Page last updated: 2024-08-23

deoxynivalenol and interleukin-8

deoxynivalenol has been researched along with interleukin-8 in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (37.04)29.6817
2010's15 (55.56)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Pestka, JJ; Sugita-Konishi, Y1
Hetland, G; Instanes, C1
Gray, JS; Islam, Z; Pestka, JJ1
Gray, JS; Pestka, JJ1
Lee, SH; Moon, Y; Yang, H1
Boyron, M; Caporiccio, B; Fantini, J; Maresca, M; Yahi, N; Younès-Sakr, L1
Larondelle, Y; Romier, B; Schneider, YJ; Van De Walle, J1
Moon, Y; Park, SH; Yang, H1
Bae, HK; Gray, JS; Lau, AS; Li, JC; Pestka, JJ1
Choi, HJ; Moon, Y; Park, SH; Yang, H1
Bae, H; Gray, JS; Kim, J; Li, M; Pestka, JJ; Vines, L1
During, A; Larondelle, Y; Piront, N; Schneider, YJ; Toussaint, O; Van De Walle, J1
Choi, HJ; Do, KH; Kim, J; Moon, Y; Park, SH; Yang, H1
Gauthier, T; Laffitte, J; Mori, Y; Oswald, IP; Saeedikouzehkonani, N; Taranu, I; Waché, Y1
Furusawa, H; Hirano, S; Kadota, T; Kamata, Y; Sugita-Konishi, Y; Tajima, O1
Liu, J; Pei, R; Simmons, SO1
Akbari, P; Alizadeh, A; Braber, S; Fink-Gremmels, J; Garssen, J; Kraneveld, AD; Schoterman, MH; Verheijden, KA1
Caloni, F; Camatini, M; Capasso, L; Gualtieri, M; Longhin, E1
Dänicke, S; Diesing, AK; Kahlert, S; Kluess, JW; Kröber, A; Rothkötter, HJ; Wimmers, K1
Akbari, P; Braber, S; Difilippo, E; Fink-Gremmels, J; Garssen, J; Schols, HA; Schoterman, MHC; Willems, RHAM1
Kim, D; Kim, J; Moon, Y; Park, SH1
Akbari, P; Alizadeh, A; Braber, S; Fink-Gremmels, J; Garssen, J; Kraneveld, A1
Ciarlo, E; Ferreira Lopes, S; Niculita-Hirzel, H; Roger, T; Savova-Bianchi, D; Vacher, G1
Du, Z; Kim, J; Kim, KH; Moon, Y1
Amiri, KMA; Co, VA; El-Nezami, H; Turner, PC; Wan, MLY; Wang, MF1
Abeln, H; Abia, W; Beisl, J; Del Favero, G; Ehling-Schulz, M; Ezekiel, CN; Marko, D; Pahlke, G; Sulyok, M; Varga, E; Warth, B1
Höher, T; Lienhart, L; Pirklbauer, S; Pöschl, F; Ressler, M; Riederer, M; Wolinski, H1

Other Studies

27 other study(ies) available for deoxynivalenol and interleukin-8

ArticleYear
Differential upregulation of TNF-alpha, IL-6, and IL-8 production by deoxynivalenol (vomitoxin) and other 8-ketotrichothecenes in a human macrophage model.
    Journal of toxicology and environmental health. Part A, 2001, Dec-21, Volume: 64, Issue:8

    Topics: Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-6; Interleukin-8; Macrophages; Models, Biological; Mycotoxins; Trichothecenes; Tumor Necrosis Factor-alpha; Up-Regulation

2001
Deoxynivalenol (DON) is toxic to human colonic, lung and monocytic cell lines, but does not increase the IgE response in a mouse model for allergy.
    Toxicology, 2004, Nov-01, Volume: 204, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Caco-2 Cells; Cell Division; Cell Line, Tumor; Cell Survival; Colon; Female; Humans; Hypersensitivity; Immunoglobulin E; Interleukin-8; Lung; Lymph Nodes; Mice; Mice, Inbred BALB C; Monocytes; Protein Biosynthesis; Trichothecenes; U937 Cells

2004
p38 Mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes.
    Toxicology and applied pharmacology, 2006, Jun-15, Volume: 213, Issue:3

    Topics: Anisomycin; Emetine; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Monocytes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Trichothecenes; U937 Cells

2006
Transcriptional regulation of deoxynivalenol-induced IL-8 expression in human monocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 99, Issue:2

    Topics: CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Gene Expression Regulation; Humans; Interleukin-8; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; RNA Stability; Transcription Factor RelA; Transcription, Genetic; Trichothecenes

2007
Modulation of early growth response gene 1 and interleukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells.
    Biochemical and biophysical research communications, 2007, Oct-19, Volume: 362, Issue:2

    Topics: Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Epithelial Cells; Humans; Interleukin-8; Intestinal Mucosa; Intestines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trichothecenes

2007
Both direct and indirect effects account for the pro-inflammatory activity of enteropathogenic mycotoxins on the human intestinal epithelium: stimulation of interleukin-8 secretion, potentiation of interleukin-1beta effect and increase in the transepithel
    Toxicology and applied pharmacology, 2008, Apr-01, Volume: 228, Issue:1

