dehydroepiandrosterone sulfate and pregnenolone sulfate

dehydroepiandrosterone sulfate has been researched along with pregnenolone sulfate in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (19.18)	18.7374
1990's	23 (31.51)	18.2507
2000's	23 (31.51)	29.6817
2010's	12 (16.44)	24.3611
2020's	1 (1.37)	2.80

Authors

Authors	Studies
Baulieu, EE; Corpéchot, C; Egestad, B; Morfin, R; Sjövall, J; Young, J	1
Hirato, K; Hondo, T; Saito, H; Suzuki, T; Yanaihara, T	1
Abdallah, MA; Baulieu, EE; Jo, DH; Robel, P; Young, J	1
Godfrey, BM; Petrucco, OM; Seamark, RF; Stone, BA	1
de la Torre, B; Hedman, M; Norén, S; Sjöberg, B	1
Walsh, SW	1
Kakumoto, Y; Kamiya, T; Kiryu, Y; Maruyama, T; Nakamoto, H; Ookawa, H; Suzuki, O; Yasui, T; Yasumura, K; Yokomori, H	1
Berthezene, F; Boizel, R; Bost, M; Cathiard, AM; de Peretti, E; Halimi, S; Saez, JM	1
Deppe, WM; Joubert, SM; Marivate, M; Norman, RJ	1
Capella-Pavlovsky, M; Castanier, M; Chartier, M; Daffos, F; Forestier, F; Nahoul, K; Scholler, R	1
Hemsell, PG; Korte, K; Mason, JI	1
de Peretti, E; Mappus, E	1
Carr, BR; Mason, JI; Parker, CR; Simpson, ER	1
Carette, B; Poulain, P	1
Lukkarinen, O; Ruokonen, A; Vihko, R	1
Gromadzińska, E; Lachowicz, L; Rebas, E; Zylińska, L	1
Baulieu, EE; Mahé, V; Monnet, FP; Robel, P	1
Santen, RJ; Santner, SJ	1
Bohr, I; Gniot-Szulzycka, J	1
Maurice, T; Privat, A; Roman, FJ	1
Gillies, GE; Murray, HE	1
Richardson, CM; Wakerley, JB	1
Kulkarni, SK; Reddy, DS	2
Akwa, Y; Baulieu, EE; El-Etr, M; Robel, P	1
Covey, DF; Nilsson, KR; Zorumski, CF	1
Maurice, T; Privat, A; Urani, A	1
Kaur, G; Kulkarni, SK; Reddy, DS	1
Bender, AS; Norenberg, MD	1
Fujinami, A; Kobayashi, Y; Tagawa, N; Tsuruta, H	1
Beaujean, D; Do-Rego, JL; Luu-The, V; Mensah-Nyagan, AG; Pelletier, G; Vaudry, H	1
Gromadzińska, E; Lachowicz, L; Zylińska, L	1
Covey, DF; Mennerick, S; Shen, W; Zorumski, CF; Zorumski, EC	1
Farb, DH; Gibbs, TT; Malayev, A; Park-Chung, M; Purdy, RH	1
Mathis, C; Meziane, H; Ungerer, A	1
Farr, SA; Flood, JF; Johnson, DA; Li, PK; Morley, JE	1
Cascio, C; De Leo, G; Guarneri, M; Guarneri, P; Guarneri, R; Piccoli, F; Russo, D	1
Nabeshima, T; Nakata, Y; Sasa, M; Yamada, K; Zou, LB	1
Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J	1
Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T	1
Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A	1
Barbosa, AD; Morato, GS	2
Le Moal, M; Mayo, W; Vallée, M	1
Lachowicz, A; Rebas, E	1
Fujiwara, M; Furusawa, H; Higashi, S; Maeda, Y; Matsu, T; Nakahara, H; Nanba, K; Setoguchi, T; Tanaka, E; Watanabe, R	1
Akwa, Y; Baulieu, EE; David, JP; Delacourte, A; Eychenne, B; Liere, P; Pianos, A; Sazdovitch, V; Schumacher, M; Weill-Engerer, S	1
Ortega, E; Torres, JM	1
KILLINGER, DW; SOLOMON, S	1
Bicíková, M; Hampl, R; Havlíková, H; Hill, M; Jirák, R; Rípová, D; Tallová, J	1
Baulieu, EE; Cambourg, A; Eychenne, B; Griffiths, W; Liere, P; Liu, S; Pianos, A; Schumacher, M; Sjövall, J	1
Hou, YN; Yan, CZ	1
Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Popov, P; Pouzar, V; Stárka, L; Vrbíková, J	1
George, O; Le Moal, M; Mayo, W; Vallée, M	1
Hou, YN; Wang, N; Wu, HH	1
Grube, M; Jedlitschky, G; Karner, S; Köck, K; Kroemer, HK; Reuther, S; Ritter, CA	1
Farb, DH; Gibbs, TT; Russek, SJ	1
Mameli, M; Meyer, DA; Partridge, LD; Valenzuela, CF	1
Bamber, BA; Covey, DF; Tartaglia, AL; Twede, V	1
Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M	1
Dusková, M; Hill, M; Kancheva, R; Kubátová, J; Stárka, L; Vceláková, H; Vrbíková, J; Zárubová, J	1
Elfverson, M; Johansson, T; Le Grevès, P; Nyberg, F; Zhou, Q	1
Dupré, A; Eychenne, B; Haccard, O; Jessus, C; Liere, P; Ozon, R; Pianos, A	1
Horishita, T; Okura, D; Sata, T; Sudo, Y; Ueno, S; Uezono, Y; Yanagihara, N	1
Burel, D; Do-Rego, JL; Kwon, HB; Li, JH; Luu-The, V; Pelletier, G; Seong, JY; Taragnat, C; Tillet, Y; Vaudry, H; Wang, AF	1
Akwa, Y; Alméras, M; Covey, DF; El Bitar, F; Krishnan, K; Maurice, T; Meunier, J; Villard, V	1
Dury, AY; Gonthier, R; Isabelle, M; Ke, Y; Labrie, F; Simard, JN	1
Bera, AK; Sachidanandan, D	1
Beitz, AJ; Choi, HS; Choi, SR; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Roh, DH; Yoon, SY	1
Auchus, RJ; Karashima, S; Kasa-Vubu, JZ; Lerario, AM; Nakamura, Y; Rainey, WE; Rege, J; Sasano, H; Smith, JM; White, PC	1
Bernhardt, R; Neunzig, J	1
