dehydroepiandrosterone has been researched along with pregnenolone in 878 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 588 (66.97) | 18.7374 |
| 1990's | 108 (12.30) | 18.2507 |
| 2000's | 115 (13.10) | 29.6817 |
| 2010's | 57 (6.49) | 24.3611 |
| 2020's | 10 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Good, AC; Peterson, SJ; Richards, WG | 1 |
| Good, AC; Richards, WG; So, SS | 1 |
| Platt, DE; Silverman, BD | 1 |
| Hamprecht, FA; Kubinyi, H; Mietzner, T | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Clementi, S; Cruciani, G; McLay, I; Pastor, M; Pickett, S | 1 |
| Baumann, K; Stiefl, N | 1 |
| Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H | 1 |
| Higashiura, K; Kotani, T | 1 |
| Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N | 1 |
| Norman, E; Phillips, R; Shervington, A; Shervington, LA; Smith, N; Ward, T | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Dawson, M; Fairweather, EE; Hamilton, NM; Hamilton, NS; Hitchin, JR; James, DI; Jones, SD; Jordan, AM; Lyons, AJ; Ogilvie, DJ; Small, HF; Thomson, GJ; Waddell, ID | 1 |
| Abraham, GE; Blakely, JL; Buster, JE; Chang, RJ; Hobel, CJ; Marshall, JR; Okada, DM | 1 |
| Schindler, AE | 2 |
| Iwamori, M; Kishimoto, Y; Moser, HW | 1 |
| Bedrak, E; Chap, Z | 1 |
| Gibb, W; Lavoie, JC; Roux, JF | 1 |
| Arai, K; Okinaga, S; Sano, Y; Shibusawa, H; Yoshida, N | 1 |
| Yoshida, N | 1 |
| Cekan, Z; Diczfalusy, E; Guerrero, R; Landgren, BM; Montiel, R | 1 |
| Jaffe, RB; Payne, AH | 3 |
| Deshpande, N; Yates, J | 2 |
| Bertamino, R; Crovato, F; Moretti, G | 1 |
| Fulgheri, FD; Lupo di Prisco, C | 1 |
| Bedford, CA; Heap, RB; Linzell, JL | 1 |
| Danishefsky, S; Nagasawa, K; Wang, N | 1 |
| Laatikainen, T; Peltonen, J | 1 |
| Brachet, PH; Klein, C | 1 |
| Brenner, PF; Cekan, Z; DICZFALUSY, E; Landgren, BM; Purvis, K | 1 |
| Cekan, Z; Diczfalusy, E; Landgren, BM; Purvis, K | 2 |
| Fehér, T; Györy, G; Kiss, C; Poteczin, E | 1 |
| Gontscharow, NP; Jefremova, SK; Schön, R; Schubert, K; Simarina, AJ | 1 |
| Cooper, TG; Waites, GM | 1 |
| Cameron, EH; Collins, W | 1 |
| Bell, JB | 1 |
| Friedrich, E; Schindler, AE | 1 |
| Schindler, AE; Sparke, H | 2 |
| Couch, RA; Doouss, TW; Skinner, SJ | 1 |
| Ainsworth, L; Nitchuk, WM | 1 |
| Schindler, AE; Wuchter, J | 1 |
| Leathem, JH; Murono, EP | 1 |
| Deshpande, N | 2 |
| Abraham, GE; Chakmakjian, ZH | 2 |
| Goebelsmann, U; Hall, TD; Paul, WL; Stanczyk, FZ | 1 |
| Aso, T; Brenner, PF; Cekan, Z; Diczfalusy, E; Guerrero, R; Hagenfeldt, K; Landgren, BM | 1 |
| Benagiano, G; de la Torre, B; Diczfalusy, E | 1 |
| Wiebe, JP | 2 |
| Brinkley, HJ; Weiss, JR; Young, EP | 1 |
| Remezova, MI; Shashkina, LF; Starkov, MV | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N; Pachalia, N | 1 |
| Aso, T; Cekan, Z; Diczfalusy, E; Goncharov, N | 1 |
| Goldman, AS; Katsumata, M | 1 |
| Abraham, GE; Maroulis, GB | 2 |
| Cekan, Z; Diczfalusy, E; Landgren, BM; Purvis, K; Saksena, SK | 1 |
| Cekan, Z; Diczfalusy, E; Giner, J; Purvis, K; Saksena, SK | 1 |
| Forrest, AP; Miller, WR; Shivas, AA | 1 |
| Carson, P; Deshpande, N; Di Martino, L; Tarquini, A | 1 |
| Cekan, SZ; Diczfalusy, ER; Landgren, BM; Purvis, K; Saksena, SK | 1 |
| Belvedere, PC; Colombo, L | 1 |
| Armstrong, DG; Wells, JW | 1 |
| Bloch, E; Gupta, C | 1 |
| Gustafsson, SA | 1 |
| Sanyal, MK; Villee, CA | 1 |
| Carson, P; Deshpande, N; Mitchell, I; O'Higgins, NJ | 1 |
| Mori, T | 1 |
| Burton, RD; Gadsby, JE; Heap, RB; Perry, JS | 1 |
| Aedo, AR; Cekan, SZ; Diczfalusy, E; Landgren, BM; Nuñez, M | 1 |
| Aso, T | 1 |
| Rodbard, D | 1 |
| Eastman, AR; Neville, AM | 1 |
| Litwack, G; Ohl, VS | 1 |
| Mori, T; Nishimura, T; Suzuki, A | 1 |
| French, FS; Guerrero, R; Hansson, V; Purvis, K; Ritzen, EM | 1 |
| Lance, V; Lofts, B | 1 |
| Antila, E; Koskinen, J; Niemela, P; Saure, A | 1 |
| Chang, MC; Lau, IF; Saksena, SK | 2 |
| Doerr, P; Pirke, KM; Sintermann, R; Vogt, HJ | 1 |
| Diczfalusy, E | 1 |
| Aedo, AR; Aso, T; Cekan, SZ | 1 |
| de la Torre, B; Diczfalusy, E; Hedman, M | 1 |
| Calvert, ME; Gant, NF; MacDonald, PC; Milewich, L | 1 |
| Legrand, C | 1 |
| McIntosh, JE; Phillipou, G; Seamark, RF | 1 |
| Preslock, JP; Steinberger, E | 4 |
| Den, M; Haruyama, N; Takasaki, T; Uesato, T; Yoshida, T | 1 |
| Fern, EB; Fern, M; Rose, DP | 1 |
| Bonaventura, LM; Cleary, RE; Judd, H; Roth, LM | 1 |
| Abraham, GE; Bossen, EH; Soules, MR | 1 |
| Ruokonen, A | 1 |
| Choi, SK; Diczfalusy, E; Rajalakshmi, M; Robertson, DM | 1 |
| Lau, IF; Saksena, SK | 2 |
| Buster, JE; Elsner, CW; Killam, AP; Preston, DL | 1 |
| Hammond, GL; Koivisto, M; Kouvalainen, K; Vihko, R | 1 |
| Kovarik, FA; Velardo, JT | 1 |
| Govaerts, M; Preumont, P; Schwers, J; Vancrombreucq, T | 1 |
| Cedard, L; Guichard, A; Haffen, K; Mignot, TM; Scheib, D | 1 |
| Bator, JM; Baukal, AJ; Catt, KJ; Cigorraga, SB; Dufau, ML; Neubauer, JF; Sorrell, SH | 1 |
| Shimizu, K | 3 |
| Gandelman, R; McDermott, NJ; Simon, NG | 1 |
| Abul-Hajj, YJ; Iverson, R; Kiang, DT | 1 |
| Iida, M; Iizuka, H; Shinozuka, T | 1 |
| Bertrand, J; Cadillon, E; de Peretti, E | 1 |
| Corda, R; Genazzani, AR; Pintor, C | 1 |
| Isherwood, DM; Oakey, RE | 1 |
| Giroud, CJ; Goodyer, CG; Hall, CS; Smith, BT; Torday, JS | 1 |
| Lauritzen, C; Lehmann, WD | 1 |
| Anderson, DC; Yen, SS | 1 |
| Gibb, W; Hagerman, DD | 1 |
| Davajan, V; Goebelsmann, U; Israel, R; Mestman, JH; Mishell, DR; Zachmann, M | 1 |
| Bussmann, L; Huseby, RA; Samuels, LT | 1 |
| Bayer, JM; Breuer, H; Lisboa, BP; Nocke-Finck, L; Strassner, M | 1 |
| Carr, BR; MacDonald, PC; Milewich, L; Parker, CR; Porter, JC; Simpson, ER | 2 |
| Kahri, AI; Salmenperä, M; Voutilainen, R | 1 |
| Corda, R; Facchinetti, F; Genazzani, AR; Inaudi, P; Maci, D; Pintor, C | 1 |
| Horino, M; Kakita, K; Matsuki, M; Matsumura, S; Nishida, S; Omukai, Y; Oyama, H; Tanaka, H; Tenku, A | 1 |
| Olson, DR; Shroff, JR; Weinryb, I | 1 |
| Andrada, JA; Hoscholan, JC | 1 |
| Kominami, S; Nawa, K; Takemori, S; Yamazaki, T | 1 |
| Baulieu, EE; Corpéchot, C; Egestad, B; Morfin, R; Sjövall, J; Young, J | 1 |
| Chew, PC; Chow, WP; Gunasegaram, R; Loganath, A; Peh, KL; Shanmugaratnam, S | 1 |
| Cooke, GM; Hébert, P | 1 |
| Bélanger, A; Bélanger, B; Roy, R | 1 |
| Akwa, Y; Baulieu, EE; Morfin, RF; Robel, P | 1 |
| Baulieu, EE; Eychenne, B; Jo, DH; Lapous, D; Raulin, J; Robel, P; Vourc'h, C | 1 |
| Flood, JF; Morley, JE; Roberts, E | 1 |
| Baulieu, EE; Corpéchot, C; Gobaille, S; Haug, M; Robel, P; Young, J | 1 |
| Arlotto, MP; Barnes, HJ; Waterman, MR | 1 |
| de Launoit, Y; Labrie, F; Simard, J | 1 |
| Benahmed, M; Chauvin, MA; de Peretti, E; Mauduit, C; Morera, AM | 1 |
| Desvages, G; Pieau, C | 1 |
| Akwa, Y; Hu, ZY; Jo, DH; Jung-Testas, I; Kabbadj, K; Le Goascogne, C; Sancho, MJ; Vourc'h, C; Young, J; Zucman, D | 1 |
| Hochberg, RB; Larner, JM; Pahuja, SL; Zielinski, JE | 1 |
| Hirato, K; Hondo, T; Saito, H; Suzuki, T; Yanaihara, T | 1 |
| Cooke, GM | 1 |
| Lorence, MC; Mason, JI; Murry, BA; Trant, JM | 1 |
| Chibbar, R; Mitchell, BF | 1 |
| López-Solache, I; Mendoza-Hernández, G; Rendón, JL | 1 |
| Bar-Ami, S; Brandes, JM; Gitay-Goren, H | 1 |
| Baulieu, EE; Halberg, F; Jo, DH; Robel, P; Sánchez de la Peña, S; Ungar, F | 1 |
| Jalkanen, J | 1 |
| Estabrook, RW; Johnson, EF; Lorence, MC; Mason, JI; Shackleton, CH; Trant, JM | 1 |
| Hirato, K; Yanaihara, T | 1 |
| Bélanger, A; Bélanger, B; Caron, S; Dupont, A | 1 |
| Imataka, H; Inano, H; Kohmoto, K; Suzuki, K; Tamaoki, B | 1 |
| Hobkirk, R; Raeside, JI; Renaud, R | 1 |
| Flury, A; Olivier, NS; Patrito, LC; Raimondi, SG | 1 |
| Abdallah, MA; Baulieu, EE; Jo, DH; Robel, P; Young, J | 1 |
| Jalkanen, M; Pankakoski, E; Tähkä, KM; Teräväinen, T | 1 |
| Benahmed, M; Chauvin, MA; de Peretti, E; Morera, AM; Sordoillet, C | 1 |
| Adamo, MV; Balducci, R; Boscherini, B; Cives, C; Mangiantini, A; Toscano, V | 1 |
| McCarthy, JL; Waterman, MR | 1 |
| Fenske, M | 1 |
| Gautier, T; Imperato-McGinley, J; Peterson, RE; Shackleton, C | 1 |
| Guichard, A; Mignot, TM; Reyss-Brion, M; Scheib, D | 1 |
| De Clerck, D; De Loof, A; Diederik, H; Ollevier, F | 1 |
| Lambert, JG; Schoonen, WG | 1 |
| Nowotny, P; Vierhapper, H; Waldhäusl, W | 1 |
| Benveniste, R; Ilekis, J; Moise, J; Scommegna, A | 1 |
| Deslypere, JP; Vermeulen, A | 1 |
| Drife, JO | 1 |
| Godfrey, BM; Petrucco, OM; Seamark, RF; Stone, BA | 1 |
| Lanthier, A; Patwardhan, VV | 3 |
| de la Torre, B; Hedman, M; Norén, S; Sjöberg, B | 1 |
| Gunasegaram, R; Kottegoda, SR; Loganath, A; Ng, SC; Peh, KL; Ratnam, SS | 1 |
| Hirato, K; Nakayama, T; Yanaihara, T | 1 |
| Baulieu, EE; Halberg, F; Robel, P; Synguelakis, M | 1 |
| Ali, SA; Lambert, JG; Schoonen, WG; Van den Hurk, R; Van Oordt, PG | 1 |
| Benais, JP; Bonete, R; Dreux, C; Fiet, J; Gourmel, B; Gueux, B; Lacroix, C; Villette, JM | 1 |
| Bourreau, E; Clarke, C; Corpéchot, C; Dang, DC; Halberg, F; Haug, M; Robel, P; Schlegel, ML; Synguelakis, M; Vourch, C | 1 |
| Walsh, SW | 1 |
| Kakumoto, Y; Kamiya, T; Kiryu, Y; Maruyama, T; Nakamoto, H; Ookawa, H; Suzuki, O; Yasui, T; Yasumura, K; Yokomori, H | 1 |
| Hashino, M; Nakayama, T; Suzuki, H; Yanaihara, T | 1 |
| Bygdeman, M; de la Torre, B; Gottlieb, C; Hedman, M; Svanborg, K | 1 |
| Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F | 1 |
| Baulieu, EE; Haug, M; Ouss-Schlegel, ML; Robel, P; Spetz, JF | 1 |
| Heath, DA; Henderson, KM; Kieboom, LE; Lun, S; McNatty, KP | 1 |
| Singh, S; Singh, TP | 1 |
| Vagramian, ER | 1 |
| Crabbe, J; Kolanowski, J; Ortega, N | 2 |
| Gunasegaram, R; Kottegoda, SR; Loganath, A; Peh, KL; Ratnam, SS; Thiagaraj, D | 1 |
| Maki, T | 1 |
| Bermúdez, JA; Flores, M; Herrera, J; Martin, O; Medina, M; Zárate, A | 1 |
| Carr, BR; Mason, JI; Rainey, WE | 1 |
| Berthezene, F; Boizel, R; Bost, M; Cathiard, AM; de Peretti, E; Halimi, S; Saez, JM | 1 |
| Gennings, JN; Gower, DB; Hancock, MR | 1 |
| Aida, K; Asahina, K; Hibiya, T; Suzuki, K; Tamaoki, B | 1 |
| Byrne, GC; Perry, YS; Winter, JS | 1 |
| Narita, O; Okuyama, S; Takagi, K; Tomoda, Y; Wu, MC | 1 |
| James, VH; Jones, DL | 1 |
| Ramakrishnan, S; Veeraragavan, K | 1 |
| Gower, DB; Kwan, TK; Taylor, NF; Watson, D | 1 |
| Hori, D | 1 |
| Alén, M; Bolton, N; Ruokonen, A; Vihko, R | 1 |
| Seamark, RF; Stone, BA | 1 |
| Aakvaag, A | 1 |
| Kellie, AE; Riley, WJ; Robertson, DM; Smith, ER | 1 |
| Gontscharow, NP; Komor, A; Schön, R; Schubert, K; Wehrberger, K | 1 |
| Boettcher, B; Kay, DJ | 1 |
| Bedrak, E; Samoiloff, V; Sod-Moriah, UA | 1 |
| O, R; Tamaoki, BI | 1 |
| Oh, R; Tamaoki, B | 1 |
| Andersen, RN; Givens, JR; Pittaway, DE | 1 |
| Nozu, K; Tamaoki, B | 1 |
| Altman, FP; Bitensky, L; Butcher, RG; Chayen, J | 1 |
| Katukawa, H; Nakamura, T; Tanabe, Y | 1 |
| Camara, SA; Cardinali, DP; Diéguez, ME; Rosner, JM | 1 |
| Menini, E; Norymberski, JK | 1 |
| David, RR; Landau, RL; Ross, L; Wiener, M | 1 |
| Yaron, Z | 1 |
| Burgett, MJ; Slaunwhite, WR | 1 |
| Breuer, H; Dahm, K; Döllefeld, E; Stárka, L; Sulcová, J | 1 |
| Oertel, GW; Rindt, W; Weinand, K | 1 |
| Vihko, R | 1 |
| van Leusden, HA; Villee, CA | 1 |
| Heap, RB; Holzbauer, M; Newport, HM | 1 |
| Grant, JK; Griffiths, K; Pierrepoint, CG; Stewart, JS | 1 |
| Bongiovanni, AM | 1 |
| Ainsworth, L; Ryan, KJ | 1 |
| Bandi, L; Calvin, HI; Cos, JJ; Lieberman, S; Roberts, KD; Weiss, C | 1 |
| Ahmad, N; Cleveland, WW; Politano, VT; Rice, BF; Sandberg, DH; Savard, K | 1 |
| Galley, JM; Grant, JK; Griffiths, K; Pierrepoint, CG | 1 |
| Schuetz, AW | 1 |
| Cheatum, SG; Watten, JC | 1 |
| Cheatum, SG; Douville, AW; Warren, JC | 1 |
| Chieffi, G; Delrio, G; Lupo di Prisco, C | 1 |
| Giroud, CJ; Klein, GP | 1 |
| Ochi-Ai, K; Oshima, H; Sarada, T; Tamaoki, BI | 1 |
| Hahn, BD; Plotz, EJ; Stein, AA; Wiener, M | 1 |
| Bulbrook, RD; Deshpande, N; Doouss, TW; Jensen, V | 2 |
| Brownie, AC; Hoschoian, JC | 2 |
| Bulbrook, RD; Coombs, MM; Ellis, F; Wang, DY | 1 |
| Bulbrook, RD; Wang, DY | 1 |
| Oakey, RE; Shahwan, MM; Stitch, SR | 4 |
| Bruni, V; Forleo, R; Ingiulla, W; Sbiroli, C | 1 |
| Jaffe, RB; Pérez, AE; Perez-Palacios, G | 1 |
| Sjövall, J; Vihko, R | 1 |
| Christie, GA | 1 |
| Greenough, L; Rettig, J; Villee, DB | 1 |
| Teller, WM | 1 |
| Ebersohl, C; Oertel, GW; Rindt, W | 1 |
| Bieri, JG; Rogers, WE | 1 |
| Diczfalusy, E; Lowy, J; Pasqualini, JR; Wiqvist, N | 1 |
| Bohus, B; Lissák, K; Strashimirov, D | 1 |
| Chieffi, G; Delrio, G; Di Prisco, CL | 1 |
| Ahmad, N; Gower, DB | 1 |
| Rubin, BL | 2 |
| Laatikaninen, T; Peltokallio, P; Vihko, R | 1 |
| Deshpande, N; Doouss, TW | 1 |
| Tsuda, M | 1 |
| Dao, TL; Libby, PR | 2 |
| Lisse, K; Schürenkämper, P | 2 |
| Adams, JB; Edwards, AM | 1 |
| Leymarie, P; Savard, K | 1 |
| Jungmann, RA; Schweppe, JS | 1 |
| Givner, ML; Jaffe, RB; Lamont, KG; Pérez-Palacios, G | 1 |
| Charreau, E; Villee, CA | 1 |
| Boström, H; Brömster, D; Nordenstam, H; Wengle, B | 1 |
| Laatikainen, T; Laitinen, EA; Vihko, R | 1 |
| Hörhold, C; Kaufmann, G; Schubert, K | 1 |
| Cooke, BA | 1 |
| Anderson, JM; McCormick, MH; Neville, AM; Webb, JL | 1 |
| Heinrichs, WL; Herrmann, WL; Karsznia, R; Wyss, RH | 1 |
| Ainsworth, L; Daenen, M; Ryan, KJ | 1 |
| Garcia, O; Green, OC; Hamwi, GJ; Miller, RR | 1 |
| Dixon, R; Hochberg, RB; Mickan, H | 1 |
| Jaffe, RB; Lamont, KG; Pérez, AE; Pérez-Palacios, G; Pierce, GB | 1 |
| Notation, AD; Ungar, F | 4 |
| Rappaport, R | 1 |
| Axelrod, LR; Goldzieher, JW; Lecocq, FR | 1 |
| Jänne, O; Sjövall, J; Sjövall, K; Vihko, R | 1 |
| Knapstein, P; Touchstone, JC | 1 |
| Desplanques, D; Grangaud, R; Nicol, M | 1 |
| Conti, C; Sciarra, F | 1 |
| Piro, C; Sciarra, F; Sorcini, G | 1 |
| Laatikainen, T; Vihko, R | 4 |
| Fevold, HR; Wright, PL | 1 |
| Tamaoki, BI | 1 |
| Calman, KC; Grant, JK; Milne, JA | 1 |
| Anderson, AB; Cameron, EH; Griffiths, K; Jones, D; Jones, T | 1 |
| Cardinali, DP; Macome, JC; Rosner, JM | 1 |
| Emerson, K; Rose, LI; Villee, DB; Williams, GH | 1 |
| Bardin, CW; Gallup, J; LeMaire, WJ; Marshall, J; Rosen, S; Savard, K; Tjio, JH | 1 |
| Macome, JC; Rosner, JM | 1 |
| Esteban-Altirriba, J; Oriol-Bosch, A; Prats-Viñas, J; Pujol-Amat, P; Ribas-Mundo, J; Tejero, A; Venrell-Diaz, J | 1 |
| Hanson, JR; Organ, TD | 1 |
| Kalliala, K; Laatikainen, T; Luukkainen, T; Vihko, R | 1 |
| Eckstein, B | 1 |
| Eriksson, H; Gustafsson, JA | 1 |
| Carlström, K; Furuhjelm, M | 1 |
| Tabei, T | 1 |
| Huhtaniemi, I; Ikonen, M; Vihko, R | 1 |
| Davies, IJ; Petro, Z; Ryan, KJ | 1 |
| Feldman, MK; Fowler, EH | 1 |
| Chieffi, G; Lupo di Prisco, C; Materazzi, G | 1 |
| Lucis, OJ; Lucis, R | 1 |
| Bulbrook, RD; Carson, P; Deshpande, N; Doouss, TW; Jensen, V | 1 |
| Daly, JR; Gower, DB; Snodgrass, GJ; Stern, MI | 1 |
| Huhtaniemi, I; Luukkainen, T; Vihko, R | 1 |
| Eik-Nes, KB; Frankel, AI | 1 |
| Collins, WP; Flamigni, CA; Koullapis, EN; Sommerville, IF | 1 |
| Cooke, BA; Cowan, RA; Taylor, PD | 1 |
| Mills, IH; Milner, AJ | 1 |
| Brown, PS | 1 |
| Dorfman, RI; Gottfried, H | 2 |
| Cameron, EH; Griffiths, K; Hammerstein, J; Jones, D; Morris, S | 1 |
| Jaffe, RB; Lamont, KG; Pérez, AE; Pérez-Palacios, G | 1 |
| Huhtaniemi, I; Vihko, R | 3 |
| Chen, C; Gill, W | 1 |
| Brooksbank, BW | 1 |
| Askari, HA | 1 |
| Ances, IG; Ganis, FM; Haskins, AL | 1 |
| Idler, DR; O'Halloran, MJ | 1 |
| Baird, DT; Lloyd, CW; Lobotsky, J; McCracken, JA; Puga, J; Pupkin, M; Weisz, J; Zanartu, J | 1 |
| Merkatz, I; Solomon, S | 1 |
| Bodin-Lefevre, J; Galbois, A; Grangaud, R; Le Treut, A; Nicol, M | 1 |
| Bleau, G; Chapdelaine, A; Roberts, KD | 1 |
| Bourneva, V; Motta, P | 1 |
| Hoffmann, B; Karg, H | 1 |
| Sarada, T | 1 |
| Archer, DF; Diczfalusy, E; Mathur, RS; Wiqvist, N | 1 |
| Laatikainen, T | 1 |
| Atsuta, A | 1 |
| Osinski, PA; Van Damme, MP | 1 |
| Bloch, E; Klein, M; Lew, M | 1 |
| Francis, FE; Kinsella, RA | 1 |
| Motta, P; Takeva, Z | 1 |
| Tam, WH | 1 |
| France, JT | 1 |
| Jonas, A; Menzel, P | 1 |
| Chayes, R; Dvir, R; Gould, S; Harell, A | 1 |
| Carson, P; Deshpande, N; Harley, S | 1 |
| Charles, D; Chattoraj, SC; Fanous, R; Pinkus, JL | 1 |
| Allison, JE; Bardin, CW; Gumbreck, LG; Schneider, G; Stanley, AJ; Vanha-Perttula, T | 1 |
| Carr, BR; Flickinger, GL; Mikhail, G | 1 |
| Ances, IG; Connor, TB; Gallaher, EP; Ganis, FM; Levin, HS; Migeon, CJ | 1 |
| Bicknell, DC; Gower, DB | 1 |
| Jaffe, RB; Pérez-Palacios, G; Serra, GB | 1 |
| Green, OC; Kenny, FM; Reynolds, JW | 1 |
| Cooke, BA; Dobbie, J; Shirley, IM; Taylor, PD | 1 |
| Cooke, BA; Taylor, PD | 1 |
| Selye, H; Szabo, S; Taché, Y | 1 |
| Gandar, R; Menzel, P; Oertel, GW; Rindt, W; Seidel, W | 1 |
| Braunberger, G; Menzel, P; Oertel, GW; Rindt, W | 1 |
| Kono, K | 1 |
| Erpino, MJ | 1 |
| Choy, LY; Lofts, B | 1 |
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| CLARK, AF; SOLOMON, S | 1 |
| CSILLAG, M; FAJTHA, F; SAJGO, M | 1 |
| JARRIGE, P; JAYLE, MF; YON, J | 1 |
| GOTTFRIED, H; SIMPSON, TH; WRIGHT, RS | 1 |
| LEVENTHAL, ML; SCOMMEGNA, A | 1 |
| GIORGI, EP | 1 |
| DEPAOLI, J; EIK-NES, B | 1 |
| BAULIEU, EE; LEBEAU, MC | 1 |
| ADAMS, JB | 1 |
| WENGLE, B | 1 |
| CALVIN, HI; LIEBERMAN, S | 1 |
| AAKVAAG, A; EIK-NES, KB | 1 |
| JANATA, J; STARKA, L | 1 |
| GOSPODAROWICZ, D | 2 |
| DORFMAN, RI; SHARMA, DC | 1 |
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| CONRAD, SH; KASE, N | 1 |
| KASE, N | 1 |
| BORKOWF, HI; GOLDBERG, B; JONES, GE | 1 |
| BECK, SD; JENNY, NA; SMISSMAN, EE | 1 |
| KILLINGER, DW; SOLOMON, S | 1 |
| LORING, JM; VILLEE, CA | 1 |
| BETZ, G; WARREN, JC | 1 |
| CRAWFORD, JD; KLIMAN, B; MACGILLIVRAY, M; SCULLY, RE; VILLEE, DB | 1 |
| ARCOS, M; LIEBERMAN, S | 1 |
| BOMPIANI, A; KAHNT, FW; NEHER, R; ROVERSI, GD | 1 |
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| SCHEDEWIE, H; TAMM, J; VOIGT, KD; VOLKWEIN, U | 1 |
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| GREENBLATT, RB; MAHESH, VB | 1 |
| Chang, LL; Ho, LL; Wang, PS; Wun, WS | 1 |
| Kamei, H; Nabeshima, T; Noda, Y; Yamada, K | 1 |
| Diallo, S; Greeson, J; Lecanu, L; Papadopoulos, V | 1 |
| Enami, T; Furukawa, A; Harada, N; Hattori, TA; Hojo, Y; Ishii, HT; Janssen, WG; Kawato, S; Kimoto, T; Kominami, S; Morrison, JH; Mukai, H; Suzuki, K | 1 |
| Azziz, R; Boots, LS; Moran, C; Reyna, R | 1 |
| Kamei, H; Manh Tran, H; Maurice, T; Nabeshima, T; Nagai, T; Noda, Y; Roman, FJ; Romieu, P; Urani, A; Yamada, K | 1 |
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| Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Pouzar, V; Stárka, L; Vrbíková, J | 2 |
| Hou, YN; Ren, JM | 1 |
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| Doron, R; Gispan-Herman, I; Lotan, S; Maayan, R; Shabat-Simon, M; Weizman, A; Yadid, G | 1 |
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| Blazer, DG; Butterfield, MI; Ervin, JF; Hulette, CM; Lieberman, JA; Marx, CE; Massing, MW; Shampine, LJ; Steffens, DC; Stevens, RD; Trost, WT | 1 |
| Dumas, N; Falany, CN; Falany, JL; Frost, AR; He, D | 1 |
| Gibel, A; Maayan, R; Ritsner, M; Weizman, A | 1 |
| Hamann, M; Richter, A; Richter, F | 1 |
| Dubnau, E; Sampson, NS; Smith, I; Yang, X | 1 |
| Mellon, SH | 1 |
| Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M | 1 |
| Dhir, A; Kulkarni, S | 1 |
| Chang, LL; Wang, PS; Wun, WS | 1 |
| Biggio, G; Concas, A; Marotto, MF; Marra, C; Marrosu, F; Melis, GB; Orrù, M; Paoletti, AM; Sogliano, C; Tuveri, A; Zedda, P | 1 |
| Blazer, DG; Calhoun, PS; Calnaido, RP; Ervin, JF; Hulette, CM; Kilts, JD; Lieberman, JA; Madison, RD; Marx, CE; Massing, MW; Naylor, JC; Payne, VM; Shampine, LJ; Steffens, DC; Strauss, JL | 1 |
| Fernández Presas, AM; Romano, MC; Valdez, RA; Willms, K | 1 |
| Kołek, T; Swizdor, A; Szpineter, A | 2 |
| Budziszewska, B; Jantas, D; Lason, W; Leskiewicz, M | 1 |
| Coyle, E; Dedi, C; Dodd, HT; Hunter, AC; Koussoroplis, SJ; Morse, F | 1 |
| Caruso, D; Garcia-Segura, LM; Giatti, S; Maschi, O; Melcangi, RC; Pesaresi, M | 1 |
| Baulieu, EE; Bodin, K; Cambourg, A; Eychenne, B; Griffiths, W; Liere, P; Pianos, A; Schumacher, M; Sjövall, J | 1 |
| Iwata, M; Muneoka, K; Shirayama, Y | 1 |
| Doeswijk, TG; Essers, ML; Groot, MJ; Lommen, A; Nielen, MW; Rijk, JC; Van Hende, JM | 1 |
| Kallonen, SE; Ketola, RA; Kostiainen, R; Piepponen, P; Raattamaa, H; Tammimäki, A | 1 |
| Bhuiyan, S; Burgess, M; Kurogi, K; Liu, MC; Liu, MY; Sakakibara, Y; Suiko, M; Williams, FE; Yasuda, S; Yasuda, T | 1 |
| Ritsner, MS | 1 |
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| Chen, W; Sheu, HM; Tsai, JC; Tsai, SJ; Zouboulis, CC | 1 |
| Boguslavsky, I; Gibel, A; Lerner, V; Maayan, R; Ritsner, MS; Shleifer, T; Weizman, A; Zayed, A | 1 |
| Ballatori, N; Christian, WV; Cui, M; Fang, F; Gorman, SG; Huang, J; Tieu, K | 1 |
| Elfverson, M; Johansson, T; Nyberg, F; Zhou, Q | 1 |
| Bose, HS; Gairola, CG; McKenzie, KA; Pawlak, KJ; Prasad, M; Whittal, RM; Wiebe, JP | 1 |
| Chrastina, J; Hill, M; Kancheva, L; Kancheva, R; Novák, Z; Stárka, L | 1 |
| Agustí, A; Cauli, O; Felipo, V; González-Usano, A | 1 |
| Balk, SP; Bubley, GJ; Cai, C; Chen, S; Marck, B; Matsumoto, AM; Mostaghel, EA; Nelson, PS; Ng, P; Simon, NI; Wang, H | 1 |
| Girdler, SS; Johnson, JL; Lindgren, M; Morrow, AL; Porcu, P; Rubinow, DR | 1 |
| Lepschy, M; Möstl, E; Ouschan, C; Zeugswetter, F | 1 |
| Chang, F; Chen, L; Sokabe, M; Xie, G; Xu, B; Yang, R | 1 |
| Aronsson, B; Bergquist, J; Kushnir, MM; Sandstedt, P; Söndergaard, HP | 1 |
| Cui, J; Fan, L; Gan, C; Huang, Y; Jiao, Y; Wei, W | 1 |
| Horishita, T; Okura, D; Sata, T; Sudo, Y; Ueno, S; Uezono, Y; Yanagihara, N | 1 |
| Miller, WL; Nebert, DW; Wikvall, K | 1 |
| Gao, H; Qiao, MQ; Xia, T | 1 |
| Chen, HL; Du, JJ; Li, YC | 1 |
| Lucchi, C; Pinetti, D; Puia, G; Ravazzini, F; Rustichelli, C | 1 |
| Bernhardt, R; Schmitz, D; Zapp, J | 1 |
| Bingsohn, L; Dezhkam, Y; Failing, K; Galuska, CE; Hartmann, MF; Hoffmann, B; Sánchez-Guijo, A; Schuler, G; Wudy, SA | 1 |
| Aksoy-Poyraz, C; Bolayırlı, M; Savrun, M; Turan, Ş; Yıldırım, A | 1 |
| Duffel, MW; Qin, X; Squirewell, EJ | 1 |
| DeVore, NM; Petrunak, EM; Porubsky, PR; Scott, EE | 1 |
| Allen, TB; Bradford, DW; Brancu, M; Brunca, M; Hamer, RM; Kilts, JD; Marx, CE; Naylor, JC; Shampine, LJ; Strauss, JL; Szabo, ST; Youssef, NA | 1 |
| Tennant, F | 1 |
| Bernhardt, R; Gerber, A; Hannemann, F; Mosa, A; Neunzig, J; Pilak, P; Zapp, J | 1 |
| Ben Dor, R; Marx, CE; Rubinow, DR; Schmidt, PJ; Shampine, LJ | 1 |
| Bergquist, J; Hreinsson, J; Kushnir, MM; Meikle, AW; Naessén, T; Rockwood, AL; Wanggren, K | 1 |
| Bergquist, J; de Kock, N; Fallahsharoudi, A; Jensen, P; Johnsson, M; Ubhayasekera, SJ; Wright, D | 1 |
| Hallman, M; Khashana, A; Leskinen, M; Ojaniemi, M; Saarela, T | 1 |
| Denisov, IG; Gregory, MC; Kincaid, JR; Mak, PJ; Sligar, SG | 1 |
| Dušková, M; Hill, M; Rácz, B; Šrámková, M; Stárka, L; Vondra, K | 1 |
| Dzugan, KS; Dzugan, SA | 1 |
| Alhusainy, W; Amer, AO; Jones, DE; Palmer, JM; Probert, PM; Rietjens, IM; White, SA; Wright, MC | 1 |
| Bues, B; Calignano, A; Carotenuto, A; Cerillo, I; Mangone, G; Orefice, G; Orefice, N; Rehm, R; Saccà, F | 1 |
| Dušková, M; Hána, V; Jandíková, H; Kosák, M; Kršek, M; Pospíšilová, H; Šimůnková, K; Sosvorová, L; Springer, D; Šrámková, M; Stárka, L; Vítků, J; Žánová, M | 1 |
| Auriola, S; Häkkinen, MR; Kärkkäinen, O; Kautiainen, H; Storvik, M; Tiihonen, J | 1 |
| Choi, MH; Chung, BC; Kim, SH; Lee, J; Lee, SH; Lee, WY; Park, MJ | 1 |
| Bernhardt, R; Gerber, A; Hartmann, MF; Neunzig, J; Oji, V; Sánchez-Guijo, A; Schuppe, HC; Traupe, H; Wudy, SA | 1 |
| Chang, CH; Chen, HL; Chu, CL; Lee, SY; Lin, SH; Lu, RB; Lu, T; Wang, LJ; Wu, CC | 1 |
| Abdelwahab, A; Ahmed, A; Ahmed, H; Hallman, M; Khashana, A; Rämet, M; Saarela, T | 1 |
| Chen, CC; Chong, MY; Hsu, ST; Huang, YC; Hung, CF; Lee, Y; Lin, CH; Lin, PY; Wang, LJ; Wu, CC | 1 |
| Ball, BA; Conley, AJ; Corbin, CJ; Legacki, EL; Loux, SC; Scoggin, KE; Stanley, SD | 1 |
| Cai, H; Dougherty, GG; Haas, GL; Keshavan, M; Montrose, DM; Reddy, RD; Yao, JK; Zhou, X | 1 |
| Abunnaja, MS; Alherz, FA; Bairam, AF; El Daibani, AA; Gohal, SA; Kurogi, K; Liu, MC; Rasool, MI; Sakakibara, Y; Suiko, M | 1 |
| Baulieu, EE; Froger, N; Lanfumey, L; Schverer, M; Villey, I | 1 |
| Hartmann, MF; Sánchez-Guijo, A; Tiosano, D; Wang, R; Wudy, SA | 1 |
| Dai, Y; Li, X; Liu, D; Wang, D; Wu, B; Wu, M; Xia, M; Xu, D; Yu, Q | 1 |
| Abunnaja, MS; Alherz, FA; Bairam, AF; El Daibani, AA; Kurogi, K; Liu, MC; Rasool, MI; Sakakibara, Y; Suiko, M | 1 |
| Faletrov, YV; Frolova, NS; Panada, JU; Shkumatov, VM | 1 |
| Aleman, M; Chigerwe, M; Madigan, JE; McCue, PM | 1 |
| Alyamani, M; Bohn, K; Chung, YM; Klein, EA; McManus, JM; Sharifi, N | 1 |
| Cao, B; Gong, C; Li, W; Liang, X; Liu, M; Meng, X; Qin, M; Su, C; Wei, L; Wu, D | 1 |
| Bian, C; Chen, L; Chen, X; Gao, Y; Hou, Z; Huang, S; Hydyr, N; Le, W; Li, Z; Lian, J; Liu, Y; Mei, Z; Tan, Q; Wu, D; Xu, C; Yang, T; Zhang, S; Zhu, X | 1 |
| Li, Y; Yuan, T | 1 |
| Denisov, IG; Gregory, MC; Grinkova, Y; Kincaid, JR; Liu, Y; Sligar, SG | 1 |
| Donova, M; Kazantsev, A; Kollerov, V; Shutov, A | 1 |
| Bae, MA; Cho, SH; Hwang, KS; Kim, JL; Kim, KT; Kim, SS; Park, HC | 1 |
| Babayev, E; Duncan, FE; Shea, LD; Woodruff, TK; Xu, M | 1 |
| Appenzeller, BMR; Palazzi, P; Peng, FJ; Viguié, C | 1 |
| Bragin, EY; Donova, MV; Epiktetov, DO; Fokina, VV; Karpov, MV; Kazantsev, AV; Kollerov, VV; Shutov, AA; Sviridov, AV | 1 |
| Bouty, A; Dijoud, F; Ecochard, R; Mallet, D; Mouriquand, P; Mure, PY; Plotton, I; Pourquet, A; Renault, L; Rigaud, C; Roucher, F; Sanlaville, D; Teoli, J | 1 |
| An, BS; An, SM; Jeong, JS; Kim, DS; Kim, MJ; Kim, SC; Kim, SY | 1 |
50 review(s) available for dehydroepiandrosterone and pregnenolone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Studies on steroids in urine of the male newborn.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Arylsulfatases; Dehydroepiandrosterone; Glucuronidase; Humans; Hydrolysis; Hydroxyprogesterones; Infant, Newborn; Male; Pregnanediol; Pregnanes; Pregnanolone; Pregnenolone; Progesterone | 1975 |
Metabolic and analytic considerations in the design of immunoassays.
