thymidine; Thymine Nucleotides	1984
Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells. Biochemical pharmacology, 1983, Dec-15, Volume: 32, Issue:24 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Line; Deoxyribonucleotides; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Lymphocytes; Methotrexate; Methyltransferases; Quinazolines; Ribonucleotides; Thymidylate Synthase	1983
Assessment of antimetabolite cytotoxicity: a comparison of clonogenic assays and tritiated deoxyuridine incorporation. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:3 Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leukemia L1210; Melanoma; Methotrexate; Mice; Tritium	1983
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture. Acta haematologica, 1980, Volume: 64, Issue:3 Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; Folic Acid Deficiency; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Middle Aged; Thymidine; Vitamin B 12 Deficiency	1980
Human plasma and amino acids as moderators of uptake and metabolic consequences of antifolates in WIL-2 and human leukemia cells. Journal of the National Cancer Institute, 1981, Volume: 66, Issue:3 Topics: Amino Acids; Blood; Cell Line; Culture Media; Deoxyuridine; Folic Acid Antagonists; Glutamine; Humans; Kinetics; Leukemia; Lymphocytes; Methotrexate; Pyrimethamine	1981
Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate. Cancer research, 1981, Volume: 41, Issue:9 Pt 1 Topics: Cell Separation; Cells, Cultured; Deoxyuridine; DNA; Drug Resistance; Humans; Hypoxanthines; Lung Neoplasms; Methotrexate; Osteosarcoma; Stimulation, Chemical; Thymidine	1981
Methotrexate pharmacokinetics after intraarticular injection in patients with rheumatoid arthritis. Arthritis and rheumatism, 1980, Volume: 23, Issue:1 Topics: Arthritis, Rheumatoid; Bone Marrow; Deoxyuridine; Humans; Injections, Intra-Articular; Kinetics; Leucovorin; Methotrexate; Synovial Fluid	1980
Biochemical control of high-dose methotrexate/Leucovorin rescue therapy. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 74 Topics: Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Humans; Leucovorin; Methotrexate; Neoplasms; Thymidine; Thymidine Kinase	1980
Biochemical pharmacology of lipophilic diaminopyrimidine antifolates in mouse and human cells in vitro. Molecular pharmacology, 1980, Volume: 18, Issue:3 Topics: Animals; Cells, Cultured; Deoxyuridine; Folic Acid Antagonists; HeLa Cells; Humans; Kinetics; Leucovorin; Methotrexate; Mice; Pyrimidines; Solubility; Tetrahydrofolate Dehydrogenase	1980
The intracellular mechanism of action of metoprine (DDMP). European journal of cancer, 1980, Volume: 16, Issue:12 Topics: Animals; Cell Survival; Cells, Cultured; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimethamine; Pyrimidines; Thymidine	1980
[Radiational basis and practice of the citrovorum factor (Leucovorin) protection after high-dose methotrexate therapy. High-dose methotrexate/leucovorin]. Onkologie, 1980, Volume: 3, Issue:2 Topics: Bone Marrow; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Humans; Leucovorin; Lymphocytes; Methotrexate; Thymidine	1980
Characteristic abnormality of deoxyribonucleoside triphosphate metabolism in megaloblastic anemia. Blood, 1982, Volume: 60, Issue:4 Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyribonucleosides; Deoxyuridine; Humans; Methotrexate; Thymidine; Thymine Nucleotides	1982
Metabolic inhibition by a new antifolate, 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methyl-pyrido[2,3-d]pyrimidine (BW3O1U), an effective inhibitor of human lymphoid and dihydrofolate reductase-overproducing mouse cell lines. Molecular pharmacology, 1982, Volume: 22, Issue:3 Topics: Animals; Antimetabolites; Cell Line; Deoxyuridine; Folic Acid Antagonists; Kinetics; Lymphoid Tissue; Methotrexate; Mice; Phosphorus Radioisotopes; Pyrimidines; Tetrahydrofolate Dehydrogenase	1982
Selective killing of methotrexate-resistant cells carrying amplified dihydrofolate reductase genes. Cancer research, 1981, Volume: 41, Issue:5 Topics: Animals; Cricetinae; Cricetulus; Deoxyuridine; Drug Resistance; Female; Gene Amplification; Genes; Hybrid Cells; Karyotyping; Methotrexate; Ovary; Tetrahydrofolate Dehydrogenase; Tritium	1981
