deoxyepinephrine has been researched along with alpha-methyldopamine in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (44.44) | 18.7374 |
| 1990's | 8 (17.78) | 18.2507 |
| 2000's | 8 (17.78) | 29.6817 |
| 2010's | 9 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castagnoli, N; Chavdarian, CG; Hundley, HK; Karashima, D | 1 |
| Axelrod, J; Hoffman, AR; Sastry, BV | 1 |
| Aisenbrey, G; Catanzarite, V; Quirk, JG | 1 |
| Hsu, FL; Yeh, SY | 1 |
| McCann, UD; Ricaurte, GA | 1 |
| Ahn, CH; Feller, DR; Miller, DD; Schotzinger, RL; Shams, G | 1 |
| Fujita, T; Sato, Y | 1 |
| Campbell, NR; Sundaram, RS; Van Loon, J; Weinshilboum, RM; Werness, PG | 1 |
| Carty, SE; Johnson, RG; Pallant, A; Scarpa, A; Vaughan, T | 1 |
| Chuang, LW; Karoum, F; Shelton, RC; Wyatt, RJ | 1 |
| Gouw, MA; Timmermans, PB; van Zwieten, PA; Wilffert, B | 1 |
| Baer, PN; Goldenhar, M | 1 |
| Maemura, S; Niwa, M; Ozaki, M | 1 |
| Goldberg, MR; Morgan, EL; Ruffolo, RR | 1 |
| Linares Rodríguez, A; Recarte Alvarez, J; Rodrigo Sáez, L; Valerdiz Casasola, S | 1 |
| Handa, S; Nakamura, Y; Nakazawa, H; Ohnishi, S; Okamoto, S; Toyama, K | 1 |
| Cuparencu, B; Sandor, V | 1 |
| Dougan, DF; Duffield, AM; Duffield, PH; Wade, DN | 1 |
| Mwaluko, G; Weinshilboum, R | 1 |
| Bretagne, Y; Foucher, M; Habibi, B; Muller, A | 1 |
| Bauce, L; Cooper, KE; Thornhill, JA; Veale, WL | 1 |
| Barboni, E; D'Erme, M; Fiori, A; Minelli, A; Rosei, MA; Turano, C; Voltattorni, CB | 1 |
| Cass, WA; Flach, KA; Gerhardt, GA; Zahniser, NR | 1 |
| Bourquin, D; Bracher, K; Brenneisen, R; Helmlin, HJ; Vonlanthen, D | 1 |
| Ensslin, HK; Kovar, KA; Maurer, HH | 1 |
| Lau, SS; Miller, RT; Monks, TJ | 1 |
| DAY, MD; RAND, MJ | 1 |
| GRANA, E; LAMANNA, A; PRATESI, P | 1 |
| Easton, N; Fry, J; Kingston, S; Marsden, CA; O'Shea, E; Watkins, A | 1 |
| Amado, F; Bastos, ML; Borges, F; Carvalho, F; Carvalho, M; Fernandes, E; Milhazes, N; Monks, TJ; Remião, F | 1 |
| Amado, F; Bastos, ML; Borges, F; Carvalho, F; Carvalho, M; Fernandes, E; Gonçalves, MJ; Milhazes, N; Monteiro, Mdo C; Remião, F; Seabra, V | 1 |
| Bastos, ML; Borges, F; Carvalho, F; Carvalho, M; Fernandes, E; Milhazes, N; Remião, F | 1 |
| Bastos, Mde L; Boer, Dd; Branco, PS; Brulport, M; Carmo, H; Carvalho, F; Doehmer, J; Ferreira, LM; Hengstler, JG; Hermes, M; Krebsfaenger, N; Oesch, F; Remião, F; Schön, MR; Silva, R | 1 |
| Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Dirnagl, U; Fernandes, E; Ferreira, LM; Lobo, AM; Macedo, C; Meisel, A; Remião, F | 1 |
| Banks, ML; Czoty, PW; Kisor, DF; Nader, MA; Nichols, DE; Sprague, JE | 1 |
| Carvalho, F; Lucchesi, PA; Shenouda, SK; Varner, KJ | 1 |
| Abad, S; Camarasa, J; Escubedo, E; Pubill, D; Torres, I | 1 |
| Barbosa, DJ; Branco, PS; Capela, JP; Carvalho, F; de Lourdes Bastos, M; Duarte, JA; Fernandes, E; Ferreira, LM; Oliveira, JM; Silva, R; Siopa, F | 1 |
| Garcia-Cánovas, F; Garcia-Molina, F; Muñoz-Muñoz, JL; Rodríguez-López, JN; Tudela, J; Varon, R | 1 |
| Largeron, M; Martinez, CM; Neudörffer, A | 1 |
| Carmo, H; Carvalho, F; da Silva, DD; Silva, E | 1 |
| Barbosa, DJ; Bastos, Mde L; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R; Vilas-Boas, V | 1 |
| Barbosa, DJ; Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R | 1 |
| Maurer, HH; Meyer, MR; Richter, LH | 1 |
| Almeida, B; Baixeras, E; de la Torre, R; Decara, JM; Gavito, AL; Joglar, J; Pavón, FJ; Rivera, P; Rodríguez de Fonseca, F; Romero-Cuevas, M; Serrano, A; Suárez, J; Vázquez, M | 1 |
2 review(s) available for deoxyepinephrine and alpha-methyldopamine
| Article | Year |
|---|---|
[High performance liquid chromatography-electrochemical detection (LC-EC) and its clinical use, with special reference to the detection of biogenic amines].