Topics: Amitriptyline; Animals; Anti-Arrhythmia Agents; Cyclic AMP; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Immunoassay; Nortriptyline; Pharmaceutical Preparations; Piperazines; Pregnenolone; Testosterone | 1979 |
Neurosteroids: biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain.
Topics: Animals; Brain; Circadian Rhythm; Dehydroepiandrosterone; Female; Male; Pregnenolone; Rats | 1991 |
Steroidal fatty acid esters.
Topics: Adrenal Glands; Androgens; Animals; Cholesterol Esters; Corticosterone; Dehydroepiandrosterone; Esters; Estrogens; Fatty Acids; Pregnenolone; Rats; Solubility; Steroids | 1991 |
Breast development in puberty.
Topics: Adipose Tissue; Adolescent; Adult; Androgens; Breast; Breast Neoplasms; Cell Differentiation; Cell Division; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Replication; Epithelial Cells; Estradiol; Female; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Insulin-Like Growth Factor I; Male; Menarche; Menopause; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Puberty; Risk; Sex Characteristics; Time Factors | 1986 |
[2 surgically treated cases of adrenocortical carcinoma producing steroid hormones without endocrinological symptoms--case report and a review of cases in the Japanese literature].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Carcinoma; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Etiocholanolone; Humans; Male; Pregnenolone | 1988 |
[Role of androgens in the physiology of the reproductive function of women].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Feedback; Female; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophyseal System; Lipoproteins, LDL; Luteinizing Hormone; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Testosterone | 1985 |
Cellular biochemical assessment of steroid activity.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Dehydroepiandrosterone; Densitometry; Endoplasmic Reticulum; Enzymes; Erythrocytes; Estriol; Glucosephosphate Dehydrogenase; Humans; Liver; Lysosomes; Mitochondria; NAD; NADP; Oxidoreductases; Pregnenolone; Protein Binding; Species Specificity; Steroids | 1974 |
[Recent findings on the biosynthesis of adrenal cortex hormones].
Topics: Adrenal Glands; Animals; Cholesterol; Dehydroepiandrosterone; Humans; Pregnenolone | 1967 |
Aspects of corticosteroid biogenesis and metabolism during the perinatal period.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Blood; Congenital Abnormalities; Dehydroepiandrosterone; Female; Fetus; Glucuronates; Humans; Hydrocortisone; Infant, Newborn; Placenta; Pregnancy; Pregnenolone; Somatomedins; Sulfates; Umbilical Cord | 1971 |
[Vitamin A, steroid hormones and nutrition].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Androstanes; Animal Nutritional Physiological Phenomena; Animals; Dehydroepiandrosterone; Estrus; Female; Hydroxysteroid Dehydrogenases; Isomerases; Lipid Metabolism; Male; Nutritional Physiological Phenomena; Ovary; Pregnancy; Pregnenolone; Progesterone; Rabbits; Rats; Rats, Inbred Strains; Testis; Vitamin A; Xerophthalmia | 1970 |
[Biosynthesis of steroids in the corpus luteum. (General review of literature and radioisotope study related to menstrual and pregnancy corpus luteum in humans].
Topics: 17-Ketosteroids; Adult; Androstanes; Carbon Isotopes; Corpus Luteum; Corpus Luteum Hormones; Dehydroepiandrosterone; Female; Humans; Menstruation; Ovary; Pregnancy; Pregnenolone; Progesterone | 1971 |
[Androgens. Biochemistry, pharmacodynamics and therapeutic use].
Topics: Anabolic Agents; Androgens; Androstenes; Breast Neoplasms; Carrier Proteins; Dehydroepiandrosterone; Female; Humans; Male; Pregnenolone; Testosterone | 1973 |
[Some diagnostic and therapeutic aspects of adrenal disorders in childhood (author's transl)].
Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Alcohol Oxidoreductases; Aldosterone; Child, Preschool; Cholesterol; Circadian Rhythm; Clinical Enzyme Tests; Cushing Syndrome; Dehydroepiandrosterone; Diagnosis, Differential; Fluorenes; Humans; Hydrocortisone; Infant; Isomerases; Long-Term Care; Mineralocorticoids; Pregnenolone; Progesterone; Testosterone | 1973 |
Congenital adrenal hyperplasia.
Topics: Adrenal Gland Diseases; Adrenal Glands; Androstenedione; Body Height; Dehydroepiandrosterone; Diagnosis, Differential; Estradiol; Female; Fetus; Genitalia, Female; Genitalia, Male; Humans; Hyperplasia; Male; Pregnancy; Pregnenolone; Progesterone; Steroid Hydroxylases; Testosterone | 1973 |
Effects of corticosteroids on connective tissue and fibroblasts.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Betamethasone; Cell Division; Cells, Cultured; Collagen; Connective Tissue; Cortisone; Dehydroepiandrosterone; DNA; Estradiol; Estrone; Femur; Fibroblasts; Hydrocortisone; Mitosis; Prednisolone; Pregnenolone; Progesterone; Protein Biosynthesis; Rats; Ribs; Structure-Activity Relationship; Time Factors; Transcription, Genetic | 1974 |
Hormonally induced alterations in S. aureus.
Topics: Aerobiosis; Alanine; Amino Acids; Anaerobiosis; Androsterone; Animals; Carbon Radioisotopes; Cell Wall; Dehydroepiandrosterone; Diethylstilbestrol; Female; Glutamates; Gonadal Steroid Hormones; Mestranol; Mice; Norethindrone; Pregnenolone; Progesterone; Pyruvates; Rabbits; Staphylococcal Infections; Staphylococcus; Testosterone | 1974 |
The progressive increase in estrogen production in human pregnancy: an appraisal of the factors responsible.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Binding Sites; Dehydroepiandrosterone; Estrogens; Female; Fetus; Humans; Hydrocortisone; Liver; Maternal-Fetal Exchange; Models, Biological; Placenta; Pregnancy; Pregnenolone; Progesterone; Sulfates; Umbilical Cord | 1970 |
Deuterium labelled steroid hormones: syntheses and application in quantitation and endocrinology.
Topics: Androstenedione; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Deuterium; Estradiol; Estriol; Estrogens; Estrone; Ethinyl Estradiol; Female; Gas Chromatography-Mass Spectrometry; Glucuronates; Gonadal Steroid Hormones; Humans; Hydroxytestosterones; Isotope Labeling; Male; Pregnancy; Pregnanediones; Pregnenolone; Progesterone; Progestins; Testosterone | 1981 |
The hypothalamic-pituitary-adrenocortical system and sleep in man.
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Circadian Rhythm; Corticotropin-Releasing Hormone; Cushing Syndrome; Dehydroepiandrosterone; Electroencephalography; Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Molecular Sequence Data; Neuroimmunomodulation; Pituitary-Adrenal System; Pregnenolone; Rats; Sleep; Sleep Stages | 1995 |
Cytochrome P450 in the brain: neuroendocrine functions.
Topics: Animals; Brain; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Humans; Neurosecretory Systems; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids | 1995 |
Biosynthesis and assay of neurosteroids in rats and mice: functional correlates.
Topics: Adrenalectomy; Aggression; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Dihydrotestosterone; Female; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Lactation; Male; Memory; Mice; Orchiectomy; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1995 |
An abbreviated account of some aspects of the biochemistry of DHEA, 1934-1995.
Topics: Animals; Cholesterol; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; History, 20th Century; Humans; Pregnenolone | 1995 |
Dehydroepiandrosterone (DHEA) is a neuroactive neurosteroid.
Topics: Acyltransferases; Adrenal Glands; Animals; Behavior, Animal; Brain; Cholesterol; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Ethanol; Female; Haplorhini; Humans; Hydroxysteroid Dehydrogenases; Male; Mice; Pregnenolone; Rats; Sensory Receptor Cells; Sexual Behavior, Animal; Steroid Hydroxylases; Stress, Physiological; Sulfatases; Sulfotransferases; Synaptosomes | 1995 |
[Steroid modulation of GABA(A) receptors].
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; GABA Modulators; Lipid Metabolism; Pregnenolone; Proteins; Receptors, GABA-A; Steroids | 1995 |
Novel microbial transformations of steroids.
Topics: Androstenedione; Biotransformation; Dehydroepiandrosterone; Estrone; Moraxella; Mucor; Pregnenolone; Progesterone; Steroids | 1996 |
Neurosteroids: a role in aging? New functions in the central and peripheral nervous systems.
Topics: Aging; Animals; Central Nervous System; Dehydroepiandrosterone; Peripheral Nervous System; Pregnenolone | 1997 |
Neurosteroids: a novel function of the brain.
Topics: Animals; Brain; Dehydroepiandrosterone; Humans; Memory; Myelin Sheath; Pregnenolone; Progesterone; Receptors, GABA-A; Steroids | 1998 |
Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives.
Topics: Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Humans; Neuroprotective Agents; Neurosecretory Systems; Pregnanolone; Pregnenolone; Progesterone; Steroids | 1999 |
[Neurosteroids: behavioral aspects and physiological implications].
Topics: Animals; Brain; Cognition; Dehydroepiandrosterone; Female; Male; Maze Learning; Mice; Pregnenolone; Rats; Steroids | 1999 |
'New' active steroids and an unforeseen mechanism of action.
Topics: Animals; Dehydroepiandrosterone; Humans; Microtubule-Associated Proteins; Microtubules; Neurons; Pregnenolone; Receptors, Neurotransmitter; Sulfates; Tubulin | 2000 |
[Neurosteroids].
Topics: Animals; Brain; Dehydroepiandrosterone; Humans; Memory; Pregnenolone; Receptors, GABA-A; Stress, Physiological | 1997 |
[Neurosteroids, their role in brain physiology: neurotrophicity, memory, aging...].
Topics: Animals; Dehydroepiandrosterone; Humans; Neuroglia; Neurons; Pregnenolone; Progesterone | 2001 |
Neurosteroids: beginning of the story.
Topics: Animals; Dehydroepiandrosterone; Humans; Nervous System Physiological Phenomena; Pregnenolone; Receptors, Steroid | 2001 |
Neurosteroid 7-hydroxylation products in the brain.
Topics: Animals; Brain; Dehydroepiandrosterone; Humans; Hydroxylation; Pregnenolone | 2001 |
Neurosteroid analysis.
Topics: Animals; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Humans; Pregnenolone; Radioimmunoassay | 2001 |
Role of pregnenolone, dehydroepiandrosterone and their sulfate esters on learning and memory in cognitive aging.
Topics: Aging; Animals; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hippocampus; Humans; Learning; Memory; Pregnenolone; Rats; Reproducibility of Results | 2001 |
Anti-aging products, Part II. What hormones can and can't do.
Topics: Animals; Dehydroepiandrosterone; Estrogen Replacement Therapy; Estrogens; Female; Growth Hormone; Hormones; Humans; Melatonin; Mice; Pregnenolone; Research; Testosterone; Thymus Hormones | 2001 |
Hippocampal cytochrome P450s synthesize brain neurosteroids which are paracrine neuromodulators of synaptic signal transduction.
Topics: Animals; Aromatase; Cells, Cultured; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Hippocampus; Neurotransmitter Agents; Pregnenolone; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Signal Transduction; Steroid 17-alpha-Hydroxylase; Testosterone | 2003 |
MULTIGLANDULAR ASPECTS OF THE STEIN-LEVENTHAL SYNDROME.
Topics: 17-Ketosteroids; Adrenal Gland Diseases; Androgens; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Hypothalamus; Luteinizing Hormone; Ovary; Pituitary Gland; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Steroids; Testosterone | 1963 |
[Effects of sigma receptor ligands on psychiatric disorders].
Topics: Animals; Dehydroepiandrosterone; Disease Models, Animal; Humans; Learning Disabilities; Ligands; Memory Disorders; Mental Disorders; Pregnenolone; Progesterone; Receptors, sigma; Sigma-1 Receptor; Stress, Psychological; Substance-Related Disorders | 2003 |
The hormonal fountains of youth: myth or reality?
Topics: Aging; Animals; Dehydroepiandrosterone; Estrogens; Female; Growth Hormone; Hormone Replacement Therapy; Humans; Male; Melatonin; Mythology; Pregnenolone; Rejuvenation; Testosterone; Vitamin D | 2005 |
Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection.
Topics: Amino Acid Sequence; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Molecular Sequence Data; Neuroprotective Agents; Neurotransmitter Agents; Pregnenolone; Progesterone; Receptors, sigma; Sigma-1 Receptor; Steroids | 2006 |
Neurosteroid regulation of central nervous system development.
Topics: Animals; Central Nervous System; Dehydroepiandrosterone; Humans; Pregnanolone; Pregnenolone; Progesterone; Steroids; Synaptic Transmission | 2007 |
Pregnenolone, dehydroepiandrosterone, and schizophrenia: alterations and clinical trials.
Topics: Adjuvants, Immunologic; Animals; Antipsychotic Agents; Central Nervous System; Clinical Trials as Topic; Dehydroepiandrosterone; Humans; Neuroprotective Agents; Pregnenolone; Receptors, Neurotransmitter; Schizophrenia | 2010 |
Neuroactive steroids in periphery and cerebrospinal fluid.
Topics: Animals; Dehydroepiandrosterone; Humans; Neurotransmitter Agents; Pregnenolone; Rats | 2011 |
Human cytochromes P450 in health and disease.
Topics: Animals; Cholesterol; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Eicosanoids; Enzyme Activation; Evolution, Molecular; Humans; Hydroxylation; Metabolic Diseases; Multigene Family; Oxidation-Reduction; Pregnenolone; Tretinoin; Vitamin D | 2013 |
[Advances in the study of steroidal inhibitors of cytochrome P45017alpha].
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Humans; Male; Molecular Structure; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 2013 |
Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases.
Topics: Animals; Dehydroepiandrosterone; Humans; Nervous System Diseases; Neurogenesis; Neuronal Plasticity; Neurotransmitter Agents; Pregnanolone; Pregnenolone | 2018 |
8 trial(s) available for dehydroepiandrosterone and pregnenolone
| Article | Year |
|---|---|
Secretion of steroid sulfates from human testis and their response to a single intramuscular injection of 5000 IU hCG.
Topics: Adult; Aged; Androstenediol; Androstenediols; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Middle Aged; Pregnenolone; Testis; Testosterone; Veins | 1981 |
Effects of antidepressant treatment on neuroactive steroids in major depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Dehydroepiandrosterone; Depressive Disorder; Female; Fluoxetine; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA; Steroids; Treatment Outcome | 1998 |
Aspirin inhibits androgen response to chorionic gonadotropin in humans.
Topics: Administration, Oral; Adult; Androgens; Androstenedione; Aspirin; Chorionic Gonadotropin; Cyclooxygenase Inhibitors; Dehydroepiandrosterone; Dinoprostone; Estradiol; Humans; Male; Pregnenolone; Progesterone; Single-Blind Method; Testis; Testosterone | 1999 |
Analysis of neurosteroid levels in attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Male; Neurotransmitter Agents; Pregnenolone; Psychiatric Status Rating Scales; Steroids | 2001 |
Adrenocortical hyperresponsiveness to corticotropin in polycystic ovary syndrome patients with adrenal androgen excess.
Topics: 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperandrogenism; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Prospective Studies; Steroid 17-alpha-Hydroxylase; Testosterone | 2004 |
Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial.
Topics: Adolescent; Adult; Antipsychotic Agents; Attention; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Memory, Short-Term; Middle Aged; Neurotransmitter Agents; Pregnenolone; Psychotic Disorders; Schizophrenia; Severity of Illness Index | 2010 |
A history of depression in women is associated with an altered GABAergic neuroactive steroid profile.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Double-Blind Method; Female; Humans; Hydrocortisone; Neurotransmitter Agents; Pregnenolone; Progesterone | 2012 |
DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.
Topics: Androsterone; Antidepressive Agents; Cross-Over Studies; Dehydroepiandrosterone; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Sex Factors; Treatment Outcome | 2015 |
820 other study(ies) available for dehydroepiandrosterone and pregnenolone
| Article | Year |
|---|---|
QSAR's from similarity matrices. Technique validation and application in the comparison of different similarity evaluation methods.
Topics: Carbolines; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Imidazoles; Indoles; Molecular Structure; Pyridines; Structure-Activity Relationship | 1993 |
Structure-activity relationships from molecular similarity matrices.
Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin | 1993 |
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone | 1996 |
Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices.
Topics: Drug Design; Least-Squares Analysis; Molecular Conformation; Steroids; Structure-Activity Relationship; Transcortin | 1998 |
GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors.
Topics: Butyrophenones; Enzyme Inhibitors; Glucose; Models, Molecular; Phosphorylases; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Software; Steroids; Transcortin | 2000 |
Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique.
Topics: Acetates; Alcohols; Algorithms; Cholinergic Agents; Hydrocarbons, Acyclic; Hydrocarbons, Aromatic; Ketones; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Receptor, Muscarinic M2; Receptors, Muscarinic; Steroids; Transcortin | 2003 |
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts | 2003 |
Comparative molecular active site analysis (CoMASA). 1. An approach to rapid evaluation of 3D QSAR.
Topics: Binding Sites; Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Steroids | 2004 |
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids | 2008 |
To determine the cytotoxicity of chlorambucil and one of its nitro-derivatives, conjugated to prasterone and pregnenolone, towards eight human cancer cell-lines.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chlorambucil; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Esters; Humans; Inhibitory Concentration 50; Neoplasms; Nitro Compounds; Pregnenolone | 2009 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Novel steroid inhibitors of glucose 6-phosphate dehydrogenase.
Topics: Antineoplastic Agents; Cell Survival; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; HEK293 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pregnanes; Structure-Activity Relationship | 2012 |
Simultaneous comparison of delta 5-3beta-hydroxysteroid levels in the fetoplacental circulation of normal pregnancy in labor and not in labor.
Topics: Blood; Dehydroepiandrosterone; Female; Fetal Blood; Humans; Hydrogen-Ion Concentration; Labor, Obstetric; Placenta; Pregnancy; Pregnenolone; Umbilical Arteries; Umbilical Veins | 1976 |
Steroid metabolism in the gonads of a patient with testicular feminization. I. Metabolism of cholesterol, pregnenolone, progesterone and dehydroepiandrosterone in vitro.
Topics: Adolescent; Androgen-Insensitivity Syndrome; Cholesterol; Cryptorchidism; Dehydroepiandrosterone; Humans; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis | 1975 |
Steroid sulfatase in brain: comparison of sulfohydrolase activities for various steroid sulfates in normal and pathological brains, including the various forms of metachromatic leukodystrophy.
Topics: Aging; Animals; Arylsulfatases; Brain; Cholesterol; Dehydroepiandrosterone; Detergents; Estrone; Female; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Kinetics; Leukodystrophy, Metachromatic; Male; Mutation; Neurologic Manifestations; Pregnenolone; Rats; Steroids; Sulfatases; Testosterone | 1976 |
In vitro testosterone synthesis by testicular tissue of old mouse: the metabolism of 3beta-hydroxy-5-ene steroids.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Androgens; Androstenediols; Androstenedione; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Mice; Mice, Inbred C57BL; NADP; Pregnenolone; Progesterone; Testis; Testosterone | 1977 |
3beta-Hydroxysteroid dehydrogenase activity in human fetal membranes.
Topics: 3-Hydroxysteroid Dehydrogenases; Amnion; Chorion; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Microsomes; NAD; NADP; Placenta; Pregnancy; Pregnenolone; Subcellular Fractions; Substrate Specificity | 1978 |
Studies of the human fetal adrenal gland--properties of 17alpha-hydroxylase and C17-C20 lyase in the biosynthesis of dehydroepiandrosterone from pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrogen-Ion Concentration; Lyases; Microsomes; NADP; Oxidoreductases; Pregnancy; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Subcellular Fractions | 1978 |
Steroid specificity of human placental 5-ene-3 beta-hydroxysteroid oxidoreductase.
Topics: 3-Hydroxysteroid Dehydrogenases; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrogen-Ion Concentration; Hydroxysteroids; Ketosteroids; NAD; Placenta; Pregnancy; Pregnenolone; Substrate Specificity | 1979 |
Unconjugated steroids in the human endometrium.
Topics: Adult; Dehydroepiandrosterone; Endometrium; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Menstruation; Pregnenolone; Progesterone; Testosterone | 1975 |
Androgen formation from pregnenolone sulfate by fetal, neonatal, prepubertal and adult human testes.
Topics: Adult; Age Factors; Androstenedione; Carbon Radioisotopes; Child; Dehydroepiandrosterone; Fetus; Humans; Infant; Infant, Newborn; Male; Middle Aged; Pregnenolone; Testis; Testosterone; Tritium | 1975 |
Evidence for the existence of a single 3 beta-hydroxysteroid dehydrogenase/delta-5,4-3-oxosteroid isomerase complex in the human adrenal gland.
Topics: Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Kinetics; Multienzyme Complexes; Pregnenolone; Progesterone | 1975 |
Cutaneous hydroxystereoid dehydrogenases and rat-hair cycle.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Cytoplasm; Cytoplasmic Granules; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Hair; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Rats; Sebaceous Glands; Skin; Testosterone | 1975 |
Alternative pathways of steroid biosynthesis in gonads and hepatopancreas of Aplysia depilans.
Topics: Androstenedione; Animals; Cholesterol; Dehydroepiandrosterone; Desmosterol; Digestive System; Gonads; Hydrocortisone; Hydroxyprogesterones; Mevalonic Acid; Mollusca; Organ Specificity; Pregnenolone; Progesterone; Steroids; Testosterone | 1975 |
Metabolic clearance rate, production rate and mammary uptake of progesterone in the goat.
Topics: Androstenedione; Animals; Blood Flow Velocity; Dehydroepiandrosterone; Estradiol; Estrone; Estrus; Female; Goats; Hydrocortisone; In Vitro Techniques; Kinetics; Lymph; Mammary Glands, Animal; Metabolic Clearance Rate; Milk; Pregnancy; Pregnenolone; Progesterone | 1975 |
Conversion of androstenolone to pregnenolone.
Topics: Dehydroepiandrosterone; Methods; Pregnenolone | 1975 |
Foetal and maternal plasma levels of steroid sulphates in human pregnancy at term.
Topics: Androstenes; Androsterone; Dehydroepiandrosterone; Estriol; Female; Fetal Blood; Fetus; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, Third; Pregnanediol; Pregnanes; Pregnenolone; Progesterone | 1975 |
Inhibition of growth and cellular aggregation of Dictyostelium discoideum by steroid compounds.
Topics: Agglutination; Androstenes; Cell Aggregation; Cell Differentiation; Cell Division; Cell Membrane; Dehydroepiandrosterone; Dictyostelium; Dinitrophenols; Edetic Acid; Epinephrine; Estradiol; Estranes; Myxomycetes; Norsteroids; Oxygen Consumption; Pregnanes; Pregnenolone; Progesterone; Prostaglandins; Testosterone | 1975 |
Indices of gonadal function in the human male. I. Plasma levels of unconjugated steroids and gonadotrophins under normal and pathological conditions.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Infertility, Male; Luteinizing Hormone; Male; Middle Aged; Oligospermia; Pregnenolone; Progesterone; Radioimmunoassay; Spermatozoa; Testosterone | 1975 |
Indices of gonadal function in the human male. II. Seminal plasma levels of steroids in normal and pathological conditions.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Gonadal Steroid Hormones; Humans; Hydrolysis; Infertility, Male; Male; Middle Aged; Oligospermia; Pregnenolone; Radioimmunoassay; Semen; Testosterone | 1975 |
Concentration of unconjugated adrenogenic hormones and their precursors in normal and polycystic ovaries.
Topics: 17-Ketosteroids; Adolescent; Adult; Androgens; Androstenedione; Chromatography, Gas; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydroxysteroid Dehydrogenases; Middle Aged; Ovarian Diseases; Ovary; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Testosterone | 1975 |
[Steroid metabolism in primates. XVI. Secretion of corticosteroids in the baboon Papio hamadryas during chronic administration of sodium chloride].
Topics: Adrenal Cortex Hormones; Aldosterone; Androstenols; Animals; Corticosterone; Cortisone; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Papio; Pregnenolone; Progesterone; Sodium Chloride; Time Factors | 1975 |
Steroid entry into rete testis fluid and the blood-testis barrier.
Topics: Androgens; Androstenedione; Animals; Blood-Testis Barrier; Cholesterol; Dehydroepiandrosterone; Estrogens; Hormones; Male; Pregnenes; Pregnenolone; Progesterone; Rats; Rete Testis; Sheep; Testis; Testosterone | 1975 |
Proceedings: Steroid metabolism by normal and tumour-bearing adrenals of BALB/c mice.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstenediols; Animals; Castration; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Pregnenolone; Testosterone | 1975 |
Studies of in vitro steroid metabolism by testis tissue from 'complete' and 'incomplete' forms of testicular feminization.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstane-3,17-diol; Androstenediols; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Male; Pregnanolone; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Steroid metabolism of foetal tissues. I. Metabolism of pregnenolone-4-14C by human foetal ovaries.
