demeclocycline and ferric-sulfate

(1) To present a narrative review of the currently available alternative interventions and materials to formocresol pulpotomy for the management of extensive caries in the primary molar, and (2) to produce a clinical protocol for pulp therapy techniques in the extensively carious primary molar.. The International Agency for Research on Cancer has recently classified formaldehyde as carcinogenic to human beings. Since Buckley's Formocresol contains 19% formaldehyde in its full strength and, therefore, 1% in a 20% dilution, a safer alternative should be identified.. A narrative review of the published literature for primary molar pulp therapy techniques was undertaken following an extensive and appropriate literature search. A specialist group of paediatric dentists was formed to arrive at a consensus and establish an evidence-based protocol for the management of extensively carious primary molar teeth. Part I of this paper explores the currently available alternative interventions and materials to formocresol in the form of a narrative review. The second part of the paper will present the formation of a specialist group to arrive at a consensus and establish an evidence-based protocol for the management of the extensively carious primary molar.. After consideration of a review of extensively searched literature, a protocol and key points document have been developed to assist clinicians in their treatment planning. Further long-term studies with the highest level of evidence (i.e. randomized controlled trials) are required to enable us to identify acceptable alternatives which can replace formocresol.

Topics: Aluminum Compounds; Animals; Bone Morphogenetic Proteins; Calcium Compounds; Calcium Hydroxide; Camphor; Collagen; Demeclocycline; Dental Pulp Capping; Dental Pulp Devitalization; Dental Pulp Exposure; Drug Combinations; Electrosurgery; Ferric Compounds; Formocresols; Glutaral; Humans; Hydrocarbons, Iodinated; Laser Therapy; Oxides; Pulpectomy; Pulpotomy; Root Canal Filling Materials; Silicates; Silicones; Tooth Remineralization; Triamcinolone Acetonide; Zinc Oxide-Eugenol Cement