deltorphin ii, ala(2)- has been researched along with enkephalin, leucine-2-alanine in 18 studies
| Studies (deltorphin ii, ala(2)-) | Trials (deltorphin ii, ala(2)-) | Recent Studies (post-2010) (deltorphin ii, ala(2)-) | Studies (enkephalin, leucine-2-alanine) | Trials (enkephalin, leucine-2-alanine) | Recent Studies (post-2010) (enkephalin, leucine-2-alanine) |
|---|---|---|---|---|---|
| 6 | 0 | 2 | 1,581 | 23 | 74 |
| 233 | 0 | 20 | 1,581 | 23 | 74 |
| Protein | Taxonomy | deltorphin ii, ala(2)- (IC50) | enkephalin, leucine-2-alanine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0915 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0017 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.009 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0419 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 1.4691 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.009 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, GI; Chen, Y; Kong, H; Raynor, K; Reisine, T; Yasuda, K; Yu, L | 1 |
| Adapa, ID; Auh, JS; Berzetei-Gurske, IP; Brandt, SR; Craymer, K; Farrington, L; Haggart, D; Kennedy, JM; O'Brien, A; Polgar, WE; Rodriguez, L; Schwartz, RW; Toll, L; White, A | 1 |
| Bowen, WD; Farmer, SC; Mattia, A; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE | 1 |
| Bowen, WD; Jiang, Q; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE | 1 |
| Ambo, A; Sasaki, Y; Suzuki, K | 1 |
| Jacobson, AE; Ni, Q; Rice, KC; Rothman, RB; Xu, H | 1 |
| Burks, TF; Davis, P; Haaseth, RC; Hruby, VJ; Kramer, TH; Matsunaga, TO; Toth, G | 1 |
| Castro, MA; Garzón, J; Juarros, JL; Sánchez-Blázquez, P | 1 |
| Haaseth, RC; Hruby, VJ; Matsunaga, TO; Mosberg, HI; Porreca, F; Portoghese, PS; Sultana, M; Takemori, AE; Vanderah, T | 1 |
| Darula, Z; Fürst, S; Gyires, K; Rónai, AZ; Tóth, G | 1 |
| Carroll, J; Chan, KW; Chen, BT; Duttaroy, A; Philippe, J; Sehba, F; Shen, J; Yoburn, BC | 1 |
| DeAntonio, I; DeFelipe, J; García-España, A; Garzón, J; Rodríguez, JR; Sánchez-Blázquez, P | 1 |
| Gyires, K; Rónai, AZ | 1 |
| Geĭn, SV; Gorshkova, KG; Tendriakova, SP | 1 |
| Ananth, S; Ganapathy, V; Hooks, JJ; Karunakaran, S; Martin, PM; Nagineni, CN; Prasad, PD; Smith, SB | 1 |
| Gein, SV; Gorshkova, KG; Tendryakova, SP | 1 |
| Chothe, P; Ganapathy, V; Singh, N | 1 |
| Ananth, S; Ganapathy, PS; Ganapathy, V; Gnana-Prakasam, JP; Martin, PM; Smith, SB; Thakkar, SV | 1 |
18 other study(ies) available for deltorphin ii, ala(2)- and enkephalin, leucine-2-alanine
| Article | Year |
|---|---|
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Topics: Analgesics; Animals; Binding Sites; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Ligands; PC12 Cells; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Software | 1994 |
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
Topics: Animals; Aorta, Thoracic; Cocaine; Cyclic AMP; Electric Stimulation; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Opioid-Related Disorders; Rats; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin; Substance-Related Disorders | 1998 |
Spinal opioid delta antinociception in the mouse: mediation by a 5'-NTII-sensitive delta receptor subtype.
Topics: Affinity Labels; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Receptors, Opioid, delta; Spinal Cord; Thiocyanates | 1992 |
Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Morphinans; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Thiocyanates | 1991 |
[D-Ala2]deltorphin II analogs with high affinity and selectivity for delta-opioid receptor.
