delta-1-pyrroline-5-carboxylate has been researched along with pyrroles in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (37.04) | 18.7374 |
| 1990's | 16 (14.81) | 18.2507 |
| 2000's | 12 (11.11) | 29.6817 |
| 2010's | 31 (28.70) | 24.3611 |
| 2020's | 9 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hayzer, DJ; Krishna, RV; Margraff, R | 1 |
| Herzfeld, A; Knox, WE; Mezl, VA | 1 |
| Boer, P; Sperling, O | 2 |
| Mixson, AJ; Phang, JM | 2 |
| Cami, B; Chippaux, M; Fons, M | 1 |
| Nemoto, N; Sakurai, J | 1 |
| Phang, JM; Semon, BA | 1 |
| Phang, JM | 1 |
| Phang, JM; Yeh, GC | 3 |
| Meister, A; Seddon, AP; Zhao, KY | 1 |
| Fleming, GA; Ford, DB; Granger, A; Phang, JM; Prosser, M; Rogers, QR | 1 |
| Hagedorn, CH; Mick, SJ; Thach, RE | 1 |
| Jones, ME | 1 |
| Leong, SF; McGeer, EG; Thompson, SG; Wong, PT | 1 |
| Jones, ME; Small, C | 1 |
| Seifter, S; Wu, GY | 1 |
| Fleming, GA; Granger, AS; Phang, JM; Steel, G; Valle, D | 1 |
| Abramson, RD; Hagedorn, CH; Merrick, WC; Mick, SJ; Ray, BK; Thach, RE | 1 |
| Hagedorn, CH; Phang, JM | 2 |
| Hagedorn, CH | 1 |
| Kador, PF; Kinoshita, JH; Shiono, T | 1 |
| Fisher, HF; Srinivasan, R | 1 |
| Henslee, JG; Jones, ME; Small, C; Wakabayashi, Y | 1 |
| Smith, RJ | 1 |
| Fleming, GA; Granger, AS; Hagedorn, CH; Phang, JM | 1 |
| Ishiguro, I; Ito, M; Matsuzawa, T | 1 |
| Hagedorn, CH; Phang, JM; Yeh, GC | 2 |
| Downing, SJ; Hagedorn, CH; Phang, JM; Smith, RJ; Williams, JA; Yeh, GC | 1 |
| Ishiguro, I; Matsuzawa, T | 1 |
| Matsuzawa, T | 1 |
| Hopkins, SR; O'Donnell, JJ; Sandman, RP | 1 |
| Bearne, SL; Wolfenden, R | 1 |
| Kim, HR; Kim, JS; Lee, MW; Park, BH; Park, JW; Rho, HW | 1 |
| Jayaswal, RK; Kaenjak, A; Townsend, DE; Wilkinson, BJ | 1 |
| Flynn, NE; Wu, G | 1 |
| Lu, Q; Peng, Z; Verma, DP | 1 |
| de La Fuente, JL; Liras, P; Martín, JF; Rumbero, A | 1 |
| Abdel-Ghaffar, FA; Fahmy, AS; Girgis, RB; Mohamed, SA | 1 |
| Downs, SM; Humpherson, PG; Leese, HJ | 1 |
| Maloy, S; Surber, MW | 1 |
| Downs, SM; Utecht, AM | 1 |
| Miltyk, W; Palka, JA | 1 |
| Farrant, RD; Langley, GJ; Mellor, JM; Mills, GA; Walker, V | 2 |
| Bearne, SL; Hekmat, O; Macdonnell, JE | 1 |
| Deutch, CE; Klarstrom, JL; Link, CL; Ricciardi, DL | 1 |
| VOGEL, HJ; YURA, T | 2 |
| GREENBERG, DM; SMITH, ME | 1 |
| ADAMS, E; GOLDSTONE, A | 3 |
| STRECKER, HJ | 1 |
| PEISACH, J; STRECKER, HJ | 1 |
| Peddibhotla, S; Tepe, JJ | 1 |
| Brosnan, ME; Haslett, MR; Pink, D; Walters, B | 1 |
| Arnett, SO; Gerratana, B; Stapon, A; Townsend, CA | 1 |
| De La Torre-Sanchez, JF; Preis, K; Seidel, GE | 1 |
| Ho, CT; Huang, TC; Huang, YW; Hung, HJ; Wu, ML | 1 |
| Chang, JL; Chuang, HS; Ho, CT; Huang, TC; Teng, CS; Wu, ML | 1 |
| Honig, A; Miller, G; Mittler, R; Stein, H; Suzuki, N; Zilberstein, A | 1 |
| Jakobs, C; Struys, EA | 1 |
| Kotani, T; Nishimura, A; Sasano, Y; Takagi, H | 1 |
| Bazer, FW; Burghardt, RC; Johnson, GA; Kim, SW; Knabe, DA; Li, P; Li, X; McKnight, JR; Satterfield, MC; Spencer, TE; Wu, G | 1 |
| Deutch, CE | 1 |
| Baumer, A; Baumgartner, M; Bozorgmehr, B; Giunta, C; Häberle, J; Hausser, I; Kariminejad, A; Kariminejad, MH; Kretz, R; Rohrbach, M | 1 |
| Csonka, LN; Eilenberg, H; Erster, O; Honig, A; Koncz, C; Miller, G; Stein, H; Szabados, L; Zilberstein, A | 1 |
| Berlicki, L; Forlani, G; Fusetti, M; Joachimiak, A; Kafarski, P; Nocek, B; Petrollino, D; Romanini, L | 1 |
| Kawakami, R; Ohshima, T; Sakuraba, H; Satomura, T | 1 |
| Mysore, KS; Senthil-Kumar, M | 1 |
| Benecke, A; Boulkroun, S; Eilebrecht, S; Golib Dzib, JF; Hütt, MT; Lesne, A; Sonnenschein, N; Zennaro, MC | 1 |
