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dehydroepiandrosterone sulfate and pregnanolone

dehydroepiandrosterone sulfate has been researched along with pregnanolone in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (18.75)18.2507
2000's31 (64.58)29.6817
2010's8 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baulieu, EE; Mahé, V; Monnet, FP; Robel, P1
Gillies, GE; Murray, HE1
Akwa, Y; Baulieu, EE; El-Etr, M; Robel, P1
Covey, DF; Nilsson, KR; Zorumski, CF1
Kulkarni, SK; Reddy, DS1
Bosboom, AM; Burrello, N; Calogero, AE; D'Agata, R; Ferrara, E; Palumbo, G; Palumbo, MA; Petraglia, F1
Bender, AS; Norenberg, MD1
Farb, DH; Gibbs, TT; Malayev, A; Park-Chung, M; Purdy, RH1
Baumann, N; Eychenne, B; Lachapelle, F; Le Goascogne, C; Robel, P; Tonon, MC1
Akwa, Y; Britton, KT; Koob, GF; Purdy, RH1
Gilmore, JH; Jarskog, LF; Lauder, JM; Lieberman, JA; Marx, CE; Morrow, AL1
Barbaccia, ML; Foddi, C; Ghezzi, P; Mennini, T; Sacco, S; Santo, ED1
Bidziński, A; Członkowska, AI; Krzaścik, P; Płaźnik, A; Siemiatkowski, M; Sienkiewicz-Jarosz, H; Szyndler, J1
Jaako, K; Kaasik, A; Kalda, A; Zharkovsky, A1
Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A1
Bicíková, M; Hill, M; Stárka, L; Tallová, J; Vrbíková, J1
Dillon, GH; Huang, RQ1
Akwa, Y; Baulieu, EE; David, JP; Delacourte, A; Eychenne, B; Liere, P; Pianos, A; Sazdovitch, V; Schumacher, M; Weill-Engerer, S1
Borgioli, G; Casarosa, E; di Bono, I; Gambacciani, M; Genazzani, AD; Genazzani, AR; Lombardi, I; Luisi, M; Palumbo, M1
Galderisi, S; Maj, M; Monteleone, P; Mucci, A; Piegari, G; Sorrentino, D1
Moenter, SM; Sullivan, SD1
Colurcio, B; De Filippis, G; Genazzani, AR; Luisi, M; Maj, M; Monteleone, P1
Alexaki, VI; Castanas, E; Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Margioris, AN; Tsatsanis, C1
Bernardi, F; Casarosa, E; Genazzani, AR; Liut, M; Lombardi, I; Luisi, S; Monteleone, P; Palumbo, M; Petraglia, F; Quirici, B1
Battastini, AM; Pochmann, D; Rücker, B; Sarkis, JJ1
Bernardi, F; Casarosa, E; Genazzani, AD; Genazzani, AR; Luisi, S; Palumbo, M; Pluchino, N1
Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Margioris, AN; Stournaras, C; Tsatsanis, C; Vardouli, L1
Johansson, T; Le Grevès, P1
Bernasconi, S; Casarosa, E; Iughetti, L; Luisi, S; Petraglia, F; Predieri, B1
Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Popov, P; Pouzar, V; Stárka, L; Vrbíková, J1
Biggio, G; Concas, A; Contu, R; Lello, S; Marotto, MF; Melis, GB; Orrù, MM; Paoletti, AM; Romagnino, S; Zedda, P1
George, O; Le Moal, M; Mayo, W; Vallée, M1
Hou, YN; Wang, N; Wu, HH1
Greer, JJ; Ren, J1
Balli, F; Bernasconi, S; Casarosa, E; De Simone, M; Iughetti, L; Luisi, S; Petraglia, F; Predieri, B; Rossi, M1
Chopde, CT; Hirani, K; Kokare, DM; Sharma, AN; Ugale, RR1
Bishnoi, M; Chopra, K; Kulkarni, SK1
Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M1
Budziszewska, B; Jantas, D; Lason, W; Leskiewicz, M1
J M, V; N S, J; P V, D; S N, U1
Casarosa, E; Chierchia, E; Genazzani, AD; Genazzani, AR; Luisi, M; Rattighieri, E; Santagni, S1
Elfverson, M; Johansson, T; Le Grevès, P; Nyberg, F; Zhou, Q1
Casarosa, E; Genazzani, AD; Genazzani, AR; Petignat, P; Pluchino, N; Santoro, A; Wenger, JM1
Dury, AY; Gonthier, R; Isabelle, M; Ke, Y; Labrie, F; Simard, JN1
Allega, OR; Coote, M; Costescu, D; Frey, BN; Hall, GBC; Minuzzi, L; Smith, M; Syan, SK1
Cai, H; Dougherty, GG; Haas, GL; Keshavan, M; Montrose, DM; Reddy, RD; Yao, JK; Zhou, X1
Anderson, GM; Gregor, K; Hamouda, M; King, MW; Nillni, YI; Pineles, SL; Pinna, G; Rasmusson, AM; Scioli-Salter, E; Valovski, I1
Froger, N1

