deoxyuridine has been researched along with brivudine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (68.75) | 18.7374 |
| 1990's | 10 (31.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH | 1 |
| Andrei, G; Balzarini, J; Claes, P; De Clercq, E; Rozenski, J; Snoeck, R; Van Aerschot, A; Van Meervelt, L; Verheggen, I; Wiebe, L | 1 |
| Gati, WP; Knaus, EE; Kumar, P; Singh, S; Tandon, M; Tempest, ML; Wiebe, LI; Xu, L | 1 |
| Claes, P; De Clercq, E; Herdewijn, P; Pannecouque, C; Snoeck, R; Wigerinck, P | 1 |
| Aduma, PJ; De Clercq, E; Gupta, SV | 1 |
| De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P; Vanderhaeghe, H | 1 |
| Gentry, GA; Veerisetty, V | 3 |
| De Clercq, E; Desgranges, C; Herdewijn, P; Jones, AS; McLean, MJ; Sim, IS; Walker, RT | 1 |
| Belloc, I; Bricaud, H; De Clercq, E; Desgranges, C; Drouillet, F; Razaka, G | 1 |
| De Clercq, E; Griengl, H; Rosenwirth, B; Schwarz, W; Streicher, W; Wanek, E | 1 |
| Freeman, DJ; Spruance, SL | 1 |
| Dunkel, EC; Geary, PA; Imperia, PS; Lass, JH; Lazarus, HM; Pavan-Langston, D | 1 |
| Bernaerts, R; Breemersch, M; De Clercq, E; Dieltiens, M; Maudgal, PC; Van Eeckhoutte, L | 1 |
| Bachmayer, H; Bodenteich, M; Ghazzouli, I; Griengl, H; Hayden, W; Rosenwirth, B; Streicher, W; Stütz, P; Wanek, E | 1 |
| Cheng, YC; De Clercq, E; Dutschman, G; Jones, AS; Rahim, SG; Verhelst, G; Walker, RT | 1 |
| de Clercq, E | 1 |
| Bergstrom, DE; de Clercq, E; Descamps, J; Verhelst, G | 1 |
| Allaudeen, HS; Chen, MS; De Clercq, E; Lee, JJ; Prusoff, WH | 1 |
| Cheng, YC; Dutschman, GE; Grill, SP; Schinazi, RF; Tan, RS | 1 |
| Cheng, YC; De Clercq, E; Dutschman, GE; Zou, FC | 1 |
| Balzarini, J; Bricaud, H; De Clercq, E; Desgranges, C; Rabaud, M; Razaka, G | 1 |
| Allaudeen, HS; De Clercq, E; Descamps, J; Jones, AS; Kozarich, JW; Walker, RT | 1 |
| De Clercq, E; Jones, AS; Rahim, SG; Serafinowski, P; Walker, RT | 1 |
| Creuven, I; Dory, M; Durant, F; Evrard, C; Evrard, G; Herdewijn, P; Olivier, A; van Aerschot, A; Wigerinck, P | 1 |
| Docherty, JJ; Wilber, BA | 1 |
| Clairmont, C; Hellstrand, K; Hirschberg, C; Olofsson, S; Shugar, D; Sjöblom, I | 1 |
| De Clercq, E; Huyghe, P; Maudgal, PC | 1 |
| Freytag, SO; Kim, JH; Kim, SH; Rogulski, KR | 1 |
| Focher, F; Priori, G; Spadari, S; Tondelli, L; Verri, A | 1 |
1 review(s) available for deoxyuridine and brivudine
| Article | Year |
|---|---|
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
31 other study(ies) available for deoxyuridine and brivudine
| Article | Year |
|---|---|
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds | 1990 |
Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.