Topics: Animals; Biogenic Amines; Catecholamines; Chromatography, High Pressure Liquid; Deoxyepinephrine; Humans; Hypertension; Rats; Rats, Inbred Strains; Serotonin | 1984 |
[Hepatitis caused by drugs. 5].
Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Deoxyepinephrine; Erythromycin; Gold; Humans; Hypoglycemic Agents; Oxacillin; Oxyphenisatin Acetate; Perhexiline; Phenylbutazone; Prognosis; Propylthiouracil | 1982 |
2 trial(s) available for deoxyepinephrine and alpha-methyldopamine
| Article | Year |
|---|---|
Sulfate and methyldopa metabolism: metabolite patterns and platelet phenol sulfotransferase activity.
Topics: Absorption; Acetaminophen; Administration, Oral; Adult; Arylsulfotransferase; Carbon Radioisotopes; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Deoxyepinephrine; Drug Interactions; Female; Humans; Male; Methyldopa; Random Allocation; Sulfates; Sulfurtransferases | 1985 |
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Deoxyepinephrine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Ion Exchange Resins; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards | 1996 |
41 other study(ies) available for deoxyepinephrine and alpha-methyldopamine
| Article | Year |
|---|---|
Oxidative and cardiovascular studies on natural and synthetic catecholamines.
Topics: Animals; Blood Pressure; Catecholamines; Cyclization; Dose-Response Relationship, Drug; Electrochemistry; Heart Rate; Male; Oxidation-Reduction; Rats; Structure-Activity Relationship | 1978 |
Formation of alpha-methyldopamine ("Catecholamphetamine") from p-hydroxyamphetamine by rat brain microsomes.
Topics: Amphetamines; Animals; Brain; Catechol O-Methyltransferase; Catechols; Deoxyepinephrine; Dopamine; In Vitro Techniques; Male; Microsomes; p-Hydroxyamphetamine; Rats | 1979 |
How do perinatologists manage preeclampsia?
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure Determination; Data Collection; Delivery, Obstetric; Deoxyepinephrine; Female; Humans; Hydralazine; Magnesium Sulfate; Perinatology; Pre-Eclampsia; Pregnancy; Societies, Medical | 1991 |
The neurochemical and stimulatory effects of putative metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Central Nervous System Stimulants; Cerebral Cortex; Deoxyepinephrine; Dopamine; Epinephrine; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nordefrin; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Major metabolites of (+/-)3,4-methylenedioxyamphetamine (MDA) do not mediate its toxic effects on brain serotonin neurons.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Cerebral Cortex; Cerebral Ventricles; Corpus Striatum; Deoxyepinephrine; Dopamine; Functional Laterality; Hippocampus; Injections, Intraventricular; Male; Neurons; Organ Specificity; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Stereostructure activity relationships of catecholamines on human platelet function.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Catecholamines; Clonidine; Deoxyepinephrine; Dopamine; Epinephrine; Humans; Isomerism; Isoproterenol; Nordefrin; Norepinephrine; Phentolamine; Platelet Aggregation; Platelet Aggregation Inhibitors; Structure-Activity Relationship | 1990 |
[Drug resistance and withdrawal syndrome--study on receptors].
Topics: Animals; Clonidine; Deoxyepinephrine; Drug Resistance; Humans; Hypertension; Receptors, Opioid; Substance Withdrawal Syndrome | 1985 |
Amine transport into chromaffin ghosts. Kinetic measurements of net uptake of biologically and pharmacologically relevant amines using an on-line amperometric technique.
Topics: Adrenal Medulla; Amines; Animals; Biological Transport; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Deoxyepinephrine; Electrochemistry; In Vitro Techniques; Kinetics; Nordefrin; Serotonin | 1985 |
Metabolism of carbidopa to alpha-methyldopamine and alpha-methylnorepinephrine in rats.
