Page last updated: 2024-09-03

deltorphin i, ala(2)- and bw 373u86

deltorphin i, ala(2)- has been researched along with bw 373u86 in 2 studies

Compound Research Comparison

Studies (deltorphin i, ala(2)-)	Trials (deltorphin i, ala(2)-)	Recent Studies (post-2010) (deltorphin i, ala(2)-)	Studies (bw 373u86)	Trials (bw 373u86)	Recent Studies (post-2010) (bw 373u86)
122	0	4	80	0	4

Protein Interaction Comparison

Protein	Taxonomy	bw 373u86 (IC50)
Delta-type opioid receptor	Rattus norvegicus (Norway rat)	0.02
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	0.9346
Mu-type opioid receptor	Homo sapiens (human)	0.0021
Delta-type opioid receptor	Homo sapiens (human)	0.0002
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	0.0003
Kappa-type opioid receptor	Homo sapiens (human)	0.02

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Becketts, K; Bilsky, EJ; Calderon, SN; Davis, P; Flippen-Anderson, JL; Horvath, R; Kayakiri, H; Porreca, F; Rice, KC; Rothman, RB; Smith, LE; Xu, H	1
Bernard, D; Coop, A; MacKerell, AD	1

Other Studies

2 other study(ies) available for deltorphin i, ala(2)- and bw 373u86

Article	Year
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80) Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5 Topics: Animals; Benzamides; Binding, Competitive; Brain; Crystallography, X-Ray; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens	1997
Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity. Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8 Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta	2007

Article

Year

Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80)

Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5

Topics: Animals; Benzamides; Binding, Competitive; Brain; Crystallography, X-Ray; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens

1997

Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity.

Journal of medicinal chemistry, 2007, Apr-19, Volume: 50, Issue:8

Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta

2007