Topics: 17-alpha-Hydroxypregnenolone; Age Factors; Androstenedione; Dehydroepiandrosterone; Estradiol; Estrone; Female; Fetus; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Ovarian Cysts; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Steroids in umbilical cord plasma from normal term deliveries.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Dehydroepiandrosterone; Estetrol; Estriol; Female; Fetal Blood; Humans; Hydroxyprogesterones; Male; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Synthesis of dehydroepiandrosterone and dehydroepiandrosterone sulphate by the human adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Corticosterone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Sulfates | 1975 |
Biotransformation of pregnenolone - 7alpha-3H, progesterone - 7alpha-3H and dehydroepiandrosterone - 7alpha-3H by porcine fetal and maternal adrenal homogenate preparations.
Topics: Adrenal Glands; Animals; Biotransformation; Dehydroepiandrosterone; Female; Fetus; Gestational Age; In Vitro Techniques; Pregnancy; Pregnancy, Animal; Pregnenolone; Progesterone; Swine | 1975 |
Method for the quantitation of steroids in umbilical cord plasma.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Arylsulfatases; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estriol; Fetal Blood; Humans; Hydrolysis; Infant, Newborn; Ketosteroids; Pregnanediol; Pregnenolone; Progesterone; Steroids | 1975 |
Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Corpus Luteum; Cricetinae; Dehydroepiandrosterone; Female; Granulosa Cells; Humans; Hydroxysteroid Dehydrogenases; Mice; Ovary; Pregnenolone; Rats; Theca Cells | 1975 |
Hormonal imbalance in breast cancer.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Androstenedione; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Female; Humans; Hydroxysteroid Dehydrogenases; Lyases; Neoplasm Metastasis; Pregnenolone; Progesterone; Steroid Isomerases | 1975 |
Peripheral steroid levels in a patient with virilizing adrenal adenoma.
Topics: 17-alpha-Hydroxypregnenolone; Adenoma; Adrenal Gland Neoplasms; Adult; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids; Testosterone; Virilism | 1975 |
In vitro steroid metabolic studies in testicular 17 beta-reduction deficiency.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Estrone; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Male; Oxidation-Reduction; Pregnenolone; Testis; Testosterone | 1975 |
Studies on the pattern of circulating steroids in the normal menstrual cycle. I. Simultaneous assays of progesterone, pregnenolone, dehydroepiandrosterone, testosterone, dihydrotestosterone, androstenedione, oestradiol and oestrone.
Topics: Adult; Androstanes; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrenes; Estrone; Female; Humans; Luteinizing Hormone; Menstruation; Pregnenes; Pregnenolone; Progesterone; Testosterone; Time Factors | 1976 |
Pathways of testosterone synthesis in decapsulated testes of mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Lanosterol; Leydig Cells; Male; Mice; Pregnenolone; Progesterone; Squalene; Stimulation, Chemical; Testis; Testosterone | 1976 |
Steroidogenesis in rat leydig cells: changes in activity of 5-ane and 5-ene 3beta-hydroxysteroid dehydrogenases during sexual maturation.
Topics: Androgens; Androstane-3,17-diol; Androstanes; Animals; Cell Separation; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Kinetics; Leydig Cells; Male; Microsomes; Pregnenolone; Rats; Sexual Maturation; Structure-Activity Relationship; Testis | 1976 |
In vitro steroidogenesis in porcine corpora lutea.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Progestins; Swine; Testosterone | 1976 |
[A morphohistochemical study of the embryotropic action of steroids with androgenic properties].
Topics: Abnormalities, Drug-Induced; Androgens; Animals; Dehydroepiandrosterone; Female; Histocytochemistry; Methyltestosterone; Nucleic Acids; Pregnancy; Pregnenolone; Proteins; Rats | 1975 |
Hormonal changes during the menstrual cycle of the baboon (Papio hamadryas).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Adrenal Cortex Hormones; Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Female; Haplorhini; Humans; Hydroxyprogesterones; Menstruation; Papio; Pregnenolone; Progesterone; Progestins; Species Specificity; Testosterone | 1976 |
Plasma levels of unconjugated steroids in male baboons (Papio hamadryas) and rhesus monkeys (Macaca mulatta).
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; Haplorhini; Humans; Hydroxyprogesterones; Macaca; Macaca mulatta; Male; Middle Aged; Papio; Pregnenolone; Radioimmunoassay; Species Specificity; Testosterone | 1976 |
A mathematical analysis of the substrate effect observed in 3beta-hydroxysteroid dehydrogenase reactions of rat testicular microsomes.
Topics: Animals; Binding Sites; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Kinetics; Male; Microsomes; Models, Chemical; Pregnenolone; Progesterone Reductase; Protein Binding; Rats; Testis | 1976 |
Ovarian and adrenal contributions to peripheral steroid levels in postmenopausal women.
Topics: Adrenal Cortex Hormones; Aged; Androgens; Androstenediols; Androstenedione; Dehydroepiandrosterone; Dexamethasone; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Menopause; Middle Aged; Pregnenolone; Progesterone; Testosterone | 1976 |
Steroid conjugates in human seminal plasma.
Topics: Adult; Dehydroepiandrosterone; Dihydrotestosterone; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Pregnenolone; Radioimmunoassay; Semen; Sulfates; Testosterone | 1976 |
Endocrine effects of vasectomy.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Luteinizing Hormone; Male; Middle Aged; Pregnenolone; Semen; Testosterone; Time Factors; Vasectomy | 1976 |
Steroid interconversions by metastatic deposits of a human bronchogenic carcinoma.
Topics: Adrenal Cortex Hormones; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Carcinoma, Bronchogenic; Dehydroepiandrosterone; Dihydrotestosterone; Humans; In Vitro Techniques; Lung Neoplasms; Lymphatic Metastasis; Male; Neck; Pregnenolone; Progesterone; Testosterone | 1976 |
Biogenesis of steroid hormones by human mammary gland in vivo and in vitro.
Topics: Androstenedione; Breast Neoplasms; Cyanoketone; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Pregnenolone; Progesterone | 1976 |
Importance of controlled liquefaction periods for valid steroid assays in human seminal plasma.
Topics: Adolescent; Adult; Dehydroepiandrosterone; Estradiol; Freezing; Hormones; Humans; Hydrolysis; Male; Pregnenolone; Semen; Specimen Handling; Temperature; Testosterone | 1976 |
Steroid biosynthesis by the ovary of the European eel, Anguilla anguilla L., at the silver stage.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Androsterone; Animals; Dehydroepiandrosterone; Eels; Female; Hydroxyprogesterones; Kinetics; Metyrapone; Ovary; Pregnenes; Pregnenolone; Progesterone; Testosterone | 1976 |
The measurement of 3beta-hydroxysteroid dehydrogenase in ovaries of fowls (Gallus domesticus).
Topics: Animals; Chickens; Dehydroepiandrosterone; Dexamethasone; Female; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; Organ Size; Ovary; Pregnenolone; Sexual Maturation | 1976 |
Steroid metabolism by fetal and neonatal rat reproductive tracts.
Topics: Androstane-3,17-diol; Androstanes; Animals; Dehydroepiandrosterone; Female; Fetus; Genitalia; Male; Pregnancy; Pregnenolone; Progesterone; Rats; Sulfatases | 1976 |
Endocrine effects of masturbation in men.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Hormones; Humans; Hydrocortisone; Luteinizing Hormone; Male; Masturbation; Pregnenolone; Psychology; Radioimmunoassay; Semen; Testosterone; Time Factors | 1976 |
Cyanoketone-induced inhibition of adrenal 3beta-hydroxy-delta5-steroid oxidoreductase activity in female and male rats in vitro.
Topics: Adrenal Glands; Androstenedione; Androstenols; Androsterone; Animals; Cyanoketone; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; Male; Pregnanediones; Pregnenolone; Progesterone; Rats; Sex Factors | 1976 |
Stimulation of adrogen biosynthesis in rat fetal testes in vitro by gonadotropins.
Topics: Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Luteinizing Hormone; Male; Pregnancy; Pregnenolone; Progesterone; Rats; Testis; Testosterone | 1977 |
Adrenal function in breast cancer: the metabolism of pregnenolone in breast cancer patients.
Topics: Adrenal Cortex Function Tests; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Pregnenolone; Radioisotopes | 1976 |
Steroid hormone formation in human ovarian follicles in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Ovary; Pregnenolone; Progesterone; Progestins; Testosterone | 1976 |
Endocrinology of the blastocyst and its role in the establishment of pregnancy.
Topics: Androstenedione; Animals; Blastocyst; Corpus Luteum; Dehydroepiandrosterone; Endometrium; Estradiol; Estradiol Dehydrogenases; Estrone; Extraembryonic Membranes; Female; Models, Biological; Myometrium; Pregnancy; Pregnenolone; Progesterone; Sulfatases; Swine; Temperature; Time Factors | 1976 |
Studies on the pattern of circulating steroids in the normal menstrual cycle. Circadian variation in theperi-ovulatory period.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Circadian Rhythm; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Menstruation; Pregnenolone; Reference Values; Testosterone | 1977 |
[A radioimmunoassay method for simultaneous determination of pregnenolone, pregnenolone sulfate, dehydroepiandrosterone and dehydroepiandrosterone sulfate in human plasma (author's transl)].
Topics: Adult; Dehydroepiandrosterone; Female; Humans; Pregnenolone; Radioimmunoassay; Sulfuric Acids | 1976 |
Can one mix two non-specific antisera and obtain a specific radioimmunoassay?
Topics: Androstenediols; Androsterone; Cross Reactions; Dehydroepiandrosterone; Immune Sera; Kinetics; Ligands; Mathematics; Pregnenolone; Radioimmunoassay; Steroids | 1977 |
5-ene-3beta-hydroxysteroid dehydrogenase of human and bovine adrenocortical endoplasmic reticulum: solubilization and fractionation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Dehydroepiandrosterone; Endoplasmic Reticulum; Humans; Hydroxysteroid Dehydrogenases; Isoelectric Focusing; Molecular Weight; Pregnenolone | 1977 |
Selective inhibition of glutathione S-transferases by 17 beta-estradiol disulfate.
Topics: Dehydroepiandrosterone; Estradiol; Glutathione; Glutathione Transferase; Hydrocortisone; Kinetics; Pregnenolone; Sulfates | 1977 |
Changes in steroidogenesis by isolated rabbit ovarian follicles in vitro during the preovulatory interval with emphasis on active androgen production.
Topics: 20-alpha-Dihydroprogesterone; Acetates; Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Rabbits; Testosterone | 1977 |
Concentration of steroid hormones and androgen binding protein (ABP) in rabbit efferent duct fluid.
Topics: Androgens; Androstenedione; Animals; Carrier Proteins; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Hormones; Ligation; Male; Pregnenolone; Progesterone; Semen; Testis; Testosterone | 1975 |
Studies on the reproductive cycle on the female cobra, Naja naja. II. In vitro ovarian steroid synthesis.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Kinetics; Luteinizing Hormone; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Reproduction; Snakes; Steroids; Testosterone | 1977 |
Steroid metabolism by mouse preimplantation embryos in vitro.
Topics: Animals; Dehydroepiandrosterone; Embryo, Mammalian; Embryonic Development; Female; In Vitro Techniques; Mice; Pregnancy; Pregnenolone; Progesterone; Steroids | 1977 |
Determination of seven unconjugated steroids in the blood and seminal plasma of the fertile male rabbit.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; Male; Pregnenolone; Rabbits; Radioimmunoassay; Semen; Testosterone | 1977 |
Age dependence of testosterone precursors in plasma of normal adult males.
Topics: Adult; Age Factors; Aged; Androstenediol; Androstenedione; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Humans; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Steroids; Testosterone | 1977 |
Interrelations between plasma levels of biologically active LH and ovarian and adrenal steroids in the normal menstrual cycle.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Circadian Rhythm; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Menstruation; Pregnenolone; Progesterone; Radioimmunoassay | 1977 |
Simultaneous determination of the sulphates of dehydroepiandrosterone and pregnenolone in plasma by radioimmunoassay following a rapid solvolysis.
Topics: Dehydroepiandrosterone; Female; Humans; Menstruation; Pregnenolone; Radioimmunoassay; Solubility; Sulfuric Acids | 1977 |
Species differences in steroidogenesis following the in vitro incubation of decapsulated testes.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Gonadal Steroid Hormones; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Rabbits; Rats; Species Specificity; Stimulation, Chemical; Testis; Testosterone | 1977 |
Steroid sulfatase activity in human fetal membranes.
Topics: Amnion; Chorion; Dehydroepiandrosterone; Extraembryonic Membranes; Female; Humans; Microsomes; Oxidoreductases; Pregnancy; Pregnenolone; Steroid Isomerases; Steroids; Sulfatases | 1977 |
Periovulatory steroid concentrations in HCG-treated rabbits.
Topics: 20-alpha-Dihydroprogesterone; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Estrogens; Female; Ovary; Ovulation; Pregnenolone; Progesterone; Rabbits; Steroids | 1978 |
Histochemical distribution of delta5-3beta- and 17beta-hydroxysteroid dehydrogenases in hamster trophoblast.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Cricetinae; Dehydroepiandrosterone; Estradiol; Female; Histocytochemistry; Pregnancy; Pregnenolone; Testosterone; Trophoblasts | 1977 |
Ovarian steroidogenesis studied by mass fragmentography.
Topics: Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gas Chromatography-Mass Spectrometry; Gonadal Steroid Hormones; Humans; Organ Culture Techniques; Ovary; Pregnenolone; Progesterone; Progestins; Sheep; Testosterone | 1977 |
Testicular steroidogenesis in the mature and immature baboon Papio anubis.
Topics: 20-alpha-Dihydroprogesterone; Androgens; Androstane-3,17-diol; Androstenedione; Animals; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Papio; Pregnenolone; Progesterone; Sexual Maturation; Testis; Testosterone | 1977 |
Substrate specificity for androgen biosynthesis in the primate testis.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Callitrichinae; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Substrate Specificity; Testis; Testosterone | 1978 |
[Simultaneous determination of pregnenolone, 17 alpha-hydroxypregnenolone and dehydroepiandrosterone].
Topics: 17-alpha-Hydroxypregnenolone; Dehydroepiandrosterone; Female; Humans; Infant, Newborn; Pregnancy; Pregnenolone; Radioimmunoassay | 1978 |
Effect of oral contraceptives on plasma androgenic steroids and their precursors.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androstenedione; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1978 |
Androgen, estrogen, and progesterone by a lipid cell tumor of theovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovarian Neoplasms; Ovary; Pregnenolone; Progestins; Testosterone; Veins; Virilism | 1978 |
The steroid profile of a virilizing ovarian tumor.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Female; Granulosa Cell Tumor; Hormones; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Neoplasms, Gonadal Tissue; Ovarian Neoplasms; Pregnenolone; Sertoli Cell Tumor; Testosterone; Virilism | 1978 |
Testicular steroidogenesis in the baboon Papio anubis.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1978 |
Steroid metabolism in testis tissue: the metabolism of pregnenolone, pregnenolone sulfate, dehydroepiandrosterone and dehydroepiandrosterone sulfate in human and boar testes in vitro.
Topics: Animals; Chromatography, Gas; Dehydroepiandrosterone; Humans; Male; Mass Spectrometry; Pregnenolone; Species Specificity; Sulfuric Acid Esters; Swine; Testis | 1978 |
Biologically active luteinizing hormone (LH) in plasma. III. Validation of the in vitro bioassay when applied to male plasma and the possible role of steroidal precursors.
Topics: Adsorption; Androstenedione; Animals; Biological Assay; Charcoal; Dehydroepiandrosterone; Ether; Female; Humans; Luteinizing Hormone; Male; Mice; Pregnenolone; Testis; Testosterone | 1979 |
Steroids in the rete testis fluid of fertile male rabbits.
Topics: Androgens; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Male; Pregnenolone; Rabbits; Rete Testis; Testis; Testosterone | 1979 |
Interrelationships of circulating maternal steroid concentrations in third trimester pregnancies. III. Effect of intravenous cortisol infusion on maternal concentrations of estriol, 16 alpha-hydroxyprogesterone, 17 alpha-hydroxyprogesterone, progesterone,
Topics: 20-alpha-Dihydroprogesterone; Adrenal Cortex Hormones; Adult; Dehydroepiandrosterone; Estriol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnancy; Pregnancy Trimester, Third; Pregnenolone; Progesterone | 1979 |
Serum steroids and pituitary hormones in infants with particular reference to testicular activity.
Topics: Androgens; Androstenedione; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Female; Gonadotropins, Pituitary; Humans; Infant; Male; Pregnenolone; Progesterone; Progestins; Testis; Testosterone | 1979 |
Histochemical study of ovarian hydroxysteroid dehydrogenase activity during normal pseudopregnancy in the rat.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Dehydroepiandrosterone; Dihydrolipoamide Dehydrogenase; Female; Granulosa Cells; Histocytochemistry; Ovarian Follicle; Ovary; Pregnenolone; Pseudopregnancy; Rats; Theca Cells | 1979 |
Steroid metabolism in vitro by gonadal tissue from a true hermaphrodite.
Topics: Dehydroepiandrosterone; Disorders of Sex Development; Female; Gonads; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Testosterone | 1979 |
Radioimmunoassay of steroids produced by chick embryo gonads cultured in the presence of some exogenous steroid precursors.
Topics: Androstenedione; Animals; Chick Embryo; Dehydroepiandrosterone; Female; Hormones; Kinetics; Male; Organ Culture Techniques; Ovary; Pregnenolone; Radioimmunoassay; Sex Factors; Steroids; Testis | 1979 |
Steroid biosynthetic lesions in gonadotropin-desensitized Leydig cells.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Dehydroepiandrosterone; Hydroxyprogesterones; Leydig Cells; Male; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1979 |
Metabolism of [17-2H]pregnenolone into 5-[17 beta-2H, 17 alpha-18O]androstene-3 beta, 17 alpha-diol and other products by incubation with the microsomal fraction of boar testis under 18O2 atmosphere.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenediol; Androstenediols; Animals; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Male; Microsomes; Oxygen Isotopes; Pregnenolone; Swine; Testis; Time Factors | 1979 |
Metabolism of pregnenolone and progesterone by testicular microsomes of the baboon Papio anubis and the marmoset Saguinus oedipus.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Callitrichinae; Dehydroepiandrosterone; In Vitro Techniques; Male; Microsomes; Papio; Pregnenolone; Progesterone; Testis; Testosterone | 1979 |
Prenatal exposure to testosterone and its precursors influences morphology and later behavioral responsiveness to testosterone of female mice.
Topics: Aggression; Animals; Behavior, Animal; Castration; Dehydroepiandrosterone; Female; Humans; Maternal-Fetal Exchange; Mice; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1979 |
Variations in serum androgens, estrogens, progestins, gonadotropins and prolactin levels in male rats from prepubertal to advanced age.
Topics: Aging; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Rats; Testosterone | 1979 |
Metabolism of pregnenolone by human breast cancer. Evidence for 17 alpha-hydroxylase and 17,20-lyase.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aldehyde-Lyases; Androstenedione; Breast Neoplasms; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydroxyprogesterones; Menopause; Middle Aged; Pregnenolone; Progesterone; Receptors, Estrogen; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1979 |
Microbial introduction of a 16 alpha-hydroxyl function into the steroid nucleus.
Topics: Androstenediol; Androstenedione; Aryl Hydrocarbon Hydroxylases; Dehydroepiandrosterone; Estrone; Hydroxylation; Hydroxysteroids; Pregnenolone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Streptomyces; Substrate Specificity | 1979 |
[In vitro studies of testicular biosynthesis in 4 cases of male pseudohermaphrodism (MPH) due to testicular 17 ketoreductase defect (author's transl)].
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Androstenediols; Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Estrone; Humans; In Vitro Techniques; Male; Pregnenolone; Progesterone; Testis; Testosterone | 1979 |
Plasma levels of gonadotropins, prolactin, thyroxine, and adrenal and gonadal steroids in obese prepubertal girls.
Topics: Adrenal Cortex Hormones; Aging; Child; Dehydroepiandrosterone; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Obesity; Pregnenolone; Progesterone; Prolactin; Sexual Maturation; Thyroxine | 1978 |
Effect of exogenous estrogen on serum pregnenolone, cortisol, and androgens in postmenopausal women.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menopause; Pregnenolone; Statistics as Topic; Testosterone | 1975 |
Control of oestrogen production in human pregnancy: effect of trophic hormones on steroid biosynthesis by the foetal adrenal gland in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Growth Hormone; Humans; In Vitro Techniques; Male; Pituitary Hormones, Anterior; Placental Lactogen; Pregnancy; Pregnenolone; Steroids | 1976 |
Biogenesis of corticosteroids in monolayer cultures of human foetal adrenal cells.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Corticosterone; Dehydroepiandrosterone; Hydrocortisone; Pituitary Gland; Pregnenolone; Progesterone; Time Factors | 1976 |
HCG + ACTH stimulation of in vitro dehydroepiandrosterone production in human fetal adrenals from precursor cholesterol and delta5-pregnenolone.
Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Gestational Age; Humans; In Vitro Techniques; Microsomes; Pregnenolone; Stimulation, Chemical | 1975 |
Proceedings: Regulation of androgen synthesis in the human adrenal gland in vivo and in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Gonadotropin-Releasing Hormone; Humans; Pregnenolone; Thyrotropin-Releasing Hormone | 1975 |
Effects of estrogens on adrenal 3 beta-hydroxysteroid dehydrogenase in ovariectomized women.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenediols; Androstenedione; Castration; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Pregnenolone; Progesterone; Testosterone | 1976 |
The specificity of the 3beta-hydroxysteroid dehydrogenase activity of bovine ovaries toward dehydroepiandrosterone and pregnenolone: evidence for multiple enzymes.
Topics: Animals; Cattle; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; Isoenzymes; Kinetics; Microsomes; NAD; Ovary; Polyethylene Glycols; Pregnenolone; Subcellular Fractions | 1976 |
Male pseudohermaphroditism consistent with 17,20-desmolase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hydroxyprogesterones; Luteinizing Hormone; Lyases; Male; Phenotype; Pregnenolone; Progesterone; Testosterone | 1976 |
Effects of trypsin and phospholipases A2 and C on enzyme organization in testis microsomes.
Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Cytosol; Dehydroepiandrosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Mice; Microsomes; Mitochondria; Phospholipases; Pregnenolone; Progesterone; Receptors, Cell Surface; Steroid Hydroxylases; Testis; Testosterone; Trypsin | 1976 |
Studies on the metabolism of steroid hormones in a virilizing adrenal cortex adenoma.
Topics: Adenoma; Adrenal Cortex Neoplasms; Androstenedione; Child; Chromatography, Gas; Dehydroepiandrosterone; Female; Humans; Pregnenolone; Progesterone; Testosterone | 1978 |
The role of serum lipoproteins in steroidogenesis by the human fetal adrenal cortex.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Blood Proteins; Dehydroepiandrosterone; Humans; Hydrocortisone; Lipoproteins; Organ Culture Techniques; Pregnenolone | 1979 |
The effects of progesterone, pregnenolone, estriol, ACTH and hCG on steroid secretion of cultured human fetal adrenals.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Estriol; Female; Fetus; Humans; Hydrocortisone; Pregnancy; Pregnenolone; Progesterone | 1979 |
Changes throughout puberty in adrenal secretion after ACTH.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Age Factors; Androstenedione; Child; Dehydroepiandrosterone; Dexamethasone; Estradiol; Female; Hormones; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Puberty; Testosterone | 1979 |
Dexamethasone suppressibility of plasma pregnenolone or dehydroepiandrosterone in gonadectomized patients.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pregnenolone; Prostatic Neoplasms | 1979 |
Androgen biosynthesis in experimental cryptorchidism.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cryptorchidism; Dehydroepiandrosterone; Guinea Pigs; Hydroxyprogesterones; Male; Pregnenolone; Testis; Testosterone | 1975 |
Cytochrome P-450(17 alpha,lyase)-mediating pathway of androgen synthesis in bovine adrenocortical cultured cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Enzyme-Linked Immunosorbent Assay; Pregnenolone; Steroid 17-alpha-Hydroxylase | 1992 |
Neurosteroids: pregnenolone in human sciatic nerves.
Topics: Adult; Aged; Aged, 80 and over; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Female; Humans; Male; Mass Spectrometry; Middle Aged; Pregnenolone; Radioimmunoassay; Sciatic Nerve | 1992 |
In vitro formation of testosterone via the delta 5-pathway in the human umbilical cord.
Topics: Chromatography; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Pregnenolone; Testosterone; Umbilical Cord | 1992 |
Kinetic evidence for separate 3 beta-hydroxysteroid dehydrogenase-isomerases in androgen and 16-androstene biosynthetic pathways in the pig testis.
Topics: Androgens; Androstadienes; Androstenedione; Androstenes; Animals; Dehydroepiandrosterone; Isoenzymes; Kinetics; Male; Microsomes; Multienzyme Complexes; Pregnenolone; Progesterone Reductase; Steroid Isomerases; Swine; Testis | 1992 |
Administration of pregnenolone and dehydroepiandrosterone to guinea pigs and rats causes the accumulation of fatty acid esters of pregnenolone and dehydroepiandrosterone in plasma lipoproteins.
Topics: Animals; Chromatography, Gel; Chromatography, Liquid; Dehydroepiandrosterone; Esters; Fatty Acids; Guinea Pigs; Lipoproteins; Lipoproteins, HDL; Male; Metabolic Clearance Rate; Pregnenolone; Rats | 1992 |
Neurosteroid metabolism. 7 alpha-Hydroxylation of dehydroepiandrosterone and pregnenolone by rat brain microsomes.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Animals; Brain; Dehydroepiandrosterone; Estrogens; Hydroxylation; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Pregnenolone; Rats; Rats, Sprague-Dawley; Substrate Specificity | 1992 |
Delta 5-3 beta-hydroxysteroid acyl transferase activity in the rat brain.
Topics: Acyltransferases; Aging; Animals; Brain; Dehydroepiandrosterone; Fatty Acids; Hydrogen-Ion Concentration; Hydrolysis; Male; Microsomes; Pregnenolone; Rats; Rats, Inbred Strains; Substrate Specificity; Testosterone | 1992 |
Memory-enhancing effects in male mice of pregnenolone and steroids metabolically derived from it.
Topics: Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Male; Memory; Mice; Pregnenolone; Steroids; Testosterone | 1992 |
Suppressive effects of dehydroepiandrosterone and 3 beta-methyl-androst-5-en-17-one on attack towards lactating female intruders by castrated male mice. II. Brain neurosteroids.
Topics: Aggression; Androstenes; Animals; Brain; Dehydroepiandrosterone; Female; Lactation; Male; Mice; Orchiectomy; Pregnenolone; Steroids; Testosterone | 1991 |
Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.
Topics: 17-alpha-Hydroxypregnenolone; Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; DNA; Escherichia coli; In Vitro Techniques; Molecular Sequence Data; Pregnenolone; Progesterone; Recombinant Proteins; Spectrum Analysis; Steroid 17-alpha-Hydroxylase | 1991 |
Characterization of the structure-activity relationships of rat types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5 -delta 4 isomerase by site-directed mutagenesis and expression in HeLa cells.
Topics: Amino Acid Sequence; Animals; Autoradiography; Blotting, Western; Chimera; Cloning, Molecular; Dehydroepiandrosterone; DNA; HeLa Cells; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Pregnenolone; Progesterone Reductase; Rats; Steroid Isomerases; Structure-Activity Relationship; Substrate Specificity | 1991 |
Effect of activin A on dehydroepiandrosterone and testosterone secretion by primary immature porcine Leydig cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Activins; Animals; Cells, Cultured; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dihydrotestosterone; Hydroxycholesterols; Inhibins; Leydig Cells; Male; Pregnenolone; Swine; Testosterone | 1991 |
Steroid metabolism in gonads of turtle embryos as a function of the incubation temperature of eggs.
Topics: Androstenedione; Animals; Autoradiography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Gonads; Male; Pregnenolone; Progesterone; Protein Precursors; Steroids; Temperature; Turtles | 1991 |
Steroid sulfatase activities in human leukocytes: biochemical and clinical aspects.
Topics: Arylsulfatases; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrone; Female; Humans; Ichthyosis Vulgaris; Ichthyosis, X-Linked; Leukocytes; Male; Placenta; Pregnenolone; Steryl-Sulfatase; Tritium | 1991 |
Steroidogenesis in interstitial cells and microsomal fraction of immature pig testes.
Topics: 17-alpha-Hydroxypregnenolone; Aminoglutethimide; Androgens; Androstenes; Animals; Bucladesine; Cholera Toxin; Chorionic Gonadotropin; Dehydroepiandrosterone; Male; Microsomes; Pregnenolone; Swine; Testis | 1991 |
Human 3 beta-hydroxysteroid dehydrogenase/delta 5----4isomerase from placenta: expression in nonsteroidogenic cells of a protein that catalyzes the dehydrogenation/isomerization of C21 and C19 steroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Androstenedione; Base Sequence; Dehydroepiandrosterone; DNA; Female; Gene Expression; Humans; Hydroxyprogesterones; Immunoblotting; Isomerases; Microsomes; Molecular Sequence Data; Multienzyme Complexes; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; Steroid Isomerases; Transfection; Tumor Cells, Cultured | 1990 |
Steroid sulfohydrolase in human chorion and decidua: studies using pregnenolone sulfate and dehydroepiandrosterone sulfate as substrate.
Topics: Arylsulfatases; Chorion; Culture Techniques; Decidua; Dehydroepiandrosterone; Estrogens; Estrone; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Labor, Obstetric; Microsomes; Pregnancy; Pregnenolone; Progesterone; Steryl-Sulfatase; Sulfatases; Temperature | 1990 |
Delta 5-3 beta-hydroxysteroid dehydrogenase-isomerase activity in canine pancreas.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pancreas; Pregnenolone; Progesterone | 1990 |
Altered steroidogenic pattern of human granulosa-lutein cells in relation to cumulus cell culture morphology.
Topics: Androstenedione; Cells, Cultured; Corpus Luteum; Dehydroepiandrosterone; Embryo Transfer; Estradiol; Female; Fertilization in Vitro; Granulosa Cells; Humans; Oocytes; Pregnenolone; Progesterone; Testosterone | 1990 |
Circadian-infradian rhythmic variation of brain neurosteroids in the female rat.
Topics: Animals; Brain; Circadian Rhythm; Dehydroepiandrosterone; Female; Lipid Metabolism; Periodicity; Pregnenolone; Rats; Steroids | 1990 |
Interaction of 17 beta-estradiol and progesterone production in human granulosa-luteal cells.
Topics: Androstenediol; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Female; Granulosa Cells; Humans; In Vitro Techniques; Pregnenolone; Progesterone | 1990 |
Characterization of the steroid-metabolizing capacity of the hepatic cytochrome P450IIC5 expressed in COS-1 cells: 3 beta-hydroxysteroid dehydrogenase/delta 5----4 isomerase type activity.
Topics: Animals; Cell Line; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dehydroepiandrosterone; Kinetics; Liver; Multienzyme Complexes; Plasmids; Pregnenolone; Progesterone; Progesterone Reductase; Rabbits; Steroid 21-Hydroxylase; Steroid Isomerases; Substrate Specificity; Transfection | 1990 |
Serum steroid hormone levels in neonates born from the mother with placental sulfatase deficiency.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Dehydroepiandrosterone; Female; Fetal Blood; Gonadal Steroid Hormones; Humans; Hydrocortisone; Infant, Newborn; Male; Placenta; Pregnancy; Pregnenolone; Sulfatases | 1990 |
Steroid fatty acid esters in adrenals and plasma: effects of ACTH.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenediol; Animals; Cattle; Dehydroepiandrosterone; Dogs; Fatty Acids; Guinea Pigs; Humans; Male; Middle Aged; Pregnenolone; Rats; Time Factors | 1990 |
Biosynthetic pathways of testosterone and estradiol-17 beta in slices of the embryonic ovary and testis of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenedione; Animals; Chick Embryo; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Hydroxyprogesterones; Male; Ovary; Pregnenolone; Testis; Testosterone | 1989 |
Partial characterization of steroid sulfohydrolase and steroid sulfotransferase activities in purified porcine Leydig cells.