Topics: Administration, Oral; Animals; Biotransformation; Carbidopa; Deoxyepinephrine; Dopamine; Gas Chromatography-Mass Spectrometry; Hypothalamus; Male; Nordefrin; Norepinephrine; Rats; Rats, Inbred Strains; Septal Nuclei | 1985 |
Cardiovascular effects of dopamine and some methylated and fluorinated derivatives in pithed normotensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Cardiovascular System; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Heart Rate; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1983 |
The concurrent presence of an oral lichenoid drug reaction and an oral lichen planus.
Topics: Deoxyepinephrine; Dopamine; Drug Eruptions; Humans; Lichen Planus; Male; Middle Aged; Mouth Diseases; Stomatitis | 1983 |
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
Topics: Animals; Blood Pressure; Decerebrate State; Deoxyepinephrine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Male; Nordefrin; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Reserpine; Yohimbine | 1984 |
[Case of pure red cell aplasia due to cell-mediated suppression of erythropoiesis associated with Aldomet administration].
Topics: Adult; Anemia, Aplastic; Deoxyepinephrine; Dopamine; Erythropoiesis; Female; Humans | 1983 |
Effects of alpha-methylnoradrenaline and alpha-methyldopamine in reserpine-induced ulcers in rats.
Topics: Animals; Anti-Ulcer Agents; Deoxyepinephrine; Dopamine; Male; Nordefrin; Norepinephrine; Rats; Reserpine; Stomach Ulcer | 1981 |
Absence of alpha-methyldopamine in rat striatum after chronic administration of d-amphetamine.
Topics: alpha-Methyltyrosine; Animals; Chromatography, Gas; Corpus Striatum; Decarboxylation; Deoxyepinephrine; Dextroamphetamine; Dopamine; Male; Methyldopa; Methyltyrosines; Nordefrin; p-Hydroxyamphetamine; Rats; Time Factors | 1982 |
alpha-Methyldopa, alpha-methyldopamine an alpha-methylnoradrenaline: substrates for the thermolabile form of human platelet phenol sulphotransferase.
Topics: Arylsulfotransferase; Blood Platelets; Deoxyepinephrine; Dopamine; Hot Temperature; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Methyldopa; Nordefrin; Norepinephrine; Sulfurtransferases | 1982 |
[Asymptomatic autoimmune hemolysis linked to alpha-methyldopa. Importance of the study of erythrocyte survival in vivo].
Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Deoxyepinephrine; Dopamine; Erythrocyte Aging; Erythrocytes; Humans; Male; Middle Aged | 1982 |
A radioenzymatic assay for femtomole determination of catecholamines using alpha-methyldopamine as an internal standard.
Topics: Animals; Catechol O-Methyltransferase; Deoxyepinephrine; Dopamine; Epinephrine; Guinea Pigs; Humans; Microchemistry; Norepinephrine; Rabbits; Retina; Sheep | 1980 |
An abnormal reaction occurring in the presence of L-aromatic aminoacid decarboxylase.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Deoxyepinephrine; Guinea Pigs; Kidney; Kinetics; Methyldopa; Oxidation-Reduction; Pyridoxal Phosphate; Swine | 1981 |
Clearance of exogenous dopamine in rat dorsal striatum and nucleus accumbens: role of metabolism and effects of locally applied uptake inhibitors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechol O-Methyltransferase; Cocaine; Corpus Striatum; Deoxyepinephrine; Dopamine; Electrochemistry; Kinetics; Male; Microinjections; Nomifensine; Nucleus Accumbens; Oxidopamine; Prosencephalon; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Toxicological detection of the designer drug 3,4-methylenedioxyethylamphetamine (MDE, "Eve") and its metabolites in urine by gas chromatography-mass spectrometry and fluorescence polarization immunoassay.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Amphetamines; Deoxyepinephrine; Designer Drugs; Dopamine; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Time Factors | 1996 |
2,5-Bis-(glutathion-S-yl)-alpha-methyldopamine, a putative metabolite of (+/-)-3,4-methylenedioxyamphetamine, decreases brain serotonin concentrations.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Brain; Cerebral Cortex; Corpus Striatum; Deoxyepinephrine; Depression, Chemical; Glutathione; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents | 1997 |
SOME OBSERVATIONS ON THE PHARMACOLOGY OF ALPHA-METHYLDOPA.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carotid Sinus; Cats; Deoxyepinephrine; Dihydroxyphenylalanine; Dogs; Dopamine; Guinea Pigs; Humans; Ileum; Lagomorpha; Male; Methyldopa; Nictitating Membrane; Nordefrin; Norepinephrine; Pharmacology; Pressoreceptors; Rabbits; Rats; Research; Reserpine; Spleen; Sympathetic Nervous System; Tyramine; Vas Deferens | 1964 |
[DERIVATIVES OF PHENYLISOPROPYLAMINE. PREPARATION AND CONFIGURATION OF OPTICALLY ACTIVE 3,4-DIHYDROXYAMPHETAMINES].
