delavirdine-mesylate and loviride

delavirdine-mesylate has been researched along with loviride* in 1 studies

Other Studies

1 other study(ies) available for delavirdine-mesylate and loviride

Article	Year
Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU). Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17 Stemming from work on a previous clinical candidate, loviride, and other alpha-APA derivatives, a new series of potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) has been synthesized. The ITU analogues, which contain a unique diarylated imidoyl thiourea, are very active in inhibiting both wild-type and clinically important mutant strains of HIV-1. Topics: Acetamides; Acetophenones; Aniline Compounds; Anti-HIV Agents; Drug Design; Drug Evaluation, Preclinical; Drug Stability; HIV Reverse Transcriptase; HIV-1; Imines; Structure-Activity Relationship; Thiourea	2001

Article

Year

Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU).

Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

Stemming from work on a previous clinical candidate, loviride, and other alpha-APA derivatives, a new series of potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) has been synthesized. The ITU analogues, which contain a unique diarylated imidoyl thiourea, are very active in inhibiting both wild-type and clinically important mutant strains of HIV-1.

Topics: Acetamides; Acetophenones; Aniline Compounds; Anti-HIV Agents; Drug Design; Drug Evaluation, Preclinical; Drug Stability; HIV Reverse Transcriptase; HIV-1; Imines; Structure-Activity Relationship; Thiourea

2001