deltakephalin has been researched along with morphine in 20 studies
| Studies (deltakephalin) | Trials (deltakephalin) | Recent Studies (post-2010) (deltakephalin) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 79 | 0 | 0 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | deltakephalin (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 10 (50.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Besse, D; Besson, JM; Lombard, MC | 1 |
| Bing, Z; Bouhassira, D; Le Bars, D; Villanueva, L | 1 |
| Layer, RT; Uretsky, NJ; Wallace, LJ | 1 |
| Kaneto, H; Shiigi, Y; Takahashi, M | 1 |
| Cesselin, F; Hamon, M; Legrand, JC; Lutz, O; Mauborgne, A | 1 |
| Delay-Goyet, P; Meucci, E; Roques, BP; Zajac, JM | 1 |
| Farges, RC; Meunier, JC; Moisand, C; Puget, A | 1 |
| Blanchard, JC; Böhme, GA; Roques, BP; Stutzmann, JM | 2 |
| Heyman, JS; Mosberg, HI; Omnaas, JR; Porreca, F; Vaught, JL | 1 |
| Burks, TF; Hruby, VJ; Hurst, R; Mosberg, HI; Porreca, F | 1 |
| Jauzac, P; Polastron, J | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Legrand, JC; Mauborgne, A | 1 |
| Bourgoin, S; Cesselin, F; Collin, E; Frechilla, D; Hamon, M; Le Bars, D; Pohl, M | 1 |
| Dupouy, V; Zajac, JM | 1 |
| Catheline, G; Guilbaud, G; Idänpään-Heikkilä, JJ; Kayser, V | 1 |
| Kramer, HK; Simon, EJ | 1 |
| Jinsmaa, Y; Takahashi, M; Yoshikawa, M | 1 |
| Jinsmaa, Y; Lipkowski, AW; Nakamura, F; Takenaka, Y; Yoshikawa, M | 1 |
20 other study(ies) available for deltakephalin and morphine
| Article | Year |
|---|---|
Up-regulation of [3H]DAMGO and [3H]DTLET opioid binding sites in laminae I-II of the spinal cord in intact and deafferented morphine-tolerant rats.
Topics: Animals; Autoradiography; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Morphine; Neurons, Afferent; Oligopeptides; Rats; Receptors, Opioid; Spinal Cord; Up-Regulation | 1992 |
Depressive effects of mu and delta opioid receptor agonists on activities of dorsal horn neurones are enhanced by dibencozide.
Topics: Amino Acid Sequence; Analgesics; Animals; Cobamides; Depression, Chemical; Drug Interactions; Male; Molecular Sequence Data; Morphine; Nerve Fibers; Neurons; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1991 |
Effects of morphine in the nucleus accumbens on stimulant-induced locomotion.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Caffeine; Central Nervous System Stimulants; Dizocilpine Maleate; Dopamine Agents; Glutamine; Ibotenic Acid; Male; Morphine; Motor Activity; Neural Pathways; Nucleus Accumbens; Oligopeptides; Picrotoxin; Rats; Scopolamine; Synaptic Transmission | 1991 |
Facilitation of memory retrieval by pretest morphine mediated by mu but not delta and kappa opioid receptors.
Topics: Analgesics; Animals; Avoidance Learning; Benzeneacetamides; Electroshock; Male; Memory; Mice; Mice, Inbred Strains; Morphine; Naloxone; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1990 |
Opposite effects of delta and mu opioid receptor agonists on the in vitro release of substance P-like material from the rat spinal cord.
Topics: Animals; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; In Vitro Techniques; Male; Morphine; Naloxone; Oligopeptides; Potassium; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tetrodotoxin; Veratridine | 1987 |
Binding in vivo of selective mu and delta opioid receptor agonists: opioid receptor occupancy by endogenous enkephalins.
Topics: Animals; Brain; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydroxamic Acids; In Vitro Techniques; Injections; Kinetics; Male; Mice; Morphine; Oligopeptides; Phenylalanine; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Thiorphan | 1989 |
Opioid receptor types in the brain of the Afghan pika (Ochotona rufescens), a species which is naturally tolerant to morphine.
Topics: Animals; Binding, Competitive; Brain Chemistry; Diprenorphine; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanylyl Imidodiphosphate; Lagomorpha; Membranes; Morphine; Oligopeptides; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1988 |
Differential electrographic patterns for specific mu- and delta-opioid peptides in rats.
Topics: Animals; Electroencephalography; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Epilepsy; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1986 |
Role of mu and delta receptors in the supraspinal and spinal analgesic effects of [D-Pen2, D-Pen5]enkephalin in the mouse.
Topics: Analgesia; Anesthesia, Spinal; Animals; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Male; Mice; Morphine; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Effects of selective mu- and delta-opioid peptides on kindled amygdaloid seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Kindling, Neurologic; Male; Morphine; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1987 |
Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Animals; Digestive System Physiological Phenomena; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hot Temperature; Injections, Intraventricular; Injections, Spinal; Male; Mice; Morphine; Narcotics; Oligopeptides; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1984 |
Different subtypes of opioid receptors have different affinities for G-proteins.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1994 |
Morphine reduces the release of met-enkephalin-like material from the rat spinal cord in vivo by acting at delta opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; Injections, Spinal; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 1994 |
Mu and delta opioid receptors mediate opposite modulations by morphine of the spinal release of cholecystokinin-like material.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Cholecystokinin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Morphine; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord | 1994 |
Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcitonin Gene-Related Peptide; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Iodine Radioisotopes; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Oligopeptides; Pyrrolidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1993 |
Effects of neuropeptide FF analogs on morphine analgesia in the nucleus raphe dorsalis.
Topics: Amino Acid Sequence; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Molecular Sequence Data; Morphine; Neuropeptides; Oligopeptides; Pain Measurement; Pain Threshold; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1995 |
The antinociceptive activity of kappa- but not delta-opioid receptor agonists is maintained in morphine-tolerant neuropathic rats.
Topics: Analgesics, Opioid; Animals; Benzeneacetamides; Drug Tolerance; Male; Morphine; Oligopeptides; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Vocalization, Animal | 1996 |
mu and delta-opioid receptor agonists induce mitogen-activated protein kinase (MAPK) activation in the absence of receptor internalization.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Binding, Competitive; CHO Cells; Concanavalin A; Cricetinae; Dose-Response Relationship, Drug; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Hypertonic Solutions; Mitogen-Activated Protein Kinases; Morphine; Oligopeptides; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu; Sucrose; Time Factors | 2000 |
Anti-analgesic and anti-amnesic effect of complement C3a.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Avoidance Learning; Cerebral Ventricles; Complement C3a; Dose-Response Relationship, Drug; Electroshock; Humans; Injections, Intraventricular; Ischemia; Male; Mice; Mice, Inbred Strains; Morphine; Oligopeptides; Pain; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
Enterostatin (VPDPR) has anti-analgesic and anti-amnesic activities.
Topics: Adjuvants, Anesthesia; Amnesia; Analgesics, Opioid; Animals; Colipases; Enzyme Precursors; Male; Memory; Mice; Mice, Inbred Strains; Morphine; Oligopeptides; Protein Precursors; Scopolamine | 2001 |