    Topics: Bacteria; Caco-2 Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-8; Intestinal Mucosa; Mycotoxins; NF-kappa B; Ochratoxins; p38 Mitogen-Activated Protein Kinases; Patulin; Permeability; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Trichothecenes

2008
Influence of deoxynivalenol on NF-kappaB activation and IL-8 secretion in human intestinal Caco-2 cells.
    Toxicology letters, 2008, Apr-01, Volume: 177, Issue:3

    Topics: Caco-2 Cells; Dose-Response Relationship, Drug; Enteritis; Humans; I-kappa B Kinase; Interleukin-1beta; Interleukin-8; NF-kappa B; Phosphorylation; Trichothecenes; Tumor Necrosis Factor-alpha

2008
Hypo-responsiveness of interleukin-8 production in human embryonic epithelial intestine 407 cells independent of NF-kappaB pathway: new lessons from endotoxin and ribotoxic deoxynivalenol.
    Toxicology and applied pharmacology, 2008, Aug-15, Volume: 231, Issue:1

    Topics: Blotting, Western; Cell Line; Cell Survival; Early Growth Response Protein 1; Endotoxins; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indicators and Reagents; Interleukin-8; Intestinal Mucosa; Luciferases; NF-kappa B; Plasmids; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 4; Transfection; Trichothecenes

2008
Double-stranded RNA-activated protein kinase mediates induction of interleukin-8 expression by deoxynivalenol, Shiga toxin 1, and ricin in monocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 105, Issue:2

    Topics: Dose-Response Relationship, Drug; eIF-2 Kinase; Humans; Interleukin-8; Monocytes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Ricin; RNA, Messenger; Shiga Toxin 1; Signal Transduction; Transcription Factor RelA; Transfection; Trichothecenes; U937 Cells; Up-Regulation

2008
HuR/ELAVL1 RNA binding protein modulates interleukin-8 induction by muco-active ribotoxin deoxynivalenol.
    Toxicology and applied pharmacology, 2009, Oct-01, Volume: 240, Issue:1

    Topics: Antigens, Surface; Cell Line; ELAV Proteins; ELAV-Like Protein 1; Humans; Interleukin-8; Intestinal Mucosa; Protein Transport; Ribosomes; RNA Stability; RNA-Binding Proteins; Trichothecenes

2009
Hematopoietic cell kinase associates with the 40S ribosomal subunit and mediates the ribotoxic stress response to deoxynivalenol in mononuclear phagocytes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:2

    Topics: Animals; eIF-2 Kinase; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Interleukin-8; Macrophages, Peritoneal; Mice; Mononuclear Phagocyte System; p38 Mitogen-Activated Protein Kinases; Phagocytes; Proto-Oncogene Proteins c-hck; Pyrimidines; Ribosomal Proteins; Ribosome Subunits, Small, Eukaryotic; Trichothecenes; U937 Cells

2010
Physio-pathological parameters affect the activation of inflammatory pathways by deoxynivalenol in Caco-2 cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:7

    Topics: Caco-2 Cells; Cell Differentiation; Cell Proliferation; Dinoprostone; Dose-Response Relationship, Drug; Humans; Inflammation; Inflammation Mediators; Interleukin-8; Intestinal Mucosa; Time Factors; Trichothecenes

2010
Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Nov-01, Volume: 185, Issue:9

    Topics: Anisomycin; Antigens, Surface; Blotting, Western; Cell Line; ELAV Proteins; ELAV-Like Protein 1; Enzyme-Linked Immunosorbent Assay; Gene Expression; Gene Expression Regulation; Humans; Immunity, Mucosal; Interleukin-8; Intestinal Mucosa; Microscopy, Confocal; PPAR gamma; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Transcription Factor CHOP; Transfection; Trichothecenes

2010
Deoxynivalenol impairs the immune functions of neutrophils.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:6

    Topics: Animals; Caspase 3; Cell Death; Chemotaxis; Enzyme Activation; Escherichia coli; Hydrogen Peroxide; Interleukin-8; Lipopolysaccharides; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinase 3; Mycotoxins; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Swine; Trichothecenes

2013
Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenol on intestinal transport and IL-8 secretion in the human cell line Caco-2.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:6

    Topics: Biological Transport; Caco-2 Cells; Cell Survival; Gene Expression Profiling; Humans; Interleukin-8; Intestinal Absorption; Intestinal Mucosa; Oligonucleotide Array Sequence Analysis; Trichothecenes

2013
Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells.
    Journal of toxicology and environmental health. Part A, 2014, Volume: 77, Issue:19

    Topics: CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Interleukin-8; Lentivirus; Luciferases; Monocytes; NF-kappa B; Ochratoxins; Promoter Regions, Genetic; Signal Transduction; Trichothecenes; Tumor Necrosis Factor-alpha; Up-Regulation

2014
Galacto-oligosaccharides Protect the Intestinal Barrier by Maintaining the Tight Junction Network and Modulating the Inflammatory Responses after a Challenge with the Mycotoxin Deoxynivalenol in Human Caco-2 Cell Monolayers and B6C3F1 Mice.
    The Journal of nutrition, 2015, Volume: 145, Issue:7

