Page last updated: 2024-09-03

deltorphin ii, ala(2)- and naltrindole

deltorphin ii, ala(2)- has been researched along with naltrindole in 33 studies

Compound Research Comparison

Studies (deltorphin ii, ala(2)-)	Recent Studies (post-2010) (deltorphin ii, ala(2)-)	Studies (naltrindole)	Recent Studies (post-2010) (naltrindole)
7	3	801	139
6	2	801	139
233	20	801	139

Protein Interaction Comparison

Protein	Taxonomy	deltorphin ii, ala(2)- (IC50)	naltrindole (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)		0.0007
Delta-type opioid receptor	Homo sapiens (human)		0.0006

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	18 (54.55)	18.2507
2000's	11 (33.33)	29.6817
2010's	4 (12.12)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aguzzi, A; Benke, D; Gao, B; Hagenbuch, B; Kullak-Ublick, GA; Meier, PJ	1
Fujii, H; Iwata, S; Koyama, Y; Kutsumura, N; Miyata, Y; Nagase, H; Nakajima, R; Saitoh, T; Yamamoto, N	1
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L	1
Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A	1
Broccardo, M; Improta, G	1
Carboni, E; Di Chiara, G; Garau, L; Longoni, R; Melchiorri, P; Mulas, A; Spina, L	1
Angelucci, F; Negri, L; Noviello, V	1
Kamei, J; Misawa, M; Mizoguchi, H; Nagase, H; Suzuki, T; Yoshiike, M	1
Búzás, B; Cox, BM; Izenwasser, S	1
Kameyama, T; Mizutani, M; Sasaki, Y; Toyoshi, T; Ukai, M	1
Hammond, DL; Stewart, PE	1
Babin, E; Fang, L; Hruby, VJ; Knapp, RJ; Li, X; Malatynska, E; Nguyen, M; Roeske, WR; Santoro, G; Varga, EV	1
Búzás, B; Cox, BM; Izenwasser, S; Portoghese, PS	1
Acquas, E; Di Chiara, G; Meloni, M	1
Cheng, PY; Decena, J; McCabe, S; Soong, Y; Szeto, HH; Wu, D	1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T	1
Appleyard, SM; Davis, TP; Hruby, VJ; Knapp, RJ; Lipkowski, AW; Misicka, A; Slaninova, J; Weber, SJ; Yamamura, HI	1
Borsodi, A; Hosztafi, S; Nevin, ST; Rónai, AZ; Spetea, M; Tóth, G	1
Borsodi, A; Hill, RG; Kelly, MD; Kitchen, I; Toth, G	1
Butterworth, J; Clarke, PB; Fraser, GL; Godbout, C; Labarre, M; Payza, K; Schmidt, R	1
Clarke, PB; Ducharme, J; Fraser, GL; Parenteau, H; Perkins, MN; Tu, TM	1
Kieffer, BL; Maldonado, R; Matthes, HW; Melchiorri, P; Negri, L; Severini, C	1
Boudinot, E; Champagnat, J; Denavit-Saubié, M; Dubois, C; Foutz, AS; Kieffer, BL; Matthes, HW; Morin-Surun, MP	1
Arvidsson, U; Kela, J; Salmi, P; Wahlestedt, C	1
Brown, DR; Townsend, DW	1
Fujimura, T; Ito, K; Kawamura, S; Mizoguchi, H; Murayama, K; Nakayama, D; Sakurada, C; Sakurada, S; Sakurada, T; Sato, T; Watanabe, C; Watanabe, H	1
Huang, YY; Lai, J; Luo, MC; Ma, SW; Porreca, F; Shuster, SJ; Zhang, DQ	1
Chen, SR; Pan, HL; Wu, ZZ	1
Chen, SR; Pan, HL	1
Gyires, K; Zádori, Z	1
Cerqueira, DR; Ferreira, HS; Fregoneze, JB; Nascimento, AI	1
Hu, N; Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Xie, K; Yu, Y; Zhang, L	1
Brederson, JD; Honda, CN	1