Topics: Androstenediols; Animals; Arylsulfatases; Chromatography; Chromatography, Gel; Cytosol; Dehydroepiandrosterone; Estrone; Hydrogen-Ion Concentration; Isoelectric Point; Isoenzymes; Kinetics; Leydig Cells; Male; Molecular Weight; Pregnenolone; Steryl-Sulfatase; Sulfatases; Sulfotransferases; Sulfurtransferases; Swine | 1989 |
Regulation of the 3 beta-hydroxysteroid dehydrogenase activity in tissue fragments and microsomes from human term placenta: kinetic analysis and inhibition by steroids.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Binding, Competitive; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Gonadal Steroid Hormones; Humans; Kinetics; Microsomes; Placenta; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1989 |
Pregnenolone, dehydroepiandrosterone, and their sulfate and fatty acid esters in the rat brain.
Topics: Animals; Brain Chemistry; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Esters; Estrus; Fatty Acids; Female; Male; Orchiectomy; Pregnenolone; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
The testes of moles (Talpa europaea) retain a considerable microsomal capacity for androgen synthesis during seasonal regression.
Topics: Androgens; Animals; Dehydroepiandrosterone; Eulipotyphla; Male; Microsomes; Moles; Organ Size; Pregnenolone; Seasons; Testis | 1989 |
On the mechanisms involved in the inhibitory and stimulating actions of transforming growth factor-beta on porcine testicular steroidogenesis: an in vitro study.
Topics: Androgens; Androstenedione; Animals; Dehydroepiandrosterone; In Vitro Techniques; Leydig Cells; Male; Microscopy, Phase-Contrast; Pregnenolone; Swine; Testosterone; Transforming Growth Factors | 1989 |
Changes in steroid pattern following acute and chronic adrenocorticotropin administration in premature adrenarche.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androstenedione; Child; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Pregnenolone; Puberty, Precocious | 1989 |
Co-induction of 17 alpha-hydroxylase and C-17,20-lyase activities in primary cultures of bovine adrenocortical cells in response to ACTH treatment.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Aldehyde-Lyases; Animals; Bucladesine; Cattle; Cells, Cultured; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Kinetics; Microsomes; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1988 |
Basal and HCG-stimulated testosterone production by interstitial cells of the Mongolian gerbil (Meriones unguiculatus)--II. Influence of glucocorticosteroids and steroidal precursors.
Topics: 17-alpha-Hydroxyprogesterone; Animals; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Gerbillinae; Glucocorticoids; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Time Factors | 1986 |
Male pseudohermaphroditism due to multiple defects in steroid-biosynthetic microsomal mixed-function oxidases. A new variant of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Hyperplasia, Congenital; Aldehyde-Lyases; Aldosterone; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Dihydrotestosterone; Disorders of Sex Development; Humans; Hydrocortisone; Infant; Male; Mixed Function Oxygenases; Pregnenolone; Progesterone; Steroid Hydroxylases; Testosterone | 1985 |
Early sex differences in hormonal potentialities of gonads from quail embryos with a sex-linked pigmentation marker: an in vitro radioimmunoassay study.
Topics: Animals; Dehydroepiandrosterone; Embryo, Nonmammalian; Estradiol; Estrone; Eye; Female; Genetic Linkage; Male; Mutation; Ovary; Pigments, Biological; Pregnenolone; Progesterone; Quail; Radioimmunoassay; Sex Differentiation; Testis; Testosterone | 1985 |
Identification of nonecdysteroid steroids in hemolymph of both male and female Astacus leptodactylus (Crustacea) by gas chromatography-mass spectrometry.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cholesterol; Crustacea; Dehydroepiandrosterone; Dihydrotestosterone; Female; Gas Chromatography-Mass Spectrometry; Hemolymph; Hydroxyprogesterones; Hydroxytestosterones; Male; Pregnenolone; Steroids; Testosterone | 1986 |
Steroid metabolism in the seminal vesicles of the African catfish, Clarias gariepinus (Burchell), during the spawning season, under natural conditions, and kept in ponds.
Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Environment; Fishes; Glucuronates; In Vitro Techniques; Male; Pregnenolone; Reproduction; Seminal Vesicles | 1986 |
Effect of trilostan on steroid excretion in man: compensated inhibition of 3 beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Adult; Aldosterone; Androstenediol; Chromatography, Gas; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Glucocorticoids; Humans; Hydrocortisone; Male; Pregnenolone; Renin; Steroids | 1986 |
The effect of dehydroepiandrosterone sulfate on de novo and low-density lipoprotein-stimulated progesterone secretion by human choriocarcinoma JEG-3 cells.
Topics: Cell Line; Cells, Cultured; Choriocarcinoma; Culture Media; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; In Vitro Techniques; Lipoproteins, LDL; Pregnancy; Pregnenolone; Progesterone; Trophoblasts; Uterine Neoplasms | 1986 |
Intratesticular unconjugated steroids in elderly men.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Reference Values; Steroids; Testis; Testosterone | 1986 |
Concentrations of steroid hormones, and of prolactin, in washings of the human uterus during the menstrual cycle.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Gonadal Steroid Hormones; Humans; Menstrual Cycle; Pregnenolone; Prolactin; Proteins; Uterus | 1986 |
Sex steroids and 5-en-3 beta-hydroxysteroids in specific regions of the human brain and cranial nerves.
Topics: Androstenedione; Brain Chemistry; Cranial Nerves; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; Humans; Hydroxysteroids; Pregnenolone; Progesterone; Retina; Testosterone; Tissue Distribution | 1986 |
Blood and tissue steroid levels and their interrelationship in men with pathological conditions of the reproductive organs.
Topics: Adult; Aged; Aged, 80 and over; Arteries; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Epididymis; Genital Diseases, Male; Humans; Male; Middle Aged; Pregnenolone; Steroids; Testis; Testosterone; Vas Deferens; Veins | 1986 |
Biosynthesis of dehydroepiandrosterone by term human fetal chorion in vitro.
Topics: Adult; Chorion; Dehydroepiandrosterone; Female; Humans; Pregnancy; Pregnenolone | 1987 |
[Placental sulfatase deficiency in Japan].
Topics: Adult; Cesarean Section; Dehydroepiandrosterone; Estriol; Estrogens; Female; Humans; Hypogonadism; Ichthyosis; Infant, Newborn; Male; Placenta; Pregnenolone; Sulfatases | 1987 |
Chronobiologic dynamics of delta 5-3 beta-hydroxysteroids and glucocorticoids in rat brain and plasma and human plasma.
Topics: Animals; Brain Chemistry; Circadian Rhythm; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Glucocorticoids; Humans; Hydrocortisone; Hydroxysteroids; Male; Pregnenolone; Rats; Rats, Inbred Strains | 1987 |
The skin of the male African catfish, Clarias gariepinus: a source of steroid glucuronides.
Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Catfishes; Dehydroepiandrosterone; Glucuronates; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Skin; Steroids; Testosterone; Tritium | 1987 |
Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiandrosterone and 17-hydroxyprogesterone in specific regions of human brain.
Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Brain Chemistry; Cross Reactions; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Pregnenolone; Progesterone; Radioimmunoassay; Tissue Distribution | 1987 |
Neuro-steroids: 3 beta-hydroxy-delta 5-derivatives in rat and monkey brain.
Topics: Adrenal Glands; Adrenalectomy; Aggression; Animals; Brain; Castration; Circadian Rhythm; Dehydroepiandrosterone; Dexamethasone; Esters; Fatty Acids; Female; Glucocorticoids; Macaca fascicularis; Male; Mice; Pregnenolone; Rats; Sulfates; Tissue Distribution | 1987 |
Effect of heterosexual olfactory and visual stimulation on 5-en-3 beta-hydroxysteroids and progesterone in the male rat brain.
Topics: Animals; Arousal; Brain Chemistry; Dehydroepiandrosterone; Female; Male; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal; Smell; Visual Perception | 1987 |
Progesterone and estradiol production by normal and preeclamptic placentas.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Humans; In Vitro Techniques; Placenta; Pre-Eclampsia; Pregnancy; Pregnenolone; Progesterone | 1988 |
[Changes in maternal plasma levels of C21 and C19 steroid hormones during pregnancy].
Topics: Dehydroepiandrosterone; Female; Humans; Pregnancy; Pregnenolone; Progesterone; Radioimmunoassay | 1988 |
Endocrine, seminal and peripheral effects of depot medroxyprogesterone acetate and testosterone enanthate in men.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Delayed-Action Preparations; Dihydrotestosterone; Estradiol; Humans; Hydrocortisone; Luteinizing Hormone; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Pregnenolone; Semen; Testosterone | 1988 |
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate | 1988 |
[The role of dehydroepiandrosterone and pregnenolone in the expression of stress behavior towards lactating females in mice].
Topics: Aggression; Animals; Brain Chemistry; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Lactation; Male; Mice; Mice, Inbred Strains; Orchiectomy; Pregnancy; Pregnenolone; Stress, Physiological; Testosterone | 1988 |
Influence of follicular atresia on LH-induced cAMP and steroid synthesis by bovine thecae interna.
Topics: Androstenedione; Animals; Cattle; Chorionic Gonadotropin; Cyclic AMP; Dehydroepiandrosterone; Female; Follicular Atresia; Follicular Phase; Luteinizing Hormone; Pregnenolone; Progesterone; Steroids; Testosterone; Theca Cells | 1985 |
Kinetic studies on the enzymes involved in estrogen biosynthesis and evidence for existence of a single 5-Ene-3beta-hydroxysteroid dehydrogenase complex in the ovary of the freshwater catfish, Clarias batrachus.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Fishes; Kinetics; Ovary; Pregnenolone; Testosterone | 1985 |
Enhanced 17 alpha-hydroxylation of pregnenolone and increased androgen production by rabbit adrenocortical cells stimulated chronically with corticotropin.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxylation; In Vitro Techniques; Male; Pregnenolone; Rabbits; Stimulation, Chemical | 1986 |
Steroidogenic expression of delta 5-3 beta-hydroxy pathway of androgen biosynthesis by human breast carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; Acetyl Coenzyme A; Adult; Aged; Androgens; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cholesterol; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Middle Aged; Models, Chemical; Pregnenolone | 1986 |
[Age-related changes in secretion of adrenocortical steroid hormones in normal healthy men].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Aging; Cosyntropin; Dehydroepiandrosterone; Dexamethasone; Humans; Injections, Intramuscular; Male; Middle Aged; Pregnenolone; Progesterone; Radioimmunoassay | 1986 |
Normal ovarian function in a mild form of late-onset 3 beta-hydroxysteroid dehydrogenase deficiency.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenocorticotropic Hormone; Adult; Age Factors; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Female; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Menstrual Cycle; Ovary; Ovulation; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Prolactin; Testosterone | 1986 |
The role of calmodulin antagonists on steroidogenesis by fetal zone cells of the human fetal adrenal gland.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Bucladesine; Calmodulin; Cells, Cultured; Chlorpromazine; Cyclic AMP; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Embryo, Mammalian; Fetus; Humans; Hydrocortisone; Imidazoles; Kinetics; Pregnenolone; Trifluoperazine | 1987 |
Chronic treatment with corticotropin increases the capacity of rabbit adrenocortical cells to convert pregnenolone into androgens.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Androstenedione; Animals; Cosyntropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; In Vitro Techniques; Kinetics; Pregnenolone; Rabbits; Testosterone | 1987 |
Pattern of plasma levels of cortisol, dehydroepiandrosterone and pregnenolone sulphate in normal subjects and in patients with homozygous familial hypercholesterolaemia during ACTH infusion.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Hyperlipoproteinemia Type II; Male; Pregnenolone | 1986 |
On the existence of receptors to the pheromonal steroid, 5 alpha-androst-16-en-3-one, in porcine nasal epithelium.
Topics: Androstenes; Animals; Cell Membrane; Charcoal; Dehydroepiandrosterone; Epithelium; Female; Hot Temperature; Nasal Mucosa; Olfactory Mucosa; Pregnenolone; Receptors, Androgen; Receptors, Steroid; Swine | 1985 |
Relationship between the structures and steroidogenic functions of the testes of the urohaze-goby (Glossogobius olivaceus).
Topics: 17-alpha-Hydroxyprogesterone; Androstane-3,17-diol; Androstenedione; Animals; Dehydroepiandrosterone; Dihydrotestosterone; Etiocholanolone; Fishes; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone | 1985 |
Kinetic analysis of adrenal 3 beta-hydroxysteroid dehydrogenase activity during human development.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Glands; Adult; Aging; Child; Dehydroepiandrosterone; Female; Humans; Infant; Kinetics; Male; Microsomes; Middle Aged; NAD; Pregnenolone | 1985 |
[Analytical method of delta 5-3 beta OH steroid sulfates using high performance liquid chromatography and immobilized 3beta-hydroxysteroid dehydrogenase in column form].
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Humans; Pregnenolone | 1985 |
The identification, quantification and possible origin of non-polar conjugates in human plasma.
Topics: Acne Vulgaris; Adult; Aged; Androstenediol; Breast Neoplasms; Dehydroepiandrosterone; Female; Hirsutism; Humans; Male; Middle Aged; Pregnancy; Pregnenolone; Steroids | 1985 |
Effect of 5-thio-D-glucose on testosterone biosynthesis in vivo in mice testes.
Topics: Acetates; Acetic Acid; Animals; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Glucose; Hydroxysteroid Dehydrogenases; Male; Mice; Pregnenolone; Progesterone; Sterol Esterase; Testis; Testosterone | 1985 |
Gas chromatographic-mass spectrometric study of metabolites of C21 and C19 steroids in neonatal porcine testicular microsomes.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androstenediol; Androstenols; Animals; Animals, Newborn; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxyprogesterones; Male; Microsomes; Pregnanes; Pregnenolone; Progesterone; Swine; Testis | 1985 |
[Effect of steroids on the formation of progesterone in the fetal membrane].
Topics: Cells, Cultured; Cesarean Section; Dehydroepiandrosterone; Estradiol; Extraembryonic Membranes; Female; Humans; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1985 |
Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man.
Topics: 17-alpha-Hydroxypregnenolone; Anabolic Agents; Androgens; Androstenediol; Androstenedione; Carrier Proteins; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Kinetics; Male; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin; Sports; Testosterone | 1985 |
Steroid hormones in uterine washings and in plasma of gilts between days 9 and 15 after oestrus and between days 9 and 15 after coitus.
Topics: Androstenedione; Animals; Copulation; Dehydroepiandrosterone; Estradiol; Estrone; Estrus; Female; Pregnancy; Pregnenolone; Progesterone; Steroids; Swine; Testosterone; Time Factors; Uterus | 1985 |
Steroid formation in porcine ovarian tissue in vitro. Kinetic studies on the 3beta-hydroxysteroid dehydrogenase.
Topics: Androsterone; Animals; Carbon Isotopes; Chlormadinone Acetate; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kinetics; Ovary; Pregnenolone; Progesterone; Swine | 1970 |
The formation of steroid-BSA antigens via a C-6 -carboxymethyl substituent.
Topics: Acetates; Acylation; Alkylation; Allyl Compounds; Animals; Antigens; Borohydrides; Cattle; Chemical Phenomena; Chemistry; Cross Reactions; Dehydroepiandrosterone; Epitopes; Haptens; Oxidation-Reduction; Pregnenolone; Progesterone; Rabbits; Radioimmunoassay; Serum Albumin, Bovine; Testosterone; Tritium | 1972 |
[Steroid metabolism in primates. XIV. Influence of long-term ovosiston therapy on the secretion of adrenal vein blood steroids in Papio hamadryas].
Topics: Adrenal Glands; Androstenes; Animals; Chlormadinone Acetate; Dehydroepiandrosterone; Female; Haplorhini; Hormones; Mestranol; Papio; Pregnenolone; Progesterone; Time Factors; Veins | 1972 |
Agglutination of spermatozoa by human sera with added steroids.
Topics: Agglutination; Agglutinins; Carbon Radioisotopes; Chlormadinone Acetate; Cholesterol; Corticosterone; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Ethisterone; Female; Humans; Infertility; Male; Norethindrone; Pregnenolone; Progesterone; Spectrophotometry, Ultraviolet; Spermatozoa; Steroids; Testosterone | 1973 |
Metabolism of 3-beta-hydroxy-5-ene steroids by testes of rats acclimatized to a hot environment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acclimatization; Androstanes; Androstenedione; Androstenes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Cryptorchidism; Dehydroepiandrosterone; Hot Temperature; Hydroxyprogesterones; In Vitro Techniques; Male; NADP; Pregnenolone; Rats; Testis; Testosterone; Time Factors; Tissue Extracts | 1973 |
In vitro steroidogenesis in feline testes.
Topics: Androstenedione; Androstenols; Animals; Carbon Radioisotopes; Castration; Cats; Chromatography, Thin Layer; Cytosol; Dehydroepiandrosterone; Hydrocortisone; Hydroxyprogesterones; Male; Microsomes; NAD; NADP; Oxidation-Reduction; Pregnenolone; Progesterone; Testis; Testosterone; Time Factors | 1973 |
In vitro biosynthesis of androgens in canine testes.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Cytosol; Dehydroepiandrosterone; Dogs; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Stimulation, Chemical; Testis; Testosterone; Time Factors | 1973 |
In vitro on an HCG responsive, testosterone secreting adrenal cortical adenoma.
Topics: Acetates; Adenoma; Adenosine Triphosphate; Adrenal Gland Neoplasms; Androstenedione; Carbon Radioisotopes; Chorionic Gonadotropin; Coenzymes; Dehydroepiandrosterone; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Radioimmunoassay; Subcellular Fractions; Testosterone; Tritium | 1973 |
Kinetic studies on the enzymes catalysing the conversion of 17alpha-hydroxyprogesterone and dehydroepiandrosterone to androstenedione in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; NAD; NADP; Oxidoreductases; Pregnenolone; Progesterone | 1974 |
Characteristics of the nuclear and microsomal steroid delta-4-5 alpha-hydrogenase of the rat prostate.
Topics: Androstenedione; Androstenes; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Hydrogen-Ion Concentration; Hydroxyprogesterones; Male; Microsomes; Microsomes, Liver; NADP; Oxidoreductases; Pregnenolone; Progesterone; Prostate; Temperature; Testosterone; Tritium | 1974 |
Steroidogenesis in vitro by the ovarian tissue of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; NAD; NADP; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone; Time Factors; Tritium | 1974 |
"In vitro" biosynthesis of androgens by rat submaxillary glands.
Topics: Androgens; Animals; Dehydroepiandrosterone; In Vitro Techniques; Pregnenolone; Progesterone; Rats; Submandibular Gland | 1965 |
Determination of oxo steroids as coloured salts of their Girard derivatives.
Topics: 17-Ketosteroids; Androgens; Androsterone; Chromatography, Paper; Colorimetry; Dehydroepiandrosterone; Estrone; Etiocholanolone; Hydrocortisone; Indicators and Reagents; Ketones; Pregnenolone; Progesterone; Quaternary Ammonium Compounds; Testosterone | 1964 |
Steroid metabolism in the syndrome of testicular feminization.
Topics: 17-Ketosteroids; Chemistry Techniques, Analytical; Chorionic Gonadotropin; Chromatography; Dehydroepiandrosterone; Dexamethasone; Disorders of Sex Development; Female; Follicle Stimulating Hormone; Humans; In Vitro Techniques; Male; Pregnenolone; Progesterone; Subcellular Fractions; Testis; Testosterone; Urine | 1965 |
Demonstration of 3-beta-hydroxysteroid dehydrogenase in the testis of Tilapia mossambica (Cichlidae, Teleostei).
Topics: Animals; Dehydroepiandrosterone; Fishes; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Pregnenolone; Testis; Tetrazolium Salts | 1966 |
In vitro testosterone synthesis by rat testicular tissue.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Rats; Subcellular Fractions; Testis; Testosterone | 1965 |
7-alpha-hydroxylation of delta-5-pregnenolone and of its conjugates by rat-liver microsomes.
Topics: Animals; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Glucuronates; In Vitro Techniques; Liver; Microsomes; Pregnenolone; Rats; Sulfates | 1966 |
[Biological half-life periods of C21-steroids in guinea pigs].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Blood; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1966 |
Gas chromatographic-mass spectrometric studies on solvolyzable steroids in human peripheral plasma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androsterone; Bile Acids and Salts; Blood Chemical Analysis; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Etiocholanolone; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Spectrum Analysis; Steroids; Testosterone | 1966 |
Formation of estrogens by hydatidiform moles in vitro.
Topics: Carbon Isotopes; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; Hydatidiform Mole; In Vitro Techniques; Mevalonic Acid; Pregnancy; Pregnenolone; Tritium | 1966 |
Adrenal secretion rates of C-19 and C-21 steroids before and after hypophysectomy in the pig and the dog.
Topics: Adrenal Glands; Androgens; Animals; Chromatography, Gas; Dehydroepiandrosterone; Dogs; Hydroxyprogesterones; Hypophysectomy; Pregnenolone; Progesterone; Secretory Rate; Swine; Testosterone | 1966 |
Neutral steroid sulphation and oestrogen biosynthesis in vitro by a feminizing Leydig cell tumour of the testis.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estriol; Humans; Hydroxyprogesterones; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Sulfates | 1966 |
Digitonin precipitable steroids in normal human urine.
Topics: 17-Ketosteroids; Adult; Androgens; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Humans; Male; Pregnenolone; Saponins; Steroids | 1966 |
Steroid hormone transformations by endocrine organs from pregnant mammals. I. Estrogen biosynthesis by mammalian placental preparations in vitro.
Topics: Alcohol Oxidoreductases; Androgens; Animals; Cattle; Dehydroepiandrosterone; Estradiol; Estrone; Guinea Pigs; Horses; In Vitro Techniques; Placenta; Pregnenolone; Progesterone; Rats; Sheep; Swine | 1966 |
Conversion of 20-alpha-hydroxycholesterol in vitro to pregnenolone sulfate by the human adrenal.
Topics: Adrenal Glands; Adult; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Pregnenolone | 1966 |
Column liquid-liquid partition chromatography of steroidal sulfates.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Cholesterol; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Pregnanediol; Pregnenolone; Steroids; Sterols; Sulfates | 1966 |
Steroid hormone formation by testes of a male pseudohermaphrodite.
Topics: Adult; Androgens; Androsterone; Carbon Isotopes; Chorionic Gonadotropin; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Estrogens; Humans; Hydroxyprogesterones; In Vitro Techniques; Leydig Cells; Male; Pregnenolone; Progesterone; Progestins; Radioisotope Dilution Technique; Testis; Testosterone | 1967 |
Steroid metabolism of a Sertoli cell tumour of the testis of a dog with feminization and alopecia and of the normal canine testis.
Topics: Alopecia; Animals; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Dog Diseases; Dogs; Male; Pregnenolone; Sertoli Cell Tumor; Testis; Tritium | 1967 |
Effect of steroids on germinal vesicle of oocytes of the frog (Rana pipiens) in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Aldosterone; Androgens; Animals; Anura; Cell Nucleus; Cholesterol; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Hydrocortisone; In Vitro Techniques; Ovum; Pregnanediol; Pregnenolone; Progesterone; Steroids; Testosterone | 1967 |
Purification and properties of 3-beta-hydroxysteroid dehydrogenase and delta-5-3-ketosteroid isomerase from bovine corpora lutea.
Topics: 17-Ketosteroids; Animals; Cattle; Corpus Luteum; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Kinetics; Pregnenolone; Spectrophotometry | 1966 |
Site specificity of bovine adrenal 3-beta-hydroxysteroid dehydrogenase and delta-5-3-ketosteroid isomerase.
Topics: Adrenal Glands; Animals; Cattle; Centrifugation; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Kinetics; Microsomes; Pregnenolone; Spectrophotometry; Steroids | 1967 |
Identification of steroid hormones from Lacerta sicula testes.
Topics: Androgens; Androsterone; Animals; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Male; Pregnenolone; Progesterone; Reptiles; Spectrophotometry; Testis; Testosterone | 1967 |
Incorporation of 7-alpha-3h-pregnenolone and 4-14C-progesterone into corticosteroids and some of their ester sulfates by human newborn adrenal slices.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Infant, Premature; Pregnenolone; Progesterone; Radiometry; Steroids; Sulfates; Tritium | 1967 |
Intracellular distribution and properties of steroid 16-alpha-hydroxylase in human testes.
Topics: Aged; Androgens; Carbon Isotopes; Castration; Chromatography, Thin Layer; Dehydroepiandrosterone; Hexestrol; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis | 1967 |
Enzymatic activities related to steroidogenesis in postmenopausal ovaries of patients with and without endometrial carcinoma.
Topics: Adenocarcinoma; Aged; Androgens; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Endometrium; Estrogens; Female; Humans; Menopause; Middle Aged; Pregnenolone; Progesterone; Uterine Neoplasms | 1967 |
In vivo steroidogenesis by the human adrenal gland.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Androsterone; Breast Neoplasms; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Pregnenolone; Steroids; Tritium | 1967 |
Testosterone biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Carbon Isotopes; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1967 |
Pathways for androgen biosynthesis in monkey testis.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Haplorhini; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1967 |
Metabolic clearance rates of pregnenolone, 17-acetoxypregnenolone and their sulphate esters in man and in rabbit.
Topics: Animals; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Glucocorticoids; Humans; Metabolic Clearance Rate; Pregnenolone; Rabbits; Sulfates; Testosterone; Tritium | 1967 |
Binding of the sulphate esters of dehydroepiandrosterone, testosterone, 17-acetoxypregnenolone and pregnenolone in the plasma of man, rabbit and rat.
Topics: Animals; Binding Sites; Cholesterol; Dehydroepiandrosterone; Glucocorticoids; Humans; Pregnenolone; Rabbits; Rats; Sulfates; Testosterone | 1967 |
The conversion of pregnenolone to progesterone and 16 alpha-hydroxydehydroepiandrosterone in vitro by adrenal tissue from a newborn anencephalic infant.
Topics: Adrenal Glands; Androgens; Androstanes; Anencephaly; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Estriol; Histocytochemistry; Humans; Hydrocortisone; Infant, Newborn; Infant, Newborn, Diseases; Lyases; Mixed Function Oxygenases; Pregnenolone; Progesterone | 1968 |
Further studies upon steroid transformations in the human corpus luteum.
Topics: 17-Ketosteroids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Corpus Luteum; Crystallization; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Radiochemistry; Testosterone | 1967 |
Conversion of pregnenolone-7-alpha-3H-sulfate to other delta-5-3-beta-hydroxysteroid sulfates by the human fetal adrenal in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; In Vitro Techniques; Perfusion; Pregnancy; Pregnanes; Pregnenolone; Sulfates; Tritium | 1968 |
Aalysis of solvolyzable steroids in human plasma by combined gas chromatography - mass spectrometry.
Topics: Acetates; Adult; Androsterone; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Etiocholanolone; Humans; Male; Pregnenolone; Solvents; Spectrum Analysis; Steroids; Sulfates | 1968 |
Distribution of hydroxysteroid dehydrogenases in the placenta of the pig.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Animals; Castration; Dehydroepiandrosterone; Epithelium; Estradiol; Estrogens; Etiocholanolone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Ovary; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Swine; Trophoblasts | 1968 |
Ribonucleic acid control of steroid synthesis in human adrenals and testes.
Topics: Adrenal Glands; Androgens; Animals; Corticosterone; Culture Techniques; Dehydroepiandrosterone; Fetus; Humans; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Mice; Pregnenolone; RNA; Steroids; Testis; Testosterone; Tritium | 1968 |
[Excretion of C-19 and C21 steroids in the urine under normal and pathological conditions of development and maturation].
Topics: 17-Ketosteroids; Adolescent; Adult; Age Factors; Androsterone; Carbon Isotopes; Child; Child, Preschool; Chromatography, Paper; Colorimetry; Cortisone; Dehydroepiandrosterone; Etiocholanolone; Female; Glucocorticoids; Growth; Humans; Hydrocortisone; Hypogonadism; Infant; Infant, Newborn; Male; Pregnenolone; Progesterone; Puberty, Precocious; Testosterone | 1967 |
[Effect of gonadotropins on the adrenal cortex. II. Incubation of adrenal homogenates from normal and castrated guinea pigs with 7alpha-3H-cholesterol under the influence of serum gonadotropin].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Animals; Cholesterol; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Glucuronates; Glycolipids; Gonadotropins; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Sulfates; Tritium | 1967 |
Adrenal delta 5-3 beta-hydroxysteroid dehydrogenase as related to vitamin A.
Topics: Adrenal Glands; Animals; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Kinetics; Male; Pregnenolone; Rats; Vitamin A; Vitamin A Deficiency | 1968 |
Biosynthesis of cortisol from 3 beta, 17 alpha,21-trihydroxypregn-5-en-20-one by the intact human foetus at midpregnancy.
Topics: Acetates; Adrenal Glands; Chromatography, Paper; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrocortisone; Perfusion; Pregnancy; Pregnenolone; Radioisotope Dilution Technique; Steroids; Tritium | 1968 |
The influence of thyroid function on adrenal 3-beta-hydroxy-steroid-dehydrogenase activity of the rat.
Topics: Adrenal Glands; Androgens; Animals; Chromatography, Paper; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Pregnenolone; Progesterone; Rats; Thyroid Gland; Thyroidectomy; Thyroxine | 1968 |
Sex hormones in the ovaries of the lizard Lacerta sicula.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Lizards; Male; Ovary; Physiology, Comparative; Pregnenolone; Progesterone; Snakes; Spectrophotometry; Testis; Tissue Extracts | 1968 |
The biosynthesis of some androst-16-enes from C21 and C19 steroids in boar testicular and adrenal tissue.
Topics: Adrenal Glands; Androstanes; Animals; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Kinetics; Male; Pregnenolone; Progesterone; Swine; Testis; Testosterone; Tritium | 1968 |
Comparisons of the dehydroisoandrosterone-delta-5-3-beta-hydroxysteroid dehydrogenase and the delta-5-pregnenolone-delta-5-3-beta-hydroxysteroid dehydrogenase activities of ovaries of control, hemiovariectomized, gonadotrophin-treated and "androgen-steril
Topics: Animals; Castration; Chemosterilants; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Gonadotropins, Equine; Hydroxysteroid Dehydrogenases; Infertility, Female; Luteinizing Hormone; Ovary; Ovulation; Pregnenolone; Prolactin; Rats; Testosterone | 1968 |
Steroid sulfates in human bile.
Topics: Androsterone; Bile; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Methods; Pregnenolone; Spectrum Analysis; Steroids; Sulfates | 1968 |
Assay of delta5-3beta-hydroxysteroid dehydrogenase in fish ovaries.
Topics: Animals; Biochemical Phenomena; Biochemistry; Dehydroepiandrosterone; Female; Fishes; Hydroxysteroid Dehydrogenases; Methods; Ovary; Pregnenolone; Spectrophotometry; Ultraviolet Rays | 1968 |
In vivo perfusion of the human adrenal gland and ovary in patients with mammary cancer.
Topics: Adrenal Glands; Androgens; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Female; Humans; Hydrocortisone; Ovary; Perfusion; Pregnenolone; Progesterone; Testosterone; Tritium | 1968 |
[Estrogen metabolism in normal human chorionic tissue, with special reference to the effect of chorionic gonadotropin].
Topics: Androgens; Androsterone; Chorionic Gonadotropin; Chromatography, Paper; Colorimetry; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Ethanol; Female; Gestational Age; Humans; Hydroquinones; Hydroxyprogesterones; In Vitro Techniques; Placenta; Pregnancy; Pregnenolone; Testosterone | 1968 |
Conjugation of steroid hormones by normal and neoplastic tissues.
Topics: Adult; Aged; Breast; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Female; Humans; Hydrogen-Ion Concentration; Liver; Liver Neoplasms; Middle Aged; Nandrolone; Neoplasm Metastasis; Pregnenolone; Steroids; Sulfates; Sulfur Isotopes; Transferases | 1968 |
[The steroid hormone formation in human ovaries in the course of the cycle].
Topics: Androgens; Dehydroepiandrosterone; Estrogens; Female; Gonadal Steroid Hormones; Humans; Kidney; Liver; Ovary; Ovulation; Pregnenolone; Progesterone; Testosterone | 1968 |
Enzymic synthesis of steroid sulphates. VII. Association-dissociation equilibria in the steroid alcohol sulphotransferase of human adrenal gland extracts.