Topics: Amphetamine; Amphetamines; Chemistry, Pharmaceutical; Deoxyepinephrine; Pharmacy; Research | 1964 |
Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Cytochrome P-450 CYP2D6; Deoxyepinephrine; Female; Glutathione; Humans; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2003 |
Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Biotransformation; Cell Survival; Cells, Cultured; Deoxyepinephrine; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hallucinogens; Hepatocytes; Lipid Peroxidation; Male; Rats; Rats, Wistar | 2004 |
Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
Topics: 3,4-Methylenedioxyamphetamine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Survival; Cells, Cultured; Deoxyepinephrine; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Metabolism; Myocytes, Cardiac; Rats; Serotonin Agents; Time Factors | 2004 |
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Cell Separation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyepinephrine; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hallucinogens; Hepatocytes; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Spectrophotometry, Ultraviolet | 2004 |
Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Topics: Alleles; Animals; Catalysis; Cell Line; Cricetinae; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dose-Response Relationship, Drug; Hallucinogens; Models, Biological; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Polymorphism, Genetic | 2006 |
Neurotoxicity mechanisms of thioether ecstasy metabolites.
Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Adenosine Triphosphate; Animals; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Deoxyepinephrine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Free Radical Scavengers; Glutathione; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Wistar; Temperature; Time Factors | 2007 |
Ambient temperature effects on 3,4-methylenedioxymethamphetamine-induced thermodysregulation and pharmacokinetics in male monkeys.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Body Temperature; Deoxyepinephrine; Fever; Hallucinogens; Macaca fascicularis; Male; Serotonin Agents; Temperature | 2007 |
Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium Signaling; Cells, Cultured; Deoxyepinephrine; Dose-Response Relationship, Drug; Glutathione; Heart Ventricles; Male; Myocardial Contraction; Myocytes, Cardiac; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors | 2009 |
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Paroxetine; PC12 Cells; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes | 2011 |
Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Animals; Antioxidants; Brain; Deoxyepinephrine; Dopamine; Glutathione; Hallucinogens; Hydrogen Peroxide; Levodopa; Male; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Protein Carbonylation; Serotonin; Synaptosomes | 2012 |
Kinetic cooperativity of tyrosinase. A general mechanism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Caffeic Acids; Catechols; Cresols; Deoxyepinephrine; Dopamine; Models, Chemical; Monophenol Monooxygenase; Phenols; Phenylacetates; Phenylpropionates; Quinones; Substrate Specificity | 2011 |
A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ("ecstasy") from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.
Topics: Biomimetic Materials; Deoxyepinephrine; Molecular Conformation; N-Methyl-3,4-methylenedioxyamphetamine; Optical Phenomena; Stereoisomerism | 2012 |
Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations.
Topics: 3,4-Methylenedioxyamphetamine; Biotransformation; Cell Survival; Chemical and Drug Induced Liver Injury; Deoxyepinephrine; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nonlinear Dynamics; Risk Assessment; Temperature; Time Factors | 2014 |
The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.
Topics: Acetylcysteine; Calcium; Caspase 3; Cell Differentiation; Cell Line; Deoxyepinephrine; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Glutathione; Humans; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Reactive Oxygen Species | 2014 |
"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Caspase 3; Cell Death; Cell Differentiation; Cell Line; Deoxyepinephrine; Fever; Glutathione; Humans; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Temperature | 2014 |
Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dinitrochlorobenzene; Enzyme Assays; Female; Glutathione; Glutathione Transferase; Humans; Isomerism; N-Methyl-3,4-methylenedioxyamphetamine; Placenta; Pregnancy; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry | 2014 |
Treatment with a novel oleic-acid-dihydroxyamphetamine conjugation ameliorates non-alcoholic fatty liver disease in obese Zucker rats.
Topics: Adiposity; Animals; Body Weight; Deoxyepinephrine; Ether-A-Go-Go Potassium Channels; Feeding Behavior; Genotype; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Oleic Acid; PPAR alpha; Rats, Zucker; Receptor, Cannabinoid, CB1; RNA, Messenger; Transcription Factors | 2015 |