delta-1-pyrroline-5-carboxylate and proline

delta-1-pyrroline-5-carboxylate has been researched along with proline in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199023 (35.38)18.7374
1990's5 (7.69)18.2507
2000's4 (6.15)29.6817
2010's23 (35.38)24.3611
2020's10 (15.38)2.80

Authors

AuthorsStudies
Herzfeld, A; Knox, WE; Mezl, VA1
Cami, B; Chippaux, M; Fons, M1
Nemoto, N; Sakurai, J1
Phang, JM1
Jones, ME1
Seifter, S; Wu, GY1
Fleming, GA; Granger, AS; Phang, JM; Steel, G; Valle, D1
Hagedorn, CH; Phang, JM2
Hagedorn, CH1
Kador, PF; Kinoshita, JH; Shiono, T1
Fisher, HF; Srinivasan, R1
Smith, RJ1
Fleming, GA; Granger, AS; Hagedorn, CH; Phang, JM1
Hagedorn, CH; Phang, JM; Yeh, GC2
Downing, SJ; Hagedorn, CH; Phang, JM; Smith, RJ; Williams, JA; Yeh, GC1
Matsuzawa, T1
Jayaswal, RK; Kaenjak, A; Townsend, DE; Wilkinson, BJ1
Lu, Q; Peng, Z; Verma, DP1
Maloy, S; Surber, MW1
Farrant, RD; Langley, GJ; Mellor, JM; Mills, GA; Walker, V2
VOGEL, HJ; YURA, T1
GREENBERG, DM; SMITH, ME1
ADAMS, E; GOLDSTONE, A3
STRECKER, HJ1
PEISACH, J; STRECKER, HJ1
Brosnan, ME; Haslett, MR; Pink, D; Walters, B1
Honig, A; Miller, G; Mittler, R; Stein, H; Suzuki, N; Zilberstein, A1
Bazer, FW; Burghardt, RC; Johnson, GA; Kim, SW; Knabe, DA; Li, P; Li, X; McKnight, JR; Satterfield, MC; Spencer, TE; Wu, G1
Deutch, CE1
Baumer, A; Baumgartner, M; Bozorgmehr, B; Giunta, C; Häberle, J; Hausser, I; Kariminejad, A; Kariminejad, MH; Kretz, R; Rohrbach, M1
Csonka, LN; Eilenberg, H; Erster, O; Honig, A; Koncz, C; Miller, G; Stein, H; Szabados, L; Zilberstein, A1
Kawakami, R; Ohshima, T; Sakuraba, H; Satomura, T1
Mysore, KS; Senthil-Kumar, M1
Benecke, A; Boulkroun, S; Eilebrecht, S; Golib Dzib, JF; Hütt, MT; Lesne, A; Sonnenschein, N; Zennaro, MC1
Akram, NA; Ashraf, M; Jamil, A; Saadia, M1
Nasuno, R; Nishimura, A; Takagi, H1
Kim, GB; Nam, YW1
Jane, WN; Kumar, MN; Verslues, PE1
Bremer, E; Flórez, LA; Hoffmann, T; Stülke, J; Wünsche, G; Zaprasis, A1
Cvikrová, M; Gemperlová, L; Martincová, O; Vanková, R1
Alvarez, ME; Cecchini, NM; Hajirezaei, MR; Monteoliva, MI; Rizzi, YS1
Dubey, G; Mohan Prasad, S; Pratap Singh, V; Singh, M1
Barrett, MP; Bütikofer, P; de Macêdo, JP; Mäser, P; Niemann, M; Roditi, I; Schneider, A; Schumann Burkard, G; Vial, H1
AbdElgawad, H; Asard, H; Beemster, GT; De Vos, D; Domagalska, MA; Zinta, G1
Sharma, V; Singh, V; Tripathi, BN1
Anjum, SA; Ashraf, U; Duan, M; Li, M; Mo, Z; Pan, S; Tang, X; Tian, H1
Arentson, BW; Becker, DF; Hayes, EL; Singh, H; Tanner, JJ; Zhu, W1
Aleksza, D; Horváth, GV; Sándor, G; Szabados, L1
Dadshani, S; Léon, J; Muzammil, S; Naz, AA; Pillen, K; Shrestha, A; Siddique, S1
Blume, C; Laxa, M; Mühlenbruch, M; Ost, J; Peterhänsel, C1
Anton, DB; Coelho, APD; Dillenburg, LR; Duarte, GL; Guzman, FL; Krause, FA; Kulcheski, FR; Margis, R; Turchetto-Zolet, AC; Vetö, NM1
Ashraf, U; Huang, Z; Kong, L; Li, W; Li, Y; Liu, X; Mo, Z; Tang, X; Wang, S; Wu, L; Xie, W1
Avila, CC; Damasceno, FS; Elias, MC; Mantilla, BS; Marchese, L; Olavarria, K; Silber, AM; Souza, ROO1
Chalecka, M; Kazberuk, A; Palka, J; Surazynski, A1
Becker, DF; Patel, SM; Seravalli, J; Stiers, KM; Tanner, JJ1
Boltje, TJ; Coene, KLM; Engelke, UFH; Hendriks, V; Huigen, MCDG; Körver-Keularts, IMLW; Martens, J; Mecinović, J; Merx, J; Oomens, J; Rutjes, FPJT; van Outersterp, RE; Waterval, HWAH; Wevers, RA1
Bian, X; Fang, Y; Li, N; Li, Y; Wang, X; Wu, JL; Zhang, X; Zhao, Y; Zhou, N; Zhou, T1
Bordenave-Jacquemin, M; Cabassa-Hourton, C; Carol, P; Clément, G; Crilat, E; Dacher, M; Dourmap, C; Durand, N; Guivarc'h, A; Lebreton, S; Planchais, S; Savouré, A; Zheng, Y1
Ahmad, A; Ahmad, R; Bastola, DK; Becker, DF; Dhawan, P; Kumar, B; Kumar, V; Lama Tamang, R; Patel, SM; Singh, AB; Thapa, I1
An, F; Cui, B; He, B; Huang, Y; Kelley, KW; Lam, EW; Liu, Q; Lu, J; Luo, H; Luo, Y; Peng, F; Su, K; Wang, C; Wang, H; Wang, L; Yang, Y; Zhang, X; Zhang, Y; Zhao, Z1