Other Studies

33 other study(ies) available for deltorphin ii, ala(2)- and naltrindole

Article	Year
Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Aged; Animals; Anion Transport Proteins; Biological Transport; Blood-Brain Barrier; Carrier Proteins; Enkephalin, D-Penicillamine (2,5)-; Humans; Male; Molecular Weight; Oligopeptides; Opioid Peptides; Rats	2000
Investigation of 7-benzylidenenaltrexone derivatives as a novel structural antitrichomonal lead compound. Bioorganic & medicinal chemistry letters, 2015, Nov-01, Volume: 25, Issue:21 Topics: Antitrichomonal Agents; Benzylidene Compounds; Dose-Response Relationship, Drug; Female; Humans; Molecular Structure; Naltrexone; Receptors, Opioid, delta; Structure-Activity Relationship; Trichomonas Vaginitis	2015
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors. Molecular pharmacology, 1994, Volume: 45, Issue:2 Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software	1994
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA research monograph, 1998, Volume: 178 Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders	1998
Hypothermic effect of D-Ala-deltorphin II, a selective delta opioid receptor agonist. Neuroscience letters, 1992, May-25, Volume: 139, Issue:2 Topics: Animals; Body Temperature; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta	1992
(D-Ala2)deltorphin II: D1-dependent stereotypies and stimulation of dopamine release in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:6 Topics: Animals; Brain; Caudate Nucleus; Cerebral Ventricles; Dopamine; Endorphins; Functional Laterality; Indoles; Infusions, Parenteral; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Stereotyped Behavior	1991
Behavioural effects of deltorphins in rats. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: Analgesics; Animals; Behavior, Animal; Indoles; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Social Behavior; Stereotyped Behavior	1991
Blockade of delta-opioid receptors prevents morphine-induced place preference in mice. Japanese journal of pharmacology, 1994, Volume: 66, Issue:1 Topics: Analgesics; Animals; Benzylidene Compounds; Conditioning, Operant; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu	1994
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin	1993
Differential modulation of behavioral responses by [D-Ala2, NMePhe4, Gly-ol]enkephalin, [D-Ala2] deltorphin II and [D-Pen2, L-Pen5]enkephalin in the mouse. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:3 Topics: Analysis of Variance; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Naltrexone; Oligopeptides	1994
Activation of spinal delta-1 or delta-2 opioid receptors reduces carrageenan-induced hyperalgesia in the rat. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2 Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Male; Naltrexone; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord	1994
Identification of a human delta opioid receptor: cloning and expression. Life sciences, 1994, Volume: 54, Issue:25 Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Consensus Sequence; Enkephalins; Humans; Mice; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Oligopeptides; Open Reading Frames; Receptors, Opioid, delta; Sequence Alignment; Transfection	1994
Evidence for delta opioid receptor subtypes regulating adenylyl cyclase activity in rat brain. Life sciences, 1994, Volume: 54, Issue:7 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Analgesics; Animals; Benzylidene Compounds; Caudate Nucleus; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1994
Blockade of delta-opioid receptors in the nucleus accumbens prevents ethanol-induced stimulation of dopamine release. European journal of pharmacology, 1993, Jan-12, Volume: 230, Issue:2 Topics: Animals; Cocaine; Dopamine; Ethanol; Indoles; Male; Morphinans; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1993
Opioid-induced stimulation of fetal respiratory activity by [D-Ala2]deltorphin I. European journal of pharmacology, 1993, Jan-05, Volume: 230, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Electromyography; Female; Fetus; Indoles; Injections, Intraventricular; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pregnancy; Receptors, Opioid, delta; Respiration; Sheep	1993
Differential modulation of mu-opioid receptor-mediated antitussive activity by delta-opioid receptor agonists in mice. European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1 Topics: Animals; Antitussive Agents; Cough; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu	1993
[125I-Tyr1]biphalin binding to opioid receptors of rat brain and NG108-15 cell membranes. Life sciences, 1998, Volume: 62, Issue:14 Topics: Animals; Brain; Cell Line; Cell Membrane; Enkephalins; Iodine Radioisotopes; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid	1998
Affinity profiles of novel delta-receptor selective benzofuran derivatives of non-peptide opioids. Neurochemical research, 1998, Volume: 23, Issue:9 Topics: Animals; Benzeneacetamides; Benzofurans; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Naltrexone; Oligopeptides; Oxycodone; Oxymorphone; Pyrrolidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Tritium	1998
Weaning-induced development of delta-opioid receptors in rat brain: differential effects of guanine nucleotides and sodium upon ligand-receptor recognition. British journal of pharmacology, 1998, Volume: 125, Issue:5 Topics: Animals; Brain; Guanylyl Imidodiphosphate; In Vitro Techniques; Ligands; Naltrexone; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Sodium; Weaning	1998
