Page last updated: 2024-08-16

delavirdine and didanosine

delavirdine has been researched along with didanosine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (52.17)18.2507
2000's5 (21.74)29.6817
2010's5 (21.74)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Bachmann, MH; Fessel, WJ; Kagan, RM; Mitsuya, Y; Shafer, RW; Shahriar, R; Varghese, V1
Balzarini, J; Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yan, ZH1
Balzarini, J; Chen, X; De Clercq, E; Li, Z; Liu, H; Liu, X; Pannecouque, C; Xie, Z; Zhan, P; Zhang, L; Zhao, T1
Chen, FE; Chen, WX; Daelemans, D; De Clercq, E; He, QQ; Pannecouque, C; Wu, HQ; Yao, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buckheit, RW; Cushman, M; Hartman, TL; Hoshi, A; Okazaki, M; Pannecouque, C; Sakamoto, T; Takayama, J; Xuan, M1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Boyle, J; Chaitt, DG; Coleman, S; Cox, SR; Daenzer, CL; Davey, RT; Eastman, PS; Falloon, J; Freimuth, WW; Herpin, BR; Kovacs, JA; Lane, HC; Masur, H; Metcalf, JA; Polis, MA; Reed, GF; Walker, RE; Wathen, L1
Cox, SR; DeRemer, M; Driver, M; Fischl, MA; Freimuth, WW; Morse, GD; Shelton, MJ1
Berrios, L; Cox, S; Demeter, LM; Dexter, A; Freimuth, W; Gerondelis, P; Meehan, PM; Morse, G; Reichman, RC1
Chong, KT; Pagano, PJ1
Saag, MS; Schooley, RT1
Bassett, R; Connick, E; Demeter, L; Fischl, M; Freimuth, W; Friedland, GH; Griffith, B; Hirsch, M; Hughes, M; Morse, G; Nevin, T; Pollard, R1
Temesgen, Z; Wright, AJ1
Freimuth, WW; Glick, HA; Schulman, KA; Weinfurt, KP; Willke, RJ1
Smart, T; Torres, G1
Mascolini, M1
James, JS1
Atkinson, MJ; Frangakis, C; Huang, IC; Lenderking, WR; Willke, RJ; Wu, AW1

Reviews

3 review(s) available for delavirdine and didanosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiretroviral chemotherapy.
    Current clinical topics in infectious diseases, 1998, Volume: 18

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Ritonavir; Saquinavir; Stavudine; Zalcitabine; Zidovudine

1998
Antiretrovirals.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cyclopropanes; Delavirdine; Didanosine; Dideoxynucleosides; Female; Furans; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Oxazines; Pregnancy; Pregnancy Complications, Infectious; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Stavudine; Sulfonamides; Zalcitabine; Zidovudine

1999

Trials

5 trial(s) available for delavirdine and didanosine

ArticleYear
Randomized, controlled phase I/II, trial of combination therapy with delavirdine (U-90152S) and conventional nucleosides in human immunodeficiency virus type 1-infected patients.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:7

    Topics: Adult; Anti-HIV Agents; Biological Availability; Delavirdine; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Indoles; Male; Middle Aged; Piperazines; Reverse Transcriptase Inhibitors; Zidovudine

1996
Single-dose pharmacokinetics of delavirdine mesylate and didanosine in patients with human immunodeficiency virus infection.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Cross-Over Studies; Delavirdine; Didanosine; Drug Interactions; Drug Therapy, Combination; Female; HIV-1; Humans; Indoles; Male; Piperazines

1997
Efficacy and safety of delavirdine mesylate with zidovudine and didanosine compared with two-drug combinations of these agents in persons with HIV disease with CD4 counts of 100 to 500 cells/mm3 (ACTG 261). ACTG 261 Team.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21, Issue:4

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Male; Reverse Transcriptase Inhibitors; RNA, Viral; Safety; Zidovudine

1999
Relationship between CD4 count, viral burden, and quality of life over time in HIV-1-infected patients.
    Medical care, 2000, Volume: 38, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; Health Status Indicators; HIV Infections; HIV-1; Humans; Male; Middle Aged; Quality of Life; RNA, Viral; Viral Load

2000
US and UK versions of the EQ-5D preference weights: does choice of preference weights make a difference?
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2007, Volume: 16, Issue:6

