deoxyguanosine-triphosphate and bis(3--5-)-cyclic-diguanylic-acid

deoxyguanosine-triphosphate has been researched along with bis(3--5-)-cyclic-diguanylic-acid* in 1 studies

Other Studies

1 other study(ies) available for deoxyguanosine-triphosphate and bis(3--5-)-cyclic-diguanylic-acid

ArticleYear
Enzymatic synthesis of 2'-ara and 2'-deoxy analogues of c-di-GMP.
    Nucleosides, nucleotides & nucleic acids, 2015, Volume: 34, Issue:6

    The substrate specificity of recombinant full-length diguanylate cyclase (DGC) of Thermotoga maritima with mutant allosteric site was investigated. It has been originally shown that the enzyme could use GTP closest analogues - 2'-deoxyguanosine-5'-triphosphate (dGTP) and 9-β-D-arabinofuranosyl-guanine-5'-triphosphate (araGTP) as the substrates. The first demonstrations of an enzymatic synthesis of bis-(3'-5')-cyclic dimeric deoxyguanosine monophosphate (c-di-dGMP) and the previously unknown bis-(3'-5')-cyclic dimeric araguanosine monophosphate (c-di-araGMP) using DGC of T. maritima in the form of inclusion bodies have been provided.

    Topics: Arabinonucleotides; Bacterial Proteins; Cyclic GMP; Deoxyguanine Nucleotides; Escherichia coli Proteins; Guanosine Triphosphate; Phosphorus-Oxygen Lyases; Thermotoga maritima

2015