Topics: Adenine Nucleotides; Adrenal Glands; Centrifugation, Density Gradient; Cholesterol; Chromatography, Gel; Chromatography, Paper; Cysteine; Dehydroepiandrosterone; Feedback; Female; Freezing; Humans; Hydrogen-Ion Concentration; Kinetics; Magnesium; Molecular Weight; Pregnenolone; Preservation, Biological; Stimulation, Chemical; Sulfates; Sulfhydryl Compounds; Sulfur Isotopes; Transferases | 1968 |
Steroid hormone formation in the human ovary. VI. Evidence for two pathways of synthesis of androgens in the stromal compartment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Biotransformation; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Ovary; Pregnancy; Pregnenolone; Progesterone; Spectrophotometry; Testosterone; Tritium | 1968 |
Biosynthesis of sterols and steroids from acetate-14-C by human fetal ovaries.
Topics: Acetates; Androstanes; Caproates; Carbon Isotopes; Cholestanes; Cholesterol; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; In Vitro Techniques; Ovary; Pregnancy; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Sterols; Testosterone; Tritium | 1968 |
De novo steriod sulfate biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Adrenal Glands; Androgen-Insensitivity Syndrome; Carbon Isotopes; Cholesterol; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Male; Pregnanes; Pregnenolone; Sulfates; Testis | 1968 |
Steroid metabolic pathways in feminizing testicular tissue.
Topics: 17-Ketosteroids; Acetone; Adolescent; Androgen-Insensitivity Syndrome; Androstanes; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Ethanol; Humans; In Vitro Techniques; Male; Methanol; Pregnenolone; Progesterone; Testis; Testosterone; Tritium; Water | 1968 |
Another pathway of oestriol biosynthesis in pregnancy.
Topics: 17-Ketosteroids; Adrenal Glands; Anencephaly; Carbon Isotopes; Dehydroepiandrosterone; Estriol; Female; Humans; In Vitro Techniques; Infant, Newborn; Pregnancy; Pregnenolone; Tritium | 1968 |
On the occurrence of phenol and steroid sulphokinases in the human gastrointestinal tract.
Topics: Adult; Androsterone; Biopsy; Colon; Colon, Sigmoid; Dehydroepiandrosterone; Desoxycorticosterone; Estrone; Etiocholanolone; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Ileum; Intestinal Mucosa; Jejunum; Phenols; Pregnenolone; Stomach; Sulfur Isotopes; Testosterone; Transferases | 1968 |
Secretion of neutral steroid sulfates by the human testis.
Topics: Adult; Aged; Androstanes; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Humans; Leydig Cells; Male; Pregnenolone; Spectrum Analysis; Sterols; Sulfates; Testis; Testosterone; Veins | 1969 |
[Esterification of sterols with fatty acids and with succinic acid in mycobacteria].
Topics: Bacteria; Carbon Isotopes; Cholestanes; Chromatography, Ion Exchange; Dehydroepiandrosterone; Esters; Fatty Acids; Fermentation; Mycobacterium; Pregnenolone; Sterols; Succinates; Tritium | 1969 |
Metabolism of (3H) pregnenolone by adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Infant, Newborn; Pregnenolone; Progesterone; Sulfates; Tritium | 1968 |
Steroid biosynthesis in vitro and in tissue culture by adrenal tumours of mice of the CE strain.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Culture Techniques; Dehydroepiandrosterone; Desoxycorticosterone; Female; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; Pregnenolone; Rodent Diseases; Steroids; Tritium | 1968 |
Binding of pregnenolone and progesterone by prostatic "receptor" proteins.
Topics: Androstanes; Animals; Binding Sites; Centrifugation, Density Gradient; Chromatography; Chromatography, Paper; Chromatography, Thin Layer; Cytoplasm; Dehydroepiandrosterone; In Vitro Techniques; Male; Pregnenolone; Progesterone; Prostate; Protein Binding; Proteins; Rats; Receptors, Drug; Testosterone; Tritium | 1969 |
Steroid hormone transformations by endocrine organs from pregnant mammals. IV. Biosynthesis and metabolism of estrogens and progesterone by primate placental preparations in vitro.
Topics: Androstanes; Animals; Biotransformation; Carbon Isotopes; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Dydrogesterone; Estradiol; Estrogens; Estrone; Female; Haplorhini; Humans; Hydroxyprogesterones; In Vitro Techniques; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediol; Pregnenolone; Progesterone; Species Specificity; Tritium | 1969 |
Virilizing male pseudohermaphroditism. Association with abnormal testicular function.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Chorionic Gonadotropin; Dehydroepiandrosterone; Disorders of Sex Development; Humans; Hydroxyprogesterones; Hyperplasia; Leydig Cells; Male; Pregnenolone; Progesterone; Testis; Testosterone; Virilism | 1969 |
[In vitro experiments on steroid hormone formation in the corpus luteum, stroma, hilum and follicles of the normal human ovary].
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstanes; Autoradiography; Carbon Isotopes; Chromatography, Thin Layer; Corpus Luteum; Corpus Luteum Hormones; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone | 1968 |
Partition column chromatography of steroid triethylammonium sulfates.
Topics: Androstanes; Androsterone; Cholesterol; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Pregnanediol; Pregnanes; Pregnenolone; Quaternary Ammonium Compounds; Steroids; Sulfates | 1969 |
De novo formation and metabolism of steroid hormones in feminizing testes: biochemical and ultrastructural studies.
Topics: 17-Ketosteroids; Acetates; Adult; Androgen-Insensitivity Syndrome; Androstanes; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Humans; Male; Microscopy, Electron; Pregnenolone; Sterols; Sulfatases; Sulfates; Testis; Testosterone | 1969 |
Conjugation of steroid hormones by breast cancer tissue and selection of patients for adrenalectomy.
Topics: Adrenalectomy; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Humans; Liver; Liver Neoplasms; Middle Aged; Neoplasm Metastasis; Pregnenolone; Sulfur Isotopes; Sulfuric Acids; Testosterone | 1969 |
Steroid inhibition of cholesteryl sulphate cleavage in vitro by rat testis tissue.
Topics: Animals; Cholesterol; Dehydroepiandrosterone; Depression, Chemical; Gonadal Steroid Hormones; In Vitro Techniques; Kinetics; Male; Pregnenolone; Rats; Sulfatases; Sulfates; Testis; Testosterone | 1969 |
[Meaning of the foeto-placental unit in the steroid metabolism].
Topics: Adrenal Insufficiency; Androgens; Anencephaly; Dehydroepiandrosterone; Disorders of Sex Development; Embryonic and Fetal Development; Enzyme Repression; Estradiol; Estriol; Estrogens; Female; Fetus; Humans; Lyases; Metabolism, Inborn Errors; Placenta; Pregnancy; Pregnanediol; Pregnenolone; Sex Determination Analysis; Steroids; Sulfatases | 1969 |
Biosynthesis of allo-3-beta-tetrahydrocortisol (Reichstein's substance V) by an adrenal adenoma.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Androstanes; Carbon Isotopes; Chemistry, Clinical; Corticosterone; Crystallization; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydrocortisone; Pregnenolone | 1969 |
Regulation of rat testis steroid sulfatase. A kinetic study.
Topics: Adrenal Cortex Hormones; Animals; Cholesterol; Dehydroepiandrosterone; Depression, Chemical; Esters; Estradiol; Feedback; Hydrocortisone; Kinetics; Male; Pregnenolone; Rats; Steroids; Sulfatases; Sulfates; Testis; Testosterone; Tritium | 1969 |
Determination of steroid mono- and disulfates in human plasma.
Topics: Adult; Androgens; Androstanes; Androsterone; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Electrophoresis; Female; Humans; Male; Methods; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Sulfates | 1969 |
1-14C-acetyl-coenzyme A as steroid precursor in the monkey adrenal in vitro.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Coenzyme A; Crystallization; Dehydroepiandrosterone; Haplorhini; In Vitro Techniques; Pregnenolone; Progesterone; Tritium | 1969 |
Effect of vitamin A on enzymic conversion of the delta-5-3-beta-hydroxy- into delta-4-3-oxosteroids by adrenals of the rat.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acids; Adrenal Glands; Age Factors; Androstanes; Animals; Body Weight; Castration; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Vitamin A; Vitamin A Deficiency; Weaning | 1969 |
Two cases of germinal aplasia: plasma concentration and in vitro biosynthesis of androgens.
Topics: 17-Ketosteroids; Adult; Androgens; Carbon Isotopes; Dehydroepiandrosterone; Eczema; Estradiol; Estrone; Humans; Hypogonadism; In Vitro Techniques; Infertility, Male; Libido; Male; Pregnenolone; Radiation Effects; Testicular Diseases; Testis; Testosterone | 1968 |
[Aspects of steroid biosynthesis in normal human testes].
Topics: 17-Ketosteroids; Adult; Aged; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Gonadotropins; Humans; Male; Middle Aged; Pregnenolone; Progesterone; Testis; Testosterone | 1968 |
Quantitation of C19O2 and C21O2 steroid mono- and disulfates in human bile.
Topics: 17-Hydroxycorticosteroids; Adult; Androstanes; Androsterone; Bile; Carbon; Chemical Phenomena; Chemistry; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Fistula; Gallbladder; Humans; Male; Middle Aged; Oxygen; Pregnanediol; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Sulfates; Tritium | 1969 |
Steroid metabolism by badger (Taxidea taxus) ovarian tissue homogenates.
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Carnivora; Chromatography, Paper; Chromatography, Thin Layer; Corpus Luteum; Crystallization; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Kinetics; Lyases; Mixed Function Oxygenases; Ovary; Pregnancy; Pregnenolone; Tritium | 1969 |
A comparative study of steroid biosyntheses in vitro. In clear cell adenoma and its adjacent tissue of human adrenal gland.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Carbon Isotopes; Chromatography, Thin Layer; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Steroids; Testosterone | 1969 |
Rat testis steroid sulfatase. 2. Kinetic study.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Estrone; Kinetics; Male; Pregnenolone; Rats; Steroids; Sulfatases; Sulfates; Testis; Testosterone; Tritium | 1969 |
Anti-androgens and their effect on androgen biosynthesis in the sebaceous gland.
Topics: Adult; Androgen Antagonists; Androgens; Dehydroepiandrosterone; Estradiol; Histocytochemistry; Histological Techniques; Humans; Hydroxysteroid Dehydrogenases; Pregnenolone; Sebaceous Glands; Testosterone | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium | 1969 |
Identification of C19O2 and C21O2 steroids in the glucuronide fraction of human bile.
Topics: 17-Hydroxycorticosteroids; Androstanes; Androsterone; Bile; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Dextrans; Etiocholanolone; Glucuronates; Glucuronidase; Humans; Methods; Pregnanediol; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Tritium | 1969 |
Androgen biosynthesis from C21 steroids by adrenal glands of newborn anencephalic infants.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Anencephaly; Dehydroepiandrosterone; Humans; In Vitro Techniques; Infant, Newborn; Pregnenolone; Progesterone; Testosterone | 1969 |
In vitro biosynthesis of sterols and steroids by rat submaxillary glands.
Topics: Acetates; Animals; Carbon Isotopes; Cholesterol; Chromatography, Paper; Crystallization; Dehydroepiandrosterone; Digitalis Glycosides; In Vitro Techniques; Indicators and Reagents; Male; Pregnenolone; Rats; Submandibular Gland | 1969 |
Steroidal and gonadotropin evaluation of a patient with a feminizing tumor of the adrenal gland. In vivo and in vitro studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenalectomy; Chromatography; Dehydroepiandrosterone; Desoxycorticosterone; Dexamethasone; Estradiol; Estriol; Estrogens; Feminization; Follicle Stimulating Hormone; Gonadotropins; Humans; Hydrocortisone; In Vitro Techniques; Luteinizing Hormone; Male; Metabolism, Inborn Errors; Middle Aged; Mixed Function Oxygenases; Nephrectomy; Prednisone; Pregnenolone; Radioimmunoassay; Sex Characteristics; Tritium | 1969 |
In vivo and in vitro studies of androgen metabolism in a patient with pure gonadal dysgenesis and Leydig cell hyperplasia.
Topics: 17-Hydroxycorticosteroids; Acetates; Adult; Androgens; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Hyperplasia; In Vitro Techniques; Leydig Cells; Luteinizing Hormone; Male; Metabolic Clearance Rate; Pregnenolone; Testicular Diseases; Testosterone; Turner Syndrome | 1969 |
Biosynthesis of 5-androstenediol by human testis in vitro.
Topics: Aged; Androstanes; Carbon Isotopes; Castration; Chromatography, Paper; Dehydroepiandrosterone; Humans; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Testis | 1970 |
Testicular feminizing syndrome and "pure" gonadal dysgenesis. Report of cases and in vitro studies with testes homogenate.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Androgen-Insensitivity Syndrome; Carbon Isotopes; Chromatography; Dehydroepiandrosterone; Estrogens; Female; Humans; In Vitro Techniques; Karyotyping; Male; Pregnenolone; Progesterone; Sex Chromosomes; Testis; Testosterone; Tissue Extracts; Tritium; Turner Syndrome | 1970 |
A novel steroidal aromatization reaction.
Topics: Chemical Phenomena; Chemistry; Cholesterol; Dehydroepiandrosterone; Hydantoins; Infrared Rays; Magnetic Resonance Spectroscopy; Pregnenolone; Spectrum Analysis; Steroids | 1970 |
A new pathway of oestriol biosynthesis in pregnancy?
Topics: Adrenal Cortex Hormones; Adrenal Glands; Androsterone; Anencephaly; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Estriol; Estrone; Female; Fetus; Humans; In Vitro Techniques; Infant, Newborn; Pregnancy; Pregnenolone; Tritium | 1969 |
Neutral steroid sulfates in human ovarlian vein blood.
Topics: Adult; Androstanes; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Female; Humans; Middle Aged; Ovary; Polycystic Ovary Syndrome; Pregnanes; Pregnenolone; Progesterone; Spectrophotometry; Sulfates; Veins | 1970 |
Metabolic pathways of steroid biosynthesis in ovarian tissue of a teleost, Tilapia aurea.
Topics: Animals; Carbon Isotopes; Dehydroepiandrosterone; Female; Fishes; Ovary; Pregnenolone; Progesterone; Testosterone; Tritium | 1970 |
Steroids in germfree and conventional rats. Sulpho- and glucuronohydrolase activities of caecal contents from conventional rats.
Topics: Adrenal Cortex Hormones; Animals; Bacteria; Carbon Isotopes; Cecum; Cholesterol; Chromatography, Gas; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Esters; Feces; Female; Germ-Free Life; Glucuronidase; Male; Pregnanes; Pregnenolone; Rats; Spectrum Analysis; Steroids; Sulfatases; Sulfuric Acids; Testosterone; Time Factors; Tritium | 1970 |
Mechanisms of action of clomiphene.
Topics: Animals; Clomiphene; Corpus Luteum; Dehydroepiandrosterone; Estrogens; Female; Gonadotropins; In Vitro Techniques; Isomerases; Ovulation; Oxidoreductases; Penicillium; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1969 |
Biosynthesis of estrogens in the human placenta.
Topics: 17-Ketosteroids; Acetates; Androstanes; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Humans; In Vitro Techniques; Perfusion; Placenta; Pregnenolone; Progesterone; Testosterone; Tritium | 1970 |
Presence of testosterone and other neutral steroids in human fetal testes.
Topics: 17-Ketosteroids; Androgens; Androstanes; Chromatography, Gas; Dehydroepiandrosterone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sulfuric Acids; Testis; Testosterone | 1970 |
Identification of C19O2 and C21O2 steroids in the mono- and disulphate fractions of human faeces.
Topics: 17-Hydroxycorticosteroids; Adult; Androstanes; Bile; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Dehydroepiandrosterone; Feces; Humans; Male; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Sulfates | 1970 |
Estrogen synthesis by adrenal-placental tissues of the sheep and the iris monkey in vitro.
Topics: Adrenal Glands; Androstanes; Animals; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Haplorhini; In Vitro Techniques; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Sheep; Testosterone | 1970 |
Histochemical demonstration of hydroxysteroid dehydrogenase activity in the mature canine ovary.
Topics: Androsterone; Animals; Corpus Luteum; Dehydroepiandrosterone; Dogs; Estradiol; Estrus; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Ovary; Pregnancy; Pregnenolone | 1970 |
In vitro steroidogenesis in the testicular tissue of the fresh water teleost Esox lucius.
Topics: 17-Ketosteroids; Androstanes; Animals; Chromatography, Gas; Dehydroepiandrosterone; Fishes; In Vitro Techniques; Male; Pregnenolone; Progesterone; Steroids; Sterols; Testis; Testosterone | 1970 |
Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.
Topics: Androstanes; Animals; Carbon Isotopes; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Leydig Cell Tumor; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pregnenolone; Progesterone; Testosterone; Tritium | 1970 |
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium | 1970 |
Steroid excretion and biosynthesis with special reference to C19-delta16-steroids in an infant with a virilizing adrenocortical carcinoma.
Topics: Adrenal Gland Neoplasms; Androstanes; Androsterone; Carbon Isotopes; Carcinoma; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Infant; Pregnenolone; Progesterone | 1970 |
Identification and determination of neutral steroid sulphates in human foetal adrenal and liver tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androstanes; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Liver; Pregnanes; Pregnenolone; Progesterone; Tissue Extracts | 1970 |
The metabolism of steroids in the rabbit epididymis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Acetates; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Crystallization; Dehydroepiandrosterone; Epididymis; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; Pregnanes; Pregnenolone; Progesterone; Rabbits; Sterols; Testosterone; Tritium | 1970 |
Formation and metabolism of testosterone in rat skin.
Topics: 17-Ketosteroids; Androstanes; Animals; Back; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnanes; Pregnenolone; Progesterone; Rats; Scrotum; Skin; Testosterone; Vulva | 1970 |
Pathways of dehydroepiandrosterone sulphate biosynthesis in the human foetal adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Gas; Dehydroepiandrosterone; Fetus; Humans; In Vitro Techniques; Kinetics; Pregnenolone; Radioisotope Dilution Technique; Spectrum Analysis; Sulfates; Tritium | 1970 |
Patterns of steroid biosynthesis by human adrenals incubated in vitro with [7alpha-3H) pregnenolone: changes with (a) gestational age, (b) incubation period and (c) weight of incubated tissue.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Aged; Androstanes; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Radioisotope Dilution Technique; Steroids; Sulfates; Time Factors; Tritium | 1970 |
Proceedings of the society for endocrinology.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Glands; Cholesterol; Dehydroepiandrosterone; Estriol; Female; Fetus; Humans; Placenta; Pregnancy; Pregnenolone; Progesterone; Steroids | 1970 |
Steroids of invertebrates. IV. On the optic tentacle-gonadal axis in the control of the male-phase ovotestis in the slug (Ariolimax californicus).
Topics: Androstanes; Animals; Chromatography, Gas; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonads; Ketones; Male; Metyrapone; Neurosecretory Systems; Pregnenolone; Snails; Testosterone | 1970 |
Steroids of invertebrates. V. The in vitro biosynthesis of steroids by the male-phase ovotestis of the slug (Ariolimax californicus).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Biotransformation; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Crustacea; Dehydroepiandrosterone; Female; Gonads; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Insecta; Male; Mollusca; Pregnenolone; Snails; Steroids; Tritium | 1970 |
Steroid synthesis in a human virilising adrenal carcinoma - some unusual features.
Topics: Adrenal Gland Neoplasms; Adult; Androstanes; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hirsutism; Humans; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium; Virilism | 1970 |
Pregnenolone and pregnenolone sulfate metabolism by human fetal testes in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sulfatases; Sulfates; Testis; Tritium | 1970 |
Determination of unconjugated and sulfated neutral steroids in human fetal blood of early and mid-pregnancy.
Topics: Androstanes; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Placenta; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Spectrum Analysis; Steroids; Umbilical Cord | 1970 |
Dehydroepiandrosterone sulfatase in the prostate and seminal vesicles of the rat.
Topics: Adipose Tissue; Adrenal Glands; Animals; Chromatography, Gas; Dehydroepiandrosterone; Epididymis; Estrone; Male; Muscles; Organ Specificity; Pregnenolone; Prostate; Rats; Seminal Vesicles; Sulfatases; Time Factors | 1970 |
Labelling of steroids in axillary sweat after administration of 3H-delta-5-pregnenolone and 14C-progesterone to a healthy man.
Topics: 17-Hydroxycorticosteroids; Adult; Androstanes; Axilla; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Male; Pregnanediol; Pregnanes; Pregnenolone; Progesterone; Sterols; Sweat; Tritium | 1970 |
Sexual differences in the biogenesis of the androgens by the adrenal cortex in rat.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Androstanes; Animals; Chromatography, Paper; Chromatography, Thin Layer; Corticosterone; Crystallization; Dehydroepiandrosterone; Female; In Vitro Techniques; Male; Pregnenolone; Rats; Sex Factors; Testosterone; Tritium | 1970 |
Metabolism of ovarian steroids in a patient with chronic familial anovulation.
Topics: Adult; Androstanes; Androsterone; Chronic Disease; Dehydroepiandrosterone; Estranes; Estriol; Estrone; Female; Humans; Ovarian Diseases; Ovary; Ovulation; Pregnenolone; Radioisotope Dilution Technique | 1970 |
Steroids of a chondrostean: identification of interrenal tissue in the American Atlantic sturgeon, Acipenser oxyrhynchus Mitchill, by histological and histochemical methods.
Topics: Adrenal Glands; Androsterone; Animals; Corticosterone; Dehydroepiandrosterone; Female; Fishes; Histocytochemistry; Hydrocortisone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kidney; Male; Pregnenolone; Veins | 1970 |
Concentration of unconjugated estrogens, androgens and gestagens in ovarian and peripheral venous plasma of women: the normal menstrual cycle.
Topics: 17-Ketosteroids; Adult; Androstanes; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Dydrogesterone; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Menstruation; Ovary; Pregnenolone; Testosterone; Tritium; Veins | 1971 |
The fetoplacental unit.
Topics: Amniotic Fluid; Animals; Carbon Isotopes; Dehydroepiandrosterone; Embryonic and Fetal Development; Estriol; Estrogens; Female; Fetal Diseases; Fetus; Haplorhini; Humans; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Pregnenolone; Progesterone; Steroids | 1970 |
[Demonstration of the action of vitamin A on the conversion of delta 5-3 beta hydroxy into delta 4-3 oxo steroids by the adrenal cortex of white adult normal rats].
Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Animals; Chromatography; Dehydroepiandrosterone; Pregnenolone; Progesterone; Rats; Vitamin A | 1970 |
Studies on mammalian and molluscan steroid sulfatase. Solubilization and properties.
Topics: Animals; Cholesterol; Dehydroepiandrosterone; Detergents; Electrophoresis; Kinetics; Male; Microsomes, Liver; Molecular Weight; Pregnenolone; Rats; Snails; Solubility; Steroids; Sulfatases; Sulfuric Acids | 1971 |
A comparative histochemical study of delta 5-3 beta-hydroxysteroid dehydrogenase and lipid content in the rat ovary with special reference to the interstitial cells.
Topics: Animals; Dehydroepiandrosterone; Estrus; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Lipids; Ovary; Phospholipids; Pregnancy; Pregnenolone; Rats | 1970 |
[Experiments on the determination of estrogenic hormones in peripheral cattle blood by means of a radioimmunological assay].
Topics: Animals; Cattle; Corticosterone; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Hydrocortisone; Pregnenolone; Progesterone; Rabbits; Radioimmunoassay; Testosterone | 1971 |
[Metabolism of steroids in normal and pathological human adrenal glands].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adult; Androgens; Carbon Isotopes; Child, Preschool; Chromatography, Thin Layer; Cushing Syndrome; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Prostatic Neoplasms | 1971 |
Quantitative assessment of the de novo sterol and steroid synthesis in the human foeto-placental unit. 2. Synthesis and secretion of steroids and steroid sulphates by the midgestation foetus.
Topics: Abortion, Legal; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Humans; Perfusion; Placenta; Pregnancy; Pregnenolone; Sulfates | 1971 |
Excretion of neutral steroid hormones in human bile.
Topics: 17-Ketosteroids; Androsterone; Bile; Biliary Fistula; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Digestive System; Electrophoresis; Estrogens; Etiocholanolone; Female; Gallbladder; Glucuronates; Humans; Male; Pregnanediol; Pregnanetriol; Pregnenolone; Steroids; Sulfates | 1970 |
[Metabolism of pregnenolone and progesterone in the adrenal gland of the previable human fetus and the anencephalic infant].
Topics: Adrenal Glands; Anencephaly; Carbon Isotopes; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrocortisone; In Vitro Techniques; Intestinal Mucosa; Kidney; Liver; Lung; Pregnancy; Pregnenolone; Progesterone; Progestins; Tritium | 1971 |
[Separation of steroids and color indicators on ion exchange resin].
Topics: Androstanes; Anthraquinones; Azo Compounds; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Coloring Agents; Dehydroepiandrosterone; Indicators and Reagents; Pregnenolone; Progesterone; Steroids; Testosterone; Tritium | 1971 |
Studies on the inhibition of fetal androgen formation. Inhibition of testosterone synthesis in rat and rabbit fetal testes with observations on reproductive tract development.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Abnormalities, Drug-Induced; Androstanes; Animals; Carbon Isotopes; Cholestanes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Depression, Chemical; Female; Fetus; Genitalia, Male; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hypospadias; In Vitro Techniques; Indenes; Male; Perineum; Pregnancy; Pregnenolone; Pyridines; Rabbits; Rats; Testis; Testosterone; Wolffian Ducts | 1971 |
Steroids and sterols in meconium.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androsterone; Bile; Chromatography; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Glucuronates; Humans; Infant, Newborn; Intestine, Small; Maternal-Fetal Exchange; Meconium; Placenta; Pregnancy; Pregnanes; Pregnenolone; Spectrum Analysis; Steroids; Sterols; Testosterone | 1971 |
Histochemical demonstration of delta 5-3 beta-hyroxysteroid dehydrogenase activity in the interstitial tissue of the guinea pig ovary during the estrous cycle and pregnancy.
Topics: Animals; Connective Tissue; Corpus Luteum; Dehydroepiandrosterone; Estrus; Female; Guinea Pigs; Histocytochemistry; Hydroxysteroid Dehydrogenases; Ovary; Pregnancy; Pregnancy, Animal; Pregnenolone; Steroids | 1971 |
The production of hormonal steroids by ovarian tissues of the chinchilla (Chinchilla laniger).
Topics: Androstanes; Animals; Carbon Isotopes; Chinchilla; Chromatography, Gas; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Female; In Vitro Techniques; Ovarian Follicle; Ovary; Pregnanes; Pregnenolone; Progesterone; Testosterone; Tritium | 1971 |
Levels of 16-alpha-hydroxydehydroepiandrosterone, dehydroepiandrosterone and pregnenolone in cord plasma of human normal and anencephalic fetuses.
Topics: Adolescent; Adult; Aluminum; Androstanes; Anencephaly; Blood; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Estrogens; Female; Fetus; Humans; Infant, Newborn; Male; Oxides; Pregnancy; Pregnanediol; Pregnenolone; Statistics as Topic; Tritium; Umbilical Cord | 1971 |
[Hard-to-classify forms of intersexuality. 3. Biosynthesis of steroids in testis of a case of male pseudohermaphroditism].
Topics: Androgen-Insensitivity Syndrome; Cholesterol; Dehydroepiandrosterone; Disorders of Sex Development; Estrogens; Humans; Male; Mixed Function Oxygenases; Pregnenolone; Progesterone; Sulfur Isotopes; Testis; Testosterone; Tritium | 1970 |
1-Dimethylaminonaphthalene-5-sulfonyl hydrazine (dansyl hydrazine): a fluorometric reagent for carbonyl compounds.
Topics: Aldehydes; Androsterone; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Female; Fluorometry; Hydrazines; Indicators and Reagents; Ketones; Ketosteroids; Methods; Naphthalenes; Pregnancy; Pregnanes; Pregnenolone; Sulfonic Acids | 1971 |
Adrenal biogenesis in vivo of androgens and cortisol in the guinea-pig using a continuous infusion technique.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Androgens; Androstanes; Animals; Carbon Isotopes; Dehydroepiandrosterone; Female; Guinea Pigs; Hydrocortisone; Hydroxyprogesterones; Methods; Pregnenolone; Progesterone; Tritium | 1971 |
The in vitro formation of androstenedione from C 21 steroids by follicles isolated from human ovaries. A time study.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adult; Androstanes; Carbon Isotopes; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Time Factors; Tritium | 1971 |
The effect of dexamethasone on the urinary excretion of steroids during pregnancy.
Topics: 17-Ketosteroids; Adolescent; Adult; Dehydroepiandrosterone; Dexamethasone; Estriol; Estrogens; Female; Fetus; Humans; Placenta; Pregnancy; Pregnanediol; Pregnenolone; Progesterone; Terpenes; Tritium | 1971 |
Testicular tumors in the androgen insensitive pseudohermaphrodite rat: histochemistry and steroid metabolism.
Topics: Animals; Carbon Isotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Disease Models, Animal; Disorders of Sex Development; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cell Tumor; Leydig Cells; Male; Oxidoreductases; Pregnenolone; Rats; Sertoli Cell Tumor; Testicular Neoplasms; Testis; Tritium | 1970 |
Column chromatography of steroids on Sephadex LH-20.
Topics: 17-Ketosteroids; Androstanes; Benzene; Chloroform; Cholesterol; Chromatography, Gel; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estriol; Estrone; Hydroxyprogesterones; Methanol; Methods; Pregnanes; Pregnenolone; Progesterone; Solvents; Steroids; Sterols; Testosterone | 1971 |
Case of feminizing interstitial cell tumor of the testicle. Clinical and biochemical evaluation.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androgen-Insensitivity Syndrome; Androstanes; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estriol; Humans; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnanediol; Pregnanetriol; Pregnenolone; Testosterone; Tritium | 1971 |
Gonadal steroid sulfates and sulfatase. IV. Comparative studies on steroid sulfokinase in the human fetal testis and adrenal.
Topics: Adrenal Glands; Chromatography, Paper; Dehydroepiandrosterone; Female; Fetus; Humans; In Vitro Techniques; Male; Pregnancy; Pregnenolone; Sulfates; Testis; Testosterone; Transferases; Tritium | 1971 |
The separation of C19-16-unsaturated steroids from C21 and other C19-steroids by two-dimensional thin-layer chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstanes; Androsterone; Autoradiography; Chromatography, Thin Layer; Dehydroepiandrosterone; Estrogens; Etiocholanolone; Hydroxyprogesterones; Methods; Pregnenolone; Progestins; Testosterone | 1971 |
Enhancement of 3 -hydroxysteroid dehydrogenase-isomerase in the human fetal adrenal by removal of the soluble cell fraction.
Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Carbon Isotopes; Chromatography; Chromatography, Paper; Dehydroepiandrosterone; Enzyme Activation; Fetus; Humans; Hydroxysteroid Dehydrogenases; Microsomes; Pregnenolone; Subcellular Fractions; Tritium | 1971 |
Partial 3 -hydroxysteroid dehydrogenase (3 -HSD) deficiency in a family with congenital adrenal hyperplasia: evidence for increasing 3 -HSD activity with age.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Aging; Aldosterone; Androstanes; Androsterone; Child; Child, Preschool; Chlorides; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Etiocholanolone; Female; Glucuronates; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hyperkalemia; Hyperplasia; Hyponatremia; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Potassium; Pregnanetriol; Pregnenolone; Sodium; Sulfates; Testosterone | 1971 |
Metabolism of pregnenolone and dehydroepiandrosterone by homogenized tissue from the separated zones and whole adrenal glands from newborn anencephalic infants.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenosine Triphosphate; Adrenal Glands; Androstanes; Anencephaly; Dehydroepiandrosterone; Estrogens; Female; Fetus; Humans; Hydroxysteroid Dehydrogenases; Infant, Newborn; Isomerases; Lyases; Male; Mixed Function Oxygenases; Pregnenolone; Sulfates; Sulfurtransferases; Tritium | 1971 |
Site of dehydroepiandrosterone sulphate biosynthesis in the adrenal gland of the previable foetus.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Freezing; Humans; In Vitro Techniques; Male; Pregnenolone; Sulfates; Tritium | 1971 |
Interruption of pregnancy by various steroids.
Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Digitoxin; Estradiol; Ethylestrenol; Female; Indomethacin; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnenolone; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone | 1971 |
[Biosynthesis of steroids in a case of testicular feminization].
Topics: Adolescent; Androgen-Insensitivity Syndrome; Cholesterol; Dehydroepiandrosterone; Estrogens; Gonadotropins, Pituitary; Humans; Male; Pregnenolone; Sulfatases; Sulfates; Sulfur Isotopes; Sulfurtransferases; Testis; Testosterone; Tritium | 1971 |
[Steroid-hormones in the guinea pig].