Reviews

3 review(s) available for dehydroepiandrosterone sulfate and pregnanolone

ArticleYear
Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes.
    Psychopharmacology, 2006, Volume: 186, Issue:3

    Topics: Acetylcholine; Aging; Animals; Brain Stem; Dehydroepiandrosterone Sulfate; Humans; Memory; Memory Disorders; Pregnanolone; Pregnenolone; Prosencephalon; Sleep; Sleep Wake Disorders

2006
Advances in neurosteroids: role in clinical practice.
    Climacteric : the journal of the International Menopause Society, 2013, Volume: 16 Suppl 1

    Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Menopause; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Premenstrual Syndrome; Progesterone; Reproduction

2013
[New therapeutic avenues for neurosteroids in psychiatric diseases].
    Biologie aujourd'hui, 2019, Volume: 213, Issue:3-4

    Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Drugs, Investigational; Humans; Mental Disorders; Neuronal Plasticity; Neurosteroids; Pregnanolone; Psychiatry; Signal Transduction; Therapies, Investigational

2019

Trials

2 trial(s) available for dehydroepiandrosterone sulfate and pregnanolone

ArticleYear
Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity.
    Psychoneuroendocrinology, 2006, Volume: 31, Issue:4

    Topics: Adult; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Female; Follow-Up Studies; GABA-A Receptor Agonists; Humans; Hydrocortisone; Menstrual Cycle; Neuropsychological Tests; Pregnancy; Pregnanes; Pregnanolone; Progesterone; Prospective Studies; Psychiatric Status Rating Scales; Psychometrics; Receptors, GABA-A; Reference Values; Stress, Psychological

2006
Metformin administration restores allopregnanolone response to adrenocorticotropic hormone (ACTH) stimulation in overweight hyperinsulinemic patients with PCOS.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2010, Volume: 26, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone Sulfate; Drug Synergism; Drug Therapy, Combination; Estradiol; Female; Humans; Hyperinsulinism; Hypoglycemic Agents; Metformin; Overweight; Polycystic Ovary Syndrome; Pregnanolone; Young Adult

2010

Other Studies

43 other study(ies) available for dehydroepiandrosterone sulfate and pregnanolone

ArticleYear
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Apr-25, Volume: 92, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella

1995
Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures.
    Journal of neuroendocrinology, 1997, Volume: 9, Issue:4

    Topics: Animals; Bicuculline; Cells, Cultured; Dehydroepiandrosterone Sulfate; Dopamine; Drug Synergism; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Pregnanolone; Pregnenolone; Rats; Somatostatin

1997
Opposing effects of different steroid sulfates on GABAA receptor-mediated chloride uptake.
    Brain research, 1998, Apr-20, Volume: 790, Issue:1-2

    Topics: Animals; Biological Transport; Cerebral Cortex; Chlorides; Dehydroepiandrosterone Sulfate; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; In Vitro Techniques; Ionophores; Male; Muscimol; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes

1998
Neurosteroid analogues. 6. The synthesis and GABAA receptor pharmacology of enantiomers of dehydroepiandrosterone sulfate, pregnenolone sulfate, and (3alpha,5beta)-3-hydroxypregnan-20-one sulfate.
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: Animals; Cells, Cultured; Dehydroepiandrosterone Sulfate; GABA Modulators; Hippocampus; Neurons; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Stereoisomerism

1998
The role of GABA-A and mitochondrial diazepam-binding inhibitor receptors on the effects of neurosteroids on food intake in mice.
    Psychopharmacology, 1998, Volume: 137, Issue:4

    Topics: Animals; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Eating; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Mitochondria; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate

1998
The neuroactive steroid allopregnanolone suppresses hypothalamic gonadotropin-releasing hormone release through a mechanism mediated by the gamma-aminobutyric acidA receptor.
    The Journal of endocrinology, 1998, Volume: 158, Issue:1

    Topics: Animals; Dehydroepiandrosterone Sulfate; Depression, Chemical; GABA Antagonists; GABA Modulators; Gonadotropin-Releasing Hormone; Hypothalamus; Isomerism; Male; Organ Culture Techniques; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1998
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
    Journal of neuroscience research, 1998, Dec-01, Volume: 54, Issue:5

    Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation

1998
Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites.
    Brain research, 1999, May-29, Volume: 830, Issue:1

    Topics: Animals; Cells, Cultured; Chick Embryo; Dehydroepiandrosterone Sulfate; GABA Modulators; Patch-Clamp Techniques; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Steroids; Sulfuric Acid Esters; Xenopus laevis

1999
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.
    Glia, 2000, Jan-01, Volume: 29, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Adrenal Cortex; Animals; Brain; Brain Chemistry; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Demyelinating Diseases; Diazepam Binding Inhibitor; Immunohistochemistry; Leydig Cells; Male; Mice; Mice, Inbred Strains; Mice, Jimpy; Mice, Neurologic Mutants; Neuropeptides; Organ Specificity; Peptide Fragments; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Up-Regulation

2000
The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat.
    Behavioural brain research, 1999, Volume: 106, Issue:1-2

    Topics: Amygdala; Animals; Anti-Anxiety Agents; Conflict, Psychological; Dehydroepiandrosterone Sulfate; Female; Injections; Injections, Intraventricular; Ovariectomy; Pregnanolone; Pregnenolone; Punishment; Rats; Rats, Wistar

1999
Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia.
    Brain research, 2000, Jul-14, Volume: 871, Issue:1

    Topics: Animals; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Embryo, Mammalian; Estradiol; Gestational Age; Microtubule-Associated Proteins; Neurons; Pregnanolone; Rats; Rats, Sprague-Dawley

2000
Neurosteroid levels are increased in vivo after LPS treatment and negatively regulate LPS-induced TNF production.
    European cytokine network, 2000, Volume: 11, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Dehydroepiandrosterone Sulfate; Hippocampus; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Pregnanolone; Pregnenolone; Progesterone; Tumor Necrosis Factor-alpha

2000
The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:2

    Topics: Animals; Bicuculline; Central Nervous System Depressants; Convulsants; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; N-Methylaspartate; Picrotoxin; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Reflex; Seizures; Sleep; Steroids

2000
Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture.
    Neuroscience, 2001, Volume: 102, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Cell Count; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Colchicine; Dehydroepiandrosterone Sulfate; Dizocilpine Maleate; GABA Modulators; Glucose; Glutamic Acid; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Pentobarbital; Picrotoxin; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism

2001
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
    Clinical chemistry and laboratory medicine, 2001, Volume: 39, Issue:8

    Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine

2001
Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2002, Volume: 110, Issue:2

    Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Blood Glucose; Body Constitution; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Metformin; Polycystic Ovary Syndrome; Pregnanolone; Steroids

2002
Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice.
    Journal of neurophysiology, 2002, Volume: 88, Issue:4