Reviews

4 review(s) available for delta-1-pyrroline-5-carboxylate and proline

ArticleYear
The regulatory functions of proline and pyrroline-5-carboxylic acid.
    Current topics in cellular regulation, 1985, Volume: 25

    Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship

1985
Proline and hydroxyproline metabolism: implications for animal and human nutrition.
    Amino acids, 2011, Volume: 40, Issue:4

    Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Birds; Chickens; Collagen; Diet; Dietary Supplements; Fishes; Glutamic Acid; Glutamine; Humans; Hydroxyproline; Infant; Infant, Newborn; Milk; Nutritional Requirements; Proline; Pyrroles; Swine

2011
L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application.
    Applied microbiology and biotechnology, 2012, Volume: 93, Issue:1

    Topics: Amino Acid Sequence; Archaea; Coenzymes; Models, Molecular; Molecular Sequence Data; Proline; Proline Oxidase; Protein Multimerization; Protein Subunits; Pyrroles

2012
P5C as an Interface of Proline Interconvertible Amino Acids and Its Role in Regulation of Cell Survival and Apoptosis.
    International journal of molecular sciences, 2021, Oct-29, Volume: 22, Issue:21

    Topics: Amino Acids; Animals; Apoptosis; Cell Survival; Humans; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles

2021

Other Studies

61 other study(ies) available for delta-1-pyrroline-5-carboxylate and proline

ArticleYear
Enzymes metabolizing delta1-pyrroline-5-carboxylate in rat tissues.
    The Biochemical journal, 1977, Jul-15, Volume: 166, Issue:1

    Topics: Animals; Fetus; Neoplasms, Experimental; Oxidoreductases; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Stereoisomerism; Temperature

1977
Possible involvement of a L-delta 1-pyrroline-5-carboxylate (P5C) reductase in the synthesis of proline in Desulfovibrio desulfuricans Norway.
    Biochemical and biophysical research communications, 1991, Sep-16, Volume: 179, Issue:2

    Topics: Desulfovibrio; DNA, Bacterial; Enzyme Stability; Escherichia coli; Gene Expression; Genotype; Hot Temperature; Plasmids; Proline; Pyrroles

1991
Proline is required for transcriptional control of the aromatic hydrocarbon-inducible P(1)450 gene in C57BL/6 mouse monolayer-cultured hepatocytes.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Mice; Mice, Inbred C57BL; Ornithine; Polycyclic Compounds; Proline; Pyrroles; RNA, Messenger; Transcription, Genetic

