Page last updated: 2024-08-22

denatonium benzoate and quinine

denatonium benzoate has been researched along with quinine in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (28.00)	18.2507
2000's	12 (48.00)	29.6817
2010's	6 (24.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gannon, KS; Margolskee, RF; Wong, GT	1
Nelson, SL; Sanregret, JD	1
Caprio, J; Marui, T; Ogawa, K	1
Nakashima, K; Ninomiya, Y	2
Hayashi, Y; Mori, T; Seto, E	1
Margolskee, RF; Ming, D; Ninomiya, Y	1
Cubero-Castillo, E; Noble, AC	1
Damak, S; Danilova, V; He, W; Hellekant, G; Margolskee, RF; Max, M; Zou, S	1
Caicedo, A; Margolskee, RF; Pereira, E; Roper, SD	1
Chan, CY; Travers, SP; Yoo, JE	1
Damak, S; He, W; Lem, J; Margolskee, RF; Ninomiya, Y; Varadarajan, V; Yamada, A; Yasumatsu, K	1
Dotson, CD; Roper, SD; Spector, AC	1
Damak, S; Glendinning, JI; Kokrashvili, Z; Margolskee, RF; Mosinger, B; Ninomiya, Y; Pérez, CA; Rong, M; Shigemura, N; Yasumatsu, K; Yoshida, R	1
Rowe, C; Skelhorn, J	1
Maehashi, K; Matano, M; Nonaka, M; Udaka, S; Yamamoto, Y	1
Margolskee, RF; Nilius, B; Ninomiya, Y; Talavera, K; Voets, T; Yasumatsu, K; Yoshida, R	1
Hernandez Salazar, LT; Laska, M; Rivas Bautista, RM	1
Barrows, J; Finger, TE; Hallock, RM; Tatangelo, M	1
Bhullar, RP; Chelikani, P; Pydi, SP	1
Guerin, PM; Kessler, S; Vlimant, M	1
Adner, M; Al-Ameri, M; Bergman, P; Dahlén, SE; James, A; Manson, ML; Orre, AC; Säfholm, J; Swärd, K	1
Mansfield, CJ; Mathew, PS; Mennella, JA; Reed, DR; Roberts, KM	2
Andrew, K; Green, BG	1

Trials

2 trial(s) available for denatonium benzoate and quinine

Article	Year
Effect of compound sequence on bitterness enhancement. Chemical senses, 2001, Volume: 26, Issue:4 Topics: Administration, Oral; Adult; Area Under Curve; Caffeine; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Female; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Quinine; Sensation; Sensitivity and Specificity; Taste	2001
Age-related differences in bitter taste and efficacy of bitter blockers. PloS one, 2014, Volume: 9, Issue:7 Topics: Adult; Aging; Caffeine; Child; Child, Preschool; Female; Genotype; Gluconates; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sodium Glutamate; Taste; Taste Buds	2014

