Page last updated: 2024-08-21

deoxyuridine and fluorouracil

deoxyuridine has been researched along with fluorouracil in 109 studies

Research

Studies (109)

Timeframe	Studies, this research(%)	All Research%
pre-1990	76 (69.72)	18.7374
1990's	13 (11.93)	18.2507
2000's	8 (7.34)	29.6817
2010's	8 (7.34)	24.3611
2020's	4 (3.67)	2.80

Authors

Authors	Studies
Chen, MS; Prusoff, WH; Schinazi, RF	1
Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Grunden, EE; Jato, JG; Johnson, BM; Lake, LM	1
Pfefferkorn, ER; Pfefferkorn, LC	1
Bowen, D; Diasio, RB; Goldman, ID	1
Hopkins, HA; Kovacs, CJ; Looney, WB; Simon, RM	1
Hopkins, HA; Wakefield, JA	1
Hopkins, HA; Kovacs, CJ; Looney, WB; Wakefield, JA	1
Crumley, J; Wilkinson, DS	1
Fernandes, DJ; Klubes, P; Mandel, HG	1
Bowen, D; Goldman, ID; White, JC	1
Cerna, I; Connelly, K; Klubes, P; Mandel, HG	1
Cerna, I; Connelly, K; Geelhoed, GW; Klubes, P; Mandel, HG	1
Håkansson, L	1
Horwitz, JP; Kessel, D; Maher, VM; McCormick, JJ; Otto, JR; Philips, KD; Zemlicka, J	1
Cohen, AM	1
Chabner, BA; Myers, CE; Young, RC	1
Grem, JL	1
Braakhuis, BJ; Peters, GJ; Stringer, I; Visser, GW	1
Cravo, ML; Mason, JB; Rosenberg, IH; Selhub, J	1
De Gialluly, E; Marquet, J; Pilorget, JJ; Tonetti, C; Zittoun, J	1
McTiernan, RG; Sherertz, EF; Sloan, KB	1
Allegra, CJ; Fischer, PH; Grem, JL; Miller, EM; Mulcahy, RT	1
Kusumoto, H; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K	1
Farquhar, D; Freed, JJ; Hampton, A	1
Alison, DL; Calvert, AH; Harrap, KR; Jackman, AL	1
Fischer, PH; Grem, JL	1
Abels, J; Ermens, AA; Lindemans, J	1
Foley, GE; Lazarus, H	1
Bruns, R; Hall, TC; Kessel, D	1
Beck, CF; Ingraham, JL; Neuhard, J; Thomassen, E	1
Jato, J; Windheuser, JJ	2
Beck, A; Tan, YL	1
Chabner, BA; Johns, DG; Myers, CE; Young, RC	1
Gauri, KK; Kohlhage, H	1
Aaronson, SA	1
Erbe, J; Plagemann, PG	1
Lychev, VA	1
Harrap, KR; Tattersall, MH	1
Friedkin, M	1
Belousova, AK; Meĭren, DV	1
Edlis, H; Herbert, V; Tisman, G	1
Rizki, RM; Rizki, TM	1
Nathanson, L	1
Groth, DP; Horwitz, S; Vogler, WR	1
Bardos, TJ; Burgess, GH; Klein, E; Schwartz, SH	1
Eaglstein, WH; Frost, P; Weinstein, GD	1
Joseph, LB; Simon, GT; Singh, AD; Singh, SP; Von Essen, CF	1
Herbert, V; Waxman, S	1
Burk, D; Woods, MW	1
Gauri, KK; Malorny, G; Schiff, W	1
Benz, C; Cadman, E; Heimer, R	1
Evans, RM; Hakala, MT; Laskin, JD	2
Cerna, I; Klubes, P; Meldon, MA	1
Cadman, E; Grant, S	1
Bailey, BD; Bowen, D; Guernsey, LA	1
Jeney, A; Kopper, L; Lapis, K; Magyarosy, E; Otvös, L; Szabolcs, A	1
Fujii, S; Shirasaka, T	1
Cook, AF; Holman, MJ; Kramer, MJ	1
Block, JB; Chlebowski, RT; Dietrich, MF; Isacoff, WH	1
Perez, DJ; Tattersall, MH	1
Langen, P; Liermann, B; Matthes, E	1
Mattern, J; Volm, M; Wayss, K; Weber, N	1
Chikaraishi, Y; Tamemasa, O; Tezuka, M	1
Cerna, I; Klubes, P	1
Bruckner, H; Waxman, S	1
Santi, DV	1
Wickramasinghe, SN	1
Tamemasa, O; Tezuka, M	2
Clarke, R; Murphy, RF; Van den Berg, HW	1
Baptiste, N; Megati, S; Otter, BA; Schwartz, EL; Wadler, S	1
Beaumatin, J; Cathignol, D; Chapelon, JY; Luccioni, C; Pansu, D; Ponchon, T; Prat, F; Sibille, A	1
Braakhuis, BJ; Noordhuis, P; Peters, GJ; Smid, K; van der Wilt, CL; Visser, GW; Wedzinga, R	1
Gallinari, P; Jiricny, J; Kawate, T; Schärer, OD; Verdine, GL	1
Benkö, I; Jeney, A; Kovács, P; Kralovánszky, J; Megyeri, A	1
Erdélyi-Tóth, V; Jeney, A; Katona, C; Kovács, P; Kralovánszky, J; Noordhuis, P; Otvös, L; Pandi, E; Peters, GJ; Van der Wilt, CL	1
Fischel, JL; Jeney, A; Katona, C; Kralovánszky, J; Milano, G; Pandi, E; Tímár, F	1
Calvert, AH; Cunningham, D; Farrugia, DC; Ford, HE; Hill, ME; Jackman, AL; Judson, IR; Mitchell, F; Rees, C	1
BOLAFFI, JL; CHEONG, L; EIDINOFF, ML; KNOLL, JE; RICH, MA	1
BURCHENAL, JH; CLARKSON, B; GLATSTEIN, N; MILLER, E; SULLIVAN, RD; YOUNG, CW	1
BURCHENAL, JH; ELLISON, RR; ESCHER, G; KARNOFSKY, DA; KAUFMAN, R; LEVICK, SN; LI, MC; MILLER, E; SULLIVAN, RD; WOLDOW, I; YOUNG, CW	1
ANSFIELD, FJ; CURRERI, AR	1
NICHOL, CA; WHITE, PJ	1
ANSFIELD, FJ	1
BOND, SB; KRISS, JP	1
HAHN, RG; MOERTEL, CG; REITEMEIER, RJ	1
CURRERI, AR; JOHNSON, RO; WOLBERG, WH	1
Hatta, H; Nishimoto, S; Shibamoto, Y; Tachi, Y; Tanabe, K	1
Banken, L; Bellibas, SE; Brivet, B; Bush, ED; Chamorey, E; Kircher, C; Milano, G; Nave, S; Patel, I; Renée, N	1
Bocsi, J; Budai, B; Katona, C; Kralovánszky, J; Oláh, J; Otvös, L; Timár, F	1
Clarke, SJ; Li, KM; Rivory, LP	1
Clarke, SJ; Hoskins, J; Li, KM; Rivory, LP; Sharma, R	1
Engelbrecher, A; Häuser, R; Titz, B; Uetz, P	1
Ackland, SP; de Bock, CE; Garg, MB; Lincz, LF; Sakoff, JA; Scorgie, FE; Scott, N	1
Fairlamb, AH; Ong, HB; Patterson, S; Sienkiewicz, N; Wyllie, S	1
Gero, AM; Lutze-Mann, LH; Murray, V; Taylor, CB	1
Beijnen, JH; Derissen, EJ; Huitema, AD; Jacobs, BA; Rosing, H; Schellens, JH	1
Beumer, JH; Eiseman, JL; Holleran, JL; Kummar, S; Parise, RA	1
Andersen, EC; García-González, AP; Ritter, AD; Shrestha, S; Walhout, AJM; Yilmaz, LS	1
Allen, PJ; Balachandran, VP; Boucher, T; Capanu, M; Cercek, A; Chou, JF; D'Angelica, MI; DeMatteo, RP; Jarnagin, WR; Kemeny, NE; Kingham, TP; Pak, LM	1
Aviñó, A; Eritja, R; Fàbrega, C; Jorge, AF; Pais, AACC	1
Carlsson, G; Gustavsson, B; Odin, E; Taflin, H; Tell, R; Wettergren, Y	1
Aziz, MY; Azizi, J; Kamaruzaman, S; Keyon, ASA; Mohamad Zain, NN; Noordin, SS; Saad, B; Semail, NF; Waras, MN; Yahaya, N	1
Clua, A; Eritja, R; Fàbrega, C; García-Chica, J; Grijalvo, S	1
Cui, S; Jiang, L; Liu, X; Luo, D; Lv, Q; Pan, T; Qu, X; Wan, S; Yuan, W	1

