Page last updated: 2024-09-02

deoxyglucose and lovastatin

deoxyglucose has been researched along with lovastatin in 3 studies

Compound Research Comparison

Studies
(deoxyglucose)
Trials
(deoxyglucose)
Recent Studies (post-2010)
(deoxyglucose)
Studies
(lovastatin)
Trials
(lovastatin)
Recent Studies (post-2010) (lovastatin)
11,4261711,3754,828698873

Protein Interaction Comparison

ProteinTaxonomydeoxyglucose (IC50)lovastatin (IC50)
Chain A, Antigen Cd11a (p180)Homo sapiens (human)2.4
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)0.0261
Integrin beta-2Homo sapiens (human)3.09
Intercellular adhesion molecule 1Homo sapiens (human)3.78
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)8.753
ATP-dependent translocase ABCB1Homo sapiens (human)10
Neutrophil elastaseHomo sapiens (human)0.027
Insulin receptor Rattus norvegicus (Norway rat)0.02
Integrin alpha-LHomo sapiens (human)3.09
Sodium-dependent noradrenaline transporter Homo sapiens (human)8.753
Prostaglandin G/H synthase 2Homo sapiens (human)0.02
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)0.0529

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Hanson, SY; Johnson, AC; Zager, RA1
Chen, JH; Du, JJ; Huang, JJ; Huang, XM; Huang, Z; Lin, QY; Lin, WJ; Long, Z; Ma, WZ; Qin, X; Shen, YF; Yang, Y; Zhang, N; Zheng, BW; Zhong, FF1
Asperti, M; Bernardi, S; Cassandri, M; Codenotti, S; Fanzani, A; Gastaldello, S; Giacomini, A; Mandracchia, D; Marampon, F; Mignani, L; Mitola, S; Monti, E; Parolini, S; Poli, M; Rezzola, S; Rota, R; Russo, D; Tabellini, G; Tomasini, D; Triggiani, L; Vezzoli, M; Zizioli, D1

Other Studies

3 other study(ies) available for deoxyglucose and lovastatin

ArticleYear
Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:6

    Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Anticholesteremic Agents; Antimetabolites; Antimycin A; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; CD36 Antigens; Cell Line, Transformed; Cholesterol; Deoxyglucose; Glycolysis; Humans; Hydroxymethylglutaryl CoA Reductases; Kidney Tubules, Proximal; Lovastatin; Membrane Proteins; Mitochondria; Protein Prenylation; ras Proteins; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Scavenger; rho GTP-Binding Proteins; Rotenone; Scavenger Receptors, Class B; Uncoupling Agents

2003
Autophagy inhibitors increase the susceptibility of KRAS-mutant human colorectal cancer cells to a combined treatment of 2-deoxy-D-glucose and lovastatin.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:11

    Topics: Animals; Antimetabolites; Autophagy; Cell Survival; Chloroquine; Colorectal Neoplasms; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HCT116 Cells; HEK293 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Proto-Oncogene Proteins p21(ras); Xenograft Model Antitumor Assays

2021
Hyperactive Akt1 Signaling Increases Tumor Progression and DNA Repair in Embryonal Rhabdomyosarcoma RD Line and Confers Susceptibility to Glycolysis and Mevalonate Pathway Inhibitors.
    Cells, 2022, 09-14, Volume: 11, Issue:18

    Topics: Animals; Child; Deoxyglucose; DNA Repair; DNA-Activated Protein Kinase; Doxorubicin; Glucose; Glycolysis; Hexokinase; Histones; Humans; Ki-67 Antigen; Lovastatin; Mevalonic Acid; MTOR Inhibitors; Oxidoreductases; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Proto-Oncogene Proteins c-akt; Rhabdomyosarcoma, Embryonal; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; TOR Serine-Threonine Kinases; Zebrafish

2022