    Topics: Anesthetics; Animals; Animals, Newborn; Anticonvulsants; Carbolines; Convulsants; Dehydroepiandrosterone Sulfate; Diazepam; Diuretics; Female; Furosemide; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypothalamus; Male; Membrane Potentials; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Pregnanolone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles; Zinc; Zolpidem

2002
Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amygdala; Amyloid beta-Peptides; Brain Chemistry; Cerebellum; Corpus Striatum; Dehydroepiandrosterone Sulfate; Female; Frontal Lobe; Gas Chromatography-Mass Spectrometry; Hippocampus; Humans; Hypothalamus; Male; Pregnanolone; Pregnenolone; Progesterone; Protein Structure, Secondary; Steroids; tau Proteins

2002
Adrenal function under long-term raloxifene administration.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2003, Volume: 17, Issue:2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; beta-Endorphin; Body Mass Index; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Estrone; Female; Glucocorticoids; Humans; Hydrocortisone; Hypothalamus; Middle Aged; Pituitary Gland; Postmenopause; Pregnanolone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2003
Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroids.
    Biological psychiatry, 2003, May-15, Volume: 53, Issue:10

    Topics: Adolescent; Adult; Body Mass Index; Case-Control Studies; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Feeding and Eating Disorders; Female; Humans; Hydrocortisone; Learning; Neuropsychological Tests; Pregnanolone; Regression Analysis; Steroids

2003
Neurosteroids alter gamma-aminobutyric acid postsynaptic currents in gonadotropin-releasing hormone neurons: a possible mechanism for direct steroidal control.
    Endocrinology, 2003, Volume: 144, Issue:10

    Topics: Animals; Dehydroepiandrosterone Sulfate; Electric Conductivity; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; In Vitro Techniques; Mice; Neurons; Patch-Clamp Techniques; Pregnanolone; Pressure; Synapses; Synaptic Transmission

2003
Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects.
    The International journal of eating disorders, 2003, Volume: 34, Issue:4

    Topics: Adult; Bulimia; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Multivariate Analysis; Obesity; Pregnanolone

2003
Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, May-25, Volume: 101, Issue:21

    Topics: Adrenal Medulla; Animals; Apoptosis; bcl-X Protein; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estrogens; Isoenzymes; NF-kappa B; PC12 Cells; Phosphorylation; Pregnanolone; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, sigma; Sigma-1 Receptor

2004
Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 18, Issue:2

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Female; Follicular Phase; Humans; Hydrocortisone; Luteal Phase; Pregnanolone; Pregnenolone; Premenstrual Syndrome; Progesterone; Testosterone

2004
Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum.
    Thrombosis research, 2004, Volume: 114, Issue:4

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apyrase; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gonadal Steroid Hormones; Hormone Replacement Therapy; Hydrolysis; Ovariectomy; Pregnanolone; Rats; Rats, Wistar

2004
Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin.
    Fertility and sterility, 2005, Volume: 83 Suppl 1

    Topics: Adjuvants, Immunologic; Adrenal Glands; Animals; beta-Endorphin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Hippocampus; Hypothalamo-Hypophyseal System; Hypothalamus; Ovariectomy; Pituitary Gland, Anterior; Pituitary-Adrenal System; Pregnanolone; Rats; Rats, Wistar

2005
Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization.
    Endocrinology, 2005, Volume: 146, Issue:8

    Topics: Actins; Animals; Catecholamines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Primers; Enzyme Induction; Nicotine; PC12 Cells; Pregnanolone; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Zona Reticularis

2005
The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:1-3

    Topics: Animals; Cell Membrane; Dehydroepiandrosterone Sulfate; Frontal Lobe; Kinetics; Piperidines; Pregnanolone; Rats; Receptors, N-Methyl-D-Aspartate

2005
Low serum allopregnanolone levels in girls with precocious pubarche.
    Steroids, 2005, Volume: 70, Issue:10

    Topics: Adrenocorticotropic Hormone; Anesthetics; Child; Dehydroepiandrosterone Sulfate; Female; Gonadotropin-Releasing Hormone; Humans; Pregnanolone; Puberty; Puberty, Precocious

