deoxyaminopteroic acid has been researched along with methotrexate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (43.48) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Paxton, JW | 1 |
| Ahern, MJ; Hall, PD; Harley, H; Hayball, PJ; Hill, W; Kevat, S | 1 |
| Breithaupt, H; Hartmann, R; Henze, G; Hepp, R; Wolfrom, C | 1 |
| Alkaysi, HN; Gharaibeh, AM; Salem, MA | 1 |
| Beverley, SM; Ellenberger, TE; Rosowsky, A; Wright, JE | 1 |
| Faulkner, R; Furst, DE; Kohlbrenner, M; Nuernberg, B | 1 |
| Farid, YY; Skellern, GG; Stewart, MJ; Watson, ID | 1 |
| Frantisek, J; Salamoun, J | 1 |
| Anstead, GM; Freisheim, JH; Kempton, RJ; Kumar, AA; Price, EM | 1 |
| Cairnes, DA; Evans, WE | 2 |
| Breithaupt, H; Goebel, G; Küenzlen, E | 1 |
| Farquhar, D; Loo, TL; Pegues, JC; Smith, RG; Wang, YM | 1 |
| Bertino, JR; DeAngelis, LM; Fleisher, M; Lin, S; Tong, WP | 1 |
| Dyer, JC; Hu, JC; Kopytek, SJ; Standaert, RF | 1 |
| Adamson, PC; Anderson, L; Balis, FM; Hawkins, M; McCully, C; Monitjo, KS; Salzer, WL; Sung, E; Widemann, BC | 1 |
| Milone, MC | 1 |
| Balis, FM; Fox, E | 1 |
| Hara, S; Jimi, S; Matsumoto, T; Takamatsu, Y; Tamura, K; Uchiyama, M | 1 |
| Klapkova, E; Kotaska, K; Kukacka, J; Prusa, R; Suchanska, I; Urinovska, R | 1 |
| Carlow, DC; Fleisher, M; Grace, M; Murata, K; Pessin, MS; Ramanathan, LV; Schofield, RC | 1 |
| Barceló, B; Berga, F; Costa-Bauza, A; Elorza, MÁ; Gimenez, S; Gomila, I; Grases, F; Luna, P; Martorell, C; Rey, J; Sánchez, I | 1 |
| Cui, Y; Lin, S; Mei, S; Ren, X; Yu, K; Zeng, C; Zhang, D; Zhao, Z | 1 |
23 other study(ies) available for deoxyaminopteroic acid and methotrexate
| Article | Year |
|---|---|
Interference of 4-amino-4-deoxy-N10-methylpteroic acid with the radioimmunoassay of methotrexate.
Topics: Animals; Feces; Humans; Methotrexate; Mice; Radioimmunoassay; Rats | 1979 |
Hepatic methotrexate content and progression of hepatic fibrosis: preliminary findings.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Female; Fibrosis; Humans; Image Interpretation, Computer-Assisted; Liver; Male; Methotrexate; Middle Aged; Polyglutamic Acid | 1991 |
Pharmacokinetic study of methotrexate, folinic acid and their serum metabolites in children treated with high-dose methotrexate and leucovorin rescue.
Topics: Child; Child, Preschool; Chromatography, High Pressure Liquid; Half-Life; Humans; Leucovorin; Metabolic Clearance Rate; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1990 |
High-performance liquid chromatographic determination of methotrexate in plasma.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Humans; Methotrexate; Spectrophotometry, Ultraviolet; Theophylline | 1990 |
Wild-type and drug-resistant Leishmania major hydrolyze methotrexate to N-10-methyl-4-deoxy-4-aminopteroate without accumulation of methotrexate polyglutamates.
Topics: Animals; Biological Transport; Biotransformation; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Resistance; Kinetics; Leishmania tropica; Methotrexate; Mutation; Peptides; Polyglutamic Acid | 1989 |
Rapid quantitation of methotrexate and its metabolites in human serum, urine and bile, using solid-phase extraction and high-performance liquid chromatography.
Topics: Bile; Chromatography, High Pressure Liquid; Humans; Methotrexate; Spectrophotometry, Ultraviolet | 1989 |
An investigation into the source of the deglutamated metabolites of methotrexate in patients treated with high dose infusions.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Humans; Infusions, Intravenous; Leucovorin; Liver; Methotrexate; Microbial Sensitivity Tests; Neoplasms; Oxidation-Reduction | 1986 |
Determination of methotrexate and its metabolites 7-hydroxymethotrexate and 2,4-diamino-N10-methylpteroic acid in biological fluids by liquid chromatography with fluorimetric detection.
