delta-philanthotoxin has been researched along with philanthotoxin 343 in 6 studies
| Studies (delta-philanthotoxin) | Trials (delta-philanthotoxin) | Recent Studies (post-2010) (delta-philanthotoxin) | Studies (philanthotoxin 343) | Trials (philanthotoxin 343) | Recent Studies (post-2010) (philanthotoxin 343) |
|---|---|---|---|---|---|
| 63 | 0 | 11 | 39 | 0 | 6 |
| Protein | Taxonomy | delta-philanthotoxin (IC50) | philanthotoxin 343 (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | 0.0802 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 1.465 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.13 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.13 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.13 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 0.0077 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 0.0077 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | 0.0802 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 2.739 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 2.739 | |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | 0.023 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eldefrawi, AT; Eldefrawi, ME; Konno, K; Mansour, NA; Nakanishi, K; Oltz, E; Usherwood, PN | 1 |
| Blagbrough, IS; Brackley, PT; Bruce, M; Bycroft, BW; Mather, AJ; Millington, S; Sudan, HL; Usherwood, PN | 1 |
| Jones, MG; Lodge, D | 1 |
| Andersen, K; Brierley, MJ; Jaroszewski, JW; Krogsgaard-Larsen, P; Mellor, IR; Sløk, FA; Stromgaard, K; Usherwood, PN | 1 |
| Bella, A; Franzyk, H; Frølund, S; Jaroszewski, JW; Kristensen, AS; Olsen, CA; Strømgaard, K; Witt, M; Ziegler, HL | 1 |
| Franzyk, H; Kachel, HS; Mellor, IR; Patel, RN | 1 |
6 other study(ies) available for delta-philanthotoxin and philanthotoxin 343
| Article | Year |
|---|---|
Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.
Topics: Animals; Bee Venoms; Depression, Chemical; Female; Grasshoppers; Muscles; Polyamines; Receptors, AMPA; Receptors, Drug; Synapses; Wasp Venoms; Wasps | 1988 |
Arthropod toxins as leads for novel insecticides: an assessment of polyamine amides as glutamate antagonists.
Topics: Animals; Biological Assay; Glutamates; Grasshoppers; Indoleacetic Acids; Insecticides; Muscles; Oocytes; Phenols; Phenylacetates; Polyamines; Receptors, Glutamate; Receptors, Neurotransmitter; Spider Venoms; Structure-Activity Relationship; Wasp Venoms; Xenopus laevis | 1992 |
Comparison of some arthropod toxins and toxin fragments as antagonists of excitatory amino acid-induced excitation of rat spinal neurones.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Arthropod Venoms; Asparagine; Female; Ibotenic Acid; Indoleacetic Acids; Iontophoresis; Microelectrodes; N-Methylaspartate; Neurons; Neurotoxins; Phenols; Phenylacetates; Polyamines; Rats; Rats, Inbred Strains; Spinal Cord; Wasp Venoms | 1991 |
Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor.
Topics: Animals; Cell Line; Grasshoppers; Magnetic Resonance Spectroscopy; Muscles; Nicotinic Antagonists; Phenols; Polyamines; Receptors, Nicotinic; Spectrometry, Mass, Fast Atom Bombardment | 1999 |
Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Oocytes; Patch-Clamp Techniques; Phenols; Polyamines; Protein Subunits; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Wasp Venoms; Xenopus laevis | 2010 |
Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition.
Topics: Acetylcholine; Animals; Egypt; Female; Humans; Mice; Nicotinic Antagonists; Oocytes; Phenols; Polyamines; Receptors, Nicotinic; Tyrosine; Xenopus laevis | 2016 |