deltorphin i, ala(2)- has been researched along with naloxone in 7 studies
| Studies (deltorphin i, ala(2)-) | Trials (deltorphin i, ala(2)-) | Recent Studies (post-2010) (deltorphin i, ala(2)-) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 122 | 0 | 4 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | deltorphin i, ala(2)- (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broeck, JV; Chung, NN; Costentin, J; do-Rego, JC; Fichna, J; Janecka, A; Lemieux, C; Poels, J; Schiller, PW | 1 |
| Broeck, JV; Costentin, J; do-Rego, JC; Fichna, J; Janecka, A; Janecki, T; Poels, J; Schiller, PW; Staniszewska, R | 1 |
| Crook, TJ; Hill, RG; Kitchen, I | 1 |
| Angelucci, F; Negri, L; Noviello, V | 1 |
| Cridland, R; Cros, J; Gouarderes, C; Jhamandas, K; Quirion, R; Zajac, JM | 1 |
| Allouche, S; Jauzac, P; Marie, N; Roussel, M | 1 |
| Cui, SG; Dai, X; Liu, Q; Song, HJ; Wang, R; Wang, T | 1 |
7 other study(ies) available for deltorphin i, ala(2)- and naloxone
| Article | Year |
|---|---|
Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2).
Topics: Aequorin; Analgesics; Animals; Binding Sites; Brain; Calcium; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Ileum; In Vitro Techniques; Luminescent Agents; Male; Mice; Muscle Contraction; Muscle, Smooth; Oligopeptides; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Vas Deferens | 2007 |
Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure.
Topics: Analgesics, Opioid; Animals; Calcium; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Drug Design; Mice; Oligopeptides; Pain Measurement; Protein Conformation; Receptors, Opioid, mu; Spectrometry, Mass, Fast Atom Bombardment | 2008 |
Effects of the delta-opioid receptor antagonist naltrindole on antinociceptive responses to selective delta-agonists in post-weanling rats.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta | 1992 |
Behavioural effects of deltorphins in rats.
Topics: Analgesics; Animals; Behavior, Animal; Indoles; Injections, Intraventricular; Male; Morphinans; Motor Activity; Naloxone; Naltrexone; Oligopeptides; Pain Measurement; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Social Behavior; Stereotyped Behavior | 1991 |
Opioid and substance P receptor adaptations in the rat spinal cord following sub-chronic intrathecal treatment with morphine and naloxone.
Topics: Analgesics; Animals; Autoradiography; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Densitometry; Drug Tolerance; In Vitro Techniques; Injections, Spinal; Male; Morphine; Naloxone; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Succinimides | 1993 |
Differential desensitization of human delta-opioid receptors by peptide and alkaloid agonists.
Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Analgesics; Analgesics, Opioid; Cyclic AMP; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; Humans; Naloxone; Neuroblastoma; Oligopeptides; Peptides; Receptors, Opioid, delta; Tumor Cells, Cultured | 1999 |
Endogenous opioid peptides, endomorphin-1 and -2 and deltorphin I, stimulate angiogenesis in the CAM assay.
Topics: Analgesics, Opioid; Animals; Chick Embryo; Chorioallantoic Membrane; Dose-Response Relationship, Drug; Naloxone; Narcotic Antagonists; Neovascularization, Physiologic; Oligopeptides; Receptors, Opioid, mu | 2008 |