Reviews

4 review(s) available for deoxyuridine and fluorouracil

Article	Year
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate	1992
Thymidylate synthetase. Advances in enzymology and related areas of molecular biology, 1973, Volume: 38 Topics: Animals; Binding Sites; Deoxyuridine; Drug Stability; Escherichia coli; Fluorouracil; Folic Acid Deficiency; Genes, Regulator; Hot Temperature; Hydrogen; Kinetics; Methyltransferases; Mutation; Neoplasms; Protein Binding; Protein Conformation; Salmonella typhimurium; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrahydrofolates; Thymidylate Synthase; Thymine	1973
Perspective on the design and biochemical pharmacology of inhibitors of thymidylate synthetase. Journal of medicinal chemistry, 1980, Volume: 23, Issue:2 Topics: Antineoplastic Agents; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Methyltransferases; Protein Binding; Structure-Activity Relationship; Thymidylate Synthase; Uracil	1980
The deoxyuridine suppression test: a review of its clinical and research applications. Clinical and laboratory haematology, 1981, Volume: 3, Issue:1 Topics: Alcoholism; Anemia, Hemolytic; Anticonvulsants; Bone Marrow Cells; Bone Marrow Diseases; Cells; Deoxyuridine; Erythrocytes, Abnormal; Female; Fluorouracil; Folic Acid; Folic Acid Deficiency; Formyltetrahydrofolates; Homocysteine; Humans; Hypothyroidism; Lymphocyte Activation; Methionine; Pregnancy; Pregnancy Complications; Statistics as Topic; Tetrahydrofolates; Vitamin B 12; Vitamin B 12 Deficiency	1981

Trials

4 trial(s) available for deoxyuridine and fluorouracil

Article	Year
Patterns of elevation of plasma 2'-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:1 Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Colorectal Neoplasms; Deoxyuridine; Enzyme Inhibitors; Fluorouracil; Humans; Infusions, Intravenous; Quinazolines; Thiophenes; Thymidylate Synthase	2002
Single ascending dose tolerability, pharmacokinetic-pharmacodynamic study of dihydropyrimidine dehydrogenase inhibitor Ro 09-4889. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7 Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Deoxycytidine; Deoxyuridine; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Leukocytes, Mononuclear; Male; Models, Chemical; Placebos; Time Factors; Uracil	2004
Prospective phase II trial of combination hepatic artery infusion and systemic chemotherapy for unresectable colorectal liver metastases: Long term results and curative potential. Journal of surgical oncology, 2018, Volume: 117, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Deoxyuridine; Disease-Free Survival; Female; Fluorouracil; Hepatic Artery; Humans; Infusions, Intra-Arterial; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Survival Rate; Treatment Outcome	2018
Plasma deoxyuridine as a surrogate marker for toxicity and early clinical response in patients with metastatic colorectal cancer after 5-FU-based therapy in combination with arfolitixorin. Cancer chemotherapy and pharmacology, 2021, Volume: 87, Issue:1 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Chromatography, Liquid; Colorectal Neoplasms; Deoxyuridine; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Male; Middle Aged; Sex Factors; Tandem Mass Spectrometry; Tetrahydrofolates	2021

