deltorphin i, ala(2)- has been researched along with naltrindole in 12 studies
| Studies (deltorphin i, ala(2)-) | Trials (deltorphin i, ala(2)-) | Recent Studies (post-2010) (deltorphin i, ala(2)-) | Studies (naltrindole) | Trials (naltrindole) | Recent Studies (post-2010) (naltrindole) |
|---|---|---|---|---|---|
| 122 | 0 | 4 | 801 | 0 | 139 |
| Protein | Taxonomy | deltorphin i, ala(2)- (IC50) | naltrindole (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0007 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0006 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (66.67) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chung, NN; Lemieux, C; Nguyen, TM; Schiller, PW; Weltrowska, G; Wilkes, BC | 1 |
| Balboni, G; Bianchi, C; Bryant, SD; Cooper, PS; Guerrini, R; Lazarus, LH; Salvadori, S; Tomatis, R | 1 |
| Broeck, JV; Chung, NN; Costentin, J; do-Rego, JC; Fichna, J; Janecka, A; Lemieux, C; Poels, J; Schiller, PW | 1 |
| Bernard, D; Coop, A; MacKerell, AD | 1 |
| Crook, TJ; Hill, RG; Kitchen, I | 1 |
| Angelucci, F; Negri, L; Noviello, V | 1 |
| Mokhtari, M; Tafani, JA; Zajac, JM | 1 |
| Capobianchi, MR; Negri, L; Noviello, L; Papadia, S | 1 |
| Desprat, C; Zajac, JM | 1 |
| Borsodi, A; Hill, RG; Kelly, MD; Kitchen, I; Toth, G | 1 |
| Kieffer, BL; Maldonado, R; Matthes, HW; Melchiorri, P; Negri, L; Severini, C | 1 |
| Balboni, G; Jinsmaa, Y; Lazarus, LH; Marczak, ED; Salvadori, S | 1 |
12 other study(ies) available for deltorphin i, ala(2)- and naltrindole
| Article | Year |
|---|---|
TIPP[psi]: a highly potent and stable pseudopeptide delta opioid receptor antagonist with extraordinary delta selectivity.
Topics: Animals; Binding Sites; Guinea Pigs; Male; Mice; Molecular Conformation; Oligopeptides; Receptors, Opioid, delta; Tetrahydroisoquinolines | 1993 |
Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
Topics: Animals; Binding, Competitive; Cell Membrane; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Isoquinolines; Kinetics; Male; Methylation; Mice; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 1997 |
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2).
Topics: Aequorin; Analgesics; Animals; Binding Sites; Brain; Calcium; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Ileum; In Vitro Techniques; Luminescent Agents; Male; Mice; Muscle Contraction; Muscle, Smooth; Oligopeptides; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Vas Deferens | 2007 |
Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity.
Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta | 2007 |
Effects of the delta-opioid receptor antagonist naltrindole on antinociceptive responses to selective delta-agonists in post-weanling rats.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta | 1992 |
Behavioural effects of deltorphins in rats.
Topics: Analgesics; Animals; Behavior, Animal; Indoles; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Social Behavior; Stereotyped Behavior | 1991 |
Binding in vivo of selective mu and delta opioid agonists: localization by autoradiography.
Topics: Amino Acid Sequence; Analgesics; Animals; Autoradiography; Binding, Competitive; Brain; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Diffusion; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Male; Mice; Molecular Sequence Data; Naltrexone; Oligopeptides; Pain Measurement; Protein Binding; Receptors, Opioid, delta; Receptors, Opioid, mu | 1993 |
Immunomodulatory responses to delta-opioid receptor ligands in human lymphocytes.
Topics: Analgesics, Opioid; Humans; Interferon-gamma; Leukocytes, Mononuclear; Ligands; Lymphocyte Activation; Naltrexone; Narcotic Antagonists; Oligopeptides; Phytohemagglutinins; Receptors, Opioid, delta; Thymidine | 1997 |
Differential modulation of mu- and delta-opioid antinociception by neuropeptide FF receptors in young mice.
Topics: Age Factors; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred Strains; Morphine; Naltrexone; Narcotic Antagonists; Neuropeptides; Nociceptors; Oligopeptides; Receptors, Neuropeptide; Receptors, Opioid, delta; Receptors, Opioid, mu | 1997 |
Weaning-induced development of delta-opioid receptors in rat brain: differential effects of guanine nucleotides and sodium upon ligand-receptor recognition.
Topics: Animals; Brain; Guanylyl Imidodiphosphate; In Vitro Techniques; Ligands; Naltrexone; Oligopeptides; Rats; Rats, Wistar; Receptors, Opioid, delta; Sodium; Weaning | 1998 |
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 2001 |
Inhibition of the development of morphine tolerance by a potent dual mu-delta-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph.
Topics: Analgesics, Opioid; Animals; Area Under Curve; Dose-Response Relationship, Drug; Drug Tolerance; Injections, Intraventricular; Injections, Subcutaneous; Ligands; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 2008 |