| Akram, NA; Ashraf, M; Jamil, A; Saadia, M | 1 |
| Nasuno, R; Nishimura, A; Takagi, H | 1 |
| Kim, GB; Nam, YW | 1 |
| Jane, WN; Kumar, MN; Verslues, PE | 1 |
| Bremer, E; Flórez, LA; Hoffmann, T; Stülke, J; Wünsche, G; Zaprasis, A | 1 |
| Cvikrová, M; Gemperlová, L; Martincová, O; Vanková, R | 1 |
| Chen, B; Li, Y; Lu, L; Wang, J; Yao, Z; Zhou, H; Zou, C | 1 |
| Alvarez, ME; Cecchini, NM; Hajirezaei, MR; Monteoliva, MI; Rizzi, YS | 1 |
| Dubey, G; Mohan Prasad, S; Pratap Singh, V; Singh, M | 1 |
| Barrett, MP; Bütikofer, P; de Macêdo, JP; Mäser, P; Niemann, M; Roditi, I; Schneider, A; Schumann Burkard, G; Vial, H | 1 |
| AbdElgawad, H; Asard, H; Beemster, GT; De Vos, D; Domagalska, MA; Zinta, G | 1 |
| Sharma, V; Singh, V; Tripathi, BN | 1 |
| Anjum, SA; Ashraf, U; Duan, M; Li, M; Mo, Z; Pan, S; Tang, X; Tian, H | 1 |
| Annunziata, MG; Carillo, P; Ciarmiello, LF; D'Amelia, L; Dell'Aversana, E; Fuggi, A; Iannuzzi, F; Mirto, A; Pacifico, S; Piccolella, S; Woodrow, P | 1 |
| Arentson, BW; Becker, DF; Hayes, EL; Singh, H; Tanner, JJ; Zhu, W | 1 |
| Feng, XJ; Hua, XJ; Jin, JB; Li, JR; Lin, QF; Qi, SL | 1 |
| Aleksza, D; Horváth, GV; Sándor, G; Szabados, L | 1 |
| Dadshani, S; Léon, J; Muzammil, S; Naz, AA; Pillen, K; Shrestha, A; Siddique, S | 1 |
| Chang, L; Chen, G; Guo, Y; Hu, W; Li, G; Shah, K; Tian, H; Wang, L; Yan, Y; Yang, T; Zhang, Y | 1 |
| Blume, C; Laxa, M; Mühlenbruch, M; Ost, J; Peterhänsel, C | 1 |
| Cen, HF; Cui, X; Guan, C; Huang, YH; Tian, DY; Zhang, YW | 1 |
| Anton, DB; Coelho, APD; Dillenburg, LR; Duarte, GL; Guzman, FL; Krause, FA; Kulcheski, FR; Margis, R; Turchetto-Zolet, AC; Vetö, NM | 1 |
| Ashraf, U; Huang, Z; Kong, L; Li, W; Li, Y; Liu, X; Mo, Z; Tang, X; Wang, S; Wu, L; Xie, W | 1 |
| Avila, CC; Damasceno, FS; Elias, MC; Mantilla, BS; Marchese, L; Olavarria, K; Silber, AM; Souza, ROO | 1 |
| Forlani, G; Nocek, B; Ruszkowski, M | 1 |
| Chen, C; Cui, X; Wang, Z; Zhang, J; Zhang, P | 1 |
| Chalecka, M; Kazberuk, A; Palka, J; Surazynski, A | 1 |
| Becker, DF; Patel, SM; Seravalli, J; Stiers, KM; Tanner, JJ | 1 |
| Jiang, W; Shang, L; Wu, W; Zhang, J | 1 |
| Boltje, TJ; Coene, KLM; Engelke, UFH; Hendriks, V; Huigen, MCDG; Körver-Keularts, IMLW; Martens, J; Mecinović, J; Merx, J; Oomens, J; Rutjes, FPJT; van Outersterp, RE; Waterval, HWAH; Wevers, RA | 1 |
5 review(s) available for delta-1-pyrroline-5-carboxylate and pyrroles
| Article | Year |
|---|---|
The regulatory functions of proline and pyrroline-5-carboxylic acid.
Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship | 1985 |
Intestinal ornithine synthesis from glutamic acid.
Topics: Alanine Transaminase; Animals; Arginine; Cats; Glutamates; Glutamic Acid; Intestinal Mucosa; Intestine, Small; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyrroles; Rats | 1985 |
Proline and hydroxyproline metabolism: implications for animal and human nutrition.
Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Birds; Chickens; Collagen; Diet; Dietary Supplements; Fishes; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Infant; Infant, Newborn; Milk; Nutritional Requirements; Proline; Pyrroles; Swine | 2011 |
L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application.
Topics: Amino Acid Sequence; Archaea; Coenzymes; Models, Molecular; Molecular Sequence Data; Proline; Proline Oxidase; Protein Multimerization; Protein Subunits; Pyrroles | 2012 |
P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis.