Topics: Animals; Antiviral Agents; Biological Transport; Cells, Cultured; Crystallography, X-Ray; Cytopathogenic Effect, Viral; Herpesviridae; Humans; Male; Mice; Models, Molecular; Molecular Conformation; Nucleosides; RNA Viruses; Structure-Activity Relationship; Sugar Alcohols | 1995 |
Synthesis and biological activity of 5-(2,2-difluorocyclopropyl)-2'-deoxyuridine deoxyuridine diastereomers.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Cytopathogenic Effect, Viral; Deoxyuridine; Erythrocyte Membrane; Membrane Proteins; Mice; Nucleoside Transport Proteins; Simplexvirus; Stereoisomerism; Viral Plaque Assay | 1992 |
5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Herpesvirus 3, Human; Molecular Structure; Simplexvirus; Structure-Activity Relationship; Thiophenes; Virus Replication | 1991 |
Antiherpes virus activity and effect on deoxyribonucleoside triphosphate pools of (E)-5-(2-bromovinyl)-2'-deoxycytidine in combination with deaminase inhibitors.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Cytidine Triphosphate; Deoxyuridine; DNA, Viral; Dose-Response Relationship, Drug; Drug Interactions; Humans; Purine Nucleotides; Pyrimidine Nucleotides; Simplexvirus; Tetrahydrouridine; Thymine Nucleotides; Virus Replication | 1990 |
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells | 1988 |
Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Bromodeoxyuridine; Cell Division; Cell Line; Cyclopentanes; Cytopathogenic Effect, Viral; Deoxycytidine; Deoxyuridine; Herpes Simplex; Humans; Mice; Mice, Hairless; Rabbits; Rats; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Cultivation | 1985 |
HSV1-specific thymidylate kinase activity in infected cells.
Topics: Acyclovir; Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Deoxyuridine; Drug Resistance, Microbial; Herpes Simplex; Kinetics; Mice; Nucleoside-Phosphate Kinase; Phosphonoacetic Acid; Phosphorylation; Phosphotransferases; Substrate Specificity | 1985 |
Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Bromouracil; Deoxyuridine; Herpes Simplex; Mice; Mice, Inbred BALB C; Rabbits; Simplexvirus; Thymine; Uridine; Virus Replication | 1986 |
Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Bromouracil; Deoxyuridine; Half-Life; Humans; Male; Rabbits; Rats; Rats, Inbred Strains; Simplexvirus; Uracil | 1986 |
2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.
Topics: Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Floxuridine; Simplexvirus; Structure-Activity Relationship | 1987 |
Efficacy of topical treatment for herpes simplex virus infections: predictions from an index of drug characteristics in vitro.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Diffusion; Female; Guinea Pigs; Herpes Simplex; Idoxuridine; Pharmaceutical Vehicles; Skin Diseases; Trifluridine; Vidarabine | 1986 |
An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cornea; Deoxyuridine; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine | 1988 |
Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis.
Topics: Animals; Anterior Chamber; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits | 1986 |
5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue.
Topics: Animals; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Deoxyuridine; Dose-Response Relationship, Drug; Halogens; Herpes Simplex; Mice; Rats | 1985 |
Differential affinities of 5-(2-halogenovinyl)-2'-deoxyuridines for deoxythymidine kinases of various origins.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cytosol; Deoxyuridine; Herpesvirus 3, Human; Humans; Idoxuridine; In Vitro Techniques; Mitochondria; Phosphorylation; Rabbits; Simplexvirus; Substrate Specificity; Thymidine Kinase | 1981 |
5-Methoxymethyldeoxyuridine-resistant mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Line; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Guanine; Mice; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase | 1981 |
Differential inhibition of herpes simplex viruses, type 1 (HSV-1) an type 2 (HSV-2), by (E)-5-(2-X-vinyl)-2'-deoxyuridines.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Deoxyuridine; Fluorodeoxyuridylate; Idoxuridine; Rabbits; Simplexvirus; Structure-Activity Relationship | 1981 |
Incorporation of E-5-(2-halovinyl)-2'-deoxyuridines into deoxyribonucleic acids of herpes simplex virus type 1-infected cells.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Viral; Deoxyuridine; DNA Polymerase II; DNA Replication; DNA, Viral; Halogens; Idoxuridine; Kidney; Simplexvirus; Structure-Activity Relationship; Vinyl Compounds; Virus Replication | 1982 |
Virus-induced thymidine kinases as markers for typing herpes simplex viruses and for drug sensitivity assays.
