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dehydroepiandrosterone sulfate and flutamide

dehydroepiandrosterone sulfate has been researched along with flutamide in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.90)18.7374
1990's14 (45.16)18.2507
2000's12 (38.71)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Kirschner, MA; Luthold, WW; Marcondes, JA; Minnani, SL; Samojlik, E; Wajchenberg, BL1
Torday, JS1
Belanger, A; Bergeron, V; Dupont, A; Emond, J; Giguere, M; Labrie, F; Lacoursiere, Y; Monfette, G1
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F1
Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M1
Bégin, D; Labrie, F; Luthy, IA1
Armanini, D; Castello, R; Fontanarosa, MC; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F1
Benz, R; Rossmanith, WG; Schenkel, B1
Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S1
Rabenbauer, B; Sir-Petermann, T; Wildt, L1
Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR1
Angelini, F; Barletta, D; Gargani, M; Genazzani, AD; Genazzani, AR; Lippi, F; Luisi, M; Monzani, F; Pucci, E1
Chuzel, F; Clark, AM; Saez, JM; Sanchez, P1
Bélanger, A; Flamand, M; Labrie, C; Labrie, F1
De Fusco, D; Eleftheriou, G; Falsetti, L; Rosina, B1
Diamanti-Kandarakis, E; Duleba, AJ; Mitrakou, A; Raptis, S; Tolis, G1
Cariello, PL; D'Antona, D; De Leo, V; la Marca, A; Lanzetta, D; Morgante, G1
Bayram, F; Müderris, II1
Bayram, F; Güven, M; Müderris, II1
Arora, TK; Burt, CM; Eagleson, CA; Evans, WS; Gingrich, MB; Marshall, JC; Pastor, CL1
Barker, JL; Chang, YH; Li, Bs; Ma, W; Rubinow, DR; Zhang, L; Zhao, W1
Ajossa, S; Guerriero, S; Melis, GB; Orrù, M; Paoletti, AM1
Carmina, E; Lobo, RA1
Başogul, O; Inal, M; Ispahi, C; Karanfil, C; Onoglu, A; Taner, C; Tinar, S1
Dvoráková, K; Hill, M; Stanická, S; Stárka, L; Vondra, K; Vrbíková, J1
Nakajima, A; Sekihara, H; Takahashi, H1
Aral, Y; Culha, C; Demirbas, B; Karakurt, F; Kosar, F; Sahin, I; Serter, R; Taskapan, C1
Browne, AE; Chatterjee, K; Chou, TM; Hutchison, SJ; Ko, E; Komesaroff, PA; Sudhir, K; Zellner, C1
Chang, RJ; Malcom, PJ; Mehta, RV1
Hara, N; Hoshii, T; Isahaya, E; Ishizaki, F; Nishiyama, T; Takahashi, K; Takizawa, I1

Trials

13 trial(s) available for dehydroepiandrosterone sulfate and flutamide

ArticleYear
Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: a marked improvement in response and survival.
    Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B

    Topics: Acid Phosphatase; Anilides; Bone and Bones; Bone Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Orchiectomy; Prostatic Neoplasms; Radionuclide Imaging; Testosterone

1985
Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior.
    Fertility and sterility, 1995, Volume: 64, Issue:3

    Topics: Acne Vulgaris; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Hirsutism; Humans; Leukocytes, Mononuclear; Receptors, Androgen; Testosterone

1995
Role of androgens in the regulation of the human menstrual cycle.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1994, Volume: 8, Issue:3

    Topics: Administration, Oral; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Luteinizing Hormone; Menstrual Cycle; Progesterone; Radioimmunoassay; Receptors, Androgen; Sex Hormone-Binding Globulin; Testosterone

1994
Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism.
    Fertility and sterility, 1994, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Spironolactone; Testosterone

1994
Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial.
    Fertility and sterility, 1994, Volume: 61, Issue:2

    Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Premenopause; Progesterone; Spironolactone; Testosterone

1994
Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1997, Volume: 11, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone Sulfate; Female; Finasteride; Flutamide; Hirsutism; Humans; Insulin; Luteinizing Hormone; Polycystic Ovary Syndrome; Testosterone

1997
Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Prolactin; Sex Hormone-Binding Globulin; Testosterone

1999
A prospective, randomized trial comparing flutamide (250 mg/d) and finasteride (5 mg/d) in the treatment of hirsutism.
    Fertility and sterility, 2000, Volume: 73, Issue:5

    Topics: Adult; Androgen Antagonists; Body Mass Index; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Estradiol; Female; Finasteride; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Prospective Studies; Sex Hormone-Binding Globulin

2000
Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:11

    Topics: 17-alpha-Hydroxyprogesterone; Activity Cycles; Adult; Androgen Antagonists; Body Mass Index; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Reference Values; Thyroxine

2000
The antiandrogenic effect of flutamide improves uterine perfusion in women with polycystic ovary syndrome.
    Fertility and sterility, 2002, Volume: 77, Issue:6

    Topics: Administration, Oral; Adult; Androgen Antagonists; Arteries; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Placebos; Polycystic Ovary Syndrome; Pulse; Regional Blood Flow; Ultrasonography; Uterus

2002
Treatment of hyperandrogenic alopecia in women.
    Fertility and sterility, 2003, Volume: 79, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Adult; Alopecia; Androgen Antagonists; Cyproterone Acetate; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Ethinyl Estradiol; Female; Finasteride; Flutamide; Humans; Hyperandrogenism; Italy; Liver; Testosterone