Topics: Amino Acids; Animals; Apoptosis; Cell Survival; Humans; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles | 2021 |
103 other study(ies) available for delta-1-pyrroline-5-carboxylate and pyrroles
| Article | Year |
|---|---|
Enzymic synthesis of glutamic acid gamma-semialdehyde (delta 1-pyrroline-5-carboxylate) and N-acetyl-L-glutamic acid gamma-semialdehyde: isolation and characterization of their 2,4-dinitrophenylhydrazones.
Topics: Aldehydes; Animals; Chemical Phenomena; Chemistry; Chromatography; Dinitrobenzenes; Glutamates; Hydrazones; Ornithine-Oxo-Acid Transaminase; Pseudomonas aeruginosa; Pyrroles; Rats; Transaminases | 1979 |
Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues.
Topics: Animals; Fetus; Neoplasms, Experimental; Oxidoreductases; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Stereoisomerism; Temperature | 1977 |
Stimulation of ribose-5-phosphate and 5-phosphoribosyl-1-pyrophosphate generation by pyrroline-5-carboxylate in mouse liver in vivo: evidence for a regulatory role of ribose-5-phosphate availability in nucleotide synthesis.
Topics: Animals; Liver; Male; Mice; Mice, Inbred ICR; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrroles; Ribosemonophosphates | 1991 |
The effect of pyrroline-5-carboxylate on R5P and PRPP generation in mouse liver in vivo.
Topics: Animals; Kinetics; Liver; Male; Mice; Mice, Inbred ICR; Phosphoribosyl Pyrophosphate; Pyrroles; Ribosemonophosphates | 1991 |
Structural analogues of pyrroline 5-carboxylate specifically inhibit its uptake into cells.
Topics: Animals; Biological Transport, Active; Borohydrides; Carrier Proteins; Cell Line; Kinetics; Pyrroles; Structure-Activity Relationship; Sulfhydryl Reagents | 1991 |
Possible involvement of a L-delta 1-pyrroline-5-carboxylate (P5C) reductase in the synthesis of proline in Desulfovibrio desulfuricans Norway.
Topics: Desulfovibrio; DNA, Bacterial; Enzyme Stability; Escherichia coli; Gene Expression; Genotype; Hot Temperature; Plasmids; Proline; Pyrroles | 1991 |
Proline is required for transcriptional control of the aromatic hydrocarbon-inducible P(1)450 gene in C57BL/6 mouse monolayer-cultured hepatocytes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Mice; Mice, Inbred C57BL; Ornithine; Polycyclic Compounds; Proline; Pyrroles; RNA, Messenger; Transcription, Genetic | 1991 |
Accumulation of pyrroline 5-carboxylic acid in conditioned medium of cultured fibroblast: stimulatory effects of serum, insulin, and IGF-1.
Topics: Blood; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Humans; Insulin; Insulin-Like Growth Factor I; Kinetics; Pyrroles; Skin | 1991 |
Stimulation of phosphoribosyl pyrophosphate and purine nucleotide production by pyrroline 5-carboxylate in human erythrocytes.
Topics: Adenine Nucleotides; Adult; Blood Glucose; Erythrocytes; Humans; Inosine Monophosphate; Oxidation-Reduction; Pentose Phosphate Pathway; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrroles; Ribonucleotides | 1988 |
Activation of glutamate by gamma-glutamate kinase: formation of gamma-cis-cycloglutamyl phosphate, an analog of gamma-glutamyl phosphate.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aldehyde Oxidoreductases; Chromatography, High Pressure Liquid; Drug Stability; Escherichia coli; Glutamate-5-Semialdehyde Dehydrogenase; Glutamates; Glutamic Acid; Hydroxamic Acids; Kinetics; Molecular Conformation; NADP; Organophosphorus Compounds; Phosphates; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Pyrroles; Pyrrolidonecarboxylic Acid | 1989 |
Fluctuations in plasma pyrroline-5-carboxylate concentrations during feeding and fasting.
Topics: Adult; Eating; Energy Intake; Fasting; Female; Humans; Male; Pyrroles; Time Factors | 1989 |
Selective inhibition of proteins synthesized from different mRNA species in reticulocyte lysates containing L-pyrroline-5-carboxylic acid.
Topics: Animals; Encephalomyocarditis virus; Globins; Glutathione; Medicago sativa; Mosaic Viruses; NAD; NADP; Protein Biosynthesis; Pyrroles; Rabbits; Rats; Reticulocytes; RNA, Messenger; RNA, Viral | 1988 |
Conversion of glutamate to ornithine and proline: pyrroline-5-carboxylate, a possible modulator of arginine requirements.
Topics: Amino Acids; Animals; Arginine; Biotransformation; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Kidney; Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Retinal Degeneration; Spleen | 1985 |
Regional distribution in rat brain of 1-pyrroline-5-carboxylate dehydrogenase and its localization to specific glial cells.
Topics: Animals; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Neuroglia; Ornithine; Proline Oxidase; Pyrroles; Rats; Rats, Inbred Strains | 1985 |
A specific radiochemical assay for pyrroline-5-carboxylate dehydrogenase.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Carbon Radioisotopes; Glutamates; Glutamic Acid; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Pyrroles; Spectrophotometry; Tritium | 1987 |
Periodate oxidation products of hydroxylysine in the synthesis of 5-substituted prolines.