1991
Conversion of glutamate to ornithine and proline: pyrroline-5-carboxylate, a possible modulator of arginine requirements.
    The Journal of nutrition, 1985, Volume: 115, Issue:4

    Topics: Amino Acids; Animals; Arginine; Biotransformation; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Kidney; Liver; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Retinal Degeneration; Spleen

1985
Periodate oxidation products of hydroxylysine in the synthesis of 5-substituted prolines.
    Analytical biochemistry, 1985, May-15, Volume: 147, Issue:1

    Topics: Hydrogen-Ion Concentration; Hydroxylysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Periodic Acid; Proline; Pyrroles; Spectrophotometry, Infrared; Temperature

1985
The aqueous humor of rabbit contains high concentrations of pyrroline-5-carboxylate.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:10

    Topics: Animals; Aqueous Humor; Guinea Pigs; Haplorhini; Male; Models, Chemical; Pigmentation; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits; Species Specificity; Tissue Distribution

1986
Catalytic transfer of hydride ions from NADPH to oxygen by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
    Archives of biochemistry and biophysics, 1986, Volume: 248, Issue:1

    Topics: Adenosine Triphosphate; Animals; Humans; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxygen; Proline; Pyrroles; Rats

1986
Demonstration of a NADPH-linked delta 1-pyrroline-5-carboxylate-proline shuttle in a cell-free rat liver system.
    Biochimica et biophysica acta, 1986, Oct-29, Volume: 884, Issue:1

    Topics: Animals; Cell-Free System; Cold Temperature; Mitochondria, Liver; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Solubility

1986
Stimulation of the hexose monophosphate pathway by pyrroline-5-carboxylate reductase in the lens.
    Experimental eye research, 1985, Volume: 41, Issue:6

    Topics: Aging; Animals; Female; Glucose; Glutamine; Lens, Crystalline; Male; Mice; Mice, Inbred Strains; Ornithine; Oxidoreductases Acting on CH-NH Group Donors; Pentose Phosphate Pathway; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains

1985
Reversible reduction of an alpha-imino acid to an alpha-amino acid catalyzed by glutamate dehydrogenase: effect of ionizable functional groups.
    Biochemistry, 1985, Jan-29, Volume: 24, Issue:3

    Topics: Animals; Cattle; Glutamate Dehydrogenase; Kinetics; Liver; Mathematics; NADP; Oxidation-Reduction; Proline; Pyrroles

1985
A radioisotopic assay for delta 1-pyrroline-5-carboxylate synthase activity.
    Enzyme, 1984, Volume: 31, Issue:2

    Topics: Animals; Carbon Radioisotopes; Cell Line; Cricetinae; Glutamates; Glutamic Acid; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Transaminases

1984
Transfer of reducing equivalents into mitochondria by the interconversions of proline and delta 1-pyrroline-5-carboxylate.
    Archives of biochemistry and biophysics, 1983, Volume: 225, Issue:1

    Topics: Animals; Catalysis; Cell-Free System; Cytosol; Glucose; Glucosephosphate Dehydrogenase; Humans; In Vitro Techniques; Male; Mitochondria, Liver; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rats; Rats, Inbred Strains

1983
Pyrroline-5-carboxylate in human plasma.
    Metabolism: clinical and experimental, 1984, Volume: 33, Issue:8

    Topics: Chromatography, Ion Exchange; Female; Humans; Male; Methods; Proline; Pyrroles; Saliva

1984
The intercellular proline cycle.
    Life sciences, 1981, Jan-05, Volume: 28, Issue:1

    Topics: Animals; Erythrocytes; Humans; Liver; Mice; Mitochondria, Liver; NADP; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases

1981
Stimulation of the hexosemonophosphate-pentose pathway by pyrroline-5-carboxylate in cultured cells.
    Journal of cellular physiology, 1982, Volume: 110, Issue:3

    Topics: Animals; Cell Line; Cells, Cultured; Citric Acid Cycle; Cricetinae; Female; Fibroblasts; Glucose; Hexosephosphates; Humans; Kidney; NADP; Ovary; Oxidation-Reduction; Pentoses; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Rabbits

1982
Transfer of 1-pyrroline-5-carboxylate as oxidizing potential from hepatocytes to erythrocytes.
    The Biochemical journal, 1982, Jan-15, Volume: 202, Issue:1