2005
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
    Steroids, 2005, Volume: 70, Issue:8

    Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors

2005
[Effects of morphine dependence on the levels of neurosteroids in rat brain].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:11

    Topics: Amygdala; Animals; Brain; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hypothalamus; Male; Morphine Dependence; Nucleus Accumbens; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley

2005
Neurosteroid modulation of respiratory rhythm in rats during the perinatal period.
    The Journal of physiology, 2006, Jul-15, Volume: 574, Issue:Pt 2

    Topics: Action Potentials; Animals; Animals, Newborn; Central Nervous System; Dehydroepiandrosterone Sulfate; Female; GABA Agonists; Muscimol; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Respiratory Mechanics

2006
High basal serum allopregnanolone levels in overweight girls.
    International journal of obesity (2005), 2007, Volume: 31, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenocorticotropic Hormone; Child; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gonadotropins, Pituitary; Humans; Hydrocortisone; Obesity; Pregnanolone; Puberty

2007
Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats.
    European journal of pharmacology, 2007, Jul-19, Volume: 567, Issue:3

    Topics: Animals; Anxiety; Central Nervous System Depressants; Dehydroepiandrosterone Sulfate; Drug Tolerance; Enzyme Inhibitors; Ethanol; Finasteride; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome

2007
Modulatory effect of neurosteroids in haloperidol-induced vacuous chewing movements and related behaviors.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Animals; Behavior, Animal; Catalase; Corpus Striatum; Dehydroepiandrosterone Sulfate; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Haloperidol; Homovanillic Acid; Injections, Intraperitoneal; Lipid Peroxidation; Male; Mastication; Norepinephrine; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Wistar; Serotonin; Superoxide Dismutase; Superoxides

2008
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
    Journal of neuroscience research, 2008, May-01, Volume: 86, Issue:6

    Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids

2008
Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:3

    Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids

2008
Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Oct-01, Volume: 33, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Injections, Intraventricular; Male; Maze Learning; Mice; Motor Activity; Obsessive-Compulsive Disorder; Pregnanolone; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Physiological

2009
Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors.
    Neuropharmacology, 2011, Volume: 61, Issue:7

    Topics: Allosteric Regulation; Anabolic Agents; Androgens; Animals; Dehydroepiandrosterone Sulfate; Frontal Lobe; Kinetics; Male; Nandrolone; Nandrolone Decanoate; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor

2011
Validated LC-MS/MS simultaneous assay of five sex steroid/neurosteroid-related sulfates in human serum.
    The Journal of steroid biochemistry and molecular biology, 2015, Volume: 149

    Topics: Androsterone; Chromatography, Liquid; Dehydroepiandrosterone Sulfate; Estrone; Humans; Limit of Detection; Pregnanolone; Pregnenolone; Reproducibility of Results; Tandem Mass Spectrometry

2015
Influence of endogenous estradiol, progesterone, allopregnanolone, and dehydroepiandrosterone sulfate on brain resting state functional connectivity across the menstrual cycle.
    Fertility and sterility, 2017, Volume: 107, Issue:5

    Topics: Adolescent; Adult; Brain; Connectome; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gonadal Steroid Hormones; Humans; Menstrual Cycle; Middle Aged; Nerve Net; Neuronal Plasticity; Pregnanolone; Progesterone; Rest; Young Adult

2017
Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia.
    Psychoneuroendocrinology, 2018, Volume: 90

    Topics: Adult; Antipsychotic Agents; Biomarkers, Pharmacological; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Male; Metabolic Networks and Pathways; Pregnanolone; Pregnenolone; Progesterone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2018
Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD.
    Psychoneuroendocrinology, 2019, Volume: 102

    Topics: 5-alpha-Dihydroprogesterone; Adult; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depressive Disorder, Major; GABAergic Neurons; Gas Chromatography-Mass Spectrometry; Humans; Hydroxysteroid Dehydrogenases; Male; Middle Aged; Neurosteroids; Pregnanolone; Progesterone; Severity of Illness Index; Stress Disorders, Post-Traumatic

2019