Topics: Hydrogen-Ion Concentration; Hydroxylysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Proline; Pyrroles; Spectrophotometry, Infrared; Temperature | 1985 |
The aqueous humor of rabbit contains high concentrations of pyrroline-5-carboxylate.
Topics: Animals; Aqueous Humor; Guinea Pigs; Haplorhini; Male; Models, Chemical; Pigmentation; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits; Species Specificity; Tissue Distribution | 1986 |
The uptake of pyrroline 5-carboxylate. Group translocation mediating the transfer of reducing-oxidizing potential.
Topics: Amino Acids; Animals; Biological Transport; Cell Line; Kinetics; Oxidation-Reduction; Pentose Phosphate Pathway; Pyrroles | 1988 |
Induction of eIF-4E phosphorylation by the addition of L-pyrroline-5-carboxylic acid to rabbit reticulocyte lysate.
Topics: Animals; Eukaryotic Initiation Factor-4E; In Vitro Techniques; Isoelectric Point; Molecular Weight; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Protein Synthesis Inhibitors; Pyrroles; Rabbits; Reticulocytes; RNA Caps | 1988 |
Catalytic transfer of hydride ions from NADPH to oxygen by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
Topics: Adenosine Triphosphate; Animals; Humans; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxygen; Proline; Pyrroles; Rats | 1986 |
Demonstration of a NADPH-linked delta 1-pyrroline-5-carboxylate-proline shuttle in a cell-free rat liver system.
Topics: Animals; Cell-Free System; Cold Temperature; Mitochondria, Liver; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Solubility | 1986 |
Stimulation of the hexose monophosphate pathway by pyrroline-5-carboxylate reductase in the lens.
Topics: Aging; Animals; Female; Glucose; Glutamine; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains | 1985 |
Reversible reduction of an alpha-imino acid to an alpha-amino acid catalyzed by glutamate dehydrogenase: effect of ionizable functional groups.
Topics: Animals; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Mathematics; NADP; Oxidation-Reduction; Proline; Pyrroles | 1985 |
Factors influencing pyrroline 5-carboxylate synthesis from glutamate by rat intestinal mucosa mitochondria.
Topics: Animals; Carbon Radioisotopes; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Mitochondria; Ornithine; Pyridoxal Phosphate; Pyrroles; Rats; Rats, Inbred Strains | 1983 |
A radioisotopic assay for delta 1-pyrroline-5-carboxylate synthase activity.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cricetinae; Glutamates; Glutamic Acid; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Transaminases | 1984 |
The stimulation of purine nucleotide production by pyrroline-5-carboxylic acid in human erythrocytes.
Topics: Erythrocytes; Female; Humans; Kinetics; Male; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Pyrroles | 1981 |
Pyrroline-5-carboxylate stimulates the conversion of purine antimetabolites to their nucleotide forms by a redox-dependent mechanism.
Topics: Azathioprine; Erythrocytes; Humans; Inosine Monophosphate; Inosine Nucleotides; Mercaptopurine; Oxidation-Reduction; Phosphates; Phosphoribosyl Pyrophosphate; Pyrroles; Thioguanine; Thionucleotides | 1983 |
Transfer of reducing equivalents into mitochondria by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
Topics: Animals; Catalysis; Cell-Free System; Cytosol; Glucose; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Male; Mitochondria, Liver; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains | 1983 |
Pyrroline-5-carboxylate in human plasma.
Topics: Chromatography, Ion Exchange; Female; Humans; Male; Methods; Proline; Pyrroles; Saliva | 1984 |
Enzymatic assays of L-ornithine and L-delta 1-pyrroline-5-carboxylate in tissues, and orniathine-load test in human subjects.
Topics: Adolescent; Adult; Animals; Diabetes Mellitus; Female; Fluorometry; Humans; Liver Cirrhosis; Male; Middle Aged; Ornithine; Ornithine-Oxo-Acid Transaminase; Oxidoreductases Acting on CH-NH Group Donors; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Transaminases | 1980 |
The intercellular proline cycle.
Topics: Animals; Erythrocytes; Humans; Liver; Mice; Mitochondria, Liver; NADP; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases | 1981 |
Stimulation of the hexosemonophosphate-pentose pathway by pyrroline-5-carboxylate in cultured cells.
Topics: Animals; Cell Line; Cells, Cultured; Citric Acid Cycle; Cricetinae; Female; Fibroblasts; Glucose; Hexosephosphates; Humans; Kidney; NADP; Ovary; Oxidation-Reduction; Pentoses; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits | 1982 |
delta 1-Pyrroline-5-carboxylate reductase from Baker's yeast. Purification, properties and its application in the assays of L-delta 1-pyrroline-5-carboxylate and L-ornithine in tissue.
Topics: Animals; Liver; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Saccharomyces cerevisiae | 1980 |
Transfer of 1-pyrroline-5-carboxylate as oxidizing potential from hepatocytes to erythrocytes.
Topics: Animals; Erythrocytes; Humans; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Pentosephosphates; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1982 |
Disease of the ornithine-proline pathway: delta 1-pyrroline-5-carboxylate reductase deficiency in the retina of retinal degeneration mice.
Topics: Animals; Cattle; Eye; Liver; Mice; Mice, Inbred Strains; Ornithine; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Retinal Degeneration; Weaning | 1982 |
The hexose monophosphate pentose pathway in fibroblasts deficient in L-ornithine: 2-oxoacid aminotransferase activity.