Other Studies

101 other study(ies) available for deoxyuridine and fluorouracil

Article	Year
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides. Journal of medicinal chemistry, 1978, Volume: 21, Issue:11 Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication	1978
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds	1990
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Effect of deoxyuridine coadministration on toxicity and antitumor activity of fluorouracil and floxuridine. Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:6 Topics: Animals; Antineoplastic Agents; Biological Assay; Deoxyuridine; Drug Combinations; Drug Synergism; Female; Floxuridine; Fluorouracil; Lethal Dose 50; Mice; Sarcoma 180; Skin Neoplasms	1975
Toxoplasma gondii: characterization of a mutant resistant to 5-fluorodeoxyuridine. Experimental parasitology, 1977, Volume: 42, Issue:1 Topics: Animals; Cell Line; Deoxyuridine; DNA; Drug Resistance; Floxuridine; Fluorouracil; Genes; Mutation; RNA; Thymidine; Toxoplasma; Uridine	1977
Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques. The Journal of biological chemistry, 1979, Jun-25, Volume: 254, Issue:12 Topics: Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Chromatography, High Pressure Liquid; Deoxyuridine; Floxuridine; Fluorouracil; Kinetics; Mice; Thymidine; Uridine	1979
Effects of 5-fluorouracil on the cell kinetic and growth parameters of hepatoma 3924A. British journal of cancer, 1975, Volume: 32, Issue:1 Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Connective Tissue; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Fluorouracil; Kinetics; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Rats, Inbred ACI	1975
Utilization of 3H from deoxyuridine and thymidine for synthesis of DNA and tother macromolecules in various organs of the rat. Biochemical pharmacology, 1977, Jan-01, Volume: 26, Issue:1 Topics: Animals; Bone Marrow; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Fluorouracil; Intestinal Mucosa; Liver; Liver Neoplasms; Rats; Rats, Inbred ACI; RNA; Thymidine; Tritium	1977
Differential recovery of intestine, bone marrow, and thymus of rats with solid tumors following 5-fluorouracil administration. Cancer biochemistry biophysics, 1976, Volume: 1, Issue:6 Topics: Animals; Bone Marrow; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Female; Fluorouracil; Intestinal Mucosa; Liver Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred ACI; Thymus Gland; Tibia; Time Factors	1976
Metabolism of 5-fluorouracil in sensitive and resistant Novikoff hepatoma cells. The Journal of biological chemistry, 1977, Feb-10, Volume: 252, Issue:3 Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxyuridine; DNA Replication; Drug Resistance; Fluorouracil; Hydroxyurea; Kinetics; Liver Neoplasms; Mutation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Transcription, Genetic	1977
Studies of the antitumor action of 5-fluorouracil (FU). Bulletin du cancer, 1979, Volume: 66, Issue:1 Topics: Animals; Antineoplastic Agents; Bone Marrow; Carcinoma 256, Walker; Colonic Neoplasms; Deoxyuridine; DNA; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestine, Small; Leukemia L1210; Mice; Rats; Ribosomes	1979
A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro. Cancer research, 1978, Volume: 38, Issue:1 Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; In Vitro Techniques; Methotrexate; Mice; Pyrimidines; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Thymidine Monophosphate	1978
Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors. Cancer research, 1978, Volume: 38, Issue:8 Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Deoxyuracil Nucleotides; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Fluorodeoxyuridylate; Fluorouracil; Intestine, Small; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Rats	1978
Effects of 5-fluorouracil on human colon carcinoma and solid rat Walker 256 carcinosarcoma: evaluation as in vitro predictors of clinical response. Cancer treatment reports, 1978, Volume: 62, Issue:7 Topics: Animals; Carcinoma 256, Walker; Colonic Neoplasms; Deoxyuridine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; In Vitro Techniques; Mice; Ribosomes	1978
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells. Arzneimittel-Forschung, 1975, Volume: 25, Issue:3 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine	1975
In vitro biological evaluation of the R and S isomers of 1-(Tetrahydrofuran-2-yl)-5-fluorouracil. Cancer research, 1975, Volume: 35, Issue:5 Topics: Animals; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fibroblasts; Fluorouracil; Furans; Isomerism; Leukemia L1210; Time Factors	1975
Comparative effects of ftorafur and 5-fluorouracil on DNA synthesis in rat small intestine. Life sciences, 1975, Nov-01, Volume: 17, Issue:9 Topics: Animals; Deoxyuridine; DNA; Fluorouracil; Furans; Intestine, Small; Male; Rats; Thymidine; Thymidylate Synthase	1975
Kinetic alterations induced by 5-fluorouracil in bone marrow, intestinal mucosa, and tumor. Cancer research, 1976, Volume: 36, Issue:5 Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Mucosa; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Thymidine	1976
In vitro antiproliferative and metabolic activity of eight novel 5-fluorinated uracil nucleosides. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:3 Topics: Colonic Neoplasms; Deoxyuridine; DNA; Fluorouracil; Head and Neck Neoplasms; Humans; Mitosis; Stereoisomerism; Tumor Cells, Cultured	1991
Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium. The American journal of clinical nutrition, 1991, Volume: 53, Issue:6 Topics: Animals; Cells, Cultured; Colon; Deoxyuridine; DNA; Epithelium; Fluorouracil; Folic Acid; Male; Rats; Rats, Inbred Strains; Thymidine	1991
