Compounds > dehydroevodiamine

Page last updated: 2024-09-03

dehydroevodiamine and evodiamine

dehydroevodiamine has been researched along with evodiamine in 11 studies

Compound Research Comparison

Studies (dehydroevodiamine)	Trials (dehydroevodiamine)	Recent Studies (post-2010) (dehydroevodiamine)	Studies (evodiamine)	Trials (evodiamine)	Recent Studies (post-2010) (evodiamine)
48	1	18	336	1	240

Protein Interaction Comparison

Protein	Taxonomy	dehydroevodiamine (IC50)	evodiamine (IC50)
Transient receptor potential cation channel subfamily V member 1	Rattus norvegicus (Norway rat)		0.44
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)		2.1
Cholinesterase	Equus caballus (horse)		4.62

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (27.27)	18.2507
2000's	5 (45.45)	29.6817
2010's	3 (27.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, CF; Lee, TF; Tsai, TH; Wang, LC	1
Chen, CF; Chiou, WF; Liao, JF	1
Chen, CF; Chiou, WF; Liao, JF; Shum, AY; Sung, YJ	1
Chen, CF; Chen, TL; Guengerich, FP; Jan, WC; Lin, LC; Ueng, YF	1
Chen, CF; Chen, KT; Ko, HC; Ueng, YF; Wang, JJ	1
Chen, CF; Chen, CM; Chen, KT; Ko, HC; Su, JP; Wang, GJ	1
Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH	1
Teng, J; Wang, Y; Xu, W; Yang, XW	1
Hu, CQ; Li, F; Yang, XW	1
Bisson, WH; Gonzalez, FJ; Krausz, KW; Sun, D; Xie, C; Yagai, T; Yan, T; Yang, X; Zhang, L; Zhang, Y; Zheng, Y	1
Li, JJ; Tian, KM; Xu, SW	1

Reviews

1 review(s) available for dehydroevodiamine and evodiamine

Article	Year
Rutaecarpine: A promising cardiovascular protective alkaloid from Evodia rutaecarpa (Wu Zhu Yu). Pharmacological research, 2019, Volume: 141 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Evodia; Humans; Hypolipidemic Agents; Indole Alkaloids; Platelet Aggregation Inhibitors; Quinazolines; Vasodilator Agents	2019

Other Studies

10 other study(ies) available for dehydroevodiamine and evodiamine

Article	Year
Thermoregulatory effects of alkaloids isolated from Wu-chu-yu in afebrile and febrile rats. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2 Topics: Alkaloids; Animals; Body Temperature Regulation; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fever; Lipopolysaccharides; Oxygen Consumption; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Salmonella typhi	1995
Comparative study of the vasodilatory effects of three quinazoline alkaloids isolated from Evodia rutaecarpa. Journal of natural products, 1996, Volume: 59, Issue:4 Topics: Alkaloids; Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Enzyme Inhibitors; In Vitro Techniques; Indole Alkaloids; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Vasodilator Agents	1996
Inhibitory effect of dehydroevodiamine and evodiamine on nitric oxide production in cultured murine macrophages. Journal of natural products, 1997, Volume: 60, Issue:7 Topics: Alkaloids; Animals; Cells, Cultured; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Plant Extracts; Quinazolines	1997
The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:3 Topics: Alkaloids; Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Indole Alkaloids; Kinetics; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxidoreductases; Plant Extracts; Quinazolines; Structure-Activity Relationship; Substrate Specificity; Theophylline	2002
Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice. Life sciences, 2002, Aug-02, Volume: 71, Issue:11 Topics: Alkaloids; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drugs, Chinese Herbal; Glucuronosyltransferase; Glutathione Transferase; Humans; Indole Alkaloids; Liver; Male; Methanol; Mice; Mice, Inbred C57BL; Oxazines; Plant Extracts; Plants, Medicinal; Quinazolines; Rutaceae	2002
Chemical and biological comparisons on Evodia with two related species of different locations and conditions. Journal of ethnopharmacology, 2006, Nov-24, Volume: 108, Issue:2 Topics: Alkaloids; Animals; Aorta; China; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Evodia; Female; Fruit; In Vitro Techniques; Indole Alkaloids; Male; Methanol; Molecular Structure; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Plant Extracts; Quinazolines; Rats; Rats, Sprague-Dawley; Species Specificity; Synephrine; Taiwan	2006
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells. European journal of pharmacology, 2007, Jan-26, Volume: 555, Issue:2-3 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate	2007
The permeability and the efflux of alkaloids of the Evodiae fructus in the Caco-2 model. Phytotherapy research : PTR, 2009, Volume: 23, Issue:1 Topics: Alkaloids; Biological Transport, Active; Caco-2 Cells; Chromatography, High Pressure Liquid; Evodia; Humans; Indole Alkaloids; Intestinal Absorption; Permeability; Plant Extracts; Quinazolines	2009
Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction. Journal of Asian natural products research, 2012, Volume: 14, Issue:4 Topics: Administration, Oral; Alkaloids; Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Indole Alkaloids; Male; Molecular Structure; Quinazolines; Rats	2012
Structure-Activity Relationships of the Main Bioactive Constituents of Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:7 Topics: Alkaloids; Animals; Bile Acids and Salts; Cell Line, Tumor; Drugs, Chinese Herbal; Evodia; Genes, Reporter; Hep G2 Cells; Hepatocytes; Homeostasis; Humans; Indole Alkaloids; Liver; Male; Mice; Mice, Inbred C57BL; Quinazolines; Receptors, Aryl Hydrocarbon; RNA, Messenger; Structure-Activity Relationship; Up-Regulation	2018