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12 Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Methotrexate; Thymidine	1981
Differential toxicity of carrier-bound methotrexate toward human lymphocytes, marrow and tumor cells. Biochemical pharmacology, 1981, Sep-15, Volume: 30, Issue:18 Topics: Astrocytoma; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chloroquine; Deoxyuridine; Humans; In Vitro Techniques; Lymphocytes; Methotrexate; Neoplasms, Experimental	1981
Effect of nitrous oxide on human bone marrow cells and its synergistic effect with methionine and methotrexate on functional folate deficiency. Cancer research, 1981, Volume: 41, Issue:11 Pt 1 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bone Marrow; Deoxyuridine; DNA; Drug Synergism; Folic Acid Antagonists; Humans; Methionine; Methotrexate; Methyltransferases; Neoplasms; Nitrous Oxide; Pteroylpolyglutamic Acids; Time Factors	1981
Toxicity of methotrexate and metoprine in a dihydrofolate reductase gene-amplified mouse cell line. Molecular pharmacology, 1981, Volume: 20, Issue:3 Topics: Cell Line; Clone Cells; Deoxyuridine; Folic Acid Antagonists; Kinetics; Methotrexate; Phosphorus Radioisotopes; Pyrimethamine; Tetrahydrofolate Dehydrogenase	1981
An antifolate-induced lesion in newly synthesized DNA. Advances in enzyme regulation, 1980, Volume: 19 Topics: Cell Line; Cell Survival; Deoxyuridine; DNA; Folic Acid Antagonists; Humans; Methotrexate; Molecular Weight; Pyrimethamine; Thymidine	1980
The effect of methotrexate on levels of dUTP in animal cells. The Journal of biological chemistry, 1980, Nov-25, Volume: 255, Issue:22 Topics: Cells, Cultured; Deoxyribonucleotides; Deoxyuracil Nucleotides; Deoxyuridine; Humans; Lymphocytes; Methotrexate; Thymine Nucleotides	1980
Synthesis of DNA as shown by the deoxyuridine suppression test is normal in the vitamin B12-deficient fruit bat (Rosettus Aegyptiacus). The British journal of nutrition, 1980, Volume: 44, Issue:3 Topics: Animals; Bone Marrow; Cells, Cultured; Chiroptera; Deoxyuridine; DNA; Folic Acid; Lymphocytes; Methotrexate; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency	1980
Cobalamin-dependent metabolism in chronic myelogenous leukemia determined by deoxyuridine suppression test and the formiminoglutamic acid and methylmalonate excretion in urine. American journal of hematology, 1995, Volume: 49, Issue:2 Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Female; Formiminoglutamic Acid; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Malonates; Methotrexate; Middle Aged; Tetrahydrofolates; Thymidine; Tritium; Vitamin B 12	1995
The deoxyuridine suppression test in HIV-1 positive patients: the role of azydothymidine (AZT). European journal of haematology, 1996, Volume: 56, Issue:4 Topics: Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; Folic Acid; HIV Infections; HIV-1; Humans; Intestinal Absorption; Methotrexate; Vitamin B 12; Vitamin B 12 Deficiency; Zidovudine	1996
Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters. Mutation research, 1996, Sep-23, Volume: 356, Issue:2 Topics: Acetamides; Acetone; Anthracenes; Carcinogens; Cell Line, Transformed; Coumarins; Deoxyuridine; Dimethylformamide; Diterpenes; DNA, Viral; Mercaptopurine; Methotrexate; Mutagens; Nitroquinolines; Nucleic Acid Hybridization; Simian virus 40; Terpenes; Testosterone; Tetradecanoylphorbol Acetate; Thioacetamide; Virus Replication	1996
Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies. Bioorganic & medicinal chemistry, 2003, Jan-02, Volume: 11, Issue:1 Topics: Antineoplastic Agents; Cell Survival; Deoxyuridine; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Humans; Leucovorin; Methotrexate; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tritium; Tumor Cells, Cultured	2003
In silico development and experimental validation of a novel 7-gene signature based on PI3K pathway-related genes in bladder cancer. Functional & integrative genomics, 2022, Volume: 22, Issue:5 Topics: Cisplatin; Deoxyuridine; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin G; Methotrexate; Mitomycin; Paclitaxel; Phosphatidylinositol 3-Kinases; Tumor Microenvironment; Urinary Bladder Neoplasms; Vinblastine; von Willebrand Factor	2022