dendrobine has been researched along with coriolin* in 1 studies
1 other study(ies) available for dendrobine and coriolin
| Article | Year |
|---|---|
Application of chiral cationic catalysts to several classical syntheses of racemic natural products transforms them into highly enantioselective pathways.
This paper describes the application of chiral oxazaborolidinium cations of type 2 to various enantioselective Diels-Alder reactions that have served as early key steps for the syntheses of complex natural products. In the original syntheses these Diels-Alder reactions produced racemic adducts and led to racemic target molecules unless a separation of enantiomers by classical resolution was employed. By use of chiral catalysts of type 2, chiral products were obtained directly from Diels-Alder reactions of achiral components in excellent yield and enantioselectivity and with the mechanistically predicted absolute configuration. As a result, a number of classical syntheses could be converted to enantioselective versions, including (1) cortisone/cortisol (Merck/Sarett), (2) dendrobine (Kende), (3) vitamin B(12) (Eschenmoser), (4) myrocin C (Chu-Moyer/Danishefsky), (5) coriolin and hirsutene (Mehta), (6) dendrobatid 251F (Aube), (7) silphinene (Ito), and (8) nicandrenone core (Stoltz/Corey). Topics: Alkaloids; Biological Products; Boron Compounds; Catalysis; Cortisone; Diterpenes; Photochemistry; Polycyclic Sesquiterpenes; Sesquiterpenes; Stereoisomerism; Vitamin B 12 | 2004 |