Comparative effect of 6S, 6R and 6RS leucovorin on methotrexate rescue and on modulation of 5-fluorouracil. British journal of cancer, 1991, Volume: 63, Issue:6 Topics: Analysis of Variance; Cell Line; Cell Survival; Deoxyuridine; DNA Replication; Fluorouracil; Humans; Leucovorin; Methotrexate; Stereoisomerism; Tumor Stem Cell Assay	1991
The effect of 5-fluorouracil on inhibition of epidermal DNA synthesis in vivo: a comparison of the effect of formulations and a prodrug of 5-FU. Archives of dermatological research, 1990, Volume: 282, Issue:7 Topics: Administration, Cutaneous; Animals; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Fluorouracil; Mice; Mice, Nude; Prodrugs	1990
Interaction of deoxyuridine with fluorouracil and dipyridamole in a human colon cancer cell line. Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1 Topics: Cell Survival; Colonic Neoplasms; Deoxyuracil Nucleotides; Deoxyuridine; Dipyridamole; DNA; DNA Damage; Drug Interactions; Fluorouracil; Humans; RNA; Tumor Cells, Cultured	1989
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase. Journal of surgical oncology, 1989, Volume: 42, Issue:3 Topics: Animals; Colon; Deoxyuridine; Digestive System; Digestive System Neoplasms; Fluorouracil; Humans; Liver; Mice; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rectum; Species Specificity; Stomach; Substrate Specificity; Thymidine; Uridine	1989
Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells. Biochemical pharmacology, 1989, Oct-01, Volume: 38, Issue:19 Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Esters; Fluorodeoxyuridylate; Fluorouracil; Mice; Thymidine; Thymidine Monophosphate	1989
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies. Cancer research, 1986, Volume: 46, Issue:6 Topics: Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Mice; Quinazolines; Thymidylate Synthase; Tritium	1986
Alteration of fluorouracil metabolism in human colon cancer cells by dipyridamole with a selective increase in fluorodeoxyuridine monophosphate levels. Cancer research, 1986, Volume: 46, Issue:12 Pt 1 Topics: Cells, Cultured; Colonic Neoplasms; Deoxyuracil Nucleotides; Deoxyuridine; Dipyridamole; DNA; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Ribonucleotides; Time Factors; Uridine Triphosphate	1986
Moderate antiproliferative effect of the antifolate CB3717 in the BN myeloid leukaemia model. British journal of cancer, 1988, Volume: 57, Issue:4 Topics: Animals; Antineoplastic Agents; Deoxyuridine; DNA; Fluorouracil; Folic Acid; Folic Acid Antagonists; Leukemia, Myeloid, Acute; Quinazolines; Rats; Thymidine Monophosphate; Thymidylate Synthase	1988
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents. Biochemical pharmacology, 1967, Volume: 16, Issue:4 Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine	1967
Determinants of responsiveness to 5-fluorouridine in transplantable murine leukemias. Molecular pharmacology, 1971, Volume: 7, Issue:2 Topics: Animals; Antineoplastic Agents; Biodegradation, Environmental; Biological Transport; Cell Line; Cell Survival; Cells, Cultured; Deoxyuridine; DNA Replication; DNA, Neoplasm; Drug Resistance; Floxuridine; Fluorine; Fluorouracil; Leukemia, Experimental; Mice; Neoplasm Transplantation; Pentosyltransferases; Phosphotransferases; Uridine	1971
Metabolism of pyrimidines and pyrimidine nucleosides by Salmonella typhimurium. Journal of bacteriology, 1972, Volume: 110, Issue:1 Topics: Aminohydrolases; Cytidine; Cytosine; Deoxyuridine; Floxuridine; Flucytosine; Fluorouracil; Genetics, Microbial; Genotype; Mutation; Nucleosides; Nucleotidyltransferases; Pentosyltransferases; Phosphotransferases; Pyrimidines; Salmonella typhimurium; Thymidine; Uracil; Uracil Nucleotides; Uridine	1972
5-Fluorouracil and derivatives in cancer chemotherapy. II. Possible in vivo formation and stabilization of 5-fluoro-2'-deoxyuridine. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:10 Topics: Biopharmaceutics; Biotransformation; Chromatography, Thin Layer; Deoxyuridine; Dialysis; Drug Stability; Floxuridine; Fluorouracil; Humans; Neoplasms; Spectrophotometry, Ultraviolet	1972
Complex formation of uracil, 2'-deoxyuridine and their 5-halogenated derivatives. Biochimica et biophysica acta, 1973, Apr-11, Volume: 299, Issue:4 Topics: Bromodeoxyuridine; Bromouracil; Chemical Phenomena; Chemistry; Copper; Deoxyuridine; Drug Stability; Floxuridine; Fluorouracil; Idoxuridine; Mathematics; Nickel; Potentiometry; Silver; Uracil	1973
5-Fluorouracil and derivatives in cancer chemotherapy. 3. In vivo enhancement of antitumor activity of 5-fluorouracil (FU) and 5-fluoro-2'-deoxyuridine (FUDR). Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:12 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Deoxycytidine; Deoxyuridine; Dialysis; Drug Synergism; Drug Therapy, Combination; Floxuridine; Fluorouracil; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Homologous	1973
Assay of 5-fluorodeoxyuridine 5'-monophosphate deoxyuridine 5'-monophosphate pools following 5-fluorouracil. Cancer research, 1974, Volume: 34, Issue:10 Topics: Animals; Cell Line; Clinical Enzyme Tests; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Floxuridine; Fluorouracil; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Mice; Neoplasms, Experimental; Phosphates; Thymidylate Synthase	1974
In vitro and in vivo virostatic properties of alkylated pyrimidines against DNA and RNA viruses. Chemotherapy, 1969, Volume: 14, Issue:3 Topics: Animals; Antiviral Agents; Deoxyuridine; DNA Viruses; Fluorouracil; Friend murine leukemia virus; Kidney; Mice; Pyrimidines; Rabbits; RNA Viruses; Simplexvirus; Spleen; Time Factors; Uracil; Vaccinia virus	1969