Topics: Adolescent; Cells, Cultured; Female; Glucose; Hexosephosphates; Humans; Ornithine-Oxo-Acid Transaminase; Pentosephosphates; Pyrroles; Retinal Degeneration; Transaminases | 1980 |
Glutamate gamma-semialdehyde as a natural transition state analogue inhibitor of Escherichia coli glucosamine-6-phosphate synthase.
Topics: Enzyme Inhibitors; Escherichia coli; Glutamates; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Kinetics; Magnetic Resonance Spectroscopy; Pyrroles; Substrate Specificity | 1995 |
Assay of ornithine aminotransferase with ninhydrin.
Topics: Animals; Benzaldehydes; Colorimetry; Drug Stability; Intestine, Small; Liver; Male; Mice; Mice, Inbred ICR; Ninhydrin; Ornithine-Oxo-Acid Transaminase; Pyrroles; Sensitivity and Specificity; Spectrophotometry; Tissue Distribution | 1994 |
Proline is biosynthesized from arginine in Staphylococcus aureus.
Topics: Arginine; Bacterial Proteins; Carbon; DNA Transposable Elements; Glutamic Acid; Ornithine; Proline; Pyrroles; Staphylococcus aureus | 1996 |
An important role for endogenous synthesis of arginine in maintaining arginine homeostasis in neonatal pigs.
Topics: Administration, Oral; Amino Acids; Animals; Animals, Newborn; Arginine; Citrulline; Cyclohexanecarboxylic Acids; Glutamine; Homeostasis; Intestinal Mucosa; Intestines; Muscle, Skeletal; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyrroles; Swine | 1996 |
Reciprocal regulation of delta 1-pyrroline-5-carboxylate synthetase and proline dehydrogenase genes controls proline levels during and after osmotic stress in plants.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Sequence; Animals; Arabidopsis; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Molecular Sequence Data; Osmotic Pressure; Oxidoreductases Acting on CH-NH Group Donors; Proline; Proline Oxidase; Pyrroles; RNA, Messenger; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Transcription, Genetic; Water | 1996 |
Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms alpha-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes.
Topics: 2-Aminoadipic Acid; Bacterial Proteins; Cephamycins; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Kinetics; L-Lysine 6-Transaminase; Lysine; Molecular Weight; NAD; Oxidoreductases Acting on CH-NH Group Donors; Picolinic Acids; Pipecolic Acids; Piperidines; Pyrroles; Quaternary Ammonium Compounds; Streptomyces; Substrate Specificity; Transaminases | 1997 |
Enzymes of delta 1-pyrroline-5-carboxylate metabolism in the camel tick Hyalomma dromedarii during embryogenesis. Purification and characterization of delta 1-pyrroline-5-carboxylate dehydrogenases.
Topics: Adenine Nucleotides; Aldehydes; Amino Acids; Animals; Cations, Divalent; delta-1-Pyrroline-5-Carboxylate Reductase; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; Isoenzymes; Molecular Weight; Ovum; Pyrroles; Pyrroline Carboxylate Reductases; Substrate Specificity; Ticks | 1997 |
Meiotic induction in cumulus cell-enclosed mouse oocytes: involvement of the pentose phosphate pathway.
Topics: Animals; Deoxyglucose; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Meiosis; Methylene Blue; Mice; Mice, Inbred C57BL; NADP; NADPH Oxidases; Oocytes; Ovarian Follicle; Oxidation-Reduction; Pentose Phosphate Pathway; Phenazines; Phosphogluconate Dehydrogenase; Pyrroles | 1998 |
The PutA protein of Salmonella typhimurium catalyzes the two steps of proline degradation via a leaky channel.
Topics: Bacterial Proteins; Binding, Competitive; Catalysis; Kinetics; Membrane Proteins; NAD; Proline; Proline Oxidase; Pyrroles; Salmonella typhimurium; Substrate Specificity | 1998 |
Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Chorionic Gonadotropin; Female; Follicle Stimulating Hormone; Glucose; Glycolysis; Hypoxanthine; Kinetics; Meiosis; Mice; Mice, Inbred C57BL; Oocytes; Ovarian Follicle; Oxidation-Reduction; Pentose Phosphate Pathway; Pyrroles; Tritium | 1999 |
Potential role of pyrroline 5-carboxylate in regulation of collagen biosynthesis in cultured human skin fibroblasts.
Topics: Animals; Cells, Cultured; Collagen; Culture Media, Serum-Free; Fasting; Fibroblasts; Humans; Insulin-Like Growth Factor I; Male; Pyrroles; Rats; Rats, Wistar; Skin | 2000 |
Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II.
Topics: Aldehydes; Avitaminosis; Chromatography, High Pressure Liquid; Humans; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Proline; Pyridoxal Phosphate; Pyridoxine; Pyrroles; Seizures | 2001 |
Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.
Topics: Allosteric Regulation; Aminobutyrates; Carbon-Nitrogen Ligases; Cysteine; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Glutamates; Glutamine; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Pyrroles; Pyrrolidonecarboxylic Acid; Quaternary Ammonium Compounds; Recombinant Proteins | 2001 |
Oxidation of L-thiazolidine-4-carboxylate by delta1-pyrroline-5-carboxylate reductase in Escherichia coli.