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Delavirdine; Didanosine; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Male; Patient Satisfaction; Psychometrics; Quality of Life; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Sickness Impact Profile; United Kingdom; United States; Viral Load

2007

Other Studies

15 other study(ies) available for delavirdine and didanosine

ArticleYear
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Human immunodeficiency virus type 1 isolates with the reverse transcriptase (RT) mutation Q145M retain nucleoside and nonnucleoside RT inhibitor susceptibility.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Amino Acid Sequence; Anti-HIV Agents; Drug Resistance, Viral; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Nucleosides; Phenotype; Reverse Transcriptase Inhibitors

2009
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies.
    Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

    Topics: Binding Sites; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2013
Design, synthesis and preliminary SAR studies of novel N-arylmethyl substituted piperidine-linked aniline derivatives as potent HIV-1 NNRTIs.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Aniline Compounds; Anti-HIV Agents; Drug Design; HIV-1; Humans; Models, Molecular; Piperidines; Structure-Activity Relationship

2014
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry, 2015, Feb-01, Volume: 23, Issue:3

    Topics: Anti-HIV Agents; Binding Sites; Cell Line; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Pyrimidines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2015
Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy.
    Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13

    Topics: Anti-HIV Agents; Drug Stability; Esters; HIV-1; Humans; Inhibitory Concentration 50; Methane; Models, Molecular; Reverse Transcriptase Inhibitors

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
[A new AIDS drug in evaluation].
    Fortschritte der Medizin, 1993, Aug-30, Volume: 111, Issue:24

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Delavirdine; Didanosine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; Zidovudine

1993
HIV-1 drug susceptibilities and reverse transcriptase mutations in patients receiving combination therapy with didanosine and delavirdine.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Feb-01, Volume: 14, Issue:2

    Topics: Adult; Anti-HIV Agents; Delavirdine; Didanosine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Male; Mutation; Phenotype; Piperazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load; Zidovudine

1997
Inhibition of human immunodeficiency virus type 1 infection in vitro by combination of delavirdine, zidovudine and didanosine.
    Antiviral research, 1997, Volume: 34, Issue:1

    Topics: Anti-HIV Agents; Cell Line; Delavirdine; Didanosine; DNA, Viral; HIV-1; Humans; Indoles; Piperazines; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Zidovudine

1997
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 1997, Dec-12, Volume: 39, Issue:1015

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Delavirdine; Diarrhea; Didanosine; Drug Interactions; Drug Therapy, Combination; HIV Infections; Humans; Indinavir; Lamivudine; Nelfinavir; Nevirapine; Protease Inhibitors; Reverse Transcriptase Inhibitors; Ritonavir; Saquinavir; Virus Replication; Zalcitabine; Zidovudine

1997
Antiviral roundup.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1996, Volume: 10, Issue:8

    Topics: CD4 Lymphocyte Count; Cohort Studies; Delavirdine; Didanosine; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Mutation; Piperazines; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Zidovudine

1996
FDA advisory committee deadlocks on delavirdine. Food and Drug Administration.
    AIDS treatment news, 1996, Dec-06, Issue:No 260

    Topics: Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Delavirdine; Didanosine; Disease Progression; Drug Approval; Drug Industry; Drug Interactions; Drug Therapy, Combination; HIV Infections; HIV Protease Inhibitors; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Viral Load; Zidovudine

1996
Delavirdine (Rescriptor) approved.
    AIDS treatment news, 1997, Apr-18, Issue:No 269

    Topics: Anti-HIV Agents; Delavirdine; Didanosine; Drug Approval; Drug Costs; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indoles; Piperazines; Reverse Transcriptase Inhibitors; United States; United States Food and Drug Administration; Zidovudine

1997
Drugs for HIV infection.
    The Medical letter on drugs and therapeutics, 2001, Nov-26, Volume: 43, Issue:1119

    Topics: Alkynes; Benzoxazines; Cyclopropanes; Delavirdine; Didanosine; Dose-Response Relationship, Drug; HIV Infections; HIV Protease Inhibitors; Humans; Nelfinavir; Nevirapine; Oxazines; Reverse Transcriptase Inhibitors; Saquinavir; Stavudine; Zidovudine

2001