Chemical induction of focus-forming virus from nonproducer cells transformed by murine sarcoma virus. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:12 Topics: Amines; Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytosine Nucleotides; Deoxyuridine; Fluorouracil; Gammaretrovirus; Helper Viruses; Iodine; Mercaptopurine; Mice; Moloney murine leukemia virus; Rats; Rauscher Virus; Time Factors; Virus Replication	1971
The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells. Journal of cellular physiology, 1974, Volume: 83, Issue:3 Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cells, Cultured; Cytochalasin B; Deoxyribonucleosides; Deoxyuridine; Depression, Chemical; Dipyridamole; Fluorouracil; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Time Factors; Tritium	1974
[Characteristics of the cell mitotic cycle and the possibility of enhancing the effect of radiotherapy]. Meditsinskaia radiologiia, 1974, Volume: 19, Issue:6 Topics: Animals; Cell Survival; Cells, Cultured; Chromosome Aberrations; Deoxyuridine; DNA, Neoplasm; Esophageal Neoplasms; Fluorouracil; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Mitosis; Neoplasms; Neoplasms, Experimental	1974
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil. Cancer research, 1973, Volume: 33, Issue:12 Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium	1973
[Mechanism of action of ftorafur, a new antineoplastic agent]. Voprosy meditsinskoi khimii, 1972, Volume: 18, Issue:3 Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Formates; Hot Temperature; In Vitro Techniques; Leukemia, Experimental; Mice; Neoplasm Transplantation; Orotic Acid; Pentosyltransferases; RNA, Neoplasm; Sarcoma 37; Spectrum Analysis; Uracil; Uridine	1972
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions. Cancer chemotherapy reports, 1973, Volume: 57, Issue:1 Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Neoplasms; Penicillamine; Thymidine; Time Factors; Tritium	1973
Morphogenic effects of halogenated thymidine analogs on Drosophila. 3. 5-Iododeoxyuridine. Experientia, 1972, Mar-15, Volume: 28, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Centrifugation, Density Gradient; Deoxyuridine; DNA; Drosophila; Fluorouracil; Larva; Thymidine; Tritium	1972
In vivo prediction of drug sensitivity with cancer-seeking isotopes. National Cancer Institute monograph, 1971, Volume: 34 Topics: Amides; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Deoxyuridine; Diethylstilbestrol; Female; Fluorouracil; Fluoxymesterone; Humans; Imidazoles; Iodine Radioisotopes; Methotrexate; Neoplasms; Nitrosourea Compounds; Phosphates; Rats; Serum Albumin, Radio-Iodinated; Sodium Isotopes; Triazenes; Vincristine	1971
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism. Cancer research, 1969, Volume: 29, Issue:7 Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines	1969
Cytostatic and immunologic activity of 5-mercaptouracil desoxyriboside in the management of multiple superficial basal cell epitheliomas. Journal of medicine, 1970, Volume: 1, Issue:3 Topics: Antimetabolites; Carcinoma, Basal Cell; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; Hypersensitivity, Delayed; Skin Neoplasms; Sulfhydryl Compounds; Uridine	1970
Fluorouracil: mechanism of action in human skin and actinic keratoses. I. Effect on DNA synthesis in vivo. Archives of dermatology, 1970, Volume: 101, Issue:2 Topics: Chemical Phenomena; Chemistry; Deoxyuridine; DNA; Fluorouracil; Humans; Injections, Intradermal; Injections, Intravenous; Keratosis; Ligases; Nucleotides; Skin; Tritium	1970
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results. The American journal of roentgenology, radium therapy, and nuclear medicine, 1968, Volume: 102, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; Female; Fluorouracil; Folic Acid; Humans; India; Leukocyte Count; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Radioisotope Teletherapy; Radiotherapy Dosage	1968
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow. The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24 Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuridine; DNA; Erythrocytes; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Nucleotides; Oxidation-Reduction; Pyrimethamine; Thymidine; Tritium	1969
Antiglycolytic activities of 5-fluorouracil and related pyrimidines in mouse ascites carcinoma cells with special reference to inorganic phosphate and glucose. Oncology, 1969, Volume: 23, Issue:1 Topics: Adenine; Animals; Arsenic; Carcinoma, Ehrlich Tumor; Carcinoma, Krebs 2; Deoxyuridine; Fluorouracil; Fructose; Glucose; Glutamine; Glycolysis; In Vitro Techniques; Manometry; Mice; Nucleosides; Phenols; Phosphates; Pyrimidines; Pyruvates; Respiration; Succinates; Uracil; Uridine	1969
Immunobiological studies with the virostatics 5-ethyl-2'-deoxyuridine (EDU) and 1-allyl-3,5-diethyl-6-chlorouracil (ACIU). Chemotherapy, 1969, Volume: 14, Issue:3 Topics: Animals; Antibody Formation; Antiviral Agents; Deoxyuridine; Erythrocytes; Female; Fluorouracil; Hemagglutination; Hemolysin Proteins; Immunosuppressive Agents; Male; Mice; Sheep; Uracil	1969
The influence of methotrexate pretreatment on 5-fluorouracil metabolism in L1210 cells. The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4 Topics: Animals; Biological Transport; Deoxyuridine; Fluorouracil; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Phosphoribosyl Pyrophosphate; Purines; RNA, Neoplasm	1981