Topics: Body Fluids; Chromatography, High Pressure Liquid; Humans; Methotrexate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1986 |
High-performance liquid chromatography of methotrexate analogs containing terminal lysine or ornithine and their dansyl derivatives.
Topics: Chromatography, High Pressure Liquid; Dansyl Compounds; Fluorescence; Glutamates; Lysine; Methotrexate; Ornithine | 1983 |
A simple preparation of the methotrexate metabolites 7-hydroxymethotrexate and 4-deoxy-4-amino-N10-methylpteroic acid.
Topics: Animals; Biotransformation; In Vitro Techniques; Liver; Mass Spectrometry; Methotrexate; Rabbits | 1983 |
Rapid high-pressure liquid chromatographic determination of methotrexate and its metabolites 7-hydroxymethotrexate and 2,4-diamino-N(10)-methylpteroic acid in biological fluids.
Topics: Chromatography, High Pressure Liquid; Humans; Methotrexate | 1982 |
High-performance liquid chromatographic assay of methotrexate, 7-hydroxymethortrexate, 4-deoxy-4-amino-N10-methylpteroic acid and sulfamethoxazole in serum, urine and cerebrospinal fluid.
Topics: Chromatography, High Pressure Liquid; Humans; Methotrexate; Sulfamethoxazole; Time Factors | 1982 |
Mass spectrometry of permethylated folic acid analogs.
Topics: Chromatography, High Pressure Liquid; Electrons; Folic Acid; Humans; Mass Spectrometry; Methotrexate | 1981 |
Carboxypeptidase G2 rescue after high-dose methotrexate.
Topics: Antimetabolites, Antineoplastic; Central Nervous System Neoplasms; Female; gamma-Glutamyl Hydrolase; Humans; Lymphoma; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects | 1996 |
Chemically induced dimerization of dihydrofolate reductase by a homobifunctional dimer of methotrexate.
Topics: Binding Sites; Biological Availability; Chromatography, Gel; Dimerization; Escherichia coli; Ligands; Macromolecular Substances; Methotrexate; Organophosphorus Compounds; Tetrahydrofolate Dehydrogenase | 2000 |
Pharmacokinetics and metabolism of the methotrexate metabolite 2, 4-diamino-N(10)-methylpteroic acid.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Macaca mulatta; Male; Mass Spectrometry; Methotrexate; Tumor Cells, Cultured | 2000 |
Commentary.
Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma | 2010 |
Commentary.
Topics: Acute Kidney Injury; Adolescent; Antimetabolites, Antineoplastic; Bias; Bone Neoplasms; gamma-Glutamyl Hydrolase; Humans; Immunoassay; Methotrexate; Osteosarcoma | 2010 |
Simple and sensitive HPLC method for the fluorometric determination of methotrexate and its major metabolites in human plasma by post-column photochemical reaction.
Topics: Aged; Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Humans; Limit of Detection; Linear Models; Lymphoma, Large B-Cell, Diffuse; Male; Methotrexate; Ornithine; Photolysis; Reproducibility of Results; Spectrometry, Fluorescence | 2012 |
The influence of 7-OH methotrexate metabolite on clinical relevance of methotrexate determination.
Topics: Adolescent; Antimetabolites, Antineoplastic; Biotransformation; Bone Neoplasms; Child; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization Immunoassay; Humans; Methotrexate; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Young Adult | 2011 |
Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum.
Topics: Chromatography, Liquid; Humans; Limit of Detection; Methotrexate; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
2,4-Diamino-N10-methylpteroic acid (DAMPA) crystalluria in a patient with osteosarcoma treated with carboxypeptidase-G2 rescue after high-dose methotrexate-induced nephrotoxicity.
Topics: Adult; Female; gamma-Glutamyl Hydrolase; Humans; Hydrolysis; Kidney; Methotrexate; Osteosarcoma; Particle Size; Surface Properties | 2018 |
Simultaneous Determination of Urine Methotrexate, 7-Hydroxy Methotrexate, Deoxyaminopteroic Acid, and 7-Hydroxy Deoxyaminopteroic Acid by UHPLC-MS/MS in Patients Receiving High-dose Methotrexate Therapy.
Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Methotrexate; Tandem Mass Spectrometry; Time Factors; Urinalysis | 2020 |