dehydrofelodipine has been researched along with felodipine in 9 studies
*Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. [MeSH]
*Felodipine: A dihydropyridine calcium antagonist with positive inotropic effects. It lowers blood pressure by reducing peripheral vascular resistance through a highly selective action on smooth muscle in arteriolar resistance vessels. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blychert, E | 1 |
| Arnold, JM; Bailey, DG; Munoz, C; Spence, JD | 1 |
| Arnold, JM; Bailey, DG; Bend, JR; Spence, JD; Tran, LT | 1 |
| Edgar, B; Johnsson, G; Lundahl, J; Regårdh, CG | 2 |
| Edgar, B; Johnsson, G; Lundahl, JU; Regårdh, CG | 1 |
| Bailey, DG; Carruthers, SG; Dresser, GK | 1 |
| Bailey, DG; Bend, JR; Dresser, GK; Freeman, DJ; Kreeft, JH; Munoz, C | 1 |
| Bailey, DG; Dresser, GK; Wacher, V; Wong, HT; Wong, S | 1 |
9 trial(s) available for dehydrofelodipine and felodipine
| Article | Year |
|---|---|
Felodipine pharmacokinetics and plasma concentration vs effect relationships.
Topics: Absorption; Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Biological Availability; Blood Pressure; Body Weight; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Sex Factors | 1992 |
Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin.
Topics: Adult; Beverages; Biological Availability; Citrus; Drug Interactions; Felodipine; Flavanones; Flavonoids; Humans; Male | 1993 |
Grapefruit juice-felodipine interaction: reproducibility and characterization with the extended release drug formulation.
Topics: Adult; Analysis of Variance; Beverages; Calcium Channel Blockers; Citrus; Cross-Over Studies; Delayed-Action Preparations; Felodipine; Food-Drug Interactions; Humans; Linear Models; Male; Reproducibility of Results; White People | 1995 |
Relationship between time of intake of grapefruit juice and its effect on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects.
Topics: Adult; Beverages; Blood Pressure; Calcium Channel Blockers; Citrus; Cross-Over Studies; Felodipine; Heart Rate; Humans; Male; Time Factors | 1995 |
Effects of grapefruit juice ingestion--pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men.
Topics: Administration, Oral; Adult; Beverages; Blood Pressure; Calcium Channel Blockers; Citrus; Cross-Over Studies; Drug Interactions; Felodipine; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Male; Tissue Distribution; Water | 1997 |
The interaction effect of grapefruit juice is maximal after the first glass.
Topics: Adult; Beverages; Blood Pressure; Calcium Channel Blockers; Citrus; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Synergism; Felodipine; Heart Rate; Humans; Male | 1998 |
Grapefruit juice--felodipine interaction in the elderly.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Area Under Curve; Beverages; Blood Pressure; Citrus; Diastole; Felodipine; Female; Food-Drug Interactions; Half-Life; Heart Rate; Humans; Male; Posture; Reference Values; Systole; Time Factors | 2000 |
Grapefruit-felodipine interaction: effect of unprocessed fruit and probable active ingredients.
Topics: Administration, Oral; Adult; Antioxidants; Area Under Curve; Beverages; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Delayed-Action Preparations; Drug Interactions; Felodipine; Female; Flavanones; Flavonoids; Furocoumarins; Half-Life; Humans; Male; Mixed Function Oxygenases; Radiation-Sensitizing Agents | 2000 |
Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Ascorbic Acid; Beverages; Biological Availability; Citrus; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Felodipine; Female; Humans; Male; Mentha piperita; Microsomes, Liver; Mixed Function Oxygenases; Plant Oils | 2002 |