Page last updated: 2024-08-23

dehydroretronecine and senecionine

dehydroretronecine has been researched along with senecionine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buhler, DR; Guengerich, FP; Miranda, CL; Reed, RL1
Buhler, DR; Kedzierski, B; Miranda, CL; Reed, RL1
Buhler, DR; Kedzierski, B1
Buhler, DR; Chung, WG1
Buhler, DR; Craig, AM; Duringer, JM1

Other Studies

5 other study(ies) available for dehydroretronecine and senecionine

ArticleYear
Role of cytochrome P450IIIA4 in the metabolism of the pyrrolizidine alkaloid senecionine in human liver.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Carcinogens; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Immunoglobulin G; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Monocrotaline; Norpregnenes; Oxidation-Reduction; Pyrrolizidine Alkaloids; Troleandomycin

1991
Mechanisms for pyrrolizidine alkaloid activation and detoxification.
    Advances in experimental medicine and biology, 1991, Volume: 283

    Topics: Animals; Biotransformation; Glutathione; In Vitro Techniques; Inactivation, Metabolic; Male; Microsomes, Liver; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

1991
The formation of 6,7-dihydro-7-hydroxy-1-hydroxy-methyl-5H-pyrrolizine, a metabolite of pyrrolizidine alkaloids.
    Chemico-biological interactions, 1986, Volume: 57, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Circular Dichroism; In Vitro Techniques; Male; Mass Spectrometry; Microsomes, Liver; Monocrotaline; Pyrrolizidine Alkaloids; Rats

1986
The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs.
    Toxicology and applied pharmacology, 1994, Volume: 127, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Male; Microsomes, Liver; Monocrotaline; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pyrrolizidine Alkaloids; Rats; Rats, Sprague-Dawley; Species Specificity; Spironolactone

1994
Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.
    American journal of veterinary research, 2004, Volume: 65, Issue:11

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cattle; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Glutathione; Microsomes, Liver; Monocrotaline; Oxidoreductases, N-Demethylating; Oxygenases; Pyrrolizidine Alkaloids; Sheep; Species Specificity

2004