Page last updated: 2024-08-23

dehydroretronecine and riddelliine n-oxide

dehydroretronecine has been researched along with riddelliine n-oxide in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, PC; Chou, MW; Doerge, DR; Fu, PP; Yan, J; Yang, YC1
Chou, MW; Churchwell, M; Doerge, DR; Fu, PP; Jian, Y; Williams, LD; Xia, Q1
Beger, RD; Chou, MW; Doerge, DR; Fu, PP; Wang, YP; Williams, LD; Yan, J; Yang, YC1
Chou, MW; Fu, PP; Wang, YP; Yan, J1
Chou, MW; Fu, PP; Xia, Q; Yan, J1

Other Studies

5 other study(ies) available for dehydroretronecine and riddelliine n-oxide

ArticleYear
Metabolic activation of the tumorigenic pyrrolizidine alkaloid, riddelliine, leading to DNA adduct formation in vivo.
    Chemical research in toxicology, 2001, Volume: 14, Issue:1

    Topics: Animals; Biotransformation; Carcinogens; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Isotope Labeling; Liver; Liver Neoplasms, Experimental; Microsomes, Liver; Monocrotaline; Phosphorus Radioisotopes; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344

2001
Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.
    Chemical research in toxicology, 2003, Volume: 16, Issue:9

    Topics: Adenine Nucleotides; Administration, Oral; Animals; Carcinogens; Cattle; DNA; DNA Adducts; Guanine Nucleotides; Isomerism; Liver; Micrococcal Nuclease; Monocrotaline; Phosphorus Radioisotopes; Pyrrolizidine Alkaloids; Rats; Spectrometry, Mass, Electrospray Ionization; Spleen; Thymine Nucleotides; Thymus Gland

2003
Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.
    Toxicology letters, 2003, Dec-10, Volume: 145, Issue:3

    Topics: Animals; Cattle; DNA; DNA Adducts; Female; Microsomes, Liver; Monocrotaline; Mutagens; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Thymus Gland

2003
Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Toxicology letters, 2005, Mar-15, Volume: 155, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; DNA Adducts; Female; Humans; Microsomes, Liver; Monocrotaline; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344

2005
Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
    Toxicology and industrial health, 2008, Volume: 24, Issue:3

    Topics: Animals; Biotransformation; Cyclic N-Oxides; DNA; DNA Adducts; Female; Liver; Microsomes, Liver; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344

2008