Other Studies

23 other study(ies) available for denatonium benzoate and quinine

Article	Year
Transduction of bitter and sweet taste by gustducin. Nature, 1996, Jun-27, Volume: 381, Issue:6585 Topics: Animals; Cloning, Molecular; Facial Nerve; Female; Guanidines; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Quaternary Ammonium Compounds; Quinine; Signal Transduction; Sodium Chloride; Sucrose; Sweetening Agents; Taste; Taste Buds; Transducin	1996
Response of pigs to bitter-tasting compounds. Chemical senses, 1997, Volume: 22, Issue:2 Topics: Animals; Caffeine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Male; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Quinine; Random Allocation; Reference Standards; Sucrose; Swine; Swine, Miniature; Taste; Water	1997
Quinine suppression of single facial taste fiber responses in the channel catfish. Brain research, 1997, Sep-26, Volume: 769, Issue:2 Topics: Amino Acids; Animals; Caffeine; Electrophysiology; Face; Ictaluridae; Nerve Fibers; Quaternary Ammonium Compounds; Quinine; Stimulation, Chemical; Taste	1997
Increase in inositol 1,4,5-triphosphate levels of the fungiform papilla in response to saccharin and bitter substances in mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1998, Volume: 8, Issue:4 Topics: Animals; Female; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred C57BL; Pronase; Quaternary Ammonium Compounds; Quinine; Saccharin; Sucrose; Taste; Taste Buds; Tongue	1998
Patch clamp recording of the responses to three bitter stimuli in mouse taste cells. Cellular and molecular biology (Noisy-le-Grand, France), 1999, Volume: 45, Issue:3 Topics: Animals; Electrophysiology; Female; Flavanones; Flavonoids; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Quaternary Ammonium Compounds; Quinine; Signal Transduction; Stimulation, Chemical; Taste Buds	1999
Transduction for sweet taste of saccharin may involve both inositol 1,4,5-trisphosphate and cAMP pathways in the fungiform taste buds in C57BL mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1999, Volume: 9, Issue:2 Topics: Animals; Chorda Tympani Nerve; Cyclic AMP; Female; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred C57BL; Quaternary Ammonium Compounds; Quinine; Saccharin; Signal Transduction; Taste; Taste Buds; Tongue	1999
Blocking taste receptor activation of gustducin inhibits gustatory responses to bitter compounds. Proceedings of the National Academy of Sciences of the United States of America, 1999, Aug-17, Volume: 96, Issue:17 Topics: Adenosine Monophosphate; Animals; Cattle; Electrophysiology; Glossopharyngeal Nerve; Male; Mice; Mice, Inbred C57BL; Nicotine; Quaternary Ammonium Compounds; Quinine; Sensory Receptor Cells; Strychnine; Taste; Transducin	1999
Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin. Chemical senses, 2002, Volume: 27, Issue:8 Topics: Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Guanidines; Immunohistochemistry; Luminescent Proteins; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; Polymerase Chain Reaction; Promoter Regions, Genetic; Quaternary Ammonium Compounds; Quinine; Sucrose; Sweetening Agents; Taste; Taste Buds; Transducin; Transgenes	2002
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Oct-29, Volume: 23, Issue:30 Topics: Animals; Calcium; Citric Acid; Cycloheximide; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Protein Subunits; Quaternary Ammonium Compounds; Quinine; Stimulation, Chemical; Taste; Taste Buds; Transducin	2003
Diverse bitter stimuli elicit highly similar patterns of Fos-like immunoreactivity in the nucleus of the solitary tract. Chemical senses, 2004, Volume: 29, Issue:7 Topics: Animals; Behavior, Animal; Brain Mapping; Citric Acid; Immunohistochemistry; Male; Propylthiouracil; Proto-Oncogene Proteins c-fos; Quaternary Ammonium Compounds; Quinine; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Taste	2004
Umami taste responses are mediated by alpha-transducin and alpha-gustducin. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Sep-01, Volume: 24, Issue:35 Topics: Animals; Chorda Tympani Nerve; Crosses, Genetic; Food Preferences; Genotype; Glossopharyngeal Nerve; Glutamates; Guanidines; Inosine Monophosphate; Membrane Glycoproteins; Mice; Mice, Knockout; Quaternary Ammonium Compounds; Quinine; Receptors, Cell Surface; Sodium Glutamate; Sucrose; Taste; Taste Buds; Toll-Like Receptors; Transducin	2004