2003
Comparison of the clinical efficacy and safety of flutamide versus flutamide plus an oral contraceptive in the treatment of hirsutism.
    Gynecologic and obstetric investigation, 2002, Volume: 54, Issue:2

    Topics: Administration, Oral; Adult; Androgen Antagonists; Contraceptives, Oral; Cyproterone Acetate; Dehydroepiandrosterone Sulfate; Drug Administration Schedule; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Hirsutism; Humans; Liver Function Tests; Prolactin; Severity of Illness Index; Testosterone; Treatment Outcome

2002
Metformin versus flutamide in the treatment of metabolic consequences of non-obese young women with polycystic ovary syndrome: a randomized prospective study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Luteinizing Hormone; Metformin; Polycystic Ovary Syndrome; Prospective Studies; Testosterone

2004

Other Studies

18 other study(ies) available for dehydroepiandrosterone sulfate and flutamide

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Treatment of hirsutism in women with flutamide.
    Fertility and sterility, 1992, Volume: 57, Issue:3

    Topics: Adult; Analysis of Variance; Androstane-3,17-diol; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome

1992
Androgens delay human fetal lung maturation in vitro.
    Endocrinology, 1990, Volume: 126, Issue:6

    Topics: Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Fetal Organ Maturity; Flutamide; Humans; Lung; Phosphatidylcholines; Pulmonary Surfactants

1990
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:6

    Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms

1987
Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:5

    Topics: Anilides; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Flutamide; Gonadal Steroid Hormones; Hormones; Humans; Middle Aged; Time Factors

1988
Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro.
    Molecular and cellular endocrinology, 1988, Volume: 58, Issue:2-3

    Topics: Androgens; Androstenediol; Androstenediols; Androstenedione; Animals; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Growth; Male; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured

1988
The effect of flutamide on pulsatile gonadotrophin secretion in hyperandrogenaemic women.
    Human reproduction (Oxford, England), 1993, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Luteinizing Hormone; Sex Hormone-Binding Globulin; Testosterone

1993
Prolonged treatment of hirsutism with flutamide alone in patients affected by polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1995, Volume: 9, Issue:3

    Topics: Adult; Androgen Antagonists; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Ultrasonography

1995
Regulation by gonadotropins of the messenger ribonucleic acid for P450 side-chain cleavage, P450(17) alpha-hydroxylase/C17,20-lyase, and 3 beta-hydroxysteroid dehydrogenase in cultured pig Leydig cells.
    Biology of reproduction, 1996, Volume: 55, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Animals; Aromatase Inhibitors; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Flutamide; Gene Expression Regulation, Enzymologic; Gonadotropins; Kinetics; Leydig Cells; Luteinizing Hormone; Male; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Swine; Testosterone

1996
High bioavailability of dehydroepiandrosterone administered percutaneously in the rat.
    The Journal of endocrinology, 1996, Volume: 150 Suppl

    Topics: Administration, Cutaneous; Administration, Oral; Androgen Antagonists; Animals; Biological Availability; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Luteinizing Hormone; Male; Organ Size; Ovariectomy; Prostate; Rats; Rats, Sprague-Dawley; Uterus

1996
The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:8

    Topics: Adult; Androgen Antagonists; Androstane-3,17-diol; Androstenedione; Cholesterol; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Hyperlipidemias; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Liver Function Tests; Obesity; Polycystic Ovary Syndrome; Testosterone; Triglycerides

1998
Effects of flutamide on pituitary and adrenal responsiveness to corticotrophin releasing factor (CRF).
    Clinical endocrinology, 1998, Volume: 49, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androgen Antagonists; Androgens; Androstenedione; Area Under Curve; Corticotropin-Releasing Hormone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Hydrocortisone; Pituitary-Adrenal System; Polycystic Ovary Syndrome; Testosterone

1998
Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways.
    Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2

    Topics: Androgen Antagonists; Animals; Apoptosis; Chromones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fetal Proteins; Flutamide; Morpholines; Nerve Tissue Proteins; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen; Telencephalon

2002
Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome.
    Gynecologic and obstetric investigation, 2004, Volume: 58, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgen Antagonists; Androgens; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipids; Obesity; Polycystic Ovary Syndrome; Steroids; Testosterone

2004
Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:3

    Topics: Adult; Apoptosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flow Cytometry; Flutamide; Humans; Lymphocytes; Male; Middle Aged; Staurosporine; Tamoxifen

2004
Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:3

    Topics: Androgen Antagonists; Animals; ATP-Binding Cassette Transporters; Coronary Circulation; Coronary Vessels; Dehydroepiandrosterone Sulfate; Echocardiography, Doppler; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Female; Flutamide; Fulvestrant; Glyburide; Hemodynamics; In Vitro Techniques; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Pericardium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Sex Characteristics; Swine; Testosterone; Vasodilation

2005
The effect of androgen blockade on granulosa cell estradiol production after follicle-stimulating hormone stimulation in women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Adult; Androgen Antagonists; Androstenedione; Area Under Curve; Cohort Studies; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Prospective Studies; Recombinant Proteins; Sex Hormone-Binding Globulin; Testosterone

2006
Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer.
    Urologic oncology, 2012, Volume: 30, Issue:5

    Topics: Adrenocorticotropic Hormone; Aged; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Dehydroepiandrosterone Sulfate; Flutamide; Goserelin; Human Growth Hormone; Humans; Immunoassay; Insulin-Like Growth Factor I; Logistic Models; Luteinizing Hormone; Male; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone

2012