Topics: Bromodeoxyuridine; Cells, Cultured; Deoxyribonucleases; Deoxyuridine; Enzyme Induction; Fluorescent Antibody Technique; HeLa Cells; Humans; Idoxuridine; Microbial Sensitivity Tests; Simplexvirus; Thymidine Kinase | 1982 |
Alterations in substrate specificity and physicochemical properties of deoxythymidine kinase of a drug-resistant herpes simplex virus type 1 mutant.
Topics: Arabinonucleosides; Blood; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Hot Temperature; Mutation; Phosphorylation; Simplexvirus; Substrate Specificity; Thymidine; Thymidine Kinase | 1983 |
Differential binding affinities of sugar-modified derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine for herpes simplex virus-induced and human cellular deoxythymidine kinases.
Topics: Bromodeoxyuridine; Cytosol; Deoxyuridine; Enzyme Induction; Humans; Mitochondria; Simplexvirus; Thymidine Kinase; Virus Replication | 1984 |
Phosphorolysis of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and other 5-substituted-2'-deoxyuridines by purified human thymidine phosphorylase and intact blood platelets.
Topics: Blood Platelets; Bromodeoxyuridine; Bromouracil; Chromatography, High Pressure Liquid; Deoxyuridine; Humans; In Vitro Techniques; Pentosyltransferases; Thymidine Phosphorylase; Thymine | 1983 |
The synthesis and properties of some 5-substituted uracil derivatives.
Topics: Bromodeoxyuridine; Chemical Phenomena; Chemistry; Coliphages; Deoxyuridine; DNA, Bacterial; DNA, Viral; Escherichia coli; Methods; Mycoplasma; Uracil | 1980 |
The synthesis and properties of some 5-substituted uracil derivatives.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Drug Evaluation, Preclinical; Herpesviridae; Structure-Activity Relationship; Uracil | 1981 |
Stereoelectronic properties of five anti-HSV-1 2'-deoxynucleosides analogues with heterocyclic substituents in the 5-position: a comparison with BVDU.
Topics: Antiviral Agents; Bromodeoxyuridine; Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Herpesvirus 1, Human; Molecular Structure; Stereoisomerism; Thermodynamics; Thiophenes; Thymidine Kinase; Viral Proteins; X-Ray Diffraction | 1994 |
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine | 1994 |
5-Propyl-2-deoxyuridine induced interference with glycosylation in herpes simplex virus infected cells. Nature of PdU-induced modifications of N-linked glycans.
Topics: Agglutinins; Animals; Antiviral Agents; Biological Transport; Bromodeoxyuridine; Cell Line; Chlorocebus aethiops; Chromatography, Affinity; Chromatography, Gel; Deoxyuridine; Glycosylation; Golgi Apparatus; Humans; Infant; Lectins; Melanoma, Experimental; Mice; Neuraminidase; Nucleoside Diphosphate Sugars; Polysaccharides; Simplexvirus; Tumor Cells, Cultured; Viral Envelope Proteins | 1993 |
Efficacy of (S)-HPMPA against thymidine kinase-deficient herpes simplex virus-keratitis.
Topics: Adenine; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Herpesvirus 1, Human; Keratitis, Herpetic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase | 1987 |
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity.
Topics: Blotting, Western; Bromodeoxyuridine; Cytosine; Cytosine Deaminase; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Flucytosine; Ganciclovir; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Humans; Nucleoside Deaminases; Prodrugs; Radiation Tolerance; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured | 1997 |
Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues.
Topics: Binding, Competitive; Bromodeoxyuridine; Cyclopentanes; Cytosol; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; HeLa Cells; Humans; Mitochondria; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1997 |