Topics: Animals; Antioxidants; delta-1-Pyrroline-5-Carboxylate Reductase; Escherichia coli; Mice; Mutation; Oxidation-Reduction; Pyrroles; Pyrroline Carboxylate Reductases; Substrate Specificity; Thiazoles; Thiazolidines | 2001 |
A novel pyrroline-5-carboxylic acid and acetoacetic acid adduct in hyperprolinaemia type II.
Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Child; Female; Gas Chromatography-Mass Spectrometry; Humans; Proline; Pyridoxal Phosphate; Pyrroles; Stereoisomerism | 2003 |
On the biosynthesis of proline in Neurospora crassa: enzymic reduction of delta1-pyrroline-5-carboxylate.
Topics: Neurospora; Neurospora crassa; Proline; Pyrroles | 1955 |
Characterization of an enzyme reducing pyrroline-5-carboxylate to proline.
Topics: Humans; Liver; Oxidoreductases; Proline; Pyrroles | 1956 |
Pyrroline-5-carboxylate reductase of Neurospora crassa; partial purification and some properties.
Topics: Neurospora; Neurospora crassa; Oxidoreductases; Pyrroles | 1959 |
Hydroxyproline metabolism. II. Enzymatic preparation and properties of Delta 1-pyrroline-3-hydroxy-5-carboxylic acid.
Topics: Carboxylic Acids; Hydroxyproline; Proline; Pyrroles | 1960 |
Hydroxyproline metabolism. III. Enzymatic synthesis of hydroxyproline from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
Topics: Hydroxyproline; Proline; Pyrroles | 1960 |
Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
Topics: Amino Acids; Glutamates; Hydroxyproline; Proline; Pyrroles | 1960 |
The interconversion of glutamic acid and proline. II. The preparation and properties of delta 1-pyrroline-5-carboxylic acid.
Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles | 1960 |
The interconversion of glutamic acid and proline. V. The reduction of delta 1-pyrroline-5-carboxylic acid to proline.
Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles | 1962 |
Stereoselective synthesis of highly substituted Delta1-pyrrolines: exo-selective 1,3-dipolar cycloaddition reactions with azlactones.
Topics: Alkenes; Aza Compounds; Catalysis; Cyclization; Lactones; Pyrroles; Silver; Stereoisomerism | 2004 |
Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.
Topics: Animals; Glutamic Acid; Liver; Male; Mitochondria; NADP; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions; Ultracentrifugation | 2004 |
Carboxymethylproline synthase from Pectobacterium carotorova: a multifaceted member of the crotonase superfamily.
Topics: Acyl Coenzyme A; Carbon-Carbon Lyases; Catalysis; Decarboxylation; Enoyl-CoA Hydratase; Hydrolysis; Kinetics; Pyrroles; Substrate Specificity | 2004 |
Metabolic regulation of in-vitro-produced bovine embryos. I. Effects of metabolic regulators at different glucose concentrations with embryos produced by semen from different bulls.
Topics: 2,4-Dinitrophenol; Animals; Blastocyst; Cattle; Culture Media; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; Glucose; Male; Morula; Phenazines; Phloretin; Pyrroles; Semen; Sodium Azide | 2006 |
Delta1-pyrroline-5-carboxylic acid formed by proline dehydrogenase from the Bacillus subtilis ssp. natto expressed in Escherichia coli as a precursor for 2-acetyl-1-pyrroline.
Topics: Amino Acid Sequence; Bacillus subtilis; Escherichia coli; Gene Expression; Molecular Sequence Data; Proline Oxidase; Pyrroles; Recombinant Proteins; Sequence Alignment | 2007 |
Biosynthetic mechanism of 2-acetyl-1-pyrroline and its relationship with Delta1-pyrroline-5-carboxylic acid and methylglyoxal in aromatic rice (Oryza sativa L.) callus.
Topics: Odorants; Oryza; Pyrroles; Pyruvaldehyde; Seeds | 2008 |
Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Arabidopsis; Arabidopsis Proteins; Droughts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamic Acid; Hot Temperature; Medicago sativa; Mitochondria; Mutation; Nicotiana; Oxidation-Reduction; Plants; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride | 2009 |
Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: evidence for an alternative pathway of pipecolic acid formation.
Topics: Aldehyde Dehydrogenase; Cell Line; Fibroblasts; Humans; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Neoplasm Proteins; Picolinic Acids; Pipecolic Acids; Pyrroles | 2010 |
An antioxidative mechanism mediated by the yeast N-acetyltransferase Mpr1: oxidative stress-induced arginine synthesis and its physiological role.
Topics: Acetylation; Acetyltransferases; Arginine; Gene Knockout Techniques; Glutamates; Metabolic Networks and Pathways; Microbial Viability; Models, Biological; Mutagenesis, Insertional; Oxidative Stress; Proline Oxidase; Pyrroles; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stress, Physiological; Temperature | 2010 |
L-Proline nutrition and catabolism in Staphylococcus saprophyticus.
Topics: Arginine; Cell Membrane; Culture Media; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases; Staphylococcus saprophyticus | 2011 |
Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities.
Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Collagen; delta-1-Pyrroline-5-Carboxylate Reductase; DNA Mutational Analysis; Elastin; Family; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Middle Aged; Models, Biological; Mutation, Missense; Phenotype; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Young Adult | 2011 |
Elevation of free proline and proline-rich protein levels by simultaneous manipulations of proline biosynthesis and degradation in plants.