Auchus, RJ; Nanba, AT; Peng, HM; Rainey, WE; Rege, J; Ren, J; Turcu, AF	1
Akk, G; Germann, AL; Pierce, SR; Steinbach, JH	1

Reviews

8 review(s) available for dehydroepiandrosterone sulfate and pregnenolone sulfate

Article	Year
[2 surgically treated cases of adrenocortical carcinoma producing steroid hormones without endocrinological symptoms--case report and a review of cases in the Japanese literature]. Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:1 Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Carcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Etiocholanolone; Humans; Male; Pregnenolone	1988
[Steroid modulation of GABA(A) receptors]. Postepy higieny i medycyny doswiadczalnej, 1995, Volume: 49, Issue:3 Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; GABA Modulators; Lipid Metabolism; Pregnenolone; Proteins; Receptors, GABA-A; Steroids	1995
[Models for the study of memory and neurosteroids]. Journal de la Societe de biologie, 1999, Volume: 193, Issue:3 Topics: Amnesia; Animals; Brain; Dehydroepiandrosterone Sulfate; Hippocampus; Humans; Learning; Memory; Mice; Models, Neurological; Models, Psychological; Pregnenolone; Rats	1999
Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging. Brain research. Brain research reviews, 2001, Volume: 37, Issue:1-3 Topics: Aging; Animals; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hippocampus; Humans; Learning; Memory; Pregnenolone; Rats; Reproducibility of Results	2001
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. Psychopharmacology, 2006, Volume: 186, Issue:3 Topics: Acetylcholine; Aging; Animals; Brain Stem; Dehydroepiandrosterone Sulfate; Humans; Memory; Memory Disorders; Pregnanolone; Pregnenolone; Prosencephalon; Sleep; Sleep Wake Disorders	2006
Sulfated steroids as endogenous neuromodulators. Pharmacology, biochemistry, and behavior, 2006, Volume: 84, Issue:4 Topics: Animals; Brain Chemistry; Dehydroepiandrosterone Sulfate; Humans; Models, Molecular; Neurotransmitter Agents; Pregnenolone; Receptors, Glutamate; Receptors, Neurotransmitter; Steroids; Sulfatases; Sulfates; Sulfotransferases	2006
Modulation of glutamatergic transmission by sulfated steroids: role in fetal alcohol spectrum disorder. Brain research reviews, 2008, Volume: 57, Issue:2 Topics: Animals; Brain; Dehydroepiandrosterone Sulfate; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glutamine; Humans; Neurons; Pregnancy; Pregnenolone; Receptors, N-Methyl-D-Aspartate; Steroids; Synaptic Transmission	2008
Effect of sulfonated steroids on steroidogenic cytochrome P450-dependent steroid hydroxylases. The Journal of steroid biochemistry and molecular biology, 2018, Volume: 179 Topics: Animals; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone Sulfate; Hormones; Humans; Pregnenolone; Steroid Hydroxylases; Steroids	2018

Trials

1 trial(s) available for dehydroepiandrosterone sulfate and pregnenolone sulfate

Article	Year
Secretion of steroid sulfates from human testis and their response to a single intramuscular injection of 5000 IU hCG. Journal of steroid biochemistry, 1981, Volume: 14, Issue:12 Topics: Adult; Aged; Androstenediol; Androstenediols; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Middle Aged; Pregnenolone; Testis; Testosterone; Veins	1981

Other Studies

64 other study(ies) available for dehydroepiandrosterone sulfate and pregnenolone sulfate

Article	Year
Neurosteroids: pregnenolone in human sciatic nerves. Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-01, Volume: 89, Issue:15 Topics: Adult; Aged; Aged, 80 and over; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Female; Humans; Male; Mass Spectrometry; Middle Aged; Pregnenolone; Radioimmunoassay; Sciatic Nerve	1992
Steroid sulfatase activities in human leukocytes: biochemical and clinical aspects. Endocrinologia japonica, 1991, Volume: 38, Issue:6 Topics: Arylsulfatases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrone; Female; Humans; Ichthyosis Vulgaris; Ichthyosis, X-Linked; Leukocytes; Male; Placenta; Pregnenolone; Steryl-Sulfatase; Tritium	1991
Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain. Steroids, 1989, Volume: 54, Issue:3 Topics: Animals; Brain Chemistry; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Estrus; Fatty Acids; Female; Male; Orchiectomy; Pregnenolone; Radioimmunoassay; Rats; Rats, Inbred Strains	1989