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Animals; Body Weight; Chemotherapy, Cancer, Regional Perfusion; Dehydroepiandrosterone; Glucuronates; Guinea Pigs; Half-Life; Hydrocortisone; Kidney; Liver; Liver Circulation; Mononuclear Phagocyte System; Pregnenolone; Progesterone; Sulfates; Sulfoglycosphingolipids; Tritium | 1971 |
[Effects of steroid hormones on the proliferation of HeLa cells].
Topics: Androgens; Androsterone; Autoradiography; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estriol; Estrogens; Estrone; Etiocholanolone; Female; HeLa Cells; Humans; Hydrocortisone; Pregnanetriol; Pregnenolone; Progesterone; Progestins; Propylene Glycols; Testosterone; Tritium | 1971 |
Effect of substrate on histochemistry of 3-beta-hydroxysteroid dehydrogenase in lizard tests.
Topics: Animals; Dehydroepiandrosterone; Etiocholanolone; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Lizards; Male; Pregnenolone; Tetrazolium Salts | 1971 |
Steroid synthesis by the seminiferous tubules of the snake Naja naja.
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Histocytochemistry; In Vitro Techniques; Male; Pregnenolone; Progesterone; Sertoli Cells; Snakes; Steroids; Testis; Testosterone; Tritium | 1971 |
Impotence and diabetes. Studies of androgenic function in diabetic impotent males.
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Chorionic Gonadotropin; Dehydroepiandrosterone; Diabetes Complications; Diabetes Mellitus; Electromyography; Erectile Dysfunction; Humans; Kidney Function Tests; Leydig Cells; Male; Neural Conduction; Neurologic Examination; Paraplegia; Pregnenolone; Progesterone; Testis; Testosterone; Urinary Bladder | 1972 |
[Patterns of steroid biosynthesis in feminizing and normal testicles].
Topics: Androgen-Insensitivity Syndrome; Androgens; Androsterone; Animals; Dehydroepiandrosterone; Humans; Male; Mice; Pregnenolone; Testis | 1970 |
Activity of sterol-sulphate sulphohydrolase in rat brain: characterization, localization and change with age.
Topics: Acid Phosphatase; Age Factors; Animals; Brain; Brain Chemistry; Brain Stem; Carbon Isotopes; Cerebellum; Cerebral Cortex; Dehydroepiandrosterone; Diencephalon; Estrone; Galactosidases; Pregnenolone; Rats; Steroids; Subcellular Fractions; Sulfatases; Sulfates; Surface-Active Agents; Tritium | 1972 |
[Periodic changes of hydroxysteroid-dehydrogenase activity in the corpus luteum of cattle].
Topics: Animals; Cattle; Corpus Luteum; Cytoplasm; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydroxysteroid Dehydrogenases; Microsomes; Ovulation; Periodicity; Pregnanediol; Pregnenolone; Progesterone | 1972 |
Metabolism of C 19 steroids by homogenates of normal rat and mouse adrenal tissue, and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; In Vitro Techniques; Neoplasms, Experimental; Pregnenolone; Rats; Tritium | 1972 |
Gonadal steroid sulfates and sulfatase. V. Human testicular steroid sulfatase: partial characterization and possible regulation by free steroids.
Topics: Androstanes; Dehydroepiandrosterone; Drug Synergism; Humans; Hydrogen-Ion Concentration; Ketosteroids; Kinetics; Male; Microsomes; Oxidation-Reduction; Pregnanes; Pregnenolone; Steroids; Structure-Activity Relationship; Sulfatases; Sulfuric Acids; Testis; Testosterone; Tritium | 1972 |
Studies of the human testis. I. Biosynthetic pathways for androgen formation in human testicular tissue in vitro.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Aged; Androstanes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Progesterone; Prostatic Neoplasms; Testis; Testosterone; Time Factors; Tritium | 1972 |
Steroid biosynthesis in vitro by gonadal tissues in true hermaphroditism.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Dehydroepiandrosterone; Disorders of Sex Development; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Male; Ovary; Pregnanes; Pregnenolone; Progesterone; Sterols; Testis; Testosterone; Tritium | 1972 |
[Studies on steroid biosynthesis of in-vitro perfused bovine ovaries in various functional phases].
Topics: Androgens; Androsterone; Animals; Cattle; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrus; Female; Glucocorticoids; Hydroxyprogesterones; Mass Spectrometry; Ovary; Perfusion; Pregnancy; Pregnenolone; Testosterone | 1971 |
[Urinary 16- -hydroxylated- 5 -steroid of the newborn].
Topics: 17-Ketosteroids; Chromatography, Gas; Dehydroepiandrosterone; Humans; Infant, Newborn; Infant, Premature; Ketosteroids; Pregnenolone | 1971 |
Excretion of conjugates of neutral steroids in human bile during late pregnancy.
Topics: 17-Hydroxycorticosteroids; Adult; Androstanes; Androsterone; Bile; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Glucuronates; Humans; Mass Spectrometry; Pregnancy; Pregnanediol; Pregnenolone; Sterols; Time Factors | 1972 |
Testis steroid sulfatase activity in rats treated with chorionic gonadotrophin.
Topics: Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Hypophysectomy; Male; Pituitary Gland; Pregnenolone; Rats; Sulfatases; Sulfates; Testis; Testosterone; Time Factors; Tritium | 1972 |
Free and sulfate-conjugated neutral steroids in human testis tissue.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aged; Androstanes; Androsterone; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Humans; Hydroxysteroids; Ketosteroids; Male; Mass Spectrometry; Middle Aged; Pregnanediol; Pregnanes; Pregnenolone; Steroids; Sulfuric Acids; Testis; Testosterone | 1972 |
Comparative ultrastructural and histochemical studies of the interstitial cells of the rat testis during fetal and postnatal development.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cell Nucleolus; Dehydroepiandrosterone; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Hydroxysteroid Dehydrogenases; Lipids; Male; Microscopy, Electron; Mitochondria; Pregnenolone; Rats; Testis | 1972 |
17 -hydroperoxypregnenes. 3. Studies on their role as possible precursors in the biosynthesis of adrenosteroid hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aerobiosis; Anaerobiosis; Androstanes; Animals; Cattle; Chloromercuribenzoates; Chromatography, Gas; Dehydroepiandrosterone; Drug Stability; Glucocorticoids; Hot Temperature; Hydroxyprogesterones; Kinetics; Mass Spectrometry; Peroxides; Pregnenolone; Progesterone | 1972 |
Artifact formation during incubation of neutral steroids with commercial -glucuronidase preparations.
Topics: Androsterone; Animals; Anti-Bacterial Agents; Bacteria; Cattle; Chloroform; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Glucuronidase; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Liver; Mass Spectrometry; Methods; Mollusca; Pregnenolone; Progesterone; Snails; Steroids | 1972 |
Substrate-dependent beta-hydroxy steroid dehydrogenase activity in the gonads of the clawed toad (Xenopus laevis Daud.).
Topics: Animals; Dehydroepiandrosterone; Estradiol; Female; Hydroxysteroid Dehydrogenases; Male; Methods; Ovary; Pregnenolone; Testis; Xenopus | 1972 |
Radioligand assay for 5 -3 -hydroxysteroids. II. 5-Androstene-3 ,17 -diol and 3 ,17 -dihydroxy-5-pregnen-20-one.
Topics: Androstanes; Animals; Antibody Specificity; Cattle; Chromatography, Paper; Cross Reactions; Dehydroepiandrosterone; Female; Humans; Hydroxysteroids; Immune Sera; Ketosteroids; Male; Methods; Pregnenolone; Protein Binding; Rabbits; Radioimmunoassay; Serum Albumin, Bovine; Tritium | 1972 |
[Effects of steroids on glucose-6-phosphate dehydrogenase and lipid metabolism].
Topics: Adult; Androstanes; Androsterone; Blood Protein Disorders; Dehydroepiandrosterone; Female; Glucosephosphate Dehydrogenase; Humans; Lipid Metabolism; Lipoproteins; Male; Obesity; Pregnenolone; Protein Binding; Psoriasis | 1972 |
Biosynthesis of steroid hormones by testes and ovaries of the peludo, Chaetophractus villosus (Edentata, mammalia).
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Dehydroepiandrosterone; Female; Male; Ovary; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Testis; Xenarthra | 1972 |
Conversion of pregnenolone and pregnenolone sulfate to other steroid sulfates by the human fetus perfused at midgestation.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Carbon Isotopes; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Liver; Perfusion; Pregnancy; Pregnenolone; Sulfates; Tritium | 1972 |
In vitro steroid synthesis by follicles isolated from the rabbit ovary.
Topics: Acetates; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Countercurrent Distribution; Dehydroepiandrosterone; Estradiol; Estrone; Female; Glucocorticoids; Hydroxyprogesterones; In Vitro Techniques; Luteinizing Hormone; Ovary; Pregnenolone; Progesterone; Rabbits; Radioisotope Dilution Technique; Testosterone; Tritium | 1972 |
Metabolism of C 19 -steroids by homogenates of normal rat and mouse adrenal tissue and of the Snell transplantable rat adrenocortical tumour 494.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstanes; Androsterone; Animals; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Ketones; Mice; Neoplasms, Experimental; Pregnenolone; Rats; Steroids; Tritium | 1972 |
The development of steroidogenesis.
Topics: Adrenal Glands; Adult; Age Factors; Cholesterol; Dehydroepiandrosterone; Fetus; Humans; Infant, Newborn; Placenta; Pregnenolone; Progesterone; Steroids | 1972 |
Steroid biosynthesis in gonadal tissue from patients with testicular feminization.
Topics: Adult; Aging; Androgen-Insensitivity Syndrome; Carbon Isotopes; Chromatography; Dehydroepiandrosterone; Estradiol; Humans; In Vitro Techniques; Male; Middle Aged; Pregnenolone; Sulfates; Testis; Testosterone; Tritium | 1972 |
A study of sterol and steroid synthesis from sodium acetate by human foetal liver preparations.
Topics: Acetates; Carbon Isotopes; Cholesterol; Chromatography, Paper; Countercurrent Distribution; Dehydroepiandrosterone; Female; Fetus; Humans; Liver; Pregnancy; Pregnenolone; Tritium | 1972 |
Bile acids and hormonal steroids in bile of a boy with 3 -hyseoxysteroid dehydrogenase deficiency.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androstenes; Androsterone; Animals; Bile; Bile Acids and Salts; Child; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Glucuronates; Humans; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Ketosteroids; Liver; Male; Mass Spectrometry; Metabolism, Inborn Errors; Pregnanes; Pregnenes; Pregnenolone; Sulfuric Acids | 1972 |
Steroid metabolism in kidney tissue. I. Endogenous neutral steroids in foetal kidneys and studies on their formation.
Topics: 17-alpha-Hydroxypregnenolone; Androsterone; Buffers; Chromatography; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; In Vitro Techniques; Kidney; Mass Spectrometry; Methods; Mixed Function Oxygenases; Oxidoreductases; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfates; Sulfurtransferases; Time Factors | 1972 |
De novo synthesis of steroids and steroid sulphates by the testicles of the human foetus at midgestation.
Topics: Androstenes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxyprogesterones; Male; Methods; Perfusion; Pregnancy; Pregnenolone; Progesterone; Scintillation Counting; Steroids; Temperature; Testis; Time Factors; Tritium | 1972 |
A study of pregnancy with low estrogen production due to placental sulfatase deficiency.
Topics: Adult; Blood; Carbon Isotopes; Catechols; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Male; Placenta; Pregnancy; Pregnanediol; Pregnanes; Pregnenolone; Sulfatases; Sulfates; Tritium; Umbilical Cord | 1973 |
[Function of the fetal adrenal cortex].
Topics: Adrenal Cortex Hormones; Adrenal Glands; Dehydroepiandrosterone; Female; Fetus; Gestational Age; Humans; Hydroxysteroid Dehydrogenases; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfurtransferases | 1972 |
Quantitative assessment of the principal steroids formed by human placentas perfused with labelled cholesterol in vitro.
Topics: Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Female; Humans; Oxygen; Perfusion; Placenta; Pregnancy; Pregnenolone; Progesterone; Tritium | 1973 |
In vitro steroidogenesis by testes of the chicken (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenes; Animals; Cell Fractionation; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Isomerases; Male; Microsomes; Oxidoreductases; Pregnenolone; Steroid Hydroxylases; Testis; Testosterone | 1972 |
Urinary steroid levels in newborn infants with intrauterine growth retardation.
Topics: Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Glucuronates; Growth Disorders; Humans; Hydrocortisone; Infant, Newborn; Infant, Newborn, Diseases; Methods; Pregnenolone; Sulfates; Tritium | 1973 |
In vitro metabolism of a mixture of (4- 14 C)pregnenolone and (17 - 3 H)pregnenolone by polycystic ovary: pathways of testosterone biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstenes; Carbon Isotopes; Chromatography, Paper; Crystallization; Cysts; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Ovarian Diseases; Ovary; Pregnenolone; Progesterone; Testosterone; Tritium | 1972 |
Histochemical studies on hydroxysteroid dehydrogenase activity of fetal pig testes.
Topics: Androsterone; Animals; Cell Differentiation; Dehydroepiandrosterone; Estradiol; Fetus; Gestational Age; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Pregnenolone; Swine; Testis; Testosterone | 1972 |
Developmental pattern of testosterone synthesis in the fetal gonad of the rabbit.
Topics: Androstenes; Animals; Carbon Isotopes; Chromatography; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Fetus; Male; Ovary; Placenta; Pregnancy; Pregnenolone; Progesterone; Rabbits; Testis; Testosterone; Tritium | 1973 |
Adrenal steroid biosynthesis from 4-14C-cholesterol (in vitro) during phenobarbital block of PMS-induced ovulation in immature rats.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Female; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Ovulation; Phenobarbital; Pregnenolone; Progesterone; Rats | 1973 |
[Comparative aspect of the synthesis of sex steroids by chick embryonal gonads at different stages of development (study in organ culture in the presence of radioactive precursors)].
Topics: Animals; Carbon Isotopes; Chick Embryo; Cholesterol; Dehydroepiandrosterone; Estrogens; Female; Gonads; Hydroxysteroid Dehydrogenases; Isoenzymes; Male; Ovary; Pregnenolone; Progesterone; Sodium; Testis; Testosterone; Time Factors; Tritium | 1973 |
Inhibition of steroidogenesis by cyanoketone.
Topics: Adrenal Glands; Androstenes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Crystallization; Culture Techniques; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Ketosteroids; Male; Nitriles; Pregnenolone; Progesterone; Rats; Testis; Testosterone | 1971 |
Human foetal adrenal 4-ene-3-oxosteroid synthesis: an investigation of (4- 14 C) pregnenolone and (4- 14 C)-dehydroepiandrosterone metabolism using new techniques.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Androstenes; Carbon Isotopes; Chromatography, Thin Layer; Cortisone; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Hydrocortisone; In Vitro Techniques; Methods; Pregnenolone; Progesterone; Testosterone; Tritium | 1973 |
Identification and measurement of sulphate-conjugated neutral steroids in the intestinal contents of early and mid-term foetuses.
Topics: 17-Hydroxycorticosteroids; Androstanes; Androstenes; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Fetus; Gestational Age; Humans; Intestines; Mass Spectrometry; Meconium; Pregnadienes; Pregnanes; Pregnanetriol; Pregnenolone; Steroids; Sterols; Sulfates | 1973 |
Elimination of tritium from metabolites of (16- 3 H)-pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androstenedione; Animals; Carbon Isotopes; Dehydroepiandrosterone; Hydrolysis; In Vitro Techniques; Male; Pregnenolone; Rabbits; Testis; Testosterone; Tritium | 1973 |
New synthetic steroids which inhibit rat gonadal steroidogenic enzymes both in vitro and in vivo.
Topics: Adrenalectomy; Androstanes; Animals; Carbon Isotopes; Castration; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Lyases; Male; Mass Spectrometry; Microsomes; Mixed Function Oxygenases; Ovary; Pregnanes; Pregnenolone; Progesterone; Rats; Testis; Tritium | 1973 |
Histochemical localization of 3 - and 17 -hydroxysteroid dehydrogenases in the male reprodutive tract of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Animals; Chickens; Dehydroepiandrosterone; Epididymis; Genitalia, Male; Histocytochemistry; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; Microscopy; Pregnenolone; Seminal Vesicles; Testis; Vas Deferens | 1973 |
The metabolic fate of pregnenolone-7 - 3 H and pregesterone-4- 14 C in the ovaries and fat bodies of female Triturus cristatus carnifex.
Topics: 17-alpha-Hydroxypregnenolone; Adipose Tissue; Animals; Carbon Isotopes; Castration; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Ovary; Pregnenolone; Progesterone; Seasons; Time Factors; Tritium; Triturus | 1973 |
[Several steroid derivatives in breast tumors. Histo-enzymological study].
Topics: Biopsy; Breast; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Female; Histocytochemistry; Humans; Oxidoreductases; Pregnenolone | 1973 |
Radioimmunoassay of plasma pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone under various physiological conditions.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Child; Chromatography; Climacteric; Dehydroepiandrosterone; Female; Humans; Immune Sera; Infant, Newborn; Male; Menstruation; Methods; Pregnancy; Pregnenolone; Puberty; Radioimmunoassay | 1973 |
[In vitro studies on the steroid metabolism in human spermatozoa].
Topics: Androstenedione; Autoradiography; Cell Movement; Dehydroepiandrosterone; Humans; Male; Pregnenolone; Progesterone; Spermatozoa; Testosterone | 1970 |
Some effects of steroids on the immature mouse ovary in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; Mice; Mitosis; Ovarian Follicle; Ovary; Pregnenolone; Progesterone; Steroids; Stimulation, Chemical; Testosterone; Thymidine; Tritium | 1973 |
Serum steroid levels during the menstrual cycle in a bilaterally adrenalectomized woman.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Gland Diseases; Adrenalectomy; Adult; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Menstruation; Ovary; Pregnenolone; Progesterone; Testosterone | 1973 |
Glucocorticoid synthesis from pregnenolone by sheep foetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Animals; Chromatography; Corticosterone; Dehydroepiandrosterone; Fetus; Gestational Age; Glucocorticoids; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Sheep | 1973 |
Steroid hormone production by pig blastocysts.
Topics: Androstenedione; Animals; Blastocyst; Carbon Radioisotopes; Dehydroepiandrosterone; Estradiol; Estrone; Hydrocortisone; In Vitro Techniques; Pregnenolone; Progesterone; Swine; Tritium | 1973 |
Ionic transport through model membranes. II. Function of cholesterol and steroid hormones.
Topics: Alkanes; Androgens; Androsterone; Azo Compounds; Biological Transport; Cholesterol; Chromatography, Thin Layer; Dehydroepiandrosterone; Dihydrotestosterone; Egg Yolk; Female; Indicators and Reagents; Kinetics; Membranes, Artificial; Phosphatidylcholines; Pregnenolone; Progesterone; Progestins; Solubility; Spectrophotometry; Spectrophotometry, Ultraviolet; Testosterone | 1973 |
Steroid metabolism by an oestrogen-dependent interstitial-cell tumour of a rat testis.
Topics: Androstenedione; Androstenes; Androsterone; Animals; Carbon Radioisotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Etiocholanolone; In Vitro Techniques; Leydig Cell Tumor; Male; Pregnenolone; Rats; Steroids; Testicular Neoplasms; Testosterone | 1973 |
In vitro metabolism of (4-14C) pregnenolone in the ovaries of intact and HPL or HCG treated rats.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Animals; Carbon Radioisotopes; Chorionic Gonadotropin; Chromatography, Paper; Dehydroepiandrosterone; Drug Synergism; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hypophysectomy; Ovary; Placental Lactogen; Pregnenolone; Progesterone; Rats; Steroids; Testosterone | 1973 |
Endogenous steroid sulphates and glucuronides in the gallbladder bile from early and mid-term human foetuses.
Topics: 17-alpha-Hydroxypregnenolone; Androstenes; Bile; Chromatography, Gas; Dehydroepiandrosterone; Female; Fetus; Gallbladder; Glucuronates; Humans; Mass Spectrometry; Pregnancy; Pregnanediol; Pregnanetriol; Pregnenolone; Steroids; Sulfates | 1973 |
Steroid metabolism in vitro by an interstitial cell tumour and the attached prepubertal testis.
Topics: Adolescent; Androstenedione; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Leydig Cell Tumor; Male; Pregnenolone; Progesterone; Puberty; Steroids; Testicular Neoplasms; Testis; Testosterone; Tritium | 1973 |
Intracellular distributian and substrate specificity of the 16 alpha-hydroxylase in the adrenal of human fetus.
Topics: Adrenal Glands; Androstenedione; Carbon Radioisotopes; Cell Nucleus; Chromatography, Paper; Chromatography, Thin Layer; Cytosol; Dehydroepiandrosterone; Female; Fetus; Humans; Microsomes; Mitochondria; Pregnancy; Pregnenolone; Progesterone; Steroid Hydroxylases; Subcellular Fractions; Tritium | 1973 |
Formation of neutral steroids from endogenous precursors in minced human fetal adrenals in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Cholesterol; Chromatography, Gas; Chromatography, Gel; Dehydroepiandrosterone; Female; Fetus; Humans; Mass Spectrometry; Pregnancy; Pregnenolone; Progesterone; Steroids; Sulfuric Acids; Time Factors | 1974 |
Steroid metabolism in human and boar testis tissue. Steroid concentrations and the position of the sulfate group in steroid sulfates.
Topics: Adult; Androstenedione; Androsterone; Animals; Chromatography, Gas; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Male; Mass Spectrometry; Organ Size; Pregnenes; Pregnenolone; Progesterone; Species Specificity; Steroids; Sulfuric Acids; Swine; Testis; Testosterone | 1974 |
In vitro biotransformation of steroid hormones by human semen.
Topics: Androgens; Androstenedione; Androstenes; Binding Sites; Biotransformation; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; Male; Plasma; Pregnenolone; Semen; Testosterone; Tritium | 1974 |
The in vitro biosynthesis of steroids by the gonad of the mussel (Mytilus edulis).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Bivalvia; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Gonads; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; Ovary; Oxidation-Reduction; Pregnenolone; Progesterone; Radioimmunoassay; Testis; Testosterone; Tritium | 1974 |
Purification and properties of the delta 5-3 beta-hydroxysteroid dehydrogenase-isomerase system of sheep adrenal cortical microsomes.
Topics: Acetates; Adrenal Glands; Amino Acid Sequence; Amino Acids; Animals; Cell-Free System; Chromatography, Gel; Chromatography, Ion Exchange; Dehydroepiandrosterone; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Isomerases; Microsomes; Molecular Weight; Multienzyme Complexes; Pregnenolone; Sheep; Sodium Dodecyl Sulfate; Surface-Active Agents; Tritium | 1974 |
Gonadal steroid sulfates and sulfatase. VI. Comparative metabolism in isolated seminiferous tubules and minces of human testis.
Topics: Carbon Isotopes; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Lyases; Male; Middle Aged; Mixed Function Oxygenases; Oxidoreductases; Pregnenolone; Sulfatases; Sulfates; Testis; Testosterone; Tritium | 1973 |
The annual testicular cycle and androgen production in vitro in the masked civet cat, Paguma l. larvata.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Carnivora; Dehydroepiandrosterone; Histocytochemistry; Hydroxyprogesterones; In Vitro Techniques; Lipids; Male; Organ Size; Pregnenolone; Progesterone; Seasons; Spermatogenesis; Testis; Testosterone | 1974 |
Steroid excretion and metabolism by gonadal tissue from a subject with testicular feminization syndrome.
Topics: Adolescent; Androgen-Insensitivity Syndrome; Androsterone; Carbon Radioisotopes; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Genitalia; Gonadal Steroid Hormones; Gonads; Humans; Karyotyping; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Sertoli Cells; Testis; Testosterone; Tritium; Vas Deferens | 1974 |
Augmentation of the rat uterine weight response to human chorionic gonadotrophin by various steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Androsterone; Animals; Body Weight; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Organ Size; Ovary; Pregnenolone; Progesterone; Rats; Stimulation, Chemical; Testosterone; Uterus | 1974 |
Biosynthesis of steroids from (14C)cholesterol, (3H) progesterone and (3H)pregnenolone by human adrenal carcinoma tissue.
Topics: Adrenal Gland Neoplasms; Androstenedione; Carbon Radioisotopes; Carcinoma; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Isotope Labeling; Middle Aged; Pregnenolone; Progesterone; Steroids; Tritium; Virilism | 1974 |
The biosynthesis of estrogens by cow follicles.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Biotransformation; Cattle; Cells, Cultured; Chromatography; Dehydroepiandrosterone; Estrogens; Female; Manometry; Ovarian Follicle; Pregnenolone; Progesterone; Tritium | 1974 |
Effect of maternal intrahepatic cholestasis on fetal steroid metabolism.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Androsterone; Birth Weight; Cholestasis; Dehydroepiandrosterone; Estriol; Female; Fetus; Gestational Age; Humans; Hydroxylation; Male; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnanetriol; Pregnenolone; Progesterone; Steroids; Umbilical Cord | 1974 |
Simultaneous estimation of pregnenolone, 17-hydroxypregnenolone and dehydroepiandrosterone by gas-liquid radiochromatography.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carbon Radioisotopes; Chromatography, Gas; Dehydroepiandrosterone; Evaluation Studies as Topic; Female; Humans; Methods; Microsomes; Pregnenolone; Tritium | 1974 |
[Toxicological characteristics of semiproducts of steroid hormones].
Topics: Acetates; Animals; Dehydroepiandrosterone; Drug Industry; Female; Guinea Pigs; Humans; Injections, Intraperitoneal; Male; Mice; Occupational Diseases; Pregnenolone; Rabbits; Rats; Skin; Skin Absorption | 1974 |
New potent inhibitors of 3beta-hydroxy-delta 5-steroid oxidoreductase with short duration of action.
Topics: Androstenedione; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Microsomes; Pregnenolone; Progesterone; Testis; Testosterone; Time Factors; Tritium | 1974 |
Biochemical and clinical observations a pregnancy with placental sulphatase and other enzyme deficiencies.
Topics: 17-Ketosteroids; Adult; Carbon Radioisotopes; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Isomerases; Kinetics; Labor, Induced; Muscle Contraction; Placenta; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnenolone; Progesterone; Prostaglandins; Sulfatases; Sulfuric Acids; Time Factors; Tritium; Uterus | 1974 |
Testicular function in myotonic dystrophy of childhood.
Topics: Androstenedione; Autopsy; Biopsy; Carbon Radioisotopes; Child; Child, Preschool; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Infant; Isotope Labeling; Lyases; Male; Myotonic Dystrophy; Oxidoreductases; Pregnenolone; Steroid Hydroxylases; Testis; Testosterone; Tritium | 1974 |
Endocrine and metabolic studies in an XY patient with gonadal agenesis.
Topics: Adolescent; Adrenal Glands; Amenorrhea; Androstenedione; Dehydroepiandrosterone; Estradiol; Ethinyl Estradiol; Feedback; Female; Follicle Stimulating Hormone; Gonads; Humans; Hydrocortisone; Iodine Radioisotopes; Karyotyping; Luteinizing Hormone; Methyl Ethers; Mullerian Ducts; Phenotype; Pituitary Gland; Pregnenolone; Progesterone; Radioimmunoassay; Sex Chromatin; Sex Chromosomes; Testosterone; Tritium; Turner Syndrome; Wolffian Ducts | 1974 |
Studies on the inhibition by 5alpha-pregnane-3,20-dione of the biosynthesis of 16-androstenes and dehydroepiandrosterone in boar testis preparations.
Topics: 17-alpha-Hydroxypregnenolone; Androstadienes; Androstenes; Animals; Carbon Radioisotopes; Cell Fractionation; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Drug Stability; Freezing; Kinetics; Male; Microsomes; Oxidoreductases; Pregnenolone; Progesterone; Swine; Testis; Ultracentrifugation | 1974 |
Proceedings: Pregnenolone metabolism in patients with carcinoma.
Topics: Breast Neoplasms; Carcinoma; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Metabolic Clearance Rate; Pregnenolone; Prognosis | 1974 |
Androgen formation from pregnenolone sulfate by the human fetal ovary.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Carbon Radioisotopes; Chromatography, Paper; Dehydroepiandrosterone; Female; Gestational Age; Humans; Liver; Ovary; Pregnenolone; Tritium | 1974 |
Tumors of dysgenetic gonads (gonadoblastoma): ultrastructural and steroidogenic aspects.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Androstenes; Basement Membrane; Cell Nucleus; Cytoplasm; Dehydroepiandrosterone; Dysgerminoma; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; In Vitro Techniques; Pregnenolone; Progesterone; Testosterone; Turner Syndrome | 1974 |
[Histoenzymology of the ovary of the pregnant and non-pregnant cat: importance of interstitial tissue].
Topics: 17-alpha-Hydroxypregnenolone; Animals; Cats; Corpus Luteum; Dehydroepiandrosterone; Estradiol; Female; Hydroxysteroid Dehydrogenases; Ovary; Pregnancy; Pregnenolone; Progesterone; Succinate Dehydrogenase; Testosterone; Time Factors | 1973 |
Steroid hormone production by sheep ovarian follicles cultured in vitro.
Topics: Androstenediols; Androstenedione; Animals; Biometry; Cells, Cultured; Chromatography, Thin Layer; Dehydroepiandrosterone; Estrogens; Female; In Vitro Techniques; Organ Size; Ovarian Follicle; Pregnanediol; Pregnanetriol; Pregnenolone; Progesterone; Protein Binding; Sheep; Steroids; Testosterone; Time Factors; Tritium | 1974 |
[Appearance of steroidogenesis in the cat ovary: histoenzymological study].
Topics: Animals; Cats; Cell Differentiation; Dehydroepiandrosterone; Female; Histocytochemistry; Hydroxysteroid Dehydrogenases; Ovary; Pregnenolone; Steroids | 1974 |
[Determination of methyltestosterone, methylandrostenediol, dehydroepiandrosterone acetate and dehydropregnenolone acetate in skin washings].
Topics: Acetates; Anabolic Agents; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Methandriol; Methyltestosterone; Pregnenolone; Skin | 1974 |
Estrogen synthesis by the pregnant baboon.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Oxidoreductases; Papio; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Sulfatases; Tritium | 1972 |
Steroid hydroxylations. V. Intracellular location of 16alpha-hydroxylase and its substrate specificity in sow ovary.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Chromatography, Paper; Dehydroepiandrosterone; Female; Hydroxyprogesterones; In Vitro Techniques; Mixed Function Oxygenases; Ovary; Periodic Acid; Pregnenolone; Progesterone; Swine; Testosterone | 1966 |
Androgen synthesis in a patient with virilizing adrenocortical carcinoma.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Carbon Isotopes; Chromatography; Culture Techniques; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone | 1967 |
Quantitative gas chromatography of adrenal cortical steroids.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Aldosterone; Androsterone; Chemical Phenomena; Chemistry; Cholesterol; Chromatography, Gas; Computers; Corticosterone; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Hydroxyprogesterones; Methods; Periodic Acid; Pregnenolone; Progesterone | 1968 |
A virilizing adrenal tumor with borderline elevation of urinary 17-ketosteroids.
Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Androgens; Androsterone; Child; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Steroids; Testosterone | 1968 |
Inhibition of adrenal cortical secretion by amino-glutethimide in dogs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Chromatography, Paper; Corticosterone; Dehydroepiandrosterone; Depression, Chemical; Desoxycorticosterone; Dogs; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Pyridones; Veins | 1968 |
Diurnal variation in the concentrations of solvolyzable steroids in human plasma.
Topics: 17-Hydroxycorticosteroids; Acetates; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstanes; Androsterone; Circadian Rhythm; Dehydroepiandrosterone; Humans; Male; Plasma; Pregnanes; Pregnenolone; Sterols; Sulfates; Sulfuric Acids | 1968 |
The effect of exogenous corticotrophin on steroid excretion in the newborn.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgens; Chemistry, Clinical; Chromatography, Thin Layer; Dehydroepiandrosterone; Dyspepsia; Feeding and Eating Disorders; Humans; Hydrocortisone; Hyperbilirubinemia; Infant, Newborn; Infant, Premature; Laryngitis; Male; Pregnanes; Pregnenolone; Shock; Stimulation, Chemical | 1968 |
Steroid dehydrogenases and steroids in gonads of the seaperch Cymatogaster aggregata Gibbons.
Topics: Androgens; Androstanes; Androsterone; Animals; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Fishes; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cells; Male; NAD; Oxidoreductases; Pregnenolone; Progesterone; Seasons; Sertoli Cells; Steroids; Testosterone | 1969 |
The delta5-3beta-hydroxysteroid dehydrogenase of bovine adrenal microsomes.