Assessment of growth-limiting events caused by 5-fluorouracil in mouse cells and in human cells. Cancer research, 1980, Volume: 40, Issue:11 Topics: Animals; Cell Division; Cells, Cultured; Deoxyribonucleotides; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Fluorouracil; Humans; Methyltransferases; Mice; RNA; Sarcoma, Experimental; Thymidine Monophosphate; Thymidylate Synthase	1980
Uridine rescue from the lethal toxicity of 5-fluorouracil in mice. Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:1 Topics: Animals; Deoxyuridine; Fluorouracil; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; RNA; Thymidine; Uridine	1982
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment. Cancer research, 1982, Volume: 42, Issue:9 Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine	1982
Rate-limiting steps in the interactions of fluoropyrimidines and methotrexate. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:5 Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Methotrexate; Mice; Neoplasm Proteins; RNA, Neoplasm; Thymidine Monophosphate	1984
Potentiation of the antitumor action of 5-fluorouracil with 5-ethyl-2'-deoxyuridine in human colorectal tumor xenografts. Oncology, 1984, Volume: 41, Issue:3 Topics: Adenocarcinoma, Mucinous; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colonic Neoplasms; Deoxyuridine; Drug Synergism; Fluorouracil; Humans; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Rectal Neoplasms; RNA, Neoplasm; Transplantation, Heterologous	1984
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy]. Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3 Pt 2 Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine	1984
Fluorinated pyrimidine nucleosides. 4. Synthesis and antitumor testing of a series of 2',5'-dideoxy- and 2',3',5'-trideoxynucleosides of 5-fluorouracil. Journal of medicinal chemistry, 1980, Volume: 23, Issue:8 Topics: Animals; Antineoplastic Agents; Deoxyuridine; Floxuridine; Fluorouracil; Mice; Sarcoma 180; Tegafur	1980
Abnormal deoxyuridine suppression as a rapid predictor for antimetabolite chemosensitivity: correlation with in vitro tests of growth inhibition. Cancer treatment reports, 1984, Volume: 68, Issue:4 Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Colony-Forming Units Assay; Deoxyuridine; DNA; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; Leukemia L1210; Methotrexate; Mice; Ovarian Neoplasms; Tumor Stem Cell Assay	1984
Assessment of antimetabolite cytotoxicity: a comparison of clonogenic assays and tritiated deoxyuridine incorporation. European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:3 Topics: Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Humans; Leukemia L1210; Melanoma; Methotrexate; Mice; Tritium	1983
Human tissues degrade uridine much less than thymidine. Possible consequence for 5-fluorouracil therapy. Biochemical pharmacology, 1984, Mar-01, Volume: 33, Issue:5 Topics: Animals; Deoxyuridine; Fluorouracil; Humans; In Vitro Techniques; Liver; Mice; Models, Biological; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Spleen; Thymidine; Tissue Distribution; Uridine	1984
[Studies in vivo and in vitro on the influence of 5-fluorouracil and n'-(2'-furanidyl)-5-fluorouracil on the walker carcinosarcoma 256 in the rat (author's transl)]. Arzneimittel-Forschung, 1980, Volume: 30, Issue:6 Topics: Animals; Carcinoma 256, Walker; Deoxyuridine; Dose-Response Relationship, Drug; Fluorouracil; Male; Rats; Tegafur	1980
Increased uptake of 5-fluorouracil by Ehrlich ascites tumor cells with some additives and metabolite analysis. Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:11 Topics: Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Cell Membrane Permeability; Deoxyuridine; Detergents; Edetic Acid; Fluorouracil; Male; Mice; Mice, Inbred Strains; Polyamines; Ribosemonophosphates; RNA, Neoplasm; Uridine	1982
Use of uridine rescue to enhance the antitumor selectivity of 5-fluorouracil. Cancer research, 1983, Volume: 43, Issue:7 Topics: Animals; Bone Marrow; Deoxyuridine; Drug Therapy, Combination; Fluorouracil; Infusions, Parenteral; Injections, Intraperitoneal; Leukemia L1210; Male; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uridine	1983
Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil. Cancer research, 1981, Volume: 41, Issue:9 Pt 1 Topics: Animals; Carcinoma; Cell Line; Deoxyribonucleosides; Deoxyribose; Deoxyuridine; Drug Synergism; Fluorouracil; Humans; Inosine; Leucovorin; Mice; Sarcoma, Experimental; Thymidine; Thymidylate Synthase	1981
The enhancement of 5-fluorouracil anti-metabolic activity by leucovorin, menadione and alpha-tocopherol. European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:7 Topics: Animals; Antimetabolites; Cell Count; Cell Division; Cell Line; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Interactions; Fluorouracil; Folic Acid; Leucovorin; Leukemia, Erythroblastic, Acute; Mice; Vitamin E; Vitamin K	1982
Additive formation of antineoplastic 5-fluorouracil nucleosides from 5-fluorouracil by Ehrlich ascites tumor extracts in the presence of ribose 1-phosphate/uridine or deoxyribose 1-phosphate/deoxyuridine. Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:9 Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Deoxyuridine; Fluorouracil; In Vitro Techniques; Liver; Male; Mice; Ribosemonophosphates; Uridine	1982
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro. European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12 Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Methotrexate; Thymidine	1981
