deltorphin i, ala(2)- has been researched along with enkephalin, d-penicillamine (2,5)- in 19 studies
| Studies (deltorphin i, ala(2)-) | Trials (deltorphin i, ala(2)-) | Recent Studies (post-2010) (deltorphin i, ala(2)-) | Studies (enkephalin, d-penicillamine (2,5)-) | Trials (enkephalin, d-penicillamine (2,5)-) | Recent Studies (post-2010) (enkephalin, d-penicillamine (2,5)-) |
|---|---|---|---|---|---|
| 122 | 0 | 4 | 1,314 | 0 | 73 |
| Protein | Taxonomy | deltorphin i, ala(2)- (IC50) | enkephalin, d-penicillamine (2,5)- (IC50) |
|---|---|---|---|
| Mu-type opioid receptor | Homo sapiens (human) | 0.0016 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (63.16) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crook, TJ; Hill, RG; Kitchen, I | 1 |
| Corsi, R; Melchiorri, P; Negri, L; Potenza, RL | 1 |
| Jacobson, AE; Ni, Q; Rice, KC; Rothman, RB; Xu, H | 1 |
| Burks, TF; Davis, P; Haaseth, RC; Hruby, VJ; Kramer, TH; Matsunaga, TO; Toth, G | 1 |
| Bilsky, EJ; Davis, P; Horváth, R; Kövér, KE; Lou, BS; Misicka, A; Porreca, F; Qian, X; Shenderovich, MD; Zalewska, T | 1 |
| Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
| Amodeo, P; Bianchi, C; Guerrini, R; Lazarus, LH; Picone, D; Salvadori, S; Tancredi, T; Temussi, PA; Tomatis, R | 1 |
| Lattanzi, R; Melchiorri, P; Negri, L; Potenza, RL; Severini, C | 1 |
| Cavagnero, S; Davis, P; Horvath, R; Hruby, VJ; Misicka, A; Porreca, F; Yamamura, HI | 1 |
| Basbaum, AI; Hammond, DL; Nakashima, N; Wang, H | 1 |
| Allouche, S; Jauzac, P; Marie, N; Roussel, M | 1 |
| Allouche, S; Hasbi, A; Homburger, V; Jauzac, P; Polastron, J | 1 |
| Allouche, S; Ferey, V; Hasbi, A; Jauzac, P; Polastron, J; Sola, B | 1 |
| Bilsky, EJ; Hruby, VJ; Porreca, F; Qian, X | 1 |
| Kieffer, BL; Maldonado, R; Matthes, HW; Melchiorri, P; Negri, L; Severini, C | 1 |
| Allouche, S; Jauzac, P; Lecoq, I; Marie, N | 1 |
| Aguila, B; Allouche, S; Davis, A; Hasbi, A; Jauzac, P; Marie, N | 1 |
| Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H | 1 |
| Aguila, B; Allouche, S; Borsodi, A; Coulbault, L; Davis, A; Gurevich, VV; Hasbi, A; Jauzac, P; Le bras, F; Marie, N; Tóth, G | 1 |
19 other study(ies) available for deltorphin i, ala(2)- and enkephalin, d-penicillamine (2,5)-
| Article | Year |
|---|---|
Effects of the delta-opioid receptor antagonist naltrindole on antinociceptive responses to selective delta-agonists in post-weanling rats.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Male; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Opioid, delta | 1992 |
Evidence for two subtypes of delta opioid receptors in rat brain.
Topics: Animals; Binding, Competitive; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Kinetics; Male; Membranes; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta | 1991 |
Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Molecular Sequence Data; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin | 1991 |
Influence of peptidase inhibitors on the apparent agonist potency of delta selective opioid peptides in vitro.
Topics: Amino Acid Sequence; Analgesics; Animals; Dose-Response Relationship, Drug; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligopeptides; Protease Inhibitors; Receptors, Opioid; Receptors, Opioid, delta; Vas Deferens | 1991 |
Newly discovered stereochemical requirements in the side-chain conformation of delta opioid agonists for recognizing opioid delta receptors.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Molecular Sequence Data; Oligopeptides; Peptides; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Stereoisomerism; Structure-Activity Relationship | 1994 |
Streptozotocin-induced diabetes selectively enhances antinociception mediated by delta 1- but not delta 2-opioid receptors.
Topics: Analgesia; Animals; Benzylidene Compounds; Diabetes Mellitus, Experimental; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Streptozocin | 1994 |
Selective opioid dipeptides.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Cell Membrane; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Isoquinolines; Kinetics; Models, Molecular; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Narcotics; Oligopeptides; Protein Conformation; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Synaptosomes; Tetrahydroisoquinolines | 1994 |
Postnatal development of delta-opioid receptor subtypes in mice.
Topics: Animals; Animals, Suckling; Brain; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Receptors, Opioid, delta; Vas Deferens | 1997 |
Synthesis and biological properties of beta-MePhe3 analogues of deltorphin I and dermenkephalin: influence of biased chi 1 Phe3 residues on peptide recognition for delta-opioid receptors.
Topics: Aminobutyrates; Analgesics, Opioid; Animals; Binding, Competitive; Brain; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oligopeptides; Protein Binding; Protein Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Stereoisomerism | 1997 |
Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Formaldehyde; Male; Oligopeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1998 |
Differential desensitization of human delta-opioid receptors by peptide and alkaloid agonists.
Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Analgesics; Analgesics, Opioid; Cyclic AMP; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; Humans; Naloxone; Neuroblastoma; Oligopeptides; Peptides; Receptors, Opioid, delta; Tumor Cells, Cultured | 1999 |
Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Animals; Azides; Cell Membrane; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Isoelectric Point; Neuroblastoma; Neurons; Oligodeoxyribonucleotides, Antisense; Oligopeptides; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
Pharmacological delta1- and delta2-opioid receptor subtypes in the human neuroblastoma cell line SK-N-BE: no evidence for distinct molecular entities.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Binding, Competitive; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Humans; Neuroblastoma; Oligopeptides; Receptors, Opioid, delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Antinociceptive activity of [beta-methyl-2', 6'-dimethyltyrosine(1)]-substituted cyclic [D-Pen(2), D-Pen(5)]Enkephalin and [D-Ala(2),Asp(4)]Deltorphin analogs.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Oligopeptides; Pain Measurement; Peptides, Cyclic; Receptors, Opioid; Time Factors | 2000 |
Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Female; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Morphine; Muscle Contraction; Naltrexone; Narcotic Antagonists; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 2001 |
Differential sorting of human delta-opioid receptors after internalization by peptide and alkaloid agonists.
Topics: Alkaloids; Analgesics, Opioid; Down-Regulation; Endosomes; Enkephalin, D-Penicillamine (2,5)-; Etorphine; Humans; Kinetics; Oligopeptides; Peptides; Receptors, Opioid, delta; Recombinant Proteins; Transfection | 2003 |
Different kinases desensitize the human delta-opioid receptor (hDOP-R) in the neuroblastoma cell line SK-N-BE upon peptidic and alkaloid agonists.
Topics: Analgesics, Opioid; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Enkephalin, D-Penicillamine (2,5)-; Etorphine; G-Protein-Coupled Receptor Kinase 2; Humans; Mutation; Neuroblastoma; Oligopeptides; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Receptors, Opioid, delta | 2008 |
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands.
Topics: Arrestins; beta-Arrestins; Cell Line; Endocytosis; Enkephalin, D-Penicillamine (2,5)-; Etorphine; Humans; Ligands; Oligopeptides; Receptors, Opioid, delta; RNA Interference; RNA, Small Interfering; Signal Transduction | 2012 |