deoxycytidine and apricitabine

deoxycytidine has been researched along with apricitabine in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	21 (87.50)	29.6817
2010's	3 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Nelson, MR; Waters, L	1
Bethell, RC; Lie, YS; Parkin, NT	1
Allard, B; Bethell, RC; de Muys, JM; Gu, Z; Lippens, J; McKenna, P; Nguyen-Ba, N; Rando, RF; Ren, C; Taylor, DL	1
Bethell, RC; Cahn, P; Cassetti, I; Phanuphak, P; Sawyer, J; Shiveley, L; Wood, R	1
Babayeva, M; Dontabhaktuni, A; Nakatani-Freshwater, T; Taft, DR	1
Holdich, T; Sawyer, J; Shiveley, L	1
Holdich, T; Sawyer, J; Shiveley, LA	1
Bethell, R; Collins, P; De Muys, J; Hamelin, B; Lippens, J; Ren, C; Richard, A	1
Bethell, RC; Cahn, P; Cox, S; Sawyer, J; Wainberg, MA	1
Coutsinos, D; Frankel, FA; Wainberg, MA; Xu, H	1
Bethell, R; de Baar, MP; de Rooij, ER; Smolders, KG; Timmermans, EC; van Schijndel, HB	1
Brenner, BG; Lalonde, R; Micheli, V; Moisi, D; Ntemgwa, M; Oliveira, M; Wainberg, MA	1
Cahn, P; Cassetti, I; Holdich, T; Rolon, M; Sawyer, J; Shiveley, L	1
Cox, S; Sawyer, J; Shiveley, L; Struthers-Semple, C	1
Holdich, T; Sawyer, J	1
Pozniak, A	1
Dalton, P	1
Brenner, BG; Cox, S; Moisi, D; Oliveira, M; Spira, B; Wainberg, MA	1
Cox, S; Southby, J	1
Belliveau, PP; Gaffney, MM; Spooner, LM	1
Borin, M; Cox, S; Linet, O; Perry, K; Southby, J; Tackwell, K	1
Cahn, P; Wainberg, MA	1
Altclas, J; Cahn, P; Cassetti, I; Cooper, DA; Cox, S; Losso, M; Martins, M	1
Babayeva, M; Cox, S; Taft, DR; White, MP	1

Reviews

5 review(s) available for deoxycytidine and apricitabine

Article	Year
New drugs. HIV medicine, 2005, Volume: 6, Issue:4 Topics: Anti-HIV Agents; Benzophenones; Cytidine Triphosphate; Darunavir; Deoxycytidine; Emtricitabine; HIV; HIV Fusion Inhibitors; HIV Reverse Transcriptase; Humans; Imidazoles; Nitriles; Protease Inhibitors; Pyridazines; Pyridines; Pyrimidines; Pyrones; Reverse Transcriptase Inhibitors; Sulfonamides; Sulfur Compounds; Zalcitabine	2005
Apricitabine: a novel deoxycytidine analogue nucleoside reverse transcriptase inhibitor for the treatment of nucleoside-resistant HIV infection. Antiviral chemistry & chemotherapy, 2007, Volume: 18, Issue:2 Topics: Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; HIV Infections; Humans	2007
Apricitabine--a novel nucleoside reverse transcriptase inhibitor for the treatment of HIV infection that is refractory to existing drugs. Expert opinion on investigational drugs, 2009, Volume: 18, Issue:2 Topics: Animals; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; HIV Infections; HIV-1; Humans; Reverse Transcriptase Inhibitors	2009
Apricitabine: a nucleoside reverse transcriptase inhibitor for HIV infection. The Annals of pharmacotherapy, 2009, Volume: 43, Issue:10 Topics: Anti-HIV Agents; Clinical Trials as Topic; Deoxycytidine; Drug Approval; Drug Resistance, Viral; HIV Infections; Humans; Prodrugs; United States; United States Food and Drug Administration	2009
Resistance profile of the new nucleoside reverse transcriptase inhibitor apricitabine. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:2 Topics: Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Mutation, Missense	2010