Increased formation of 5-fluoro-2'-deoxyuridine 5'-monophosphate from 5-fluorouracil in the presence of 2-deoxy-alpha-D-ribose 1-phosphate and 2'-deoxyuridine in Ehrlich ascites tumor cells. Nucleic acids symposium series, 1980, Issue:8 Topics: Animals; Carcinoma, Ehrlich Tumor; Deoxyuracil Nucleotides; Deoxyuridine; Fluorodeoxyuridylate; Fluorouracil; Kinetics; Mice; Pentosephosphates; Ribosemonophosphates	1980
5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. Cancer research, 1995, Aug-15, Volume: 55, Issue:16 Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma; Cell Division; Colonic Neoplasms; Deoxyuridine; Drug Synergism; Fluorouracil; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Interferon alpha-2; Interferon-alpha; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Recombinant Proteins; RNA, Messenger; Thymidine Phosphorylase; Tumor Cells, Cultured	1995
Increased chemocytotoxicity to colon cancer cells by shock wave-induced cavitation. Gastroenterology, 1994, Volume: 106, Issue:4 Topics: Air; Carcinoma; Cell Cycle; Cell Survival; Colonic Neoplasms; Combined Modality Therapy; Deoxyuridine; Fluorouracil; Humans; Microspheres; Thymidylate Synthase; Tumor Cells, Cultured; Ultrasonic Therapy	1994
In vitro antitumour activity of cis- and trans-5-fluoro-5,6-dihydro-6-alkoxy-uracils; effects on thymidylate synthesis. British journal of cancer, 1993, Volume: 68, Issue:4 Topics: Carcinoma, Squamous Cell; Cell Division; Deoxyuridine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Laryngeal Neoplasms; Mouth Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured	1993
Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 1997, May-13, Volume: 94, Issue:10 Topics: Base Composition; Base Sequence; Binding Sites; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease I; Deoxyuridine; DNA; DNA Damage; DNA Repair; Drug Design; Endodeoxyribonucleases; Enzyme Inhibitors; Fluorouracil; Humans; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Substrate Specificity	1997
Effect of ethyldeoxyuridine on 5-fluorouracil-induced neutropenia. Acta physiologica Hungarica, 1996, Volume: 84, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Deoxyuridine; Female; Fluorouracil; Leukocyte Count; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neutropenia	1996
5-ethyl-2'-deoxyuridine, a modulator of both antitumour action and pharmacokinetics of 5-fluorouracil. Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:12 Topics: Animals; Antimetabolites, Antineoplastic; Area Under Curve; Colonic Neoplasms; Deoxyuridine; Dose-Response Relationship, Drug; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Time Factors; Treatment Outcome; Uracil; Uridine	1999
Modulation of 5-fluorouracil by 5-ethyl-2'-deoxyuridine on cell lines expressing different dihydropyrimidine dehydrogenase activities. Anti-cancer drugs, 1999, Volume: 10, Issue:6 Topics: Antimetabolites, Antineoplastic; Cell Line; Deoxyuridine; Dihydrouracil Dehydrogenase (NADP); Drug Screening Assays, Antitumor; Fluorouracil; Humans; Oxidoreductases; Pentosyltransferases; Pyrimidine Phosphorylases; Thymidine Kinase; Thymidylate Synthase; Tumor Cells, Cultured	1999
Growth inhibition of a human tumor cell strain by 5-fluorouracil, 5-fluorouridine, and 5-fluoro-2'-deoxyuridine; reversal studies. Cancer research, 1958, Volume: 18, Issue:6 Topics: Antineoplastic Agents; Deoxyuridine; Fluorouracil; Humans; Nucleosides; Nucleotides; Uridine	1958
The clinical effects of the continuous administration of fluorinated pyrimidines (5-fluorouracil and 5-fluoro-2'-deoxyuridine). Cancer chemotherapy reports, 1960, Volume: 8 Topics: Deoxyuridine; Fluorouracil; Halogenation; Neoplasms; Nucleosides; Nucleotides; Pyrimidines	1960
The clinical evaluation of 5-fluorouracil and 5-fluoro-2'-deoxyuridine in solid tumors in adults: a progress report. Cancer chemotherapy reports, 1960, Volume: 6 Topics: Antineoplastic Agents; Deoxyuridine; Fluorouracil; Neoplasms; Nucleosides; Nucleotides; Research Report; Uracil	1960
Comparison of 5-fluorouracil and 5-fluoro-2'-deoxyuridine in the treatment of far-advanced breast and colon lesions. Cancer chemotherapy reports, 1962, Volume: 16 Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Deoxyuridine; Fluorouracil; Humans; Nucleosides; Nucleotides; Uracil	1962
Effects of uracil and thymidine on the development of resistance to 5-fluorouracil in Pediococcus cerevisiae. Journal of bacteriology, 1963, Volume: 85 Topics: Deoxyuridine; Fluorouracil; Pediococcus; Thymidine; Uracil	1963
Ineffectiveness of 5-fluoro-2'-deoxyuridine in man after failure of 5-fluorouracil. Cancer chemotherapy reports, 1963, Volume: 28 Topics: Deoxyuridine; Floxuridine; Fluorouracil; Folic Acid; Humans	1963
THE EFFECT OF NATURAL AND UNNNATURAL PYRIMIDINES AND PYRIMIDINE NUCLEOSIDES ON THE PHOSPHOROLYSIS OF 5-IODODEOXYURIDINE BY MOUSE LIVER EXTRACT. Biochemical pharmacology, 1964, Volume: 13 Topics: Animals; Chromatography; Deoxyuridine; Floxuridine; Fluorouracil; Idoxuridine; Iodine Isotopes; Liver; Liver Extracts; Metabolism; Mice; Nucleosides; Pharmacology; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Thymine; Uracil	1964
COMPARISON OF 5-FLUOROURACIL (NSC-19893) AND 2'-DEOXY-5-FLUOROURIDINE (NSC-27640) IN TREATMENT OF PATIENTS WITH ADVANCED ADENOCARCINOMA OF COLON OR RECTUM. Cancer chemotherapy reports, 1965, Volume: 44 Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Deoxyuridine; Drug Therapy; Fluorouracil; Humans; Nucleosides; Palliative Care; Rectal Neoplasms; Rectum; Toxicology; Uridine	1965
Studies on the feasibility of adjuvant chemotherapy with 5-fluorouracil (FU) and 5-fluoro-2'-deoxyuridine (FUDR) in the immediate postoperative period. Archives of surgery (Chicago, Ill. : 1960), 1962, Volume: 85 Topics: Antineoplastic Agents; Chemotherapy, Adjuvant; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Postoperative Period; Pyrimidines; Uracil	1962