PLCbeta2-independent behavioral avoidance of prototypical bitter-tasting ligands. Chemical senses, 2005, Volume: 30, Issue:7 Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; Ligands; Mice; Mice, Knockout; Nerve Tissue Proteins; Phosphoinositide Phospholipase C; Quaternary Ammonium Compounds; Quinine; Sensory Thresholds; Signal Transduction; Stimulation, Chemical; Sucrose; Taste; Type C Phospholipases	2005
Trpm5 null mice respond to bitter, sweet, and umami compounds. Chemical senses, 2006, Volume: 31, Issue:3 Topics: Animals; Behavior, Animal; Chorda Tympani Nerve; Dose-Response Relationship, Drug; Gene Deletion; Glossopharyngeal Nerve; Hydrochloric Acid; Mice; Mice, Knockout; Quaternary Ammonium Compounds; Quinine; Reaction Time; Sodium Chloride; Sodium Glutamate; Stimulation, Chemical; Sweetening Agents; Taste; TRPM Cation Channels	2006
Predators' toxin burdens influence their strategic decisions to eat toxic prey. Current biology : CB, 2007, Sep-04, Volume: 17, Issue:17 Topics: Animals; Avoidance Learning; Body Burden; Color; Decision Making; Diet; Eating; Female; Larva; Male; Predatory Behavior; Quaternary Ammonium Compounds; Quinine; Starlings; Tenebrio; Toxins, Biological	2007
Riboflavin-binding protein is a novel bitter inhibitor. Chemical senses, 2008, Volume: 33, Issue:1 Topics: Acid Phosphatase; Adult; Caffeine; Dipeptides; Egg White; Egg Yolk; Female; Flavanones; Humans; Lactoglobulins; Male; Membrane Transport Proteins; Ovalbumin; Protein Binding; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Serum Albumin, Bovine; Taste; Theobromine	2008
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, Volume: 22, Issue:5 Topics: Animals; Cells, Cultured; Chorda Tympani Nerve; Electric Conductivity; Humans; Ion Channel Gating; Mice; Patch-Clamp Techniques; Quaternary Ammonium Compounds; Quinidine; Quinine; Sucrose; Taste; TRPM Cation Channels	2008
Gustatory responsiveness to six bitter tastants in three species of nonhuman primates. Journal of chemical ecology, 2009, Volume: 35, Issue:5 Topics: Animals; Atelinae; Behavior, Animal; Benzyl Alcohols; Caffeine; Choice Behavior; Flavanones; Food Preferences; Glucosides; Macaca nemestrina; Primates; Quaternary Ammonium Compounds; Quinine; Saimiri; Species Specificity; Sucrose; Taste; Taste Threshold	2009
Residual chemosensory capabilities in double P2X2/P2X3 purinergic receptor null mice: intraoral or postingestive detection? Chemical senses, 2009, Volume: 34, Issue:9 Topics: Animals; Citric Acid; Food Preferences; Gene Knockdown Techniques; Hydrochloric Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Oropharynx; Quaternary Ammonium Compounds; Quinine; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Sucrose; Taste; Time Factors	2009
Constitutively active mutant gives novel insights into the mechanism of bitter taste receptor activation. Journal of neurochemistry, 2012, Volume: 122, Issue:3 Topics: Alanine; Amino Acids; Calcium; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hydrogen Bonding; Models, Molecular; Mutation; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Stimulation, Chemical; Taste; Transfection	2012
The sugar meal of the African malaria mosquito Anopheles gambiae and how deterrent compounds interfere with it: a behavioural and neurophysiological study. The Journal of experimental biology, 2013, Apr-01, Volume: 216, Issue:Pt 7 Topics: Action Potentials; Analysis of Variance; Animals; Anopheles; Berberine; Caffeine; Chemoreceptor Cells; Feeding Behavior; Female; Fructose; Glucose; Microscopy, Electron, Transmission; Nigeria; Quaternary Ammonium Compounds; Quinidine; Quinine; Sensilla; Sucrose	2013
Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle. European journal of pharmacology, 2014, Oct-05, Volume: 740 Topics: Aged; Animals; Aorta, Thoracic; Chloroquine; Colon; Dextromethorphan; Female; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Mice, Knockout; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Noscapine; Pulmonary Artery; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Saccharin; Taste; Trachea	2014
"A spoonful of sugar helps the medicine go down": bitter masking by sucrose among children and adults. Chemical senses, 2015, Volume: 40, Issue:1 Topics: Adult; Caffeine; Child; Child, Preschool; Female; Genotype; Heterozygote; Humans; Male; Propylthiouracil; Quaternary Ammonium Compounds; Quinine; Receptors, G-Protein-Coupled; Sucrose; Taste Threshold; Urea	2015
Stimulus-Dependent Effects of Temperature on Bitter Taste in Humans. Chemical senses, 2017, Volume: 42, Issue:2 Topics: Adolescent; Adult; Female; Flavanones; Humans; Male; Middle Aged; Quaternary Ammonium Compounds; Quinine; Taste; Temperature; Tongue; Young Adult	2017