    Topics: Animals; Erythrocytes; Humans; In Vitro Techniques; Liver; Male; Oxidation-Reduction; Pentosephosphates; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Inbred Strains; Stimulation, Chemical

1982
Disease of the ornithine-proline pathway: delta 1-pyrroline-5-carboxylate reductase deficiency in the retina of retinal degeneration mice.
    Metabolic, pediatric, and systemic ophthalmology, 1982, Volume: 6, Issue:2

    Topics: Animals; Cattle; Eye; Liver; Mice; Mice, Inbred Strains; Ornithine; Ornithine Carbamoyltransferase; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; Retinal Degeneration; Weaning

1982
Proline is biosynthesized from arginine in Staphylococcus aureus.
    Microbiology (Reading, England), 1996, Volume: 142 ( Pt 6)

    Topics: Arginine; Bacterial Proteins; Carbon; DNA Transposable Elements; Glutamic Acid; Ornithine; Proline; Pyrroles; Staphylococcus aureus

1996
Reciprocal regulation of delta 1-pyrroline-5-carboxylate synthetase and proline dehydrogenase genes controls proline levels during and after osmotic stress in plants.
    Molecular & general genetics : MGG, 1996, Dec-13, Volume: 253, Issue:3

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Sequence; Animals; Arabidopsis; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genetic Complementation Test; Molecular Sequence Data; Osmotic Pressure; Oxidoreductases Acting on CH-NH Group Donors; Proline; Proline Oxidase; Pyrroles; RNA, Messenger; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Transcription, Genetic; Water

1996
The PutA protein of Salmonella typhimurium catalyzes the two steps of proline degradation via a leaky channel.
    Archives of biochemistry and biophysics, 1998, Jun-15, Volume: 354, Issue:2

    Topics: Bacterial Proteins; Binding, Competitive; Catalysis; Kinetics; Membrane Proteins; NAD; Proline; Proline Oxidase; Pyrroles; Salmonella typhimurium; Substrate Specificity

1998
Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: Aldehydes; Avitaminosis; Chromatography, High Pressure Liquid; Humans; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Proline; Pyridoxal Phosphate; Pyridoxine; Pyrroles; Seizures

2001
A novel pyrroline-5-carboxylic acid and acetoacetic acid adduct in hyperprolinaemia type II.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 331, Issue:1-2

    Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Child; Female; Gas Chromatography-Mass Spectrometry; Humans; Proline; Pyridoxal Phosphate; Pyrroles; Stereoisomerism

2003
On the biosynthesis of proline in Neurospora crassa: enzymic reduction of delta1-pyrroline-5-carboxylate.
    Biochimica et biophysica acta, 1955, Volume: 17, Issue:4

    Topics: Neurospora; Neurospora crassa; Proline; Pyrroles

1955
Characterization of an enzyme reducing pyrroline-5-carboxylate to proline.
    Nature, 1956, Jun-16, Volume: 177, Issue:4520

    Topics: Humans; Liver; Oxidoreductases; Proline; Pyrroles

1956
Hydroxyproline metabolism. II. Enzymatic preparation and properties of Delta 1-pyrroline-3-hydroxy-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. III. Enzymatic synthesis of hydroxyproline from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Hydroxyproline; Proline; Pyrroles

1960
Hydroxyproline metabolism. IV. Enzymatic synthesis of gamma-hydroxyglutamate from Delta 1-pyrroline-3-hydroxy-5-carboxylate.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Amino Acids; Glutamates; Hydroxyproline; Proline; Pyrroles

1960
The interconversion of glutamic acid and proline. II. The preparation and properties of delta 1-pyrroline-5-carboxylic acid.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1960
The interconversion of glutamic acid and proline. V. The reduction of delta 1-pyrroline-5-carboxylic acid to proline.
    The Journal of biological chemistry, 1962, Volume: 237

    Topics: Carboxylic Acids; Glutamates; Glutamic Acid; Proline; Pyrroles

1962
Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.
    Biochimica et biophysica acta, 2004, Nov-18, Volume: 1675, Issue:1-3

    Topics: Animals; Glutamic Acid; Liver; Male; Mitochondria; NADP; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Rats; Rats, Sprague-Dawley; Rotenone; Subcellular Fractions; Ultracentrifugation