In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2'-deoxyuridine activated by hypoxic irradiation. International journal of radiation oncology, biology, physics, 2004, Feb-01, Volume: 58, Issue:2 Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Deoxyuridine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Fluorouracil; Mice; Mice, Inbred BALB C; Prodrugs	2004
[Potentiation of 5-fluorouracil efficacy. Molecular mechanisms playing a role in the cytotoxic action of 5-fluorouracil and 5-ethyl-2'-deoxyuridine (EUdR) combination]. Magyar onkologia, 2004, Volume: 48, Issue:3 Topics: Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Deoxyuridine; DNA Fragmentation; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Fluorouracil; Humans; Microscopy, Fluorescence; Proliferating Cell Nuclear Antigen; Time Factors; Tumor Suppressor Protein p53	2004
Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Jun-05, Volume: 820, Issue:1 Topics: Atmospheric Pressure; Capecitabine; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; Drug Stability; Fluorouracil; Humans; Mass Spectrometry; Neoplasms; Reproducibility of Results; Sensitivity and Specificity	2005
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients. British journal of clinical pharmacology, 2007, Volume: 63, Issue:1 Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Female; Fluorouracil; Humans; Male; Thymidine	2007
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo. FEMS microbiology letters, 2007, Volume: 270, Issue:1 Topics: Azacitidine; Bromodeoxyuridine; Decitabine; Deoxyuridine; DNA Damage; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Models, Biological; Molecular Structure; Mutation; N-Glycosyl Hydrolases; Nucleotidases; Orotic Acid; Substrate Specificity; Thymidine Monophosphate; Uridine	2007
Association of thymidylate synthase enhancer region polymorphisms with thymidylate synthase activity in vivo. The pharmacogenomics journal, 2011, Volume: 11, Issue:4 Topics: Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Cohort Studies; Colorectal Neoplasms; Deoxyuridine; Enhancer Elements, Genetic; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genotype; HCT116 Cells; HeLa Cells; Humans; Male; Middle Aged; New South Wales; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Tandem Repeat Sequences; Thymidylate Synthase; Transfection; Upstream Stimulatory Factors	2011
Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy. Molecular microbiology, 2013, Volume: 90, Issue:2 Topics: Amides; Animals; Biological Transport; Cell Line; Deoxyuridine; Fluorouracil; Gene Knockout Techniques; Mice; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Transfection; Trypanocidal Agents; Trypanosoma brucei brucei; Uracil; Uridine; Uridine Monophosphate; Virulence	2013
The influence of p53 status on the cytotoxicity of fluorinated pyrimidine L-nucleosides. Chemico-biological interactions, 2015, Oct-05, Volume: 240 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Deoxyuridine; Fluorouracil; Inhibitory Concentration 50; Mice; Molecular Structure; Pyrimidine Nucleosides; Tumor Suppressor Protein p53	2015
Exploring the intracellular pharmacokinetics of the 5-fluorouracil nucleotides during capecitabine treatment. British journal of clinical pharmacology, 2016, Volume: 81, Issue:5 Topics: Antimetabolites, Antineoplastic; Area Under Curve; Capecitabine; Chromatography, Liquid; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Deoxyuracil Nucleotides; Deoxyuridine; Fluorouracil; Humans; Leukocytes, Mononuclear; Neoplasms; Tandem Mass Spectrometry; Uridine Triphosphate	2016
LC-MS/MS assay for the quantitation of FdCyd and its metabolites FdUrd and FU in human plasma. Journal of pharmaceutical and biomedical analysis, 2016, Sep-10, Volume: 129 Topics: Biological Assay; Chromatography, Liquid; Deoxyuridine; Fluorouracil; Humans; Plasma; Tandem Mass Spectrometry; Tetrahydrouridine	2016
Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics. Cell, 2017, 04-20, Volume: 169, Issue:3 Topics: Animals; Antineoplastic Agents; Caenorhabditis elegans; Camptothecin; Colorectal Neoplasms; Comamonas; Deoxyuridine; Diet; Escherichia coli; Fluorouracil; Gastrointestinal Microbiome; Humans; Models, Animal; Pyrimidine Nucleosides	2017
DNA-based nanoscaffolds as vehicles for 5-fluoro-2'-deoxyuridine oligomers in colorectal cancer therapy. Nanoscale, 2018, Apr-19, Volume: 10, Issue:15 Topics: Cell Line, Tumor; Cholesterol; Colorectal Neoplasms; Deoxyuridine; DNA; Drug Resistance, Neoplasm; Fluorouracil; Humans; Nanostructures	2018
A simple and efficient sequential electrokinetic and hydrodynamic injections in micellar electrokinetic chromatography method for quantification of anticancer drug 5-fluorouracil and its metabolite in human plasma. Biomedical chromatography : BMC, 2021, Volume: 35, Issue:5 Topics: Antineoplastic Agents; Chromatography, Micellar Electrokinetic Capillary; Deoxyuridine; Fluorouracil; Humans	2021
Parallel G-quadruplex Structures Increase Cellular Uptake and Cytotoxicity of 5-Fluoro-2'-deoxyuridine Oligomers in 5-Fluorouracil Resistant Cells. Molecules (Basel, Switzerland), 2021, Mar-20, Volume: 26, Issue:6 Topics: Cytotoxins; Deoxyuridine; Drug Resistance, Neoplasm; Fluorouracil; G-Quadruplexes; HeLa Cells; HT29 Cells; Humans; Neoplasms	2021
Novel ProTide prodrugs of 5-fluoro-2'-deoxyuridine for the treatment of liver cancer. European journal of medicinal chemistry, 2023, Nov-15, Volume: 260 Topics: Deoxyuridine; Fluorouracil; Humans; Liver Neoplasms; Prodrugs	2023