Topics: Acetone; Adrenal Glands; Animals; Cattle; Chromatography, Gas; Dehydroepiandrosterone; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; NAD; Pregnenolone; Spectrum Analysis; Tissue Extracts | 1969 |
Effect of ethanol metabolism on redox state of steroid sulphates in man.
Topics: 17-Ketosteroids; Adult; Androstanes; Chromatography, Gas; Computers; Dehydroepiandrosterone; Depression, Chemical; Deuterium; Ethanol; Humans; Liver; Male; NAD; Oxidation-Reduction; Pregnanes; Pregnenolone; Silicon; Spectrum Analysis; Steroids; Stimulation, Chemical; Sulfuric Acids; Time Factors | 1970 |
Neutral steroids in urine during pregnancy. I. Isolation and identification of dihydroxylated C19 and C21 steroid disulphates.
Topics: Androstanes; Androsterone; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Humans; Male; Pregnancy; Pregnanediol; Pregnanes; Pregnenolone; Silicon Dioxide; Spectrum Analysis; Sulfates | 1970 |
Cushing's syndrome caused by malignant tumor in the scrotum: clinical, pathologic and biochemical studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Rest Tumor; Adrenocorticotropic Hormone; Androstanes; Autopsy; Chromatography; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone; Dexamethasone; Edema; Humans; Hydrocortisone; Hypokalemia; Male; Metyrapone; Middle Aged; Mixed Function Oxygenases; Neoplasm Metastasis; Pregnanes; Pregnenolone; Progesterone; Retroperitoneal Neoplasms; Scrotum; Tritium | 1971 |
Inhibition of steroid 3-sulfatase by endogenous steroids. A possible mechanism controlling placental estrogen synthesis from conjugated precursors.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Endoplasmic Reticulum; Estriol; Estrogens; Feedback; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Sterols; Sulfatases; Sulfates; Tritium | 1970 |
Characteristics of the formation and conversion of androgenic hormones in the rat adrenal gland.
Topics: Adenosine Triphosphate; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Gonadotropins; Hydroxysteroid Dehydrogenases; Isomerases; Male; Metyrapone; Pregnenolone; Progesterone; Rats; Testosterone | 1971 |
Possible role of cyclic AMP in the short term regulation of adrenal steroidogenesis.
Topics: 17-alpha-Hydroxypregnenolone; Adenine Nucleotides; Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Animals; Cholesterol; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Steroids | 1971 |
Gonadal steroid sulfates and sulfatase. 3. Correlation of human testicular sulfatase, 3beta-hydroxysteroid dehydrogenase-isomerase, histologic structure and serum testosterone.
Topics: 17-Hydroxycorticosteroids; Androstanes; Carbon Isotopes; Chromatography, Paper; Dehydroepiandrosterone; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Leydig Cells; Male; Microsomes; NAD; Pregnenolone; Progesterone; Steroids; Sterols; Sulfatases; Sulfates; Testis; Testosterone; Tritium | 1971 |
The effect of adenosine 3',5'-monophosphate and of N 6 -2'-O-dibutyryl-adenosine 3',5'-monophosphate on the mouse ovarian 5 -3 -hydroxysteroid dehydrogenase.
Topics: 17-Ketosteroids; Androstanes; Animals; Butyrates; Chorionic Gonadotropin; Chromatography, Thin Layer; Cyclic AMP; Dehydroepiandrosterone; Depression, Chemical; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Ketosteroids; Metabolism; Mice; NAD; Ovary; Pregnenolone; Progesterone; Stimulation, Chemical; Tritium | 1971 |
Biosynthesis and secretion of steroids by the canine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Chorionic Gonadotropin; Cyclic AMP; Dehydroepiandrosterone; Dogs; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Steroids; Testis; Testosterone; Tritium | 1971 |
A technique for the assay of 17-hydroxyprogesterone (17-hydroxy-4-pregnene-3,20-dione) in serum using celite column chromatography and competitive protein binding.
Topics: 17-Ketosteroids; Acetates; Acylation; Alcohols; Androstanes; Anhydrides; Chemical Phenomena; Chemistry; Cholesterol; Chromatography; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estriol; Estrone; Female; Gonadotropins; Humans; Hydroxyprogesterones; Infertility, Female; Male; Menopause; Methods; Pregnenolone; Progesterone; Protein Binding; Silicon Dioxide; Testosterone; Transcortin; Tritium | 1971 |
Plasma steroids in two subjects with ovarian androgen-producing tumors arrhenoblastoma and gynandroblastoma.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Dexamethasone; Diagnosis, Differential; Female; Glucocorticoids; Humans; Mass Spectrometry; Middle Aged; Neoplasms, Gonadal Tissue; Ovarian Neoplasms; Pregnanetriol; Pregnenolone; Sertoli-Leydig Cell Tumor; Testosterone | 1972 |
3Beta-hydroxysteroid dehydrogenase activity in the adrenals of normal and hypophysectomized chick embryos. 1.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Chick Embryo; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Hypophysectomy; Pituitary Gland; Pregnenolone; Time Factors; Transplantation, Homologous | 1972 |
Model studies with erythrocytes on the initial steps of cellular uptake and binding of steroids.
Topics: 17-Ketosteroids; Androstenes; Biological Transport; Blood Proteins; Cell Membrane; Dehydroepiandrosterone; Dialysis; Erythrocytes; Estrone; Humans; Hydroxysteroid Dehydrogenases; Isomerism; Ketosteroids; Mathematics; Permeability; Pregnenolone; Progesterone; Protein Binding; Receptors, Cell Surface; Steroids; Sulfuric Acids; Testosterone; Tritium | 1972 |
Steroid metabolism in the adrenals of fetal sheep in relation to natural and corticotrophin-induced parturition.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Dehydroepiandrosterone; Desoxycorticosterone; Female; Fetus; Hydrocortisone; Labor, Induced; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Sheep; Steroid Hydroxylases; Sulfates; Tritium; Umbilical Arteries; Umbilical Veins | 1972 |
Microbial transformation of cholesterol into coprostanol. Properties of a 3-oxo- 4-steroid-5 beta-reductase.
Topics: Ammonium Sulfate; Animals; Carbon Isotopes; Cecum; Chemical Precipitation; Chloromercuribenzoates; Cholestanes; Cholestenes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Enterobacteriaceae; Feces; Ketosteroids; NAD; Oxidoreductases; Pregnenolone; Progesterone; Rats; Structure-Activity Relationship; Testosterone | 1973 |
Biosynthesis of steroids from cholesterol-14C by human adrenal carcinoma tissue.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androstenedione; Bucladesine; Carbon Radioisotopes; Carcinoma; Cholesterol; Chromatography; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Phenols; Pregnenolone; Progesterone; Testosterone; Tritium | 1973 |
The biogenesis and metabolism of steroids in the human placenta of 9--14 weeks in vitro.
Topics: Acetates; Carbon Radioisotopes; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Culture Techniques; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Mass Spectrometry; Methods; NAD; Placenta; Pregnancy; Pregnenolone; Progesterone; Sodium; Steroids; Testosterone; Time Factors | 1973 |
Steroid biosynthesis by transplantable gonadal tumors of rat.
Topics: 17-alpha-Hydroxypregnenolone; Acetates; Androstenedione; Animals; Bucladesine; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Granulosa Cell Tumor; Hydroxyprogesterones; Luteinizing Hormone; Male; Neoplasm Transplantation; Ovarian Neoplasms; Pregnenolone; Progesterone; Rats; Spectrophotometry, Ultraviolet; Testicular Neoplasms; Testosterone; Transplantation, Homologous; Tritium | 1973 |
Stimulating effect of crystalline cholesterol on spermiogenesis and oxidative activity in the senile rat testicle.
Topics: Aging; Androsterone; Animals; Cholesterol; Crystallization; Dehydroepiandrosterone; Dihydrolipoamide Dehydrogenase; Electron Transport Complex IV; Estradiol; Glucosephosphate Dehydrogenase; Histocytochemistry; Hydrocortisone; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Rats; Spermatogenesis; Stimulation, Chemical; Succinate Dehydrogenase; Testis; Testosterone | 1973 |
[Biosynthesis of steroids by human adrenal cancer tissue--effects of ACTH and cyclic AMP].
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Androstenedione; Carbon Radioisotopes; Cholesterol; Chromatography, Paper; Cyclic AMP; Dehydroepiandrosterone; Female; Glucocorticoids; Humans; Hydroxyprogesterones; In Vitro Techniques; Middle Aged; Pregnenolone; Progesterone; Tritium | 1974 |
[Urinary excretion of total estrogens after administration of ACTH to pregnant women in the 3d trimester].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Estrogens; Female; Humans; Pregnancy; Pregnancy Trimester, Third; Pregnenolone | 1973 |
Stimulation of the rat ovary by gonadotropins and separation of steroids by gas chromatography.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Cholesterol; Chorionic Gonadotropin; Chromatography, Gas; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Gonadotropins, Equine; Hydroxyprogesterones; In Vitro Techniques; Luteinizing Hormone; NADP; Nandrolone; Ovary; Pregnenolone; Progesterone; Rats; Subcellular Fractions; Testosterone | 1965 |
Production and utilization of reduced nicotinamide adenine dinucleotide phosphate in the mouse testis.
Topics: Animals; Cholesterol; Dehydroepiandrosterone; Enzymes; Glucosephosphate Dehydrogenase; Histocytochemistry; In Vitro Techniques; Isocitrate Dehydrogenase; Leydig Cells; Male; Mice; NADP; Oxidoreductases; Pregnenolone; Subcellular Fractions; Testis; Testosterone | 1965 |
Dehydrogenase in the rat ovary. I. A histochemical study of delta-5-3-beta-and 20-alpha-hydroxysteroid dehydrogenases and enzymes of carbohydrate oxidation during the estrous cycle.
Topics: Animals; Dehydroepiandrosterone; Estrus; Female; Glucosephosphate Dehydrogenase; Histocytochemistry; Hydroxysteroid Dehydrogenases; L-Lactate Dehydrogenase; NAD; NADP; Ovary; Oxidoreductases; Pregnancy; Pregnenolone; Rats; Succinate Dehydrogenase; Tetrazolium Salts | 1966 |
Stimulation of cholesterol metabolism in the luteinized rat ovary by luteinizing hormone.
Topics: Androgens; Animals; Cholesterol; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; Luteinizing Hormone; NADP; Ovary; Pregnenolone; Progesterone; Rats | 1966 |
Conversion of 17-alpha-hydroxypregnenolone to dehydroepiandrosterone by adrenal homogenates of immature and adult guinea pigs.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Aging; Animals; Animals, Newborn; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dehydroepiandrosterone; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; NADP; Pregnenolone; Tritium | 1967 |
Histochemical distribution of some hydroxysteroid dehydrogenases in the placenta, foetal membranes and uterine mucosa of the mouse.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Dehydroepiandrosterone; Endometrium; Estradiol; Extraembryonic Membranes; Female; Histocytochemistry; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Mice; NAD; NADP; Placenta; Pregnancy; Pregnancy, Animal; Pregnenolone; Testosterone | 1968 |
Androgen production in vitro by phalarope gonadal tissue homogenates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Animals; Birds; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Male; NADP; Ovary; Pregnanes; Pregnenolone; Testis; Testosterone; Tritium | 1968 |
Androgen biosynthesis. I. Enzymatic cleavage of the cholesterol side-chain to dehydroepiandrosterone and 2-methylheptan-6-one.
Topics: Adrenal Glands; Androgens; Animals; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Fatty Acids; Female; Ketones; Male; Methods; NADP; Ovary; Pregnenolone; Rats; Testis; Tritium | 1968 |
The effect of NADPH on steroidogenesis by the human adrenal gland in vivo.
Topics: Adrenal Glands; Adrenalectomy; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; NADP; Neoplasm Metastasis; Pregnenolone; Tritium | 1969 |
The effect of exogenous human chorionic gonadotrophin on steroid excretion in the newborn.
Topics: 17-Ketosteroids; Chemistry, Clinical; Chorionic Gonadotropin; Chromatography, Gas; Cryptorchidism; Dehydroepiandrosterone; Humans; Infant, Newborn; Male; Pregnanes; Pregnenolone; Stimulation, Chemical | 1969 |
Effect of diethylstilbestrol on enzymes of cryptochid mouse testes of Balb-c mice.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Animals; Cryptorchidism; Dehydroepiandrosterone; Depression, Chemical; Diethylstilbestrol; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Leydig Cells; Lyases; Male; Mice; Microsomes; Mixed Function Oxygenases; Pregnenolone; Progesterone; Testis; Testosterone | 1969 |
Steroid biosynthesis by the equine testis.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Age Factors; Androstanes; Animals; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Haplorhini; Horses; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Leydig Cells; Lyases; Male; Mice; Mixed Function Oxygenases; NADP; Physiology, Comparative; Pregnenolone; Testis; Testosterone; Tritium | 1969 |
On the specificity of steroid interaction with mammary glucose 6-phosphate dehydrogenase.
Topics: Androstanes; Animals; Binding Sites; Dehydroepiandrosterone; Estranes; Female; Glucosephosphate Dehydrogenase; Humans; Hydrogen-Ion Concentration; Kinetics; Lactation; Mammary Glands, Animal; Models, Chemical; NADP; Pregnancy; Pregnenolone; Protein Binding; Rats; Steroids | 1970 |
Hexose-6-phosphate dehydrogenase: distribution in rat tissues and effect of diet, age and steroids.
Topics: Adrenal Glands; Age Factors; Alcohol Oxidoreductases; Androstanes; Animals; Brain; Dehydroepiandrosterone; Dietary Carbohydrates; Female; Fetus; Fructose; Galactose; Glucose; Glucosephosphate Dehydrogenase; Hexosephosphates; Intestines; Kidney; Liver; Lung; Male; Mammary Glands, Animal; Microsomes; Microsomes, Liver; Muscles; Myocardium; NAD; NADP; Ovary; Pregnancy; Pregnanes; Pregnenolone; Progesterone; Prostate; Rats; Seminal Vesicles; Spleen; Steroids; Testis | 1970 |
Steroidogenesis in post- and pre-spawned ovaries of a cichlid fish, Tilapia aurea.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Animals; Chromatography, Gas; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Ovary; Ovulation; Pregnenolone; Progesterone; Steroids; Testosterone; Tritium | 1971 |
Human placental hydroxylation of 3,4-benzpyrene during early gestation and at term.
Topics: 17-Ketosteroids; Androstanes; Animals; Benzopyrenes; Cholesterol; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Fluorometry; Humans; Kinetics; Labor, Obstetric; Liver; Methylcholanthrene; Methyltestosterone; Mixed Function Oxygenases; NADP; Placenta; Pregnancy; Pregnenolone; Progesterone; Rats; Smoking; Testosterone | 1971 |
Effects of pinealectomy on the testicular function of the adult male duck.
Topics: 17-alpha-Hydroxypregnenolone; Analysis of Variance; Androstanes; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Ducks; Hydroxyprogesterones; Male; NADP; Organ Size; Pineal Gland; Pregnenolone; Progesterone; Progestins; Seasons; Testis; Testosterone | 1971 |
3 -Hydroxy steroid dehydrogenase activity in the mitochondria of rat adrenal homogenates.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Cell Fractionation; Centrifugation; Dehydroepiandrosterone; Electron Transport Complex IV; Female; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kinetics; Male; Microsomes; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Pregnenolone; Rats; RNA; Tritium | 1971 |
[Significance of chorionic gonadotropin participating in biosynthesis of estrogens in placental chorionic tissue].
Topics: Androstanes; Chorionic Gonadotropin; Chromatography; Colorimetry; Cyclic AMP; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Extraembryonic Membranes; Female; Humans; NAD; NADP; Placenta; Pregnancy; Pregnenolone; Progesterone; Stimulation, Chemical; Testosterone; Tritium | 1972 |
The metabolism of 16-androstenes in boar salivary glands.
Topics: Androstanes; Androstenols; Animals; Carbon Isotopes; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Ketosteroids; Models, Biological; NAD; NADP; Parotid Gland; Pregnenolone; Saliva; Submandibular Gland; Testosterone; Tritium | 1972 |
Metabolism of 3 -hydroxy- 5 - and 3-oxo- 4 -C 19 and C 21 steroids in human liver microsomes.
Topics: Adult; Aged; Androstenes; Androsterone; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Culture Media; Dehydroepiandrosterone; Female; Humans; Male; Mass Spectrometry; Methods; Microsomes, Liver; Middle Aged; NAD; NADP; Pregnenolone; Progesterone; Sex Factors; Steroids; Testosterone; Time Factors | 1972 |
Some aspects of the control of dehydroepiandrosterone synthesis in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstanols; Carbon Isotopes; Chromatography, Paper; Cyproterone; Dehydroepiandrosterone; Female; Humans; Hydroxylation; In Vitro Techniques; Kinetics; NADP; Pregnenolone; Subcellular Fractions | 1972 |
Pathways for androgen synthesis in vitro by the testes of Japanese quail (Coturnix coturnix japonica).
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Androstanes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Coturnix; Dehydroepiandrosterone; Hydroxyprogesterones; In Vitro Techniques; Male; NAD; NADP; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1972 |
Steroid 16 alpha-hydroxylase from human fetal liver; inhibition by steroids.
Topics: 17-alpha-Hydroxypregnenolone; Androstenediols; Androstenols; Aryl Hydrocarbon Hydroxylases; Chlormadinone Acetate; Dehydroepiandrosterone; Estradiol; Estrone; Ethinyl Estradiol; Humans; Liver; Mestranol; Norethindrone; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1980 |
[Luteotropic effect of human chorionic gonadotropin on human corpus luteum in early gestation (author's transl)].
Topics: Chorionic Gonadotropin; Corpus Luteum; Dehydroepiandrosterone; Female; Humans; Ovary; Pregnancy; Pregnancy Trimester, First; Pregnenolone; Progesterone | 1982 |
Effect of photoperiod on the testicular steroidogenesis of the bank vole (Clethrionomys glareolus, Schreber): an in vitro study.
Topics: Animals; Arvicolinae; Dehydroepiandrosterone; Gonadal Steroid Hormones; In Vitro Techniques; Light; Male; Organ Size; Pregnenolone; Testis | 1982 |
Sterol sulfate metabolism in the adrenals of the human fetus, anencephalic newborn, and adult.
Topics: Adolescent; Adrenal Glands; Adult; Anencephaly; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cytosol; Dehydroepiandrosterone; Fetus; Humans; Infant, Newborn; Male; Microsomes; Mitochondria; Pregnenolone; Sterols; Sulfates; Sulfotransferases; Sulfurtransferases | 1982 |
Norethisterone does not inhibit rat testis delta 5-3 beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cyanoketone; Dehydroepiandrosterone; Diethylstilbestrol; In Vitro Techniques; Kinetics; Male; Norethindrone; Pregnenolone; Rats; Rats, Inbred Strains; Substrate Specificity; Testis | 1982 |
Local modulation of progesterone production in human fetal membranes.
Topics: Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Extraembryonic Membranes; Female; Humans; In Vitro Techniques; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone | 1982 |
Biosynthesis of 3 beta-hydroxy-5,7-pregnadien-20-one by the horse fetal gonad.
Topics: Animals; Dehydroepiandrosterone; Equilin; Gonads; Horses; In Vitro Techniques; Pregnadienes; Pregnenolone | 1983 |
Pregnenolone and its sulfate ester in the rat brain.
Topics: Animals; Brain; Brain Chemistry; Dehydroepiandrosterone; Kinetics; Male; Pregnenolone; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1983 |
On some useful statistical techniques in the analysis of hormone data.
Topics: Analysis of Variance; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Hormones; Humans; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Statistics as Topic; Steroids | 1983 |
Properties of porcine liver and testicular steroid sulphotransferases: reaction conditions and influence of naturally occurring steroids and steroid sulphates.
Topics: Androstenols; Animals; Dehydroepiandrosterone; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Pregnenolone; Sulfates; Sulfurtransferases; Swine; Testis | 1983 |
Formation and isolation of delta 5-3-ketosteroids using a purified rat liver alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Dehydroepiandrosterone; Ketosteroids; Kinetics; Liver; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Pregnenolone; Rats | 1982 |
Inhibition of 3-beta-hydroxy steroid dehydrogenase activity in first trimester human pregnancy with trilostane and WIN 32729.
Topics: 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents; Abortifacient Agents, Steroidal; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Pregnancy; Pregnancy Trimester, First; Pregnenolone; Progesterone | 1983 |
Testicular steroid metabolism in juvenile bank voles (Clethrionomys glareolus Schreber) exposed to different photoperiods: an in vitro study.
Topics: Androgens; Animals; Arvicolinae; Chromatography, Thin Layer; Dehydroepiandrosterone; Light; Male; Periodicity; Pregnenolone; Progesterone; Testis | 1983 |
[Sequential changes of serum steroid levels in puerperium].
Topics: Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Postpartum Period; Pregnancy; Pregnenolone; Radioimmunoassay | 1983 |
Benign premature adrenarche: clinical features and serum steroid levels.
Topics: 17-alpha-Hydroxyprogesterone; Acne Vulgaris; Adrenal Glands; Androgens; Androstenedione; Child; Child, Preschool; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone | 1983 |
Testicular steroidogenesis in the camel (Camelus dromedarius) during the mating and the nonmating seasons.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenediols; Androstenedione; Animals; Camelus; Dehydroepiandrosterone; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Progesterone; Sexual Behavior, Animal; Steroid Hydroxylases; Testis; Testosterone | 1983 |
[Changes in plasma concentrations of adrenal androgens in patients with chronic renal insufficiency].
Topics: Adrenal Glands; Adult; Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Kidney Failure, Chronic; Male; Middle Aged; Pregnenolone | 1983 |
Studies on the poll glands of the one-humped camel in relation to reproductive activity. I. Seasonal morphological and histochemical changes.
Topics: Animals; Camelus; Castration; Dehydroepiandrosterone; Exocrine Glands; Glycogen; Glycoproteins; Histocytochemistry; Hydroxysteroid Dehydrogenases; Male; Pregnenolone; Reproduction; Scent Glands; Seasons; Sex Attractants; Testosterone | 1984 |
Ovarian steroid metabolism and oestrogens in the corpus luteum of the tammar wallaby.
Topics: Androstenedione; Animals; Aromatase; Corpus Luteum; Dehydroepiandrosterone; Embryo Implantation, Delayed; Estradiol; Estrone; Female; Macropodidae; Marsupialia; Ovary; Pregnancy; Pregnancy, Animal; Pregnenolone | 1984 |
Steroid concentrations in the outer and inner zones of the adrenal cortex of the guinea pig.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Androstenedione; Animals; Dehydroepiandrosterone; Guinea Pigs; Male; Pregnenediones; Pregnenes; Pregnenolone; Tissue Distribution | 1984 |
Umbilical artery concentrations of androstenedione increased in early labour in the leading twin fetus.
Topics: Androstenedione; Cesarean Section; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Labor Stage, First; Labor Stage, Second; Labor, Obstetric; Pregnancy; Pregnenolone; Progesterone; Twins | 1984 |
Modifications in the testis steroidogenic pathways in rats fed with cottonseed flour.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Androgens; Animals; Cottonseed Oil; Dehydroepiandrosterone; Diet; Gossypol; Hydroxyprogesterones; Male; Mice; Mice, Inbred Strains; Pregnenolone; Rats; Testis; Testosterone | 1984 |
Genetic regulation of hepatic steroid 16 alpha-hydroxylase activities in inbred strains of mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dehydroepiandrosterone; Female; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred Strains; Pregnenolone; Progesterone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Testosterone | 1984 |
Norethisterone and ethinylestradiol do not inhibit delta 5-3 beta-hydroxysteroid dehydrogenase in rat Leydig cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cyanoketone; Dehydroepiandrosterone; Ethinyl Estradiol; Kinetics; Leydig Cells; Male; Norethindrone; Norethindrone Acetate; Pregnenolone; Rats; Rats, Inbred Strains | 1984 |
Adrenal androgens in obese boys before and after weight loss.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Androgens; Androstenedione; Body Weight; Child; Dehydroepiandrosterone; Estradiol; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Obesity; Pregnenolone; Progesterone; Testosterone | 1984 |
[Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Blood Specimen Collection; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Fetal Blood; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Prenatal Diagnosis | 1984 |
Enhancement of human amniotic phospholipase A2 activity by steroid-sulphate derived from the foeto-placental unit.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Cholesterol Esters; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2; Pregnancy; Pregnenolone; Progesterone | 1984 |
Steroid metabolism in corpora lutea of the western spotted skunk (Spilogale putorius latifrons).
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 20-alpha-Dihydroprogesterone; Androstenedione; Animals; Carnivora; Corpus Luteum; Dehydroepiandrosterone; Embryo Implantation, Delayed; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Hydroxyprogesterones; Mephitidae; Pregnancy; Pregnenolone; Progesterone; Testosterone | 1984 |
Early steroid metabolism by chick blastoderm in vitro.
Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Blastoderm; Chick Embryo; Dehydroepiandrosterone; Estradiol; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Steroids; Testosterone | 1984 |
Significance of the delta 5 and delta 4 steroidogenic pathways in the hamster preovulatory follicle.
Topics: Androstenedione; Animals; Cricetinae; Dehydroepiandrosterone; Dihydrotestosterone; Female; Granulosa Cells; In Vitro Techniques; Luteinizing Hormone; Mesocricetus; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Testosterone; Theca Cells; Time Factors | 1983 |
Abnormal adrenal responses to adrenocorticotropic hormone in hyperandrogenic women.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydroxyprogesterones; Pregnenolone; Testosterone; Time Factors | 1980 |
Inhibition of adrenal steroidogenesis by danazol in vivo.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Cortodoxone; Danazol; Dehydroepiandrosterone; Female; Humans; Pregnadienes; Pregnenolone; Progesterone; Steroids; Time Factors | 1980 |
Familial male pseudohermaphroditism due to 17-20-desmolase deficiency. I. In vivo endocrine studies.
Topics: 17-alpha-Hydroxypregnenolone; Adrenocorticotropic Hormone; Aldehyde-Lyases; Androstenedione; Child; Chorionic Gonadotropin; Dehydroepiandrosterone; Dexamethasone; Disorders of Sex Development; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Karyotyping; Male; Menstruation; Pedigree; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone | 1980 |
Regulation of steroid secretion by adrenal tissue of a human anencephalic fetus.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anencephaly; Arginine Vasopressin; Dehydroepiandrosterone; Female; Fetal Diseases; Fetus; Humans; Hydrocortisone; Melanocyte-Stimulating Hormones; Organ Culture Techniques; Pregnancy; Pregnenolone | 1980 |
Subcellular metabolic pools in the rat adrenal gland. In vivo effect of acute stimulation with ACTH on steroid biosynthesis.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Corticosterone; Dehydroepiandrosterone; Hydrocortisone; Hydroxyprogesterones; Male; Microsomes; Mitochondria; Pregnenolone; Progesterone; Rats; Steroids; Subcellular Fractions | 1980 |
In vitro release of steroids from the human fetal adrenal tissue.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Fetus; Hormones; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Progesterone | 1981 |
Studies on ovarian and adrenal studies at different phases of the menstrual cycle. IV. The effect of dexamethasone suppression and subsequent ACTH stimulation at different phases of the menstrual cycle and following the administration of 150 mg of depot-m
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dehydroepiandrosterone; Delayed-Action Preparations; Dexamethasone; Estradiol; Female; Humans; Hydrocortisone; Luteinizing Hormone; Medroxyprogesterone; Medroxyprogesterone Acetate; Menstruation; Ovary; Pregnenolone; Progesterone; Steroids | 1981 |
Adrenocortical function in old age: response to acute adrenocorticotropin stimulation.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aging; Androstenedione; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Male; Middle Aged; Pregnenolone; Progesterone | 1982 |
Time trend analysis of plasma unconjugated and sulfoconjugated estrone and 3 beta-delta 5-steroids in fetal and maternal sheep plasma in relation to spontaneous parturition at term.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrone; Female; Fetal Blood; Gestational Age; Labor, Obstetric; Pregnancy; Pregnancy, Animal; Pregnenolone; Progestins; Sheep; Sulfates | 1982 |
Impaired pregnenolone secretion after combined cyproterone acetate and ethynyl estradiol therapy in hirsute patients.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androstenedione; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Ethinyl Estradiol; Female; Hirsutism; Humans; Hydrocortisone; Hydroxyprogesterones; Pregnenolone; Progesterone; Testosterone | 1982 |
Steroid modulation of pregnenolone to progesterone conversion by human placental cells in vitro.
Topics: Androstenedione; Cells, Cultured; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Estrone; Female; Gonadal Steroid Hormones; Humans; In Vitro Techniques; Infant, Newborn; Microbial Collagenase; Placenta; Pregnancy; Pregnenolone; Progesterone; Steroids; Testosterone | 1983 |
Steroidogenesis in dispersed cells of human fetal adrenal.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cyanoketone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Pituitary Hormones; Pregnenolone; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes | 1983 |
Pattern of plasma pregnenolone sulfate levels in humans from birth to adulthood.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aging; Child; Child, Preschool; Chorionic Gonadotropin; Circadian Rhythm; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Female; Fetal Blood; Humans; Infant; Infant, Newborn; Male; Metyrapone; Middle Aged; Pregnenolone | 1983 |
Effect of prostaglandins on steroid secretion by human fetal adrenal tissue.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Estradiol; Female; Fetus; Humans; Hydrocortisone; In Vitro Techniques; Pregnancy; Pregnenolone; Prostaglandins E; Prostaglandins F; Radioimmunoassay | 1983 |
Excitatory effect of dehydroepiandrosterone, its sulphate ester and pregnenolone sulphate, applied by iontophoresis and pressure, on single neurones in the septo-preoptic area of the guinea pig.
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Guinea Pigs; Membrane Potentials; Neurons; Pregnenolone; Preoptic Area; Septum Pellucidum; Synaptic Transmission | 1984 |
Sexual precocity in a female infant due to feminizing adrenal carcinoma.
Topics: Adrenal Gland Neoplasms; Dehydroepiandrosterone; Female; Follow-Up Studies; Humans; Infant; Karyotyping; Pregnenolone; Puberty, Precocious | 1980 |
Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients.
Topics: Aged; Androstenedione; Androsterone; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Humans; Hydroxyprogesterones; Male; Middle Aged; Organophosphorus Compounds; Pregnenolone; Progesterone; Prostatic Neoplasms; Steroids; Testosterone | 1980 |
The role of low density, high density, and very low density lipoproteins in steroidogenesis by the human fetal adrenal gland.
Topics: Adrenal Glands; Dehydroepiandrosterone; Female; Fetus; Humans; Hydrocortisone; Kinetics; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Organ Culture Techniques; Pregnancy; Pregnenolone | 1980 |
[Radioimmunoassay of dehydroepiandrosterone and 5-androsten-3 beta, 17 beta-diol (author's transl)].
Topics: Androstenediol; Androstenediols; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Humans; Photometry; Pregnenolone; Radioimmunoassay; Testosterone | 1980 |
Biosynthesis of lipoidal derivatives of pregnenolone and dehydroisoandrosterone by the adrenal.
Topics: Adrenal Glands; Animals; Cattle; Dehydroepiandrosterone; Kinetics; Microsomes; Mitochondria; Pregnenolone; Rats; Structure-Activity Relationship; Subcellular Fractions | 1980 |
In-vitro synthesis of androgen from pregnenolone in the testes of the goat (Capra hircus) and identification of 5-pregnene-3beta,17alpha,20alpha-triol as an intermediate in the metabolic pathway of pregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Cell-Free System; Dehydroepiandrosterone; Goats; Hydroxyprogesterones; In Vitro Techniques; Male; Pregnenes; Pregnenolone; Progesterone; Testis; Testosterone | 1980 |
Metabolism of steroids by mouse teratocarcinoma cells.
Topics: Androstenedione; Animals; Cells, Cultured; Dehydroepiandrosterone; Estradiol; Fibroblasts; Kinetics; Mice; Neoplasms, Experimental; Pregnenolone; Progesterone; Steroids; Teratoma | 1980 |
Sex differences in the activity of different cytochrome P450 dependent steroid 16 alpha-hydroxylases in rat liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Female; Liver; Male; Microsomes; Pregnenolone; Progesterone; Rats; Sex Factors; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Testosterone | 1980 |
Serum steroid sulphates in ichthyosis.