Topics: Arabidopsis; Bacterial Proteins; Cell Wall; Chloroplasts; Cytosol; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Medicago sativa; Mutation; Nicotiana; Phosphotransferases (Carboxyl Group Acceptor); Plant Proteins; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; RNA, Antisense; RNA, Plant; Salinity; Stress, Physiological | 2011 |
Δ1-pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo.
Topics: Amino Acids; Anti-Bacterial Agents; Bacterial Proteins; Cloning, Molecular; Diphosphonates; Enzyme Inhibitors; Escherichia coli; Humans; Inhibitory Concentration 50; Kinetics; Microbial Viability; Molecular Structure; Pyrroles; Pyrroline Carboxylate Reductases; Recombinant Proteins; Streptococcus pyogenes | 2012 |
Ornithine-delta-aminotransferase and proline dehydrogenase genes play a role in non-host disease resistance by regulating pyrroline-5-carboxylate metabolism-induced hypersensitive response.
Topics: Arabidopsis; Disease Resistance; Gene Expression Regulation, Plant; Gene Silencing; Mitochondria; Nicotiana; Ornithine-Oxo-Acid Transaminase; Plant Proteins; Proline; Proline Oxidase; Pseudomonas syringae; Pyrroles; Reactive Oxygen Species | 2012 |
A network perspective on metabolic inconsistency.
Topics: Adenoma; Adipates; Adrenal Glands; Aldosterone; Humans; Metabolic Networks and Pathways; Proline; Pyrroles; Systems Biology; Transcriptome | 2012 |
A study of proline metabolism in canola (Brassica napus L.) seedlings under salt stress.
Topics: Brassica napus; Gene Expression Regulation, Plant; Phosphotransferases (Alcohol Group Acceptor); Plant Roots; Plant Shoots; Proline; Proline Oxidase; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Salt Tolerance; Seedlings; Sodium Chloride | 2012 |
The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast.
Topics: Anions; Cell Death; Dose-Response Relationship, Drug; Gene Expression Regulation, Fungal; Mitochondria; Models, Biological; Oxidative Stress; Oxygen Consumption; Proline; Pyrroles; Reactive Oxygen Species; Saccharomyces cerevisiae; Superoxides; Time Factors | 2012 |
A novel Δ(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation.
Topics: Gene Expression Regulation, Plant; Medicago truncatula; Nitrogen; Nitrogen Fixation; Ornithine-Oxo-Acid Transaminase; Plant Growth Regulators; Proline; Pyrroles; Stress, Physiological; Symbiosis | 2013 |
Role of the putative osmosensor Arabidopsis histidine kinase1 in dehydration avoidance and low-water-potential response.
Topics: Abscisic Acid; Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Blotting, Western; Dehydration; Dioxygenases; Gene Expression Regulation, Plant; Ligases; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; Mutation; Osmolar Concentration; Plant Stomata; Plant Transpiration; Proline; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Water; Water-Electrolyte Balance | 2013 |
Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.
Topics: Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Base Sequence; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutation; Proline; Promoter Regions, Genetic; Pyrroles; Sequence Alignment; Trans-Activators | 2014 |
Effect of drought and combined drought and heat stress on polyamine metabolism in proline-over-producing tobacco plants.
Topics: Adaptation, Physiological; Arabidopsis Proteins; Droughts; Genes, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Malondialdehyde; Multienzyme Complexes; Nicotiana; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Phosphotransferases (Alcohol Group Acceptor); Plant Leaves; Plant Proteins; Plant Roots; Polyamine Oxidase; Polyamines; Proline; Putrescine; Pyrroles; Spermidine; Spermine; Transformation, Genetic; Water | 2013 |
Δ(1)-pyrroline-5-carboxylate/glutamate biogenesis is required for fungal virulence and sporulation.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Ascomycota; Eleocharis; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Glutamic Acid; Phylogeny; Proline Oxidase; Pyrroles; Recombinant Proteins; Saccharomyces cerevisiae; Spores, Fungal; Virulence | 2013 |
Context of action of proline dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species | 2014 |
Exogenous proline application ameliorates toxic effects of arsenate in Solanum melongena L. seedlings.
Topics: Antioxidants; Arsenates; Catalase; Chlorophyll; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Photosynthesis; Photosystem II Protein Complex; Proline; Pyrroles; Reactive Oxygen Species; Seedlings; Solanum melongena; Superoxide Dismutase | 2015 |
An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.
Topics: Biological Transport; Cell Proliferation; Drug Resistance, Multiple; Energy Metabolism; Gene Expression Regulation; Gene Knockout Techniques; Membrane Potential, Mitochondrial; Metabolomics; Mitochondria; Mitochondrial Membrane Transport Proteins; Parasitic Sensitivity Tests; Pentamidine; Proline; Protein Structure, Tertiary; Protozoan Proteins; Pyrroles; Recombinant Proteins; RNA Interference; Trypanocidal Agents; Trypanosoma brucei brucei | 2015 |
Grassland species differentially regulate proline concentrations under future climate conditions: an integrated biochemical and modelling approach.
Topics: Climate; Glutamic Acid; Grassland; Metabolic Networks and Pathways; Models, Biological; Monte Carlo Method; Ornithine; Proline; Pyrroles; RNA, Messenger; Species Specificity; Thermodynamics | 2015 |
Interaction of Mg with heavy metals (Cu, Cd) in T. aestivum with special reference to oxidative and proline metabolism.