    Topics: Animals; Caco-2 Cells; Claudin-3; Epithelial Cells; Gene Expression Regulation; Humans; Inflammatory Bowel Diseases; Interleukin-8; Intestinal Mucosa; Male; Mice; Oligosaccharides; Permeability; Tight Junctions; Trichothecenes

2015
Synergistic inflammatory effect of PM10 with mycotoxin deoxynivalenol on human lung epithelial cells.
    Toxicon : official journal of the International Society on Toxinology, 2015, Sep-15, Volume: 104

    Topics: Air Pollutants; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Humans; Interleukin-6; Interleukin-8; Lung; Particulate Matter; Seasons; Trichothecenes

2015
Deoxynivalenol, but not E. coli lipopolysaccharide, changes the response pattern of intestinal porcine epithelial cells (IPEC-J2) according to its route of application.
    Toxicology letters, 2015, Dec-15, Volume: 239, Issue:3

    Topics: Actins; Animals; Cell Count; Cells, Cultured; Epithelial Cells; Escherichia coli; Interleukin-8; Intestines; Lipopolysaccharides; Swine; Tight Junctions; Trichothecenes; Up-Regulation; Zonula Occludens-1 Protein

2015
Characterizing microbiota-independent effects of oligosaccharides on intestinal epithelial cells: insight into the role of structure and size : Structure-activity relationships of non-digestible oligosaccharides.
    European journal of nutrition, 2017, Volume: 56, Issue:5

    Topics: Caco-2 Cells; Epithelial Cells; Gastrointestinal Microbiome; Humans; Interleukin-8; Intestines; Inulin; Oligosaccharides; Structure-Activity Relationship; Trichothecenes

2017
Mycotoxin detoxifiers attenuate deoxynivalenol-induced pro-inflammatory barrier insult in porcine enterocytes as an in vitro evaluation model of feed mycotoxin reduction.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 38

    Topics: Animal Feed; Animals; Bentonite; Cell Line; Cell Wall; Chemokine CCL2; Diatomaceous Earth; Enterocytes; Food Contamination; Interleukin-8; Swine; Trichothecenes; Yeasts

2017
Deoxynivalenol and Its Modified Forms: Are There Major Differences?
    Toxins, 2016, 11-16, Volume: 8, Issue:11

    Topics: Caco-2 Cells; Cell Survival; Epithelial Cells; Humans; Interleukin-8; L-Lactate Dehydrogenase; Oligosaccharides; Trichothecenes

2016
Primary and Immortalized Human Respiratory Cells Display Different Patterns of Cytotoxicity and Cytokine Release upon Exposure to Deoxynivalenol, Nivalenol and Fusarenon-X.
    Toxins, 2017, 10-25, Volume: 9, Issue:11

    Topics: Cell Line; Cell Survival; Epithelial Cells; Humans; Interleukin-6; Interleukin-8; Respiratory System; Trichothecenes

2017
Fungal Deoxynivalenol-Induced Enterocyte Distress Is Attenuated by Adulterated Adlay:
    Frontiers in immunology, 2018, Volume: 9

    Topics: Animals; Cell Line; Cell Proliferation; Chemokines; Diet; ELAV-Like Protein 1; Enterocytes; HT29 Cells; Humans; Inflammation; Interleukin-8; Plant Extracts; Poaceae; Protein Kinase C; rhoA GTP-Binding Protein; Signal Transduction; Swine; Trichothecenes

2018
Schisandrin A protects intestinal epithelial cells from deoxynivalenol-induced cytotoxicity, oxidative damage and inflammation.
    Scientific reports, 2019, 12-16, Volume: 9, Issue:1

    Topics: Catalase; Cell Cycle Checkpoints; Cell Death; Cell Nucleus; Cell Survival; Cyclooctanes; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Enterocytes; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; HT29 Cells; Humans; Inflammation; Inflammation Mediators; Interleukin-8; Lignans; Lipid Peroxidation; MAP Kinase Signaling System; Models, Biological; NF-E2-Related Factor 2; NF-kappa B; Nitrites; Oxidative Stress; Polycyclic Compounds; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Trichothecenes

2019
Combinatory effects of cereulide and deoxynivalenol on in vitro cell viability and inflammation of human Caco-2 cells.
    Archives of toxicology, 2020, Volume: 94, Issue:3

    Topics: Caco-2 Cells; Cell Survival; Depsipeptides; Diet; Emetics; Food Contamination; Humans; Inflammation; Interleukin-1beta; Interleukin-8; Intestinal Mucosa; Intestines; Mycotoxins; Trichothecenes

2020
Dose and route dependent effects of the mycotoxin deoxynivalenol in a 3D gut-on-a-chip model with flow.
    Toxicology in vitro : an international journal published in association with BIBRA, 2023, Volume: 88

    Topics: Animals; Caco-2 Cells; Humans; Interleukin-8; Intestinal Mucosa; Lab-On-A-Chip Devices; Mycotoxins

2023