Concentrations of steroid hormones, and of prolactin, in washings of the human uterus during the menstrual cycle. Journal of reproduction and fertility, 1986, Volume: 78, Issue:1 Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gonadal Steroid Hormones; Humans; Menstrual Cycle; Pregnenolone; Prolactin; Proteins; Uterus	1986
Blood and tissue steroid levels and their interrelationship in men with pathological conditions of the reproductive organs. International journal of andrology, 1986, Volume: 9, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Arteries; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Epididymis; Genital Diseases, Male; Humans; Male; Middle Aged; Pregnenolone; Steroids; Testis; Testosterone; Vas Deferens; Veins	1986
Progesterone and estradiol production by normal and preeclamptic placentas. Obstetrics and gynecology, 1988, Volume: 71, Issue:2 Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Humans; In Vitro Techniques; Placenta; Pre-Eclampsia; Pregnancy; Pregnenolone; Progesterone	1988
Pattern of plasma levels of cortisol, dehydroepiandrosterone and pregnenolone sulphate in normal subjects and in patients with homozygous familial hypercholesterolaemia during ACTH infusion. Clinical endocrinology, 1986, Volume: 25, Issue:4 Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hyperlipoproteinemia Type II; Male; Pregnenolone	1986
Umbilical artery concentrations of androstenedione increased in early labour in the leading twin fetus. British journal of obstetrics and gynaecology, 1984, Volume: 91, Issue:8 Topics: Androstenedione; Cesarean Section; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Labor Stage, First; Labor Stage, Second; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Twins	1984
[Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates]. Pathologie-biologie, 1984, Volume: 32, Issue:8 Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Blood Specimen Collection; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Prenatal Diagnosis	1984
Steroidogenesis in dispersed cells of human fetal adrenal. The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cyanoketone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Pituitary Hormones; Pregnenolone; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes	1983
Pattern of plasma pregnenolone sulfate levels in humans from birth to adulthood. The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:3 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aging; Child; Child, Preschool; Chorionic Gonadotropin; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Fetal Blood; Humans; Infant; Infant, Newborn; Male; Metyrapone; Middle Aged; Pregnenolone	1983
Effect of prostaglandins on steroid secretion by human fetal adrenal tissue. Steroids, 1983, Volume: 41, Issue:5 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Estradiol; Female; Fetus; Humans; Hydrocortisone; In Vitro Techniques; Pregnancy; Pregnenolone; Prostaglandins E; Prostaglandins F; Radioimmunoassay	1983
Excitatory effect of dehydroepiandrosterone, its sulphate ester and pregnenolone sulphate, applied by iontophoresis and pressure, on single neurones in the septo-preoptic area of the guinea pig. Neuroscience letters, 1984, Mar-23, Volume: 45, Issue:2 Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Guinea Pigs; Membrane Potentials; Neurons; Pregnenolone; Preoptic Area; Septum Pellucidum; Synaptic Transmission	1984
Neuroactive steroids modulate in vivo the Mg2+/Ca(2+)-ATPase activity in rat cortical and cerebellar synaptosomal membranes. Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1 Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calmodulin; Cell Membrane; Cerebellum; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Pregnenolone; Rats; Rats, Wistar; Reference Values; Synaptosomes	1995
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-25, Volume: 92, Issue:9 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella	1995
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens. The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:5 Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pregnenolone; Rats; Rats, Sprague-Dawley; Sulfatases; Tamoxifen	1993