2004
Unraveling delta1-pyrroline-5-carboxylate-proline cycle in plants by uncoupled expression of proline oxidation enzymes.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Arabidopsis; Arabidopsis Proteins; Droughts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamic Acid; Hot Temperature; Medicago sativa; Mitochondria; Mutation; Nicotiana; Oxidation-Reduction; Plants; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Chloride

2009
L-Proline nutrition and catabolism in Staphylococcus saprophyticus.
    Antonie van Leeuwenhoek, 2011, Volume: 99, Issue:4

    Topics: Arginine; Cell Membrane; Culture Media; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Pyrroles; Pyrroline Carboxylate Reductases; Staphylococcus saprophyticus

2011
Defect in proline synthesis: pyrroline-5-carboxylate reductase 1 deficiency leads to a complex clinical phenotype with collagen and elastin abnormalities.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:3

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Collagen; delta-1-Pyrroline-5-Carboxylate Reductase; DNA Mutational Analysis; Elastin; Family; Female; Humans; Infant; Male; Metabolism, Inborn Errors; Middle Aged; Models, Biological; Mutation, Missense; Phenotype; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Young Adult

2011
Elevation of free proline and proline-rich protein levels by simultaneous manipulations of proline biosynthesis and degradation in plants.
    Plant science : an international journal of experimental plant biology, 2011, Volume: 181, Issue:2

    Topics: Arabidopsis; Bacterial Proteins; Cell Wall; Chloroplasts; Cytosol; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Medicago sativa; Mutation; Nicotiana; Phosphotransferases (Carboxyl Group Acceptor); Plant Proteins; Plants, Genetically Modified; Proline; Proline Oxidase; Pyrroles; RNA, Antisense; RNA, Plant; Salinity; Stress, Physiological

2011
Ornithine-delta-aminotransferase and proline dehydrogenase genes play a role in non-host disease resistance by regulating pyrroline-5-carboxylate metabolism-induced hypersensitive response.
    Plant, cell & environment, 2012, Volume: 35, Issue:7

    Topics: Arabidopsis; Disease Resistance; Gene Expression Regulation, Plant; Gene Silencing; Mitochondria; Nicotiana; Ornithine-Oxo-Acid Transaminase; Plant Proteins; Proline; Proline Oxidase; Pseudomonas syringae; Pyrroles; Reactive Oxygen Species

2012
A network perspective on metabolic inconsistency.
    BMC systems biology, 2012, May-14, Volume: 6

    Topics: Adenoma; Adipates; Adrenal Glands; Aldosterone; Humans; Metabolic Networks and Pathways; Proline; Pyrroles; Systems Biology; Transcriptome

2012
A study of proline metabolism in canola (Brassica napus L.) seedlings under salt stress.
    Molecules (Basel, Switzerland), 2012, May-16, Volume: 17, Issue:5

    Topics: Brassica napus; Gene Expression Regulation, Plant; Phosphotransferases (Alcohol Group Acceptor); Plant Roots; Plant Shoots; Proline; Proline Oxidase; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Salinity; Salt Tolerance; Seedlings; Sodium Chloride

2012
The proline metabolism intermediate Δ1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast.
    FEBS letters, 2012, Jul-30, Volume: 586, Issue:16

    Topics: Anions; Cell Death; Dose-Response Relationship, Drug; Gene Expression Regulation, Fungal; Mitochondria; Models, Biological; Oxidative Stress; Oxygen Consumption; Proline; Pyrroles; Reactive Oxygen Species; Saccharomyces cerevisiae; Superoxides; Time Factors

2012
A novel Δ(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation.
    Journal of plant physiology, 2013, Feb-15, Volume: 170, Issue:3

    Topics: Gene Expression Regulation, Plant; Medicago truncatula; Nitrogen; Nitrogen Fixation; Ornithine-Oxo-Acid Transaminase; Plant Growth Regulators; Proline; Pyrroles; Stress, Physiological; Symbiosis

2013
Role of the putative osmosensor Arabidopsis histidine kinase1 in dehydration avoidance and low-water-potential response.
    Plant physiology, 2013, Volume: 161, Issue:2

    Topics: Abscisic Acid; Adaptation, Physiological; Arabidopsis; Arabidopsis Proteins; Blotting, Western; Dehydration; Dioxygenases; Gene Expression Regulation, Plant; Ligases; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; Mutation; Osmolar Concentration; Plant Stomata; Plant Transpiration; Proline; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; Water; Water-Electrolyte Balance

