Compounds > dehydroepiandrosterone sulfate
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dehydroepiandrosterone sulfate and methotrexate

dehydroepiandrosterone sulfate has been researched along with methotrexate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's12 (80.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T1
Abe, T; Adachi, H; Asano, N; Date, F; Fujiwara, K; Iinuma, K; Ito, S; Kakyo, M; Kondo, TN; Kondo, Y; Matsuno, S; Nagura, H; Nakagomi, R; Nishio, T; Nunoki, K; Ohtani, H; Okabe, M; Ono, K; Onogawa, T; Sato, E; Seki, M; Shiiba, K; Shimosegawa, T; Sugita, J; Suzuki, M; Suzuki, T; Tanemoto, M; Tokui, T; Unno, M1
Abe, T; Inui, K; Masuda, S; Saito, H; Takeuchi, A1
Cattori, V; Hagenbuch, B; Landmann, L; Meier, PJ; Meijer, DK; Stieger, B; van Montfoort, JE; Winterhalter, KH1
Folkers, G; Hagenbuch, B; Klenk, U; Meier, PJ; Pizzagalli, F; Stieger, B1
Sugimoto, Y; Sugiyama, Y; Suzuki, H; Suzuki, M1
Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M1
Bai, J; Goh, BC; Lai, L; Tan, TM; Yeo, HC1
Belinsky, MG; Chen, ZS; Guo, Y; Kotova, E; Kruh, GD1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Bijlsma, JW; Geertzen, RG; van den Brink, HR; van Wijk, MJ1
Bartoli, E; Casatta, L; Ferraccioli, G1
Belinsky, MG; Chen, ZS; Guo, Y; Hopper-Borge, E; Kruh, GD1
Hasegawa, M; Kondo, T; Kusuhara, H; Nakazawa, H; Nozaki, Y; Okano, T; Shiroyanagi, Y; Sugiyama, Y1

Reviews

2 review(s) available for dehydroepiandrosterone sulfate and methotrexate

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
ABCC10, ABCC11, and ABCC12.
    Pflugers Archiv : European journal of physiology, 2007, Volume: 453, Issue:5

    Topics: Animals; ATP-Binding Cassette Transporters; Cerumen; Dehydroepiandrosterone Sulfate; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Methotrexate; Multidrug Resistance-Associated Proteins; Neoplasms; Nucleotides, Cyclic; Substrate Specificity

2007

Other Studies

13 other study(ies) available for dehydroepiandrosterone sulfate and methotrexate

ArticleYear
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis

2001
LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers.
    Gastroenterology, 2001, Volume: 120, Issue:7

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Antimetabolites, Antineoplastic; Carrier Proteins; Gastrointestinal Neoplasms; Humans; Immunohistochemistry; Liver; Methotrexate; Molecular Sequence Data; Xenopus laevis

2001
Multispecific substrate recognition of kidney-specific organic anion transporters OAT-K1 and OAT-K2.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:1

    Topics: Animals; Carrier Proteins; Cattle; Cell Line; Cells, Cultured; Folic Acid Antagonists; Kidney; Kinetics; Membrane Proteins; Methotrexate; Multidrug Resistance-Associated Proteins; Oocytes; Organ Specificity; Organic Anion Transporters; Substrate Specificity; Transfection; Xenopus laevis

2001
Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 443, Issue:2

    Topics: Animals; Biological Transport; Female; Liver; Oocytes; Organic Anion Transporters, Sodium-Independent; Rats; Solute Carrier Organic Anion Transporter Family Member 1B3; Subcellular Fractions; Substrate Specificity; Tissue Distribution; Xenopus laevis

2001
Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:10

    Topics: Amino Acid Sequence; Animals; Brain; CHO Cells; Chromosomes, Human, Pair 12; Cloning, Molecular; Cricetinae; Diiodothyronines; Estradiol; Estrone; Female; Humans; Leydig Cells; Male; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Anion Transporters; Sequence Homology, Amino Acid; Sulfobromophthalein; Testis; Thyroxine; Triiodothyronine; Xenopus

2002
ABCG2 transports sulfated conjugates of steroids and xenobiotics.
    The Journal of biological chemistry, 2003, Jun-20, Volume: 278, Issue:25

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Humans; Kinetics; Lymphoma; Mice; Neoplasm Proteins; Recombinant Proteins; Steroids; Sulfuric Acids; Transfection; Tumor Cells, Cultured; Xenobiotics

2003
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium

2003
Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.
    The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:2

    Topics: Adenosine Triphosphate; Anions; Antimetabolites, Antineoplastic; Benzbromarone; Biological Transport; Biological Transport, Active; Bridged Bicyclo Compounds; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; Dinitrochlorobenzene; Drug Resistance; Estradiol; Glutathione; Humans; Indomethacin; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxygen; Phosphorylation; Thioguanine; Time Factors; Transfection; Verapamil

2004
Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).
    Molecular pharmacology, 2005, Volume: 67, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Dose-Response Relationship, Drug; Estradiol; Humans; Leukotriene C4; LLC-PK1 Cells; Protein Transport; Swine

2005
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Influence of corticosteroid pulse therapy on the serum levels of soluble interleukin 2 receptor, interleukin 6 and interleukin 8 in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Female; Gold; HLA-DR Antigens; Humans; Hydrocortisone; Infusions, Intravenous; Interleukin-6; Interleukin-8; Lymphocyte Subsets; Male; Methotrexate; Middle Aged; Receptors, Interleukin-2; Rheumatoid Factor; Sex Hormone-Binding Globulin; Sulfasalazine

1994
Increase of bone mineral density and anabolic variables in patients with rheumatoid arthritis resistant to methotrexate after cyclosporin A therapy.
    The Journal of rheumatology, 1996, Volume: 23, Issue:9

    Topics: Acute-Phase Proteins; Arthritis, Rheumatoid; Bone Density; C-Reactive Protein; Cyclosporine; Dehydroepiandrosterone Sulfate; Drug Resistance; Female; Humans; Insulin-Like Growth Factor I; Joints; Male; Methotrexate; Middle Aged; Osteocalcin; Retreatment

1996
Characterization of the uptake of organic anion transporter (OAT) 1 and OAT3 substrates by human kidney slices.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Biological Transport, Active; Cell Line; Dehydroepiandrosterone Sulfate; Estrone; Humans; In Vitro Techniques; Kidney; Kinetics; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; RNA, Messenger; Transfection

2007