deltorphin i, ala(2)- has been researched along with 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide in 3 studies
| Studies (deltorphin i, ala(2)-) | Trials (deltorphin i, ala(2)-) | Recent Studies (post-2010) (deltorphin i, ala(2)-) | Studies (4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide) | Trials (4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide) | Recent Studies (post-2010) (4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide) |
|---|---|---|---|---|---|
| 122 | 0 | 4 | 279 | 0 | 85 |
| Protein | Taxonomy | deltorphin i, ala(2)- (IC50) | 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0842 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0879 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 4.7722 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 3.601 | |
| Mu-type opioid receptor | Homo sapiens (human) | 1.8083 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0086 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 3.85 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 2.48 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 6.066 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 10 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becketts, K; Bilsky, EJ; Calderon, SN; Davis, P; Flippen-Anderson, JL; Horvath, R; Kayakiri, H; Porreca, F; Rice, KC; Rothman, RB; Smith, LE; Xu, H | 1 |
| Bernard, D; Coop, A; MacKerell, AD | 1 |
| Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H | 1 |
3 other study(ies) available for deltorphin i, ala(2)- and 4-(alpha-(4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl)-n,n-diethylbenzamide
| Article | Year |
|---|---|
Probes for narcotic receptor mediated phenomena. 23. Synthesis, opioid receptor binding, and bioassay of the highly selective delta agonist (+)-4-[(alpha R)-alpha-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]- N,N-diethylbenzamide (SNC 80)
Topics: Animals; Benzamides; Binding, Competitive; Brain; Crystallography, X-Ray; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Vas Deferens | 1997 |
Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity.
Topics: Animals; Cell Line, Tumor; Enkephalin, Leucine; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Quantitative Structure-Activity Relationship; Rats; Receptors, Opioid, delta | 2007 |
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |