dehydroevodiamine has been researched along with rutecarpine in 12 studies
| Studies (dehydroevodiamine) | Trials (dehydroevodiamine) | Recent Studies (post-2010) (dehydroevodiamine) | Studies (rutecarpine) | Trials (rutecarpine) | Recent Studies (post-2010) (rutecarpine) |
|---|---|---|---|---|---|
| 48 | 1 | 18 | 235 | 1 | 125 |
| Protein | Taxonomy | dehydroevodiamine (IC50) | rutecarpine (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.23 | |
| Cytochrome P450 1A1 | Homo sapiens (human) | 0.26 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 8.7 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.29 | |
| Cytochrome P450 1B1 | Homo sapiens (human) | 0.055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CF; Chiou, WF; Liao, JF | 1 |
| Chen, CF; Chen, TL; Guengerich, FP; Jan, WC; Lin, LC; Ueng, YF | 1 |
| Chen, CF; Chen, KT; Ko, HC; Ueng, YF; Wang, JJ | 1 |
| Decker, M | 1 |
| Brown, DA; Canning, MT; Galvin, JW; Nay, SL; Peña, AV; Yarosh, DB | 1 |
| Chen, CF; Chen, CM; Chen, KT; Ko, HC; Su, JP; Wang, GJ | 1 |
| Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH | 1 |
| Teng, J; Wang, Y; Xu, W; Yang, XW | 1 |
| Hu, CQ; Li, F; Yang, XW | 1 |
| Hu, CQ; Li, KK; Yang, XW | 1 |
| Bisson, WH; Gonzalez, FJ; Krausz, KW; Sun, D; Xie, C; Yagai, T; Yan, T; Yang, X; Zhang, L; Zhang, Y; Zheng, Y | 1 |
| Li, JJ; Tian, KM; Xu, SW | 1 |
1 review(s) available for dehydroevodiamine and rutecarpine
| Article | Year |
|---|---|
Rutaecarpine: A promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu).
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Evodia; Humans; Hypolipidemic Agents; Indole Alkaloids; Platelet Aggregation Inhibitors; Quinazolines; Vasodilator Agents | 2019 |
1 trial(s) available for dehydroevodiamine and rutecarpine
| Article | Year |
|---|---|
Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine.
Topics: Administration, Cutaneous; Adult; Alkaloids; Anti-Inflammatory Agents; Biomimetics; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Erythema; Evodia; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Indole Alkaloids; Keratinocytes; Middle Aged; Nicotinic Acids; Nitric Oxide; Plant Extracts; Quinazolines; Skin; Time Factors; Ultraviolet Rays | 2006 |
10 other study(ies) available for dehydroevodiamine and rutecarpine
| Article | Year |
|---|---|
Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa.
Topics: Alkaloids; Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indole Alkaloids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Vasodilator Agents | 1996 |
The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.
Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Indole Alkaloids; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Plant Extracts; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Theophylline | 2002 |
Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.
Topics: Alkaloids; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drugs, Chinese Herbal; Glucuronosyltransferase; Glutathione Transferase; Humans; Indole Alkaloids; Liver; Male; Methanol; Mice; Mice, Inbred C57BL; Oxazines; Plant Extracts; Plants, Medicinal; Quinazolines; Rutaceae | 2002 |
Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine.
Topics: Acetylcholinesterase; Alkaloids; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Indole Alkaloids; Quinazolines; Structure-Activity Relationship; Tacrine | 2005 |
Chemical and biological comparisons on Evodia with two related species of different locations and conditions.
Topics: Alkaloids; Animals; Aorta; China; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Evodia; Female; Fruit; In Vitro Techniques; Indole Alkaloids; Male; Methanol; Molecular Structure; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Species Specificity; Synephrine; Taiwan | 2006 |
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate | 2007 |
The permeability and the efflux of alkaloids of the Evodiae fructus in the Caco-2 model.
Topics: Alkaloids; Biological Transport, Active; Caco-2 Cells; Chromatography, High Pressure Liquid; Evodia; Humans; Indole Alkaloids; Intestinal Absorption; Permeability; Plant Extracts; Quinazolines | 2009 |
Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction.
Topics: Administration, Oral; Alkaloids; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Indole Alkaloids; Male; Molecular Structure; Quinazolines; Rats | 2012 |
New glycosidic alkaloid from the nearly ripe fruits of Euodia rutaecarpa.
Topics: Alkaloids; Drugs, Chinese Herbal; Evodia; Fruit; Indole Alkaloids; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Quinazolines | 2012 |
Structure-Activity Relationships of the Main Bioactive Constituents of
Topics: Alkaloids; Animals; Bile Acids and Salts; Cell Line, Tumor; Drugs, Chinese Herbal; Evodia; Genes, Reporter; Hep G2 Cells; Hepatocytes; Homeostasis; Humans; Indole Alkaloids; Liver; Male; Mice; Mice, Inbred C57BL; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Structure-Activity Relationship; Up-Regulation | 2018 |