Trials

8 trial(s) available for deoxycytidine and apricitabine

Article	Year
Efficacy and tolerability of 10-day monotherapy with apricitabine in antiretroviral-naive, HIV-infected patients. AIDS (London, England), 2006, Jun-12, Volume: 20, Issue:9 Topics: Administration, Oral; Adult; Argentina; Deoxycytidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; HIV Infections; HIV-1; Humans; Lymphocyte Count; Male; Mutation; Reverse Transcriptase Inhibitors; RNA, Viral; South Africa; Thailand; Viral Load	2006
Pharmacokinetics of single oral doses of apricitabine, a novel deoxycytidine analogue reverse transcriptase inhibitor, in healthy volunteers. Clinical drug investigation, 2006, Volume: 26, Issue:5 Topics: Administration, Oral; Adult; Area Under Curve; Chromatography, Liquid; Deoxycytidine; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Molecular Structure; Reverse Transcriptase Inhibitors; Sex Factors; Stereoisomerism; Tandem Mass Spectrometry; Time Factors	2006
Effect of Lamivudine on the plasma and intracellular pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in healthy volunteers. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Adolescent; Adult; Anti-HIV Agents; Cross-Over Studies; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Volunteers	2007
Multiple-dose pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in patients with HIV-1 infection. Clinical drug investigation, 2008, Volume: 28, Issue:2 Topics: Administration, Oral; Adult; Amylases; Area Under Curve; Biological Availability; Capsules; CD4 Lymphocyte Count; Deoxycytidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Half-Life; Headache; HIV Infections; HIV-1; Humans; Nasal Obstruction; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism	2008
Pharmacokinetics of apricitabine, a novel nucleoside reverse transcriptase inhibitor, in healthy volunteers treated with trimethoprim-sulphamethoxazole. Journal of clinical pharmacy and therapeutics, 2008, Volume: 33, Issue:1 Topics: Administration, Oral; Adult; Anti-HIV Agents; Anti-Infective Agents; Area Under Curve; Deoxycytidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination	2008
Influence of food on the pharmacokinetics of apricitabine, a novel deoxycytidine analogue reverse transcriptase inhibitor. Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:12 Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Chromatography, Liquid; Cross-Over Studies; Deoxycytidine; Dietary Fats; Fasting; Food-Drug Interactions; Humans; Male; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry	2008
Comparison of the pharmacokinetics of apricitabine in the presence and absence of ritonavir-boosted tipranavir: a phase I, open-label, controlled, single-centre study. Clinical drug investigation, 2009, Volume: 29, Issue:11 Topics: Adolescent; Adult; Anti-HIV Agents; Area Under Curve; Deoxycytidine; Drug Interactions; Humans; Male; Pyridines; Pyrones; Sulfonamides	2009
Antiviral activity of apricitabine in treatment-experienced HIV-1-infected patients with M184V who are failing combination therapy. HIV medicine, 2011, Volume: 12, Issue:6 Topics: Adult; Anti-HIV Agents; Argentina; Australia; Deoxycytidine; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Male; Middle Aged; Mutation; Treatment Outcome; Viral Load; Virus Replication; Young Adult	2011

Other Studies

11 other study(ies) available for deoxycytidine and apricitabine

Article	Year
In vitro activity of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor (NRTI), against 215 HIV-1 isolates resistant to other NRTIs. Antiviral chemistry & chemotherapy, 2005, Volume: 16, Issue:5 Topics: Deoxycytidine; Drug Resistance, Viral; HIV-1; Microbial Sensitivity Tests; Mutation; Reverse Transcriptase Inhibitors	2005
In vitro antiretroviral activity and in vitro toxicity profile of SPD754, a new deoxycytidine nucleoside reverse transcriptase inhibitor for treatment of human immunodeficiency virus infection. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2 Topics: Anti-HIV Agents; Bone Marrow; Deoxycytidine; DNA, Mitochondrial; HIV-1; Humans; Mitochondria; Reverse Transcriptase Inhibitors	2006
Effects of trimethoprim on the clearance of apricitabine, a deoxycytidine analog reverse transcriptase inhibitor, and Lamivudine in the isolated perfused rat kidney. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2 Topics: Animals; Anti-Infective Agents; Deoxycytidine; Drug Interactions; Kidney; Lamivudine; Male; Perfusion; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Trimethoprim	2006
In vitro interactions between apricitabine and other deoxycytidine analogues. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8 Topics: Anti-HIV Agents; Deoxycytidine; Drug Interactions; Emtricitabine; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Microbial Sensitivity Tests; Reverse Transcriptase Inhibitors	2007
Kinetics of inhibition of HIV type 1 reverse transcriptase-bearing NRTI-associated mutations by apricitabine triphosphate. Antiviral chemistry & chemotherapy, 2007, Volume: 18, Issue:2 Topics: Amino Acid Sequence; Deoxycytidine; HIV Reverse Transcriptase; Kinetics; Molecular Sequence Data; Mutation; Reverse Transcriptase Inhibitors	2007
Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells. Antiviral research, 2007, Volume: 76, Issue:1 Topics: Adenine; Deoxycytidine; DNA Replication; DNA, Mitochondrial; Hepatocytes; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir	2007
Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Adenine; Amino Acid Sequence; Deoxycytidine; Drug Resistance, Multiple, Viral; Genetic Variation; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Mutation; Organophosphonates; Phenotype; Ribonuclease H; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid; Tenofovir; Zidovudine	2007
New drugs. Journal of HIV therapy, 2008, Volume: 13, Issue:2 Topics: Animals; Anti-HIV Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Multiple, Viral; HIV Antibodies; HIV Fusion Inhibitors; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Mutation; Nitriles; Nucleosides; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Succinates; Triterpenes; Virus Internalization	2008
Apricitabine continues to show good results. Project Inform perspective, 2008, Issue:46 Topics: Deoxycytidine; HIV Infections; Humans; Reverse Transcriptase Inhibitors; Treatment Outcome	2008
Apricitabine does not select additional drug resistance mutations in tissue culture in human immunodeficiency virus type 1 variants containing K65R, M184V, or M184V plus thymidine analogue mutations. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4 Topics: Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Zidovudine	2009
Renal excretion of apricitabine in rats: ex vivo and in vivo studies. European journal of drug metabolism and pharmacokinetics, 2011, Volume: 36, Issue:3 Topics: Animals; Blood Proteins; Deoxycytidine; Drug Interactions; Kidney; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors	2011