Compounds > dehydroxymethylepoxyquinomicin

dehydroxymethylepoxyquinomicin and hydroquinone

dehydroxymethylepoxyquinomicin has been researched along with hydroquinone* in 1 studies

Other Studies

1 other study(ies) available for dehydroxymethylepoxyquinomicin and hydroquinone

Article	Year
A chemo-enzymatic expeditious route to racemic dihexanoyl (2R,3R,4R)-dehydroxymethylepoxyquinomycin (DHMEQ), the precursor for lipase-catalyzed synthesis of the potent nuclear factor-κB inhibitor, (2S,3S,4S)-DHMEQ. Chemical & pharmaceutical bulletin, 2012, Volume: 60, Issue:9* In order to synthesize the potent nuclear factor (NF)-κB inhibitor, (2S,3S,4S)-dehydroxymethylepoxyquinomycin (DHMEQ), in a large scale, a new route for its corresponding racemic precursor, dihexanoyl (2R,3R,4R*)-DHMEQ, was developed. By employing both hydroquinone and benzoquinone intermediates, the total yield, reproducibility, and synthetic steps were improved and the synthetic cost was reduced. Topics: Benzamides; Benzoquinones; Burkholderia cepacia; Catalysis; Cyclohexanones; Hydroquinones; I-kappa B Proteins; Lipase; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Stereoisomerism	2012

Article

Year

A chemo-enzymatic expeditious route to racemic dihexanoyl (2R*,3R*,4R*)-dehydroxymethylepoxyquinomycin (DHMEQ), the precursor for lipase-catalyzed synthesis of the potent nuclear factor-κB inhibitor, (2S,3S,4S)-DHMEQ.

Chemical & pharmaceutical bulletin, 2012, Volume: 60, Issue:9

In order to synthesize the potent nuclear factor (NF)-κB inhibitor, (2S,3S,4S)-dehydroxymethylepoxyquinomycin (DHMEQ), in a large scale, a new route for its corresponding racemic precursor, dihexanoyl (2R*,3R*,4R*)-DHMEQ, was developed. By employing both hydroquinone and benzoquinone intermediates, the total yield, reproducibility, and synthetic steps were improved and the synthetic cost was reduced.

Topics: Benzamides; Benzoquinones; Burkholderia cepacia; Catalysis; Cyclohexanones; Hydroquinones; I-kappa B Proteins; Lipase; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Stereoisomerism

2012