Topics: Animals; Brain; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Synaptosomes | 1991 |
Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Molecular Sequence Data; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin | 1991 |
Influence of peptidase inhibitors on the apparent agonist potency of delta selective opioid peptides in vitro.
Topics: Amino Acid Sequence; Analgesics; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligopeptides; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens | 1991 |
Antibodies raised against the N-terminal sequence of delta opioid receptors blocked delta-mediated supraspinal antinociception in mice.
Topics: Amino Acid Sequence; Analysis of Variance; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; GTP-Binding Proteins; Immunoglobulin G; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Morphine; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Protein Binding; Reaction Time; Receptors, Opioid, delta | 1994 |
Interaction of [D-Pen2,D-Pen5]enkephalin and [D-Ala2,Glu4]deltorphin with delta-opioid receptor subtypes in vivo.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Isothiocyanates; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Naltrexone; Oligopeptides; Pain Measurement; Reaction Time; Receptors, Opioid, delta | 1994 |
Analysis of the role of delta opioid receptors in gastroprotection in the rat.
Topics: Analgesics; Animals; Binding Sites; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethanol; Gastric Mucosa; Ileum; Male; Mice; Mice, Inbred Strains; Morphine; Muscle, Smooth; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach; Stomach Diseases; Vas Deferens | 1997 |
The effect of in vivo ethanol consumption on cyclic AMP and delta-opioid receptors in mouse striatum.
Topics: Animals; Binding, Competitive; Central Nervous System Depressants; Colforsin; Corpus Striatum; Cyclic AMP; Enkephalin, Leucine-2-Alanine; Ethanol; Gene Expression Regulation; Male; Mice; Oligopeptides; Receptors, Opioid, delta; RNA, Messenger; Signal Transduction; Time Factors; Tritium | 1997 |
Transport of CSF antibodies to Galpha subunits across neural membranes requires binding to the target protein and protein kinase C activity.
Topics: Analgesics; Analgesics, Opioid; Animals; Autoantibodies; Biological Transport; Brain Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Epitopes; GTP-Binding Protein alpha Subunits, Gi-Go; Immunoblotting; Immunoglobulin G; Injections, Intraventricular; Iodine Radioisotopes; Male; Mice; Mice, Inbred Strains; Microscopy, Immunoelectron; Morphine; Neurons; Nociceptors; Oligopeptides; Pain; Protein Kinase C; Signal Transduction | 1999 |
Supraspinal delta- and mu-opioid receptors mediate gastric mucosal protection in the rat.
Topics: Animals; beta-Endorphin; Brain; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Hydrochloric Acid; Male; Narcotic Antagonists; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Stomach Ulcer; Vagotomy | 2001 |
[Regulation of IL-1beta and IL-8 production by mu-, delta-opiate receptors agonists in vitro].
Topics: Adult; beta-Endorphin; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Humans; Interleukin-1beta; Interleukin-8; Leukocytes; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Neutrophils; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu | 2008 |
Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE.
Topics: Amiloride; Animals; Biological Transport; Cell Line; Conjunctiva; Enkephalin, Leucine-2-Alanine; Epithelial Cells; Naloxone; Oligopeptides; Opioid Peptides; Organic Anion Transporters; Rabbits; Sodium-Potassium-Exchanging ATPase | 2009 |
Regulation of interleukin-1beta and interleukin-8 production by agonists of mu and delta opiate receptors in vitro.
Topics: Adult; beta-Endorphin; Cells, Cultured; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Humans; Interleukin-1beta; Interleukin-8; Leukocytes; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Neutrophils; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu | 2009 |
Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841.
Topics: Biological Transport; Caco-2 Cells; Cell Line; Colon; Enkephalin, Leucine-2-Alanine; Humans; Membrane Transport Proteins; Oligopeptides | 2011 |
Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells.
Topics: Amino Acids; Animals; Biological Transport; Cell Line; Enkephalin, Leucine-2-Alanine; Kinetics; Membrane Transport Proteins; Mice; Oligopeptides; Opioid Peptides; Retinal Ganglion Cells; Sodium; Substrate Specificity | 2012 |