Topics: Adolescent; Adult; Androstenediol; Androstenediols; Child; Child, Preschool; Dehydroepiandrosterone; Female; Humans; Ichthyosis; Infant, Newborn; Male; Middle Aged; Pregnenolone; Sulfates | 1980 |
Hormone synthesis by primary breast carcinomas and prognosis in human breast cancer.
Topics: Androgens; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Neoplasm Staging; Pregnenolone; Progesterone; Prognosis; Recurrence | 1980 |
Age-related changes in endogenous steroids of human fetal testis during early and midpregnancy.
Topics: Androstenedione; Dehydroepiandrosterone; Estradiol; Gestational Age; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Male; Pregnenolone; Progesterone; Progestins; Testis; Testosterone | 1981 |
Steroid metabolism in the yolk sac placenta and endometrium of the tammar wallaby, Macropus eugenii.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Endometrium; Estrogens; Female; In Vitro Techniques; Macropodidae; Marsupialia; Organ Size; Pregnancy; Pregnenolone; Progesterone; Testosterone; Yolk Sac | 1980 |
Substrate and nucleotide specificity of placental microsomal 3 beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Dehydroepiandrosterone; Estrogens; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NAD; NADP; Placenta; Pregnancy; Pregnenolone; Steroids; Substrate Specificity | 1981 |
Failure to detect delta 5-3 beta-hydroxysteroid oxidoreductase activity in the preimplantation rabbit embryo.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Blastocyst; Dehydroepiandrosterone; Female; Pregnancy; Pregnenolone; Progesterone Reductase; Rabbits; Radioisotope Dilution Technique; Tritium | 1981 |
A combined radioimmunoassay for the measurement of unconjugated and sulfoconjugated pregnenolone, 17 hydroxypregnenolone, dehydroepiandrosterone, and estrone applied to fetal and maternal ovine plasma.
Topics: 17-alpha-Hydroxypregnenolone; Animals; Dehydroepiandrosterone; Estrone; Female; Fetal Blood; Pregnancy; Pregnenolone; Radioimmunoassay; Sheep | 1981 |
Serum steroid levels in children at birth and in early neonatal period.
Topics: 17-alpha-Hydroxypregnenolone; Adaptation, Physiological; Adrenal Cortex; Cortisone; Dehydroepiandrosterone; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Pregnenolone; Progesterone; Steroids | 1981 |
Functional and structural relationships in steroidogenesis in vitro by human corpora lutea during development and regression.
Topics: Acetates; Adult; Androgens; Corpus Luteum; Dehydroepiandrosterone; Estrogens; Female; Hormones; Humans; In Vitro Techniques; Luteolysis; Menstruation; Pregnenolone; Uterine Neoplasms | 1981 |
The control of steroidogenesis by human fetal adrenal cells in tissue culture. IV. The effect of exposure to placental steroids.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Cells, Cultured; Corticosterone; Cosyntropin; Dehydroepiandrosterone; Estrogens; Gonadal Steroid Hormones; Humans; Hydrocortisone; Pregnenolone; Progesterone | 1982 |
Side-chain cleavage of C21 steroids to C19 steroids by testicular microsomal cytochrome P-450: 17alpha-hydroxy C21 steroids as obligatory intermediates.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Microsomes; Pregnenolone; Progesterone; Swine; Testis | 1981 |
In vitro pregnenolone metabolism by mouse adrenal gland: II-Biosynthesis of androgens.
Topics: Adrenal Glands; Androgens; Animals; Breast Neoplasms; Castration; Dehydroepiandrosterone; Female; In Vitro Techniques; Male; Mice; NADP; Pregnenolone; Progesterone; Species Specificity; Testosterone | 1982 |
Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterisation of the expressed enzyme.
Topics: Adrenal Glands; Amino Acid Sequence; Androsterone; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cricetinae; Cricetulus; Dehydroepiandrosterone; DNA, Complementary; Gene Expression; Humans; Lung; Molecular Sequence Data; Pregnenolone; Recombinant Proteins; Substrate Specificity; Sulfates; Sulfotransferases; Transfection | 1995 |
Neuroactive steroids modulate in vivo the Mg2+/Ca(2+)-ATPase activity in rat cortical and cerebellar synaptosomal membranes.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calmodulin; Cell Membrane; Cerebellum; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Pregnenolone; Rats; Rats, Wistar; Reference Values; Synaptosomes | 1995 |
Avian neurosteroids. I. Pregnenolone biosynthesis in the quail brain.
Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Hypophysectomy; Immunoblotting; Male; Pregnenolone; Quail; Radioimmunoassay | 1995 |
Testicular steroidogenesis in the Cebus monkey throughout postnatal development.
Topics: Androstenedione; Animals; Cebus; Chorionic Gonadotropin; Dehydroepiandrosterone; Dihydrotestosterone; Male; Pregnenolone; Progesterone; Sexual Maturation; Steroids; Testis; Testosterone | 1995 |
Incorporation of bovine adrenal 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase into phospholipid vesicles.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Animals; Cattle; Centrifugation, Density Gradient; Cholic Acid; Cholic Acids; Chromatography, Gel; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Stability; Kinetics; Liposomes; Microsomes; Multienzyme Complexes; NAD; Phospholipids; Pregnenolone; Progesterone Reductase; Spectrophotometry; Steroid Isomerases | 1995 |
Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract.
Topics: Aldehyde-Lyases; Animals; Base Sequence; Colon; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Digestive System; DNA, Complementary; Duodenum; Esophagus; Female; Humans; Male; Molecular Sequence Data; Polymerase Chain Reaction; Pregnenolone; Rats; Rats, Sprague-Dawley; Rats, Wistar; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Stomach | 1995 |
Newly hatched chick ovarian cell subpopulations metabolize distinctively progestin and androgen precursors.
Topics: Androgens; Androstenedione; Animals; Cell Separation; Centrifugation, Density Gradient; Chickens; Dehydroepiandrosterone; Female; Hydroxysteroid Dehydrogenases; Ovary; Pregnenolone; Progestins; Steroid Hydroxylases; Testosterone | 1995 |
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella | 1995 |
The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androgens; Androstenedione; Cell Membrane; Cytochrome P-450 Enzyme System; Cytochromes b5; Dehydroepiandrosterone; Escherichia coli; Humans; Hydroxyprogesterones; Kinetics; Pregnenolone; Progesterone; Recombinant Proteins; Steroid 17-alpha-Hydroxylase | 1995 |
Neurosteroidogenesis in rat retinas.
Topics: Aminoglutethimide; Animals; Central Nervous System; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, High Pressure Liquid; Cyclic AMP; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Immunohistochemistry; Lovastatin; Male; Neurotransmitter Agents; Pregnenolone; Progesterone; Rats; Rats, Wistar; Retina; Steroids; Time Factors | 1994 |
Molecular basis of congenital adrenal hyperplasia in two siblings with classical nonsalt-losing 3 beta-hydroxysteroid dehydrogenase deficiency.
Topics: 3-Hydroxysteroid Dehydrogenases; Adolescent; Adrenal Hyperplasia, Congenital; Base Sequence; Dehydroepiandrosterone; Female; Genes; Humans; Kinetics; Male; Molecular Probes; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Pregnenolone; Recombinant Proteins | 1994 |
Key role for pregnenolone in combination therapy that promotes recovery after spinal cord injury.
Topics: Analysis of Variance; Animals; Aspirin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Blind Method; Drug Therapy, Combination; Female; Indomethacin; Lipopolysaccharides; Motor Activity; Pregnenolone; Rats; Rats, Sprague-Dawley; Salmonella enteritidis; Spinal Cord; Spinal Cord Injuries | 1994 |
Pregnenolone and dehydroepiandrosterone as precursors of native 7-hydroxylated metabolites which increase the immune response in mice.
Topics: Androstenediol; Animals; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxylation; Immunoglobulin G; Male; Mice; Mice, Inbred C57BL; Muramidase; Organ Specificity; Pregnenolone | 1994 |
Oxidation of steroidal 5-en-3 beta-ols with Jones reagent in ether.
Topics: Cholesterol; Chromates; Dehydroepiandrosterone; Deuterium; Diosgenin; Ether; Indicators and Reagents; Oxidation-Reduction; Pregnenolone; Sitosterols; Steroids; Sulfuric Acids | 1994 |
Site of macrophage inhibition of luteinizing hormone-stimulated testosterone production by purified leydig cells.
Topics: Androstenedione; Animals; Bucladesine; Cholera Toxin; Culture Media, Conditioned; Dehydroepiandrosterone; Hydroxycholesterols; Kinetics; Leydig Cells; Luteinizing Hormone; Macrophages; Male; Pregnenolone; Rats; Rats, Sprague-Dawley; Testis; Testosterone | 1994 |
Precursors of the neurosteroids.
Topics: Animals; Brain; Brain Chemistry; Dehydroepiandrosterone; Pregnenolone; Rats; Solvents | 1994 |
Inhibition of steroid sulphatase activity by steroidal methylthiophosphonates: potential therapeutic agents in breast cancer.
Topics: Antineoplastic Agents; Arylsulfatases; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Humans; Microsomes; Placenta; Pregnancy; Pregnenolone; Steryl-Sulfatase; Tumor Cells, Cultured | 1994 |
Neurosteroids do not regulate proopiomelanocortin-gene expression in pituitary cells.
Topics: Animals; Blotting, Northern; Brain Chemistry; Cells, Cultured; Corticosterone; Dehydroepiandrosterone; Gene Expression; Mice; Pituitary Gland; Pregnanolone; Pregnenolone; Pro-Opiomelanocortin; RNA, Messenger; Steroids | 1993 |
17-Hydroxylase and andien-beta synthetase activities in immature pig testis microsomal fraction: kinetic studies of the pregnenolone binding site and possible intermediates of the reactions.
Topics: Androstenols; Animals; Animals, Newborn; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; In Vitro Techniques; Kinetics; Male; Microsomes; Oxidoreductases; Pregnenolone; Steroid 17-alpha-Hydroxylase; Swine; Testis | 1993 |
Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alcohols; Androstenedione; Cyclic N-Oxides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hydroxyprogesterones; Ketones; Morpholines; Organometallic Compounds; Oxidants; Oxidation-Reduction; Pregnenediones; Pregnenolone; Quaternary Ammonium Compounds; Ruthenium; Steroids | 1993 |
Inhibition of estrone sulfatase and 17 beta-hydroxysteroid dehydrogenase by antiestrogens.
Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Binding, Competitive; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Polyunsaturated Alkamides; Pregnenolone; Rats; Rats, Sprague-Dawley; Sulfatases; Tamoxifen | 1993 |
Neurosteroids in rat sciatic nerves and Schwann cells.
Topics: Animals; Cells, Cultured; Corticosterone; Dehydroepiandrosterone; Hydroxycholesterols; In Vitro Techniques; Male; Pregnenolone; Rats; Rats, Sprague-Dawley; Schwann Cells; Sciatic Nerve; Steroids | 1993 |
Astrocytes and neurosteroids: metabolism of pregnenolone and dehydroepiandrosterone. Regulation by cell density.
Topics: Animals; Astrocytes; Carbon Monoxide; Cell Count; Cells, Cultured; Dehydroepiandrosterone; Female; Hydroxylation; Immunoenzyme Techniques; Kinetics; Oxidation-Reduction; Pregnancy; Pregnenolone; Rats; Rats, Sprague-Dawley | 1993 |
Enzyme characteristics of two distinct forms of mouse 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase complementary deoxyribonucleic acids expressed in COS-1 cells.
Topics: Androstane-3,17-diol; Animals; Blotting, Western; Catalysis; Cell Line; Dehydroepiandrosterone; DNA; Gene Expression; Immunoblotting; Kinetics; Mice; Multienzyme Complexes; NAD; Pregnenolone; Progesterone Reductase; Recombinant Proteins; Ribonucleases; Steroid Isomerases; Substrate Specificity; Transfection | 1993 |
Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors.
Topics: Animals; Anisoles; Dehydroepiandrosterone; Drug Synergism; Female; Guanidines; Haloperidol; Hippocampus; Iontophoresis; Ligands; Male; N-Methylaspartate; Pertussis Toxin; Pregnenolone; Progesterone; Propylamines; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Spiperone; Virulence Factors, Bordetella | 1996 |
Formation of pregnenolone- and dehydroepiandrosterone-fatty acid esters by lecithin-cholesterol acyltransferase in human plasma high density lipoproteins.
Topics: Adult; Animals; Apolipoprotein A-I; Cholesterol; Dehydroepiandrosterone; Esterification; Esters; Fatty Acids; Female; Guinea Pigs; Humans; Lipoproteins, HDL; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Pregnenolone; Rats; Species Specificity | 1996 |
3 beta-hydroxysteroid dehydrogenase/isomerase and aromatase activity in primary cultures of developing zebra finch telencephalon: dehydroepiandrosterone as substrate for synthesis of androstenedione and estrogens.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase; Birds; Cells, Cultured; Dehydroepiandrosterone; Estrogen Antagonists; Estrogens; Fadrozole; Female; In Vitro Techniques; Male; Pregnenolone; Progesterone; Telencephalon; Time Factors | 1996 |
Steroid metabolism in theca externa cells from preovulatory follicles of domestic hen (Gallus domesticus).
Topics: Androstenedione; Animals; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Steroids; Testosterone; Theca Cells | 1996 |
Neurosteroids block the memory-impairing effects of ethanol in mice.
Topics: Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Pregnenolone; Rats; Steroids | 1996 |
Neurosteroids in the mouse brain: behavioral and pharmacological effects of a 3 beta-hydroxysteroid dehydrogenase inhibitor.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Mice; Pregnanolone; Pregnenolone; Progesterone; Sexual Behavior, Animal | 1996 |
Studies of the enzyme complex responsible for pregnenolone and dehydroepiandrosterone 7 alpha-hydroxylation in mouse tissues.
Topics: Age Factors; Animals; Brain; Dehydroepiandrosterone; Enzymes; Hydrogen-Ion Concentration; Hydroxylation; Ions; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Microsomes; Microsomes, Liver; Myocardium; Pregnenolone; Spleen; Subcellular Fractions; Thymus Gland; Tissue Distribution | 1996 |
Detergent solubilization of 3 beta-hydroxysteroid dehydrogenase from dog pancreas.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cholic Acids; Dehydroepiandrosterone; Detergents; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Mitochondria; Pancreas; Pregnenolone; Solubility; Substrate Specificity | 1996 |
Potentiation by dehydroepiandrosterone of the neuronal response to N-methyl-D-aspartate in the CA3 region of the rat dorsal hippocampus: an effect mediated via sigma receptors.
Topics: Acetylcholine; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Female; Hippocampus; Male; N-Methylaspartate; Ovariectomy; Pregnenolone; Progesterone; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stimulation, Chemical; Testosterone | 1996 |
Transfer of dehydroepiandrosterone- and pregnenolone-fatty acid esters between human lipoproteins.
Topics: Adult; Biological Transport; Blotting, Western; Carrier Proteins; Cholesterol Ester Transfer Proteins; Dehydroepiandrosterone; Esters; Fatty Acids; Glycoproteins; Humans; Kinetics; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Pregnenolone | 1997 |
Occurrence of steroidogenic enzymes in the bovine mammary gland at different functional stages.
Topics: Acyltransferases; Animals; Aromatase; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Female; Gene Expression Regulation, Enzymologic; Hydroxysteroid Dehydrogenases; Lactation; Mammary Glands, Animal; Multienzyme Complexes; Organ Specificity; Pregnancy; Pregnenolone; Progesterone; Progesterone Reductase; RNA, Messenger; Steroid Isomerases; Steroids | 1996 |
Pregnenolone-7 beta-hydroxylating activities of yeast-expressed mouse cytochrome P450-1A1 and mouse-tissue microsomes.
Topics: Animals; Brain; Cytochrome P-450 CYP1A1; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Kinetics; Mice; Mice, Inbred C57BL; Microsomes; Microsomes, Liver; Pregnenolone; Saccharomyces cerevisiae; Substrate Specificity | 1996 |
The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.
Topics: Animals; Cattle; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Escherichia coli; Genetic Vectors; NADPH-Ferrihemoprotein Reductase; Pregnenolone; Progesterone; Rats; Recombinant Proteins; Solubility; Steroid 17-alpha-Hydroxylase | 1997 |
Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase.
Topics: Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Line, Transformed; Cholestenones; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dexamethasone; Humans; Hydrocortisone; Hydroxycholesterols; Hydroxylation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metyrapone; Pregnenolone; Steroid Hydroxylases; Tumor Cells, Cultured | 1997 |
Isolation of a new mouse 3beta-hydroxysteroid dehydrogenase isoform, 3beta-HSD VI, expressed during early pregnancy.
Topics: Adrenal Glands; Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Blotting, Western; COS Cells; Dehydroepiandrosterone; Female; Gonads; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Polymerase Chain Reaction; Pregnancy; Pregnenolone; Progesterone Reductase; Uterus | 1997 |
Glucocorticoid- and mineralocorticoid receptors in microglial cells: the two receptors mediate differential effects of corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Androstanols; Animals; Animals, Newborn; Cells, Cultured; Cholesterol; Corticosterone; Culture Media; Culture Media, Serum-Free; Dehydroepiandrosterone; Dexamethasone; Estradiol; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrocortisone; Microglia; Mifepristone; Pregnenolone; Proliferating Cell Nuclear Antigen; Prosencephalon; Rats; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Testosterone | 1997 |
Pregnenolone-7beta-hydroxylating activity of human cytochrome P450-1A1.
Topics: Chromatography, Gas; Crystallization; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Humans; Hydroxylation; Kinetics; Liver; Mass Spectrometry; Microsomes; Pregnenolone; Recombinant Proteins; Yeasts | 1997 |
Subcellular localization of 3 beta hydroxysteroid dehydrogenase isomerase in testis of Bufo arenarum H.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Bufo arenarum; Dehydroepiandrosterone; Kinetics; Male; Microsomes; Mitochondria; Multienzyme Complexes; Pregnenolone; Progesterone; Progesterone Reductase; Proteins; Reproduction; Steroid Isomerases; Subcellular Fractions; Testis | 1997 |
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Aged; Aged, 80 and over; Aging; Androgens; Androstenediol; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Pregnenolone; Protein Precursors; Reference Values | 1997 |
Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells.
Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Electrophysiology; GABA Modulators; gamma-Aminobutyric Acid; Neurotransmitter Agents; Patch-Clamp Techniques; Pentobarbital; Pituitary Gland; Pregnenolone; Rana ridibunda; Receptors, GABA-A; Steroids | 1997 |
Steroid sulphotransferase and 17beta-hydroxysteroid dehydrogenase activities in Ishikawa human endometrial adenocarcinoma cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Adenocarcinoma; Dehydroepiandrosterone; Endometrial Neoplasms; Estrogens; Estrone; Female; Humans; Pregnenolone; Sulfotransferases; Testosterone; Tumor Cells, Cultured | 1997 |
Chronic neurosteroid treatment prevents the development of morphine tolerance and attenuates abstinence behavior in mice.
Topics: Analgesics, Opioid; Animals; Dehydroepiandrosterone; Drug Tolerance; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pregnanolone; Pregnenolone; Reaction Time; Steroids; Substance Withdrawal Syndrome | 1997 |
A colorimetric assay method for 3beta-hydroxy-delta5-steroid dehydrogenase.
Topics: Adrenal Glands; Animals; Colorimetry; Dehydroepiandrosterone; Enzyme Stability; Female; Gerbillinae; Hydrogen-Ion Concentration; Kinetics; Male; Mice; NAD; Pregnenolone; Progesterone Reductase; Rats; Rats, Wistar; Sensitivity and Specificity; Spectrophotometry; Testis; Tetrazolium Salts | 1997 |
Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metabolites of pregnenolone in mouse brain microsomes.
Topics: Androsterone; Animals; Antipyrine; Brain; Chromatography, Thin Layer; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Hydroxylation; Male; Metyrapone; Mice; Mice, Inbred C57BL; Microsomes; Pregnenolone | 1997 |
Two steroidogenic pathways present in the chicken ovary: theca layer prefers delta 5 pathway and granulosa layer prefers delta 4 pathway.
Topics: Animals; Chickens; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Ovarian Follicle; Pregnenolone; Steroids; Testosterone; Theca Cells; Tritium | 1998 |
Sigma1 (sigma 1) receptor agonists and neurosteroids attenuate B25-35-amyloid peptide-induced amnesia in mice through a common mechanism.
Topics: Amnesia; Amyloid beta-Peptides; Analgesics, Opioid; Animals; Antipsychotic Agents; Avoidance Learning; Dehydroepiandrosterone; Haloperidol; Injections, Intraventricular; Male; Mice; Morpholines; Pentazocine; Peptide Fragments; Piperazines; Pregnenolone; Progesterone; Receptors, sigma | 1998 |
Biochemical characterization of the 7alpha-hydroxylase activities towards 27-hydroxycholesterol and dehydroepiandrosterone in pig liver microsomes.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxycholesterols; Microsomes, Liver; Pregnenolone; Substrate Specificity; Swine | 1998 |
Detection of P450c17-independent pathways for dehydroepiandrosterone (DHEA) biosynthesis in brain glial tumor cells.
Topics: Aminoglutethimide; Animals; Brain Neoplasms; Cholesterol Side-Chain Cleavage Enzyme; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Ferrous Compounds; Glioma; Leydig Cells; Male; Microsomes; Models, Chemical; Neuroglia; Pregnenolone; Rats; Steroid 17-alpha-Hydroxylase; Tetrahydronaphthalenes; Tumor Cells, Cultured | 1998 |
Differences in natural steroid hormone patterns of beef from bulls and steers.
Topics: Animals; Cattle; Dehydroepiandrosterone; Epitestosterone; Gas Chromatography-Mass Spectrometry; Hormones; Hydrocortisone; Male; Meat; Pregnenolone; Quality Control; Steroids; Testosterone | 1998 |
Contribution of human hepatic cytochrome P450 isoforms to regioselective hydroxylation of steroid hormones.
Topics: Aryl Hydrocarbon Hydroxylases; Cloning, Molecular; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estrone; Humans; Hydroxylation; Isoenzymes; Kinetics; Liver; Microsomes; Microsomes, Liver; Pregnenolone; Progesterone; Recombinant Proteins; Saccharomyces cerevisiae; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Xenobiotics | 1998 |
Androstenedione and progesterone production in vitro by the inner or the outer theca cells in preovulatory follicles of gonadotropin stimulated calves.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Cattle; Cells, Cultured; Chorionic Gonadotropin; Dehydroepiandrosterone; Female; Hydroxycholesterols; Ovarian Follicle; Ovulation; Pregnenolone; Progesterone; Theca Cells; Time Factors | 1998 |
Steroid metabolism in granulosa and theca interna cells from preovulatory follicles of domestic hen (Gallus domesticus).
Topics: Androstenedione; Animals; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Granulosa Cells; Ovarian Follicle; Pregnenolone; Progesterone; Radionuclide Imaging; Steroids; Testosterone; Theca Cells | 1998 |
SXR, a novel steroid and xenobiotic-sensing nuclear receptor.
Topics: Amino Acid Sequence; Base Sequence; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; DNA-Binding Proteins; Enzyme Induction; Humans; Molecular Sequence Data; Pregnane X Receptor; Pregnenolone; Receptors, Steroid; Xenobiotics | 1998 |
Pregnenolone and progesterone metabolism by the testes of Bufo arenarum.
Topics: 5-alpha-Dihydroprogesterone; Androgens; Androstenediol; Androstenedione; Animals; Bufo arenarum; Carbon Radioisotopes; Dehydroepiandrosterone; In Vitro Techniques; Male; Pregnanediones; Pregnenolone; Progesterone; Testis; Testosterone; Tritium | 1998 |
Hepatic and extrahepatic dehydrogenation/isomerization of 5-cholestene-3 beta,7 alpha-diol: localization of 3 beta-hydroxy-delta 5-C27-steroid dehydrogenase in pig tissues and subcellular fractions.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Antibodies, Monoclonal; Bile Acids and Salts; Bile Ducts; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Hydroxycholesterols; Immunohistochemistry; Liver; Male; Microsomes; Microsomes, Liver; Pregnenolone; Subcellular Fractions; Swine; Tissue Distribution | 1999 |
Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury.
Topics: Animals; Astrocytes; Brain Injuries; Cerebral Cortex; Dehydroepiandrosterone; Dentate Gyrus; Estradiol; Glial Fibrillary Acidic Protein; Gliosis; Gonadal Steroid Hormones; Hippocampus; Male; Orchiectomy; Pregnenolone; Progesterone; Rats; Testosterone | 1999 |
Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Androgens; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Dehydroepiandrosterone; Female; Gene Expression Regulation; Humans; Phenotype; Phosphoproteins; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Reference Values; Steroid 17-alpha-Hydroxylase; Theca Cells | 1999 |
Transformation of 3-hydroxy-steroids by Fusarium moniliforme 7alpha-hydroxylase.
Topics: Androsterone; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Estrone; Fusarium; Hydroxysteroids; Microsomes; Pregnenolone; Steroid Hydroxylases | 1999 |
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.
Topics: 5-alpha-Dihydroprogesterone; Adrenal Cortex; Animals; Brain; Brain Chemistry; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Demyelinating Diseases; Diazepam Binding Inhibitor; Immunohistochemistry; Leydig Cells; Male; Mice; Mice, Inbred Strains; Mice, Jimpy; Mice, Neurologic Mutants; Neuropeptides; Organ Specificity; Peptide Fragments; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Up-Regulation | 2000 |
Biotransformation XLVII: transformations of 5-ene steroids in Fusarium culmorum culture.
Topics: Androstenedione; Androstenols; Biotransformation; Chromatography, Gas; Dehydroepiandrosterone; Fusarium; Hydroxylation; Magnetic Resonance Spectroscopy; Pregnenolone; Steroids | 1999 |
Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and beta-amyloid peptide.
Topics: 3-Hydroxysteroid Dehydrogenases; Amyloid beta-Peptides; Astrocytes; Brain; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Ferrous Compounds; Humans; Intracellular Membranes; Neurons; Oligodendroglia; Oxidative Stress; Pregnenolone; Reactive Oxygen Species; Receptors, GABA-A; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Steroids; Tumor Cells, Cultured | 2000 |
Studies on neurosteroids X. Determination of pregnenolone and dehydroepiandrosterone in rat brains using gas chromatography-mass spectrometry-mass spectrometry.
Topics: Animals; Brain Chemistry; Calibration; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Pregnenolone; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results | 2000 |
Correlation between PAP-dependent steroid binding activity and substrate specificity of mouse and human estrogen sulfotransferases.
Topics: Animals; Base Sequence; CHO Cells; Cricetinae; Dehydroepiandrosterone; DNA Primers; Escherichia coli; Estradiol; Guinea Pigs; Humans; In Vitro Techniques; Mice; Mutagenesis, Site-Directed; Phosphoadenosine Phosphosulfate; Pregnenolone; Recombinant Proteins; Steroids; Substrate Specificity; Sulfotransferases | 1999 |
Differential effect of dehydroepiandrosterone and its steroid precursor pregnenolone against the behavioural deficits in CO-exposed mice.
Topics: Animals; Anisoles; Antipsychotic Agents; Behavior, Animal; Carbon Monoxide Poisoning; Dehydroepiandrosterone; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Memory, Short-Term; Mice; Nerve Degeneration; Pregnenolone; Propylamines | 2000 |
Analysis of oxosteroids by nano-electrospray mass spectrometry of their oximes.
Topics: Dehydroepiandrosterone; Ketosteroids; Mass Spectrometry; Oximes; Pregnenolone; Progesterone; Solvents | 2000 |
Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Pregnenolone; Thyroid Hormones | 2000 |
Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
Topics: 17-alpha-Hydroxypregnenolone; Cell Line; Cytochromes b5; Dehydroepiandrosterone; Humans; Kidney; NADPH-Ferrihemoprotein Reductase; Pregnenolone; Recombinant Fusion Proteins; Steroid 17-alpha-Hydroxylase; Transfection | 2000 |
Dexamethasone-induced apoptosis of mouse thymocytes: prevention by native 7alpha-hydroxysteroids.
Topics: Androsterone; Animals; Apoptosis; Carbon Radioisotopes; Cells, Cultured; Dehydroepiandrosterone; Dexamethasone; Flow Cytometry; Hydroxysteroids; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Organ Size; Pregnenolone; Thymus Gland | 2000 |
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Topics: Animals; Anxiety; Brain; Cerebral Cortex; Conflict, Psychological; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Electroshock; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Oocytes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Social Isolation; Steroids; Synaptosomes; Time Factors; Xenopus laevis | 2000 |
Adrenocortical hyperresponsivity to adrenocorticotropic hormone: a mechanism favoring the normal production of cortisol in 21-hydroxylase-deficient nonclassic adrenal hyperplasia.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Cortodoxone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hydrocortisone; Pregnenolone; Progesterone; Prospective Studies; Steroid 21-Hydroxylase | 2000 |
The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; 3-Hydroxysteroid Dehydrogenases; Animals; Carbolines; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Diazepam Binding Inhibitor; Dihydrotestosterone; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Hydroxysteroids; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Ligands; Male; Neuroglia; Neurons; Neuropeptides; Peptide Fragments; Pregnenolone; Progesterone; Rana ridibunda; Receptors, GABA-A | 2001 |
Enhanced dehydroepiandrosterone synthesis by amnion compared to chorion: a comparative study using the reverse-isotope dilution technique.
Topics: Amnion; Chorion; Crystallization; Dehydroepiandrosterone; Female; Humans; Placenta; Pregnancy; Pregnenolone; Radioisotope Dilution Technique; Tissue Extracts; Tritium | 2001 |
Pathways of dehydroepiandrosterone formation in rat brain glia.
Topics: Animals; Brain; Cell Differentiation; Cells, Cultured; Cerebral Cortex; Dehydroepiandrosterone; Ferrous Compounds; Immunohistochemistry; Microsomes; Neuroglia; Pregnenolone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 2000 |
Follicle-stimulating hormone regulates steroidogenic enzymes in cultured cells of the chick embryo ovary.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase; Cells, Cultured; Chick Embryo; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dehydroepiandrosterone; Estrone; Female; Follicle Stimulating Hormone; Gene Expression Regulation, Enzymologic; Humans; Ovary; Pregnenolone; Progesterone; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Testosterone; Time Factors; Tritium | 2001 |
Leukemia inhibitory factor antagonizes gonadotropin induced-testosterone synthesis in cultured porcine leydig cells: sites of action.
Topics: Androstenedione; Animals; Cells, Cultured; Cholera Toxin; Cholesterol; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Dinoprostone; Gene Expression; Growth Inhibitors; Hydroxycholesterols; Interleukin-6; Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor alpha Subunit; Leydig Cells; Luteinizing Hormone; Lymphokines; Male; Mitochondria; Phosphoproteins; Pregnenolone; Receptors, Cytokine; Receptors, OSM-LIF; RNA, Messenger; Swine; Testis; Testosterone | 2001 |
Neuroactive steroid levels in patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Dehydroepiandrosterone; Female; gamma-Aminobutyric Acid; Humans; Male; Pregnanolone; Pregnenolone; Receptors, GABA-A | 2001 |
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Androstenediol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Pregnenolone; Sex Characteristics; Sex Hormone-Binding Globulin; Thyroxine | 2001 |
Ontogeny of steroid metabolizing enzymes in rat oligodendrocytes.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Male; Oligodendroglia; Pregnenolone; Progesterone; Radioimmunoassay; Rats; Rats, Wistar; Sex Factors; Steroids; Testosterone | 2001 |
Pregnenolone sulfate modulates angiotensin II-induced inositol 1,4,5-trisphosphate changes in the anterior pituitary of female rat.
Topics: Adjuvants, Immunologic; Angiotensin II; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Estradiol; Female; Inositol 1,4,5-Trisphosphate; Ovary; Pituitary Gland; Pregnenolone; Progesterone; Rats | 2001 |
Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androgens; Animals; Bufonidae; Cholestenone 5 alpha-Reductase; Cyanoketone; Dehydroepiandrosterone; Enzyme Inhibitors; Finasteride; Male; Oxidoreductases; Pregnenolone; Spironolactone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone | 2001 |
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine | 2001 |
Hormonal steroidogenesis in liver and small intestine of the green frog, Rana esculenta L.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Androstenediol; Androstenedione; Animals; Autoradiography; Cholesterol; Chromatography, Thin Layer; Dehydroepiandrosterone; Female; Intestine, Small; Liver; Male; Mitochondria, Liver; Pregnenolone; Progesterone; Rana esculenta; Sex Factors | 2001 |
Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding Sites; Blotting, Western; Brain; Cerebral Cortex; Dehydroepiandrosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory; Mice; Morpholines; Oligonucleotides, Antisense; Phenazocine