Modulation by neurosteroids of the in vivo (+)-[3H]SKF-10,047 binding to sigma 1 receptors in the mouse forebrain. Journal of neuroscience research, 1996, Dec-15, Volume: 46, Issue:6 Topics: Animals; Antipsychotic Agents; Binding, Competitive; Cerebral Cortex; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Gonadal Steroid Hormones; Hippocampus; Male; Mice; Phenazocine; Pregnancy; Pregnenolone; Progesterone; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, sigma; Tritium	1996
Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures. Journal of neuroendocrinology, 1997, Volume: 9, Issue:4 Topics: Animals; Bicuculline; Cells, Cultured; Dehydroepiandrosterone Sulfate; Dopamine; Drug Synergism; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Pregnanolone; Pregnenolone; Rats; Somatostatin	1997
The neurosteroid pregnenolone sulphate enhances NMDA-induced phasic firing of vasopressin neurones in the rat supraoptic nucleus. Neuroscience letters, 1997, Apr-25, Volume: 226, Issue:2 Topics: Animals; Dehydroepiandrosterone Sulfate; Drug Synergism; Evoked Potentials; Female; Hypothalamus; In Vitro Techniques; N-Methylaspartate; Neurons; Picrotoxin; Pregnenolone; Rats; Rats, Wistar; Supraoptic Nucleus; Time Factors; Vasopressins	1997
The effects of neurosteroids on acquisition and retention of a modified passive-avoidance learning task in mice. Brain research, 1998, Apr-27, Volume: 791, Issue:1-2 Topics: Animals; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dopamine Antagonists; Haloperidol; Male; Mice; Pregnenolone; Receptors, sigma; Reproducibility of Results; Retention, Psychology	1998
Opposing effects of different steroid sulfates on GABAA receptor-mediated chloride uptake. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: Animals; Biological Transport; Cerebral Cortex; Chlorides; Dehydroepiandrosterone Sulfate; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; In Vitro Techniques; Ionophores; Male; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes	1998
Neurosteroid analogues. 6. The synthesis and GABAA receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate, and (3alpha,5beta)-3-hydroxypregnan-20-one sulfate. Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14 Topics: Animals; Cells, Cultured; Dehydroepiandrosterone Sulfate; GABA Modulators; Hippocampus; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Stereoisomerism	1998
The modulation by neurosteroids of the scopolamine-induced learning impairment in mice involves an interaction with sigma1 (sigma1) receptors. Brain research, 1998, Jul-13, Volume: 799, Issue:1 Topics: Animals; Anisoles; Dehydroepiandrosterone Sulfate; Learning Disabilities; Male; Maze Learning; Mice; Muscarinic Antagonists; Pregnenolone; Progesterone; Propylamines; Receptors, sigma; Scopolamine; Swimming	1998
Possible role of nitric oxide in the nootropic and antiamnesic effects of neurosteroids on aging- and dizocilpine-induced learning impairment. Brain research, 1998, Jul-20, Volume: 799, Issue:2 Topics: Aging; Amnesia; Animals; Avoidance Learning; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Enzyme Inhibitors; Learning Disabilities; Male; Maze Learning; Memory; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nootropic Agents; Pregnenolone	1998
Sigma (sigma1) receptor mediated anti-depressant-like effects of neurosteroids in the Porsolt forced swim test. Neuroreport, 1998, Sep-14, Volume: 9, Issue:13 Topics: Animals; Anisoles; Antidepressive Agents; Behavior, Animal; Dehydroepiandrosterone Sulfate; Female; Hypokinesia; Immobilization; Injections, Intraperitoneal; Injections, Subcutaneous; Ligands; Male; Mice; Mice, Inbred Strains; Pregnenolone; Progesterone; Propylamines; Rats; Rats, Wistar; Receptors, sigma; Stress, Physiological; Swimming; Time Factors	1998
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes. Journal of neuroscience research, 1998, Dec-01, Volume: 54, Issue:5 Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation	1998
Prevention of co-elution of steroid sulfates with serum proteins from pre-column in column-switching HPLC system. Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:11 Topics: Blood Proteins; Chromatography, High Pressure Liquid; Dehydroepiandrosterone Sulfate; Estriol; Humans; Pregnenolone; Quaternary Ammonium Compounds	1998