Topics: Ascorbate Peroxidases; Carotenoids; Catalase; Chlorophyll; Chlorophyll A; Hydrogen Peroxide; Magnesium; Malondialdehyde; Metals, Heavy; Oxidation-Reduction; Plant Roots; Plant Shoots; Proline; Pyrroles; Superoxide Dismutase; Triticum | 2016 |
Manganese-induced regulations in growth, yield formation, quality characters, rice aroma and enzyme involved in 2-acetyl-1-pyrroline biosynthesis in fragrant rice.
Topics: Gene Expression Regulation, Plant; Manganese; Ornithine-Oxo-Acid Transaminase; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles; Seeds | 2016 |
Durum wheat seedling responses to simultaneous high light and salinity involve a fine reconfiguration of amino acids and carbohydrate metabolism.
Topics: Amino Acids; Carbohydrate Metabolism; Carbon; gamma-Aminobutyric Acid; Light; Models, Biological; Nitrogen; Photosynthesis; Pyrroles; Salinity; Seedlings; Sodium Chloride; Stress, Physiological; Triticum; Water | 2017 |
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA.
Topics: Bacterial Proteins; Chimera; DNA-Binding Proteins; Escherichia coli; Membrane Proteins; Proline; Proline Oxidase; Protein Binding; Protein Domains; Pyrroles; Rhodobacter capsulatus | 2016 |
Light affects salt stress-induced transcriptional memory of P5CS1 in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Basic-Leucine Zipper Transcription Factors; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Histones; Light; Multienzyme Complexes; Mutation; Nuclear Proteins; Phosphotransferases (Alcohol Group Acceptor); Plants, Genetically Modified; Pyrroles; Salts; Seeds; Signal Transduction; Stress, Physiological; Transcription, Genetic; Two-Hybrid System Techniques | 2016 |
Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation.
Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Binding Sites; Glutamate-5-Semialdehyde Dehydrogenase; Multienzyme Complexes; Mutation; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Plant Growth Regulators; Proline; Promoter Regions, Genetic; Pyrroles; Signal Transduction; Transcription Factors; Transcriptional Activation | 2017 |
An Ancestral Allele of
Topics: Adaptation, Physiological; Alleles; Arabidopsis; Chromosome Mapping; Chromosomes, Plant; Droughts; Hordeum; Plant Roots; Proline; Pyrroles; Quantitative Trait Loci; Water | 2018 |
1-Pyrroline-5-carboxylate released by prostate Cancer cell inhibit T cell proliferation and function by targeting SHP1/cytochrome c oxidoreductase/ROS Axis.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Cytochromes c; Cytokines; Disease Models, Animal; Electron Transport Chain Complex Proteins; Heterografts; Humans; Lymphocyte Activation; Male; Metabolome; Metabolomics; Mice; Mitochondria; Prostatic Neoplasms; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyrroles; Reactive Oxygen Species; T-Lymphocytes; Tandem Mass Spectrometry | 2018 |
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea | 2019 |
Overexpression of the Lolium perenne L. delta1-pyrroline 5-carboxylate synthase (LpP5CS) gene results in morphological alterations and salinity tolerance in switchgrass (Panicum virgatum L.).
Topics: Agrobacterium; Biomass; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Lolium; Panicum; Plant Proteins; Plants, Genetically Modified; Pyrroles; Reactive Oxygen Species; Salt Tolerance; Salts; Sequence Analysis, RNA | 2019 |
Characterization and expression analysis of P5CS (Δ1-pyrroline-5-carboxylate synthase) gene in two distinct populations of the Atlantic Forest native species Eugenia uniflora L.
Topics: Aldehyde Dehydrogenase; Droughts; Eugenia; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Ligases; Multienzyme Complexes; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Plants; Proline; Pyrroles; Stress, Physiological | 2020 |
Selenium-silicon (Se-Si) induced modulations in physio-biochemical responses, grain yield, quality, aroma formation and lodging in fragrant rice.
Topics: Antioxidants; Dose-Response Relationship, Drug; Edible Grain; Malondialdehyde; Odorants; Oryza; Proline; Pyrroles; Selenium; Silicon; Soil | 2020 |
Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools.
Topics: Cytosol; Electron Transport; Glutamic Acid; Mitochondria; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Trypanosoma cruzi | 2020 |
Peculiar substrate specificity of δ
Topics: Catalysis; Electrons; Kinetics; NAD; NADP; Oxidoreductases; Pyrroles; Substrate Specificity; Zymomonas | 2021 |
Expression of the pyrroline-5-carboxylate reductase (P5CR) gene from the wild grapevine Vitis yeshanensis promotes drought resistance in transgenic Arabidopsis.
Topics: Arabidopsis; delta-1-Pyrroline-5-Carboxylate Reductase; Droughts; Gene Expression Regulation, Plant; Hydrogen Peroxide; Oxidoreductases; Plant Proteins; Plants, Genetically Modified; Pyrroles; Pyrroline Carboxylate Reductases; Stress, Physiological; Vitis | 2021 |
Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
Topics: Binding Sites; Cysteine; Humans; Kinetics; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Thiazolidines | 2021 |
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells.
Topics: Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Liver Neoplasms; Naphthoquinones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Pyrroline Carboxylate Reductases; TOR Serine-Threonine Kinases | 2022 |
Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Biomarkers; Phosphates; Proline; Proline Oxidase; Pyridoxal; Pyrroles | 2022 |