Characterization of [125I]AR-M100613, a high-affinity radioligand for delta opioid receptors. Peptides, 1999, Volume: 20, Issue:11 Topics: Animals; Brain; Iodine Radioisotopes; Kinetics; Ligands; Male; Naltrexone; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	1999
The effects of delta agonists on locomotor activity in habituated and non-habituated rats. Life sciences, 2000, Jul-14, Volume: 67, Issue:8 Topics: Animals; Benzamides; Dose-Response Relationship, Drug; Drug Tolerance; Male; Motor Activity; Naltrexone; Oligopeptides; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta	2000
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene. British journal of pharmacology, 2001, Volume: 132, Issue:7 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens	2001
Respiratory function in adult mice lacking the mu-opioid receptor: role of delta-receptors. The European journal of neuroscience, 2001, Volume: 13, Issue:9 Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Male; Medulla Oblongata; Mice; Mice, Knockout; Naltrexone; Narcotic Antagonists; Neurons; Oligopeptides; Organ Culture Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Respiratory Center; Respiratory Physiological Phenomena	2001
Functional interactions between delta- and mu-opioid receptors in rat thermoregulation. European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2 Topics: Animals; Body Temperature; Body Temperature Regulation; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Opioid, delta; Receptors, Opioid, mu	2003
Pharmacological characterization of a 7-benzylidenenaltrexone-preferring opioid receptor in porcine ileal submucosa. British journal of pharmacology, 2003, Volume: 140, Issue:4 Topics: Amphibian Proteins; Animals; Anions; Benzamides; Benzylidene Compounds; Biological Transport, Active; Carrier Proteins; Diprenorphine; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Gastrointestinal Motility; Ileum; Intestinal Mucosa; Male; Naltrexone; Neurons, Afferent; Oligopeptides; Piperazines; Quinolines; Receptors, Opioid, delta; Receptors, Opioid, mu; Swine; Tritium	2003
A Tyr-W-MIF-1 analog containing D-Pro2 acts as a selective mu2-opioid receptor antagonist in the mouse. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, mu	2005
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons. Molecular pain, 2005, Sep-28, Volume: 1 Topics: Animals; Cell Line; Ganglia, Spinal; Gene Expression Regulation; Gene Knockdown Techniques; Injections, Spinal; Lumbar Vertebrae; Naltrexone; Neurons; Nociceptors; Oligopeptides; Pain Measurement; Peripheral Nervous System; Posterior Horn Cells; Quinolinium Compounds; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; RNA, Messenger; RNA, Small Interfering; Spinal Cord	2005
Distinct inhibition of voltage-activated Ca2+ channels by delta-opioid agonists in dorsal root ganglion neurons devoid of functional T-type Ca2+ currents. Neuroscience, 2008, Jun-02, Volume: 153, Issue:4 Topics: Analgesics, Opioid; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Ganglia, Spinal; Glycoproteins; Lectins; Male; Membrane Potentials; Naltrexone; Narcotic Antagonists; Neural Inhibition; Neurons, Afferent; Oligopeptides; omega-Conotoxin GVIA; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Versicans	2008
Removing TRPV1-expressing primary afferent neurons potentiates the spinal analgesic effect of delta-opioid agonists on mechano-nociception. Neuropharmacology, 2008, Volume: 55, Issue:2 Topics: Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Diterpenes; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Gene Expression Regulation; Hyperalgesia; Male; Naltrexone; Oligopeptides; Pain Threshold; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Sensory Receptor Cells; Spinal Cord; Tritium; TRPV Cation Channels	2008
[Analysis of central mechanisms involved in gastric mucosal integrity]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2008, Volume: 10, Issue:3 Topics: Animals; Arachidonic Acids; beta-Endorphin; Clonidine; Endocannabinoids; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Excitatory Amino Acids; Gastric Mucosa; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nociceptin; Oligopeptides; Opioid Peptides; Oxazoles; Polyunsaturated Alkamides; Rats; Rats, Wistar; Receptors, Opioid; Rilmenidine; Stomach Ulcer	2008
Blockade of central delta-opioid receptors inhibits salt appetite in sodium-depleted rats. Peptides, 2014, Volume: 55 Topics: Animals; Appetite; Blood Pressure; Drinking Behavior; Injections, Intraventricular; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Oligopeptides; Rats, Wistar; Receptors, Opioid, delta; Sodium; Sodium Chloride, Dietary	2014
Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro. Brain research bulletin, 2015, Volume: 110 Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Hot Temperature; Hyperalgesia; Lumbar Vertebrae; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Pain, Postoperative; Piperidines; Posterior Horn Cells; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Remifentanil; Spinal Cord; Tissue Culture Techniques; Touch	2015
Primary afferent neurons express functional delta opioid receptors in inflamed skin. Brain research, 2015, Jul-21, Volume: 1614 Topics: Action Potentials; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Freund's Adjuvant; Inflammation; Male; Naltrexone; Narcotic Antagonists; Nerve Fibers; Neurons, Afferent; Oligopeptides; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Skin	2015