Immunocytochemical localization and biological activity of hydroxysteroid sulfotransferase in the frog brain. Journal of neurochemistry, 1999, Volume: 72, Issue:2 Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dehydroepiandrosterone Sulfate; Immunohistochemistry; Male; Phosphoadenosine Phosphosulfate; Pregnenolone; Rabbits; Rana ridibunda; Sulfotransferases; Sulfur Radioisotopes; Tritium	1999
Short-time effects of neuroactive steroids on rat cortical Ca2+-ATPase activity. Biochimica et biophysica acta, 1999, Feb-25, Volume: 1437, Issue:2 Topics: Animals; Brain; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Dehydroepiandrosterone Sulfate; Enzyme Activation; Estradiol; Pregnenolone; Rats; Rats, Wistar; Synaptosomes; Testosterone; Up-Regulation	1999
Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors. Neuropharmacology, 1999, Volume: 38, Issue:2 Topics: Animals; Chloride Channels; Dehydroepiandrosterone Sulfate; Female; gamma-Aminobutyric Acid; Macromolecular Substances; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Picrotoxin; Pregnenolone; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis	1999
Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain research, 1999, May-29, Volume: 830, Issue:1 Topics: Animals; Cells, Cultured; Chick Embryo; Dehydroepiandrosterone Sulfate; GABA Modulators; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Steroids; Sulfuric Acid Esters; Xenopus laevis	1999
Peripheral steroid sulfatase inhibition potentiates improvement of memory retention for hippocampally administered dehydroepiandrosterone sulfate but not pregnenolone sulfate. Psychoneuroendocrinology, 1999, Volume: 24, Issue:8 Topics: Animals; Arylsulfatases; Avoidance Learning; Brain Mapping; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrone; Hippocampus; Injections; Male; Maze Learning; Mice; Pregnenolone; Retention, Psychology; Steryl-Sulfatase	1999
Pregnenolone sulfate, a naturally occurring excitotoxin involved in delayed retinal cell death. Journal of neurochemistry, 2000, Volume: 74, Issue:6 Topics: Adjuvants, Immunologic; Animals; Apoptosis; Cycloheximide; Dehydroepiandrosterone Sulfate; DNA Fragmentation; Estradiol; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Neurotoxins; Pregnenolone; Progesterone; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Retina; Superoxide Dismutase; Superoxides; Thiobarbituric Acid Reactive Substances	2000
Effects of sigma(1) receptor agonist SA4503 and neuroactive steroids on performance in a radial arm maze task in rats. Neuropharmacology, 2000, Jul-10, Volume: 39, Issue:9 Topics: Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory; Nootropic Agents; Piperazines; Pregnenolone; Progesterone; Propylamines; Psychomotor Performance; Rats; Rats, Wistar; Receptors, sigma; Steroids; Time Factors	2000
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol. Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:2 Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids	2000
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. Endocrine journal, 2001, Volume: 48, Issue:3 Topics: Adult; Androstenediol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Pregnenolone; Sex Characteristics; Sex Hormone-Binding Globulin; Thyroxine	2001
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8 Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine	2001
Influence of neurosteroids on the development of rapid tolerance to ethanol in mice. European journal of pharmacology, 2001, Nov-16, Volume: 431, Issue:2 Topics: Animals; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; Drug Interactions; Drug Tolerance; Ethanol; Male; Mice; Motor Activity; Muscimol; Pregnenolone; Steroids	2001
Gender differences in steroid modulation of angiotensin II-induced protein kinase C activity in anterior pituitary of the rat. Biochemical and biophysical research communications, 2002, May-31, Volume: 294, Issue:1 Topics: Angiotensin II; Animals; Dehydroepiandrosterone Sulfate; Estradiol; Female; Male; Ovariectomy; Phosphorylation; Pituitary Gland, Anterior; Pregnenolone; Progesterone; Protein Kinase C; Rats; Rats, Wistar; Sex Factors; Synapsins	2002
