demethylcantharidin and endothall

demethylcantharidin has been researched along with endothall* in 1 studies

Other Studies

1 other study(ies) available for demethylcantharidin and endothall

Article	Year
Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity. Chemistry & biodiversity, 2008, Volume: 5, Issue:10 Two platinum(IV) complexes (OC-6-33)-dichlorido(ethane-1,2-diamine)dihydroxidoplatinum(IV) and (OC-6-33)-diammine(dichlorido)dihydroxidoplatinum(IV) were carboxylated using demethylcantharidin as carboxylation agent. The complexes were characterized by elemental analysis, mass spectrometry, multinuclear (1H, 13C, 15N, and 195Pt) NMR spectroscopy, and, in case of (OC-6-33)-diamminebis(3-carboxy-7exo-oxabicyclo[2.2.1]heptane-2-carboxylato)dichloridoplatinum(IV) via X-ray diffraction. Cytotoxicity of the complexes was studied in seven human cancer cell lines representing five tumor entities, i.e., ovarian carcinoma (CH1, SK-OV-3), cervical carcinoma (HeLa), colon carcinoma (SW480, HCT-116), osteosarcoma (U-2 OS), and hepatocellular carcinoma (Hep G2) by means of the MTT (=3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium hydrobromide) assay. Topics: Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Dicarboxylic Acids; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organoplatinum Compounds; Platinum	2008

Article

Year

Novel endothall-containing platinum(IV) complexes: synthesis, characterization, and cytotoxic activity.

Chemistry & biodiversity, 2008, Volume: 5, Issue:10

Two platinum(IV) complexes (OC-6-33)-dichlorido(ethane-1,2-diamine)dihydroxidoplatinum(IV) and (OC-6-33)-diammine(dichlorido)dihydroxidoplatinum(IV) were carboxylated using demethylcantharidin as carboxylation agent. The complexes were characterized by elemental analysis, mass spectrometry, multinuclear (1H, 13C, 15N, and 195Pt) NMR spectroscopy, and, in case of (OC-6-33)-diamminebis(3-carboxy-7exo-oxabicyclo[2.2.1]heptane-2-carboxylato)dichloridoplatinum(IV) via X-ray diffraction. Cytotoxicity of the complexes was studied in seven human cancer cell lines representing five tumor entities, i.e., ovarian carcinoma (CH1, SK-OV-3), cervical carcinoma (HeLa), colon carcinoma (SW480, HCT-116), osteosarcoma (U-2 OS), and hepatocellular carcinoma (Hep G2) by means of the MTT (=3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium hydrobromide) assay.

Topics: Antineoplastic Agents; Cantharidin; Cell Line, Tumor; Cell Survival; Crystallography, X-Ray; Dicarboxylic Acids; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organoplatinum Compounds; Platinum

2008