Page last updated: 2024-09-03

deltorphin ii, ala(2)- and enkephalin, methionine

deltorphin ii, ala(2)- has been researched along with enkephalin, methionine in 9 studies

Compound Research Comparison

Studies
(deltorphin ii, ala(2)-)
Trials
(deltorphin ii, ala(2)-)
Recent Studies (post-2010)
(deltorphin ii, ala(2)-)
Studies
(enkephalin, methionine)
Trials
(enkephalin, methionine)
Recent Studies (post-2010) (enkephalin, methionine)
6022308
2330204,43945225

Protein Interaction Comparison

ProteinTaxonomydeltorphin ii, ala(2)- (IC50)enkephalin, methionine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.013
Delta-type opioid receptorRattus norvegicus (Norway rat)0.129
Mu-type opioid receptorRattus norvegicus (Norway rat)0.129
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.129
Mu-type opioid receptorHomo sapiens (human)0.013
Delta-type opioid receptorHomo sapiens (human)0.0064

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's5 (55.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L1
Haaseth, RC; Horan, P; Hruby, VJ; Matsunaga, TO; Porreca, F; Tallarida, RJ1
Tseng, LF; Wang, HQ; Xu, JY1
Mizoguchi, H; Nagase, H; Narita, M; Tseng, LF1
Elde, RP; Hauser, KF; Houdi, AA; Maxson, W; Turbek, CS1
Caffrey, JL; Farias, M; Jackson, KE; Yoshishige, D1
Christie, MJ; Connor, M; Marinelli, S; Schnell, SA; Vaughan, CW; Wessendorf, MW1
Barlow, MA; Caffrey, JL; Deo, SH; Johnson-Davis, S; Yoshishige, D1
Beaudet, A; Cahill, CM; Devi, LA; Esdaile, MJ; Gendron, L; Mennicken, F; O'Donnell, D; Pan, H; Stroh, T; Vincent, JP1

Other Studies

9 other study(ies) available for deltorphin ii, ala(2)- and enkephalin, methionine

ArticleYear
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software

1994
Antinociceptive interactions of opioid delta receptor agonists with morphine in mice: supra- and sub-additivity.
    Life sciences, 1992, Volume: 50, Issue:20

    Topics: Analgesics; Animals; Drug Synergism; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Male; Mice; Mice, Inbred ICR; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta

1992
Inhibition of spinal nitric oxide synthase by N(omega)-nitro-L-arginine blocks the release of Met-enkephalin and antinociception induced by supraspinally administered beta-endorphin in the rat.
    Neuroscience, 1997, Volume: 78, Issue:2

    Topics: Analgesics; Animals; beta-Endorphin; Enkephalin, Methionine; Enzyme Inhibitors; Injections, Intraventricular; Injections, Spinal; Male; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord

1997
Use of antisense oligodeoxynucleotide to delta-opioid receptor mRNA in the study of turnover of delta-opioid receptors in the spinal cord of the mouse.
    Psychopharmacology, 1997, Volume: 133, Issue:4

    Topics: Animals; Enkephalin, Methionine; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Oligonucleotides, Antisense; Oligopeptides; Pain Measurement; Protease Inhibitors; Receptors, Opioid, delta; RNA, Messenger; Spinal Cord; Thiorphan

1997
Opioids intrinsically inhibit the genesis of mouse cerebellar granule neuron precursors in vitro: differential impact of mu and delta receptor activation on proliferation and neurite elongation.
    The European journal of neuroscience, 2000, Volume: 12, Issue:4

    Topics: Analgesics, Opioid; Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Cerebellum; DNA; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Mice; Microscopy, Electron; Morphine; Naloxone; Narcotic Antagonists; Neurites; Neurons; Oligopeptides; Opioid-Related Disorders; Protein Precursors; Receptors, Opioid, delta; Receptors, Opioid, mu; Stem Cells

2000
Cardiac enkephalins interrupt vagal bradycardia via delta 2-opioid receptors in sinoatrial node.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Naltrexone; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Vagus Nerve

2003
delta-opioid receptor-mediated actions on rostral ventromedial medulla neurons.
    Neuroscience, 2005, Volume: 132, Issue:2

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Benzeneacetamides; Calcium Channels; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Immunohistochemistry; In Vitro Techniques; Lysine; Male; Medulla Oblongata; Membrane Potentials; Narcotic Antagonists; Neurons; Oligopeptides; Patch-Clamp Techniques; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Serotonin; Substance P; Tryptophan Hydroxylase

2005
Repeated delta1-opioid receptor stimulation reduces delta2-opioid receptor responses in the SA node.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Animals; Benzylidene Compounds; Bradycardia; Dogs; Dose-Response Relationship, Drug; Enkephalin, Methionine; Female; Male; Microdialysis; Naltrexone; Narcotic Antagonists; Oligopeptides; Quinolines; Receptors, Opioid, delta; Sinoatrial Node; Stimulation, Chemical; Vagus Nerve

2006
Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin.
    Neuroscience, 2007, Jan-05, Volume: 144, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Chronic Disease; Dose-Response Relationship, Drug; Enkephalin, Methionine; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Morphine; Oligopeptides; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Cell Surface; Receptors, Opioid, delta; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Up-Regulation

2007