Pregnenolone sulfate, dehydroepiandrosterone sulfate and allotetrahydrodeoxycorticosterone affect rapid tolerance to the hypothermic effect of ethanol. Brain research bulletin, 2002, Volume: 58, Issue:1 Topics: Alcoholism; Animals; Body Temperature; Central Nervous System Depressants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; Mice; Pregnenolone	2002
Accumulation of 4- and 5-ene steroid sulfates in human breast cyst fluids. The Journal of steroid biochemistry and molecular biology, 2002, Volume: 81, Issue:3 Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Middle Aged; Pregnenolone	2002
Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amygdala; Amyloid beta-Peptides; Brain Chemistry; Cerebellum; Corpus Striatum; Dehydroepiandrosterone Sulfate; Female; Frontal Lobe; Gas Chromatography-Mass Spectrometry; Hippocampus; Humans; Hypothalamus; Male; Pregnanolone; Pregnenolone; Progesterone; Protein Structure, Secondary; Steroids; tau Proteins	2002
DHEA, PREG and their sulphate derivatives on plasma and brain after CRH and ACTH administration. Neurochemical research, 2003, Volume: 28, Issue:8 Topics: Adrenocorticotropic Hormone; Animals; Blood; Brain; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Male; Pregnenolone; Rats; Rats, Wistar	2003
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND. The Journal of clinical endocrinology and metabolism, 1965, Volume: 25 Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Crystallization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Metabolism; Pregnanediol; Pregnanetriol; Pregnenes; Pregnenolone; Sulfates; Tritium	1965
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia. Clinical chemistry and laboratory medicine, 2004, Volume: 42, Issue:5 Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds	2004
Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain. Journal of lipid research, 2004, Volume: 45, Issue:12 Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gas Chromatography-Mass Spectrometry; Male; Pregnenolone; Rats; Rats, Sprague-Dawley	2004
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain. Acta pharmacologica Sinica, 2004, Volume: 25, Issue:10 Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Male; Morphine Dependence; Pregnenolone; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2004
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction. Steroids, 2005, Volume: 70, Issue:8 Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors	2005
[Effects of morphine dependence on the levels of neurosteroids in rat brain]. Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11 Topics: Amygdala; Animals; Brain; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hypothalamus; Male; Morphine Dependence; Nucleus Accumbens; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley	2005
Modification of OATP2B1-mediated transport by steroid hormones. Molecular pharmacology, 2006, Volume: 70, Issue:5 Topics: Animals; Biological Transport; Dehydroepiandrosterone Sulfate; Dogs; Estrone; Gene Expression; Humans; Isotope Labeling; Kinetics; Mifepristone; Organic Anion Transporters; Pregnenolone; Progesterone; Steroids; Testosterone	2006
The neurosteroids dehydroepiandrosterone sulfate and pregnenolone sulfate inhibit the UNC-49 GABA receptor through a common set of residues. Molecular pharmacology, 2007, Volume: 72, Issue:5 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Caenorhabditis elegans Proteins; Cells, Cultured; Dehydroepiandrosterone Sulfate; GABA Antagonists; GABA-A Receptor Antagonists; Molecular Sequence Data; Mutation; Oocytes; Pregnenolone; Receptors, GABA-A; Xenopus	2007
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells. Journal of neuroscience research, 2008, May-01, Volume: 86, Issue:6 Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids	2008
Sulphates of 3beta-hydroxy-5-ene steroids in women with epilepsy. Prague medical report, 2010, Volume: 111, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Dehydroepiandrosterone Sulfate; Epilepsy; Female; Follicular Phase; Humans; Luteal Phase; Middle Aged; Pregnenolone; Young Adult	2010
Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors. Neuropharmacology, 2011, Volume: 61, Issue:7 Topics: Allosteric Regulation; Anabolic Agents; Androgens; Animals; Dehydroepiandrosterone Sulfate; Frontal Lobe; Kinetics; Male; Nandrolone; Nandrolone Decanoate; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor	2011
Naturally occurring steroids in Xenopus oocyte during meiotic maturation. Unexpected presence and role of steroid sulfates. Molecular and cellular endocrinology, 2012, Oct-15, Volume: 362, Issue:1-2 Topics: Animals; Dehydroepiandrosterone Sulfate; Female; Gonadal Hormones; Luteinizing Hormone; Meiosis; Oocytes; Ovary; Ovulation; Pregnenolone; Steryl-Sulfatase; Sulfonic Acids; Xenopus laevis	2012
Inhibition by pregnenolone sulphate, a metabolite of the neurosteroid pregnenolone, of voltage-gated sodium channels expressed in Xenopus oocytes. Journal of pharmacological sciences, 2012, Volume: 120, Issue:1 Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; NAV1.2 Voltage-Gated Sodium Channel; Oocytes; Pregnenolone; Sodium Channel Blockers; Xenopus laevis	2012
Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology, 2013, Volume: 154, Issue:6 Topics: Amino Acid Sequence; Animals; Cell Line; Dehydroepiandrosterone Sulfate; Diencephalon; Gene Expression Profiling; Gonadotropin-Releasing Hormone; Hypothalamus; In Situ Hybridization; Male; Microscopy, Confocal; Molecular Sequence Data; Neurons; Pituitary Gland; Pregnenolone; Protein Isoforms; Ranidae; Receptors, LHRH; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sulfotransferases	2013
Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ₂₅₋₃₅ peptide-induced toxicity in vitro and in vivo in mice. Psychopharmacology, 2014, Volume: 231, Issue:17 Topics: Amyloid beta-Peptides; Animals; Avoidance Learning; Behavior, Animal; Cell Line, Tumor; Cell Survival; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Mice; Neurites; Neuroprotective Agents; Peptide Fragments; Pregnenolone; Rats	2014
Validated LC-MS/MS simultaneous assay of five sex steroid/neurosteroid-related sulfates in human serum. The Journal of steroid biochemistry and molecular biology, 2015, Volume: 149 Topics: Androsterone; Chromatography, Liquid; Dehydroepiandrosterone Sulfate; Estrone; Humans; Limit of Detection; Pregnanolone; Pregnenolone; Reproducibility of Results; Tandem Mass Spectrometry	2015
Inhibition of the GABAA Receptor by Sulfated Neurosteroids: A Mechanistic Comparison Study between Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate. Journal of molecular neuroscience : MN, 2015, Volume: 56, Issue:4 Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Dehydroepiandrosterone Sulfate; GABA-A Receptor Antagonists; HEK293 Cells; Humans; Molecular Sequence Data; Pregnenolone; Protein Binding; Receptors, GABA-A	2015
Peripheral neurosteroids enhance P2X receptor-induced mechanical allodynia via a sigma-1 receptor-mediated mechanism. Brain research bulletin, 2016, Volume: 121 Topics: Adenosine Triphosphate; Animals; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylenediamines; Hyperalgesia; Male; Pain Measurement; Pregnenolone; Purinergic P2X Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Receptors, sigma; Time Factors	2016
Age-dependent Increases in Adrenal Cytochrome b5 and Serum 5-Androstenediol-3-sulfate. The Journal of clinical endocrinology and metabolism, 2016, Volume: 101, Issue:12 Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adult; Age Factors; Androstenediol; Cell Culture Techniques; Child; Child, Preschool; Cytochromes b5; Dehydroepiandrosterone Sulfate; Female; Human Development; Humans; Infant; Male; Pregnenolone; Progesterone Reductase; Young Adult	2016
Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal In Vivo and In Vitro. The Journal of clinical endocrinology and metabolism, 2018, 01-01, Volume: 103, Issue:1 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Case-Control Studies; Cells, Cultured; Dehydroepiandrosterone Sulfate; Female; Follow-Up Studies; Humans; Hyperaldosteronism; Male; Middle Aged; Pregnenolone; Prognosis	2018
The Sulfated Steroids Pregnenolone Sulfate and Dehydroepiandrosterone Sulfate Inhibit the Molecular pharmacology, 2022, Volume: 101, Issue:2 Topics: Animals; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; GABA Antagonists; Humans; Neurosteroids; Pregnenolone; Protein Stability; Receptors, GABA-A; Xenopus laevis	2022