deltorphin i, ala(2)- has been researched along with dermorphin in 13 studies
| Studies (deltorphin i, ala(2)-) | Trials (deltorphin i, ala(2)-) | Recent Studies (post-2010) (deltorphin i, ala(2)-) | Studies (dermorphin) | Trials (dermorphin) | Recent Studies (post-2010) (dermorphin) |
|---|---|---|---|---|---|
| 122 | 0 | 4 | 401 | 2 | 39 |
| Protein | Taxonomy | deltorphin i, ala(2)- (IC50) | dermorphin (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0389 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0043 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0018 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.2492 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0086 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 7 (53.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lazarus, LH; Salvadori, S; Santagada, V; Tomatis, R; Wilson, WE | 1 |
| Balboni, G; Caliendo, G; Capasso, A; Guerrini, R; Lazarus, LH; Marastoni, M; Salvadori, S; Santagada, V; Sorrentino, L; Tomatis, R | 1 |
| Balboni, G; Bianchi, C; Bryant, SD; Cooper, PS; Guerrini, R; Lazarus, LH; Salvadori, S; Tomatis, R | 1 |
| Lattanzi, R; Negri, L; Orrù, L; Rocchi, R; Scolaro, B; Severini, C; Tabacco, F | 1 |
| Balboni, G; Bianchi, C; Bryant, SD; Guerrini, R; Lazarus, LH; Rizzi, D; Salvadori, S | 1 |
| Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Sasaki, Y; Yamamoto, Y | 1 |
| Carr, DB; Kosson, P; Lipkowski, AW; Ronsisvalle, G; Sperlinga, E; Urbanczyk-Lipkowska, Z | 1 |
| Balboni, G; Bryant, SD; Giannini, E; Guerrini, R; Jinsmaa, Y; Lazarus, LH; Negri, L; Salvadori, S | 1 |
| Corsi, R; Egger, R; Kreil, G; Negri, L; Richter, K; Severini, C | 1 |
| Doi, M; Ishida, T; Iwashita, T; Ohno, Y; Segawa, M | 1 |
| Campana, G; Capasso, A; Galietta, G; Loizzo, A; Severini, C; Spampinato, S | 1 |
| Biondi, L; Filira, F; Giannini, E; Gobbo, M; Marastoni, M; Negri, L; Rocchi, R; Scolaro, B; Tomatisc, R | 1 |
| Ejchart, A; Kosson, P; Kwasiborska, M; Olma, A; Wilczyńska, D | 1 |
13 other study(ies) available for deltorphin i, ala(2)- and dermorphin
| Article | Year |
|---|---|
Function of negative charge in the "address domain" of deltorphins.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, Leucine-2-Alanine; Oligopeptides; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 1991 |
Synthesis and pharmacological activity of deltorphin and dermorphin-related glycopeptides.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glycopeptides; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Jejunum; Kinetics; Male; Mice; Muscle Contraction; Muscle, Smooth; Oligopeptides; Opioid Peptides; Pain; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Structure-Activity Relationship; Synaptosomes | 1997 |
Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity.
Topics: Animals; Binding, Competitive; Cell Membrane; Dipeptides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Isoquinolines; Kinetics; Male; Methylation; Mice; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship; Vas Deferens | 1997 |
Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Glycosylation; Guinea Pigs; In Vitro Techniques; Injections, Subcutaneous; Male; Mice; Muscle, Smooth; Oligopeptides; Opioid Peptides; Receptors, Opioid | 1999 |
Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties.
Topics: Animals; Brain; Dipeptides; In Vitro Techniques; Ligands; Male; Mice; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Synaptosomes; Tetrahydroisoquinolines; Vas Deferens | 2002 |
Dermorphin and deltorphin heptapeptide analogues: replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity.
Topics: Analgesics, Opioid; Animals; Guinea Pigs; Inhibitory Concentration 50; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Phenylalanine; Protein Binding; Receptors, Opioid; Structure-Activity Relationship | 2002 |
6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides.
Topics: Carboxylic Acids; Crystallography, X-Ray; Isoquinolines; Molecular Structure; Opioid Peptides; Receptors, Opioid; Tyrosine | 2005 |
Conversion of the potent delta-opioid agonist H-Dmt-Tic-NH-CH(2)-bid into delta-opioid antagonists by N(1)-benzimidazole alkylation(1).
Topics: Alkylation; Animals; Benzimidazoles; Dipeptides; Guinea Pigs; Ileum; Inhibitory Concentration 50; Male; Mice; Rats; Receptors, Opioid, delta; Synaptosomes; Vas Deferens | 2005 |
cDNAs encoding [D-Ala2]deltorphin precursors from skin of Phyllomedusa bicolor also contain genetic information for three dermorphin-related opioid peptides.
Topics: Amino Acid Sequence; Animals; Anura; Base Sequence; Colon; DNA; Guinea Pigs; In Vitro Techniques; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Oligopeptides; Opioid Peptides; Protein Precursors; Sequence Homology, Nucleic Acid; Skin | 1990 |
Solution conformation of mu-selective dermorphin and delta-selective deltorphin-I in phospholipid micelles, studied by NMR spectroscopy and molecular dynamics simulations.
Topics: Amino Acid Sequence; Liposomes; Magnetic Resonance Spectroscopy; Micelles; Molecular Sequence Data; Oligopeptides; Opioid Peptides; Phosphorylcholine; Protein Conformation; Protons; Receptors, Opioid; Solutions | 1995 |
Vas deferens response to selective opioid receptor agonists in adult mice is impaired following postnatal repeated mild stress.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Dynorphins; Female; Humans; Male; Mice; Mutation; Oligonucleotides, Antisense; Oligopeptides; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Physiological; Time Factors; Vas Deferens | 2003 |
Synthesis, conformation and biological activity of dermorphin and deltorphin I analogues containing N-alkylglycine in place of residues in position 1, 3, 5 and 6.
Topics: Analgesics, Opioid; Animals; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Male; Mice; Muscle Contraction; Muscle, Smooth; N-substituted Glycines; Oligopeptides; Opioid Peptides; Pain; Protein Conformation; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu | 2003 |
Synthesis and receptor binding of opioid peptide analogues containing beta3-homo-amino acids.
Topics: Enkephalin, Leucine; Magnetic Resonance Spectroscopy; Molecular Structure; Oligopeptides; Opioid Peptides; Protein Binding; Receptors, Opioid; Receptors, Opioid, mu; Receptors, sigma; Structure-Activity Relationship | 2009 |