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deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine

deoxyuridine has been researched along with 5-(2-chloroethyl)-2'-deoxyuridine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (53.33)	18.7374
1990's	3 (20.00)	18.2507
2000's	2 (13.33)	29.6817
2010's	1 (6.67)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Allen, TM; Knaus, EE; Kumar, R; Tovell, DR; Tyrrell, DL; Wiebe, LI; Xu, LH	1
Bernaerts, R; De Clercq, E; Merta, A; Rosenwirth, B	1
De Clercq, E; Griengl, H; Rosenwirth, B; Schwarz, W; Streicher, W; Wanek, E	2
De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B	1
De Clercq, E; Griengl, H; Rosenwirth, B; Wanek, E	1
De Clercq, E; Rosenwirth, B	1
Belloc, I; Bricaud, H; De Clercq, E; Desgranges, C; Drouillet, F; Razaka, G	1
Bernaerts, R; Breemersch, M; De Clercq, E; Dieltiens, M; Maudgal, PC; Van Eeckhoutte, L	1
Docherty, JJ; Wilber, BA	1
De Clercq, E; Huyghe, P; Maudgal, PC	1
Glowienke, S; Martus, HJ; Plappert-Helbig, U; Poetter-Locher, F; Racine, R; Staedtler, F; Suter, W	1
Martus, HJ; Staedtler, F; Suter, W	1
Dertinger, SD; Downing, R; Elhajouji, A; Martus, H; Vaskova, D	1
Hughes, C; Lewis, P; Warren, S; Waters, MD; Zhang, F	1

Reviews

1 review(s) available for deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine

Article	Year
Human genetic risk of treatment with antiviral nucleoside analog drugs that induce lethal mutagenesis: The special case of molnupiravir. Environmental and molecular mutagenesis, 2022, Volume: 63, Issue:1 Topics: Amides; Antiviral Agents; COVID-19 Drug Treatment; Cytidine; Deoxyuridine; DNA Damage; Genome, Human; Humans; Hydroxylamines; Mutagenesis; Nucleosides; Pyrazines; Ribavirin; SARS-CoV-2	2022

Other Studies

14 other study(ies) available for deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine

Article	Year
Synthesis and antiviral and cytotoxic activity of iodohydrin and iodomethoxy derivatives of 5-vinyl-2'-deoxyuridines, 2'-fluoro-2'-deoxyuridine, and uridine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Biological Transport; Cell Survival; Chemical Phenomena; Chemistry; Deoxyuridine; In Vitro Techniques; Leukemia L1210; Leukemia P388; Mice; Tumor Cells, Cultured; Uridine; Vinyl Compounds	1990
Mechanism of action of 5-(2-chloroethyl)-2'-deoxyuridine, a selective inhibitor of herpes simplex virus replication. Molecular pharmacology, 1990, Volume: 37, Issue:5 Topics: Animals; Antiviral Agents; Biotransformation; Deoxyuridine; DNA Replication; DNA-Directed DNA Polymerase; HeLa Cells; Humans; Simplexvirus; Vero Cells; Virus Replication	1990
In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil. Antiviral research, 1987, Volume: 7, Issue:5 Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; DNA, Viral; Female; Floxuridine; Guinea Pigs; Herpes Simplex; Mice; Mice, Hairless; RNA, Viral; Simplexvirus; Virus Replication	1987
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity. Journal of medicinal chemistry, 1988, Volume: 31, Issue:9 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells	1988
5-(2-Chloroethyl)-2'-deoxyuridine: a potent and selective inhibitor of herpes viruses in vitro and in vivo. Antiviral research, 1985, Volume: Suppl 1 Topics: Acyclovir; Animals; Antiviral Agents; Cell Line; Deoxyuridine; DNA, Viral; Herpes Simplex; Herpesviridae; Herpesvirus 3, Human; Mice; Mice, Hairless; RNA, Viral; Simplexvirus; Time Factors; Virus Replication	1985
Selective in vitro and in vivo activities of 5-(2-haloalkyl)pyrimidine nucleoside analogs, particularly 5-(2-chloroethyl)-2'-deoxyuridine, against herpes simplex virus. Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2 Topics: Animals; Cell Division; Cytopathogenic Effect, Viral; Deoxyuridine; Herpes Simplex; In Vitro Techniques; Mice; Microbial Sensitivity Tests; Neoplasms, Experimental; Nucleic Acids; Protein Biosynthesis; Pyrimidine Nucleosides; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus	1985
Deoxyribosyl exchange reactions leading to the in vivo generation and regeneration of the antiviral agents (E)-5-(2-bromovinyl)-2'-deoxyuridine, 5-ethyl-2'-deoxyuridine and 5-(2-chloroethyl)-2'-deoxyuridine. Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10 Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Bromouracil; Deoxyuridine; Half-Life; Humans; Male; Rabbits; Rats; Rats, Inbred Strains; Simplexvirus; Uracil	1986
2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity. Journal of medicinal chemistry, 1987, Volume: 30, Issue:7 Topics: Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Floxuridine; Simplexvirus; Structure-Activity Relationship	1987
Ocular penetration and efficacy of chloroethyldeoxyuridine against herpetic keratouveitis. Investigative ophthalmology & visual science, 1986, Volume: 27, Issue:10 Topics: Animals; Anterior Chamber; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Iritis; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits	1986
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine. The Journal of general virology, 1994, Volume: 75 ( Pt 7) Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine	1994
Efficacy of (S)-HPMPA against thymidine kinase-deficient herpes simplex virus-keratitis. Investigative ophthalmology & visual science, 1987, Volume: 28, Issue:2 Topics: Adenine; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Deoxyuridine; Herpesvirus 1, Human; Keratitis, Herpetic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Thymidine Kinase	1987
Induction of gene mutations by 5-(2-chloroethyl)-2'-deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue. Mutation research, 2004, Dec-21, Volume: 568, Issue:2 Topics: Animals; Antiviral Agents; Comet Assay; Deoxyuridine; DNA Repair; Female; Male; Mice; Micronucleus Tests; Mutation; Pregnancy; Rats; Salmonella; Skin Pigmentation	2004
Induction of A:T to G:C transition mutations by 5-(2-chloroethyl)-2'-deoxyuridine (CEDU), an antiviral pyrimidine nucleoside analogue, in the bone marrow of Muta Mouse. Mutation research, 2004, Dec-21, Volume: 568, Issue:2 Topics: Animals; Antiviral Agents; Base Composition; Base Sequence; Bone Marrow Cells; Deoxyuridine; DNA Mutational Analysis; DNA Primers; DNA Repair; Lac Operon; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Sequence Analysis, DNA	2004
Induction of in vivo Pig-a gene mutation but not micronuclei by 5-(2-chloroethyl)-2'-deoxyuridine, an antiviral pyrimidine nucleoside analogue. Mutagenesis, 2018, 12-31, Volume: 33, Issue:5-6 Topics: Animals; Antiviral Agents; Deoxyuridine; DNA Damage; Erythrocytes; Flow Cytometry; Membrane Proteins; Mice; Micronucleus, Germline; Mutagenesis; Mutagens; Mutation; Pyrimidine Nucleosides; Rats; Reticulocytes	2018