2013
Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.
    Environmental microbiology, 2014, Volume: 16, Issue:3

    Topics: Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Base Sequence; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutation; Proline; Promoter Regions, Genetic; Pyrroles; Sequence Alignment; Trans-Activators

2014
Effect of drought and combined drought and heat stress on polyamine metabolism in proline-over-producing tobacco plants.
    Plant physiology and biochemistry : PPB, 2013, Volume: 73

    Topics: Adaptation, Physiological; Arabidopsis Proteins; Droughts; Genes, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Hot Temperature; Malondialdehyde; Multienzyme Complexes; Nicotiana; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Phosphotransferases (Alcohol Group Acceptor); Plant Leaves; Plant Proteins; Plant Roots; Polyamine Oxidase; Polyamines; Proline; Putrescine; Pyrroles; Spermidine; Spermine; Transformation, Genetic; Water

2013
Context of action of proline dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis.
    BMC plant biology, 2014, Jan-13, Volume: 14

    Topics: Arabidopsis; Arabidopsis Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Proline; Proline Oxidase; Pyrroles; Reactive Oxygen Species

2014
Exogenous proline application ameliorates toxic effects of arsenate in Solanum melongena L. seedlings.
    Ecotoxicology and environmental safety, 2015, Volume: 117

    Topics: Antioxidants; Arsenates; Catalase; Chlorophyll; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Photosynthesis; Photosystem II Protein Complex; Proline; Pyrroles; Reactive Oxygen Species; Seedlings; Solanum melongena; Superoxide Dismutase

2015
An Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma brucei.
    PLoS pathogens, 2015, Volume: 11, Issue:5

    Topics: Biological Transport; Cell Proliferation; Drug Resistance, Multiple; Energy Metabolism; Gene Expression Regulation; Gene Knockout Techniques; Membrane Potential, Mitochondrial; Metabolomics; Mitochondria; Mitochondrial Membrane Transport Proteins; Parasitic Sensitivity Tests; Pentamidine; Proline; Protein Structure, Tertiary; Protozoan Proteins; Pyrroles; Recombinant Proteins; RNA Interference; Trypanocidal Agents; Trypanosoma brucei brucei

2015
Grassland species differentially regulate proline concentrations under future climate conditions: an integrated biochemical and modelling approach.
    The New phytologist, 2015, Volume: 208, Issue:2

    Topics: Climate; Glutamic Acid; Grassland; Metabolic Networks and Pathways; Models, Biological; Monte Carlo Method; Ornithine; Proline; Pyrroles; RNA, Messenger; Species Specificity; Thermodynamics

2015
Interaction of Mg with heavy metals (Cu, Cd) in T. aestivum with special reference to oxidative and proline metabolism.
    Journal of plant research, 2016, Volume: 129, Issue:3

    Topics: Ascorbate Peroxidases; Carotenoids; Catalase; Chlorophyll; Chlorophyll A; Hydrogen Peroxide; Magnesium; Malondialdehyde; Metals, Heavy; Oxidation-Reduction; Plant Roots; Plant Shoots; Proline; Pyrroles; Superoxide Dismutase; Triticum

2016
Manganese-induced regulations in growth, yield formation, quality characters, rice aroma and enzyme involved in 2-acetyl-1-pyrroline biosynthesis in fragrant rice.
    Plant physiology and biochemistry : PPB, 2016, Volume: 103

    Topics: Gene Expression Regulation, Plant; Manganese; Ornithine-Oxo-Acid Transaminase; Oryza; Plant Proteins; Proline; Proline Oxidase; Pyrroles; Seeds

2016
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA.
    Bioscience reports, 2016, Volume: 36, Issue:6

    Topics: Bacterial Proteins; Chimera; DNA-Binding Proteins; Escherichia coli; Membrane Proteins; Proline; Proline Oxidase; Protein Binding; Protein Domains; Pyrroles; Rhodobacter capsulatus

2016
Proline Accumulation Is Regulated by Transcription Factors Associated with Phosphate Starvation.
    Plant physiology, 2017, Volume: 175, Issue:1

    Topics: Abscisic Acid; Arabidopsis; Arabidopsis Proteins; Binding Sites; Glutamate-5-Semialdehyde Dehydrogenase; Multienzyme Complexes; Mutation; Phosphates; Phosphotransferases (Alcohol Group Acceptor); Plant Growth Regulators; Proline; Promoter Regions, Genetic; Pyrroles; Signal Transduction; Transcription Factors; Transcriptional Activation

2017
An Ancestral Allele of
    Plant physiology, 2018, Volume: 178, Issue:2

    Topics: Adaptation, Physiological; Alleles; Arabidopsis; Chromosome Mapping; Chromosomes, Plant; Droughts; Hordeum; Plant Roots; Proline; Pyrroles; Quantitative Trait Loci; Water

2018
Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana.
    PloS one, 2019, Volume: 14, Issue:1

    Topics: Arabidopsis; Arabidopsis Proteins; Arginine; Biosynthetic Pathways; Carbon Dioxide; Citrulline; Gene Expression Regulation, Plant; Genes, Plant; Light; Models, Biological; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Pyrroles; RNA, Plant; Stress, Physiological; Sucrose; Urea

2019
Characterization and expression analysis of P5CS (Δ1-pyrroline-5-carboxylate synthase) gene in two distinct populations of the Atlantic Forest native species Eugenia uniflora L.
    Molecular biology reports, 2020, Volume: 47, Issue:2

    Topics: Aldehyde Dehydrogenase; Droughts; Eugenia; Gene Expression Regulation, Plant; Glutamate-5-Semialdehyde Dehydrogenase; Ligases; Multienzyme Complexes; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Plants; Proline; Pyrroles; Stress, Physiological

2020
Selenium-silicon (Se-Si) induced modulations in physio-biochemical responses, grain yield, quality, aroma formation and lodging in fragrant rice.
    Ecotoxicology and environmental safety, 2020, Jun-15, Volume: 196

    Topics: Antioxidants; Dose-Response Relationship, Drug; Edible Grain; Malondialdehyde; Odorants; Oryza; Proline; Pyrroles; Selenium; Silicon; Soil

2020
Trypanosoma cruzi synthesizes proline via a Δ1-pyrroline-5-carboxylate reductase whose activity is fine-tuned by NADPH cytosolic pools.
    The Biochemical journal, 2020, 05-29, Volume: 477, Issue:10

    Topics: Cytosol; Electron Transport; Glutamic Acid; Mitochondria; NADP; Oxidation-Reduction; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Trypanosoma cruzi

2020
Kinetics of human pyrroline-5-carboxylate reductase in L-thioproline metabolism.
    Amino acids, 2021, Volume: 53, Issue:12

    Topics: Binding Sites; Cysteine; Humans; Kinetics; Proline; Pyrroles; Pyrroline Carboxylate Reductases; Thiazolidines

2021
Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II.
    Communications biology, 2022, 09-21, Volume: 5, Issue:1

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Biomarkers; Phosphates; Proline; Proline Oxidase; Pyridoxal; Pyrroles

2022
Identification of proline, 1-pyrroline-5-carboxylate and glutamic acid as biomarkers of depression reflecting brain metabolism using carboxylomics, a new metabolomics method.
    Psychiatry and clinical neurosciences, 2023, Volume: 77, Issue:4

    Topics: Animals; Biomarkers; Brain; Depression; Glutamic Acid; Humans; Metabolomics; Proline; Rats

2023
Pyrroline-5-carboxylate dehydrogenase is an essential enzyme for proline dehydrogenase function during dark-induced senescence in Arabidopsis thaliana.
    Plant, cell & environment, 2023, Volume: 46, Issue:3

    Topics: Amino Acids; Arabidopsis; Arginine; Glutamates; Ornithine; Proline; Proline Oxidase

2023
Pyrroline-5-Carboxylate Reductase-2 Promotes Colorectal Carcinogenesis by Modulating Microtubule-Associated Serine/Threonine Kinase-like/Wnt/β-Catenin Signaling.
    Cells, 2023, 07-18, Volume: 12, Issue:14

    Topics: beta Catenin; Carcinogenesis; Chromatography, Liquid; Colonic Neoplasms; Humans; Microtubule-Associated Proteins; Microtubules; Oxidoreductases; Proline; Protein Serine-Threonine Kinases; Serine; Tandem Mass Spectrometry; Wnt Signaling Pathway

2023
Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress.
    Cell death & disease, 2023, 10-16, Volume: 14, Issue:10

    Topics: Breast Neoplasms; delta-1-Pyrroline-5-Carboxylate Reductase; Female; Humans; Neoplasm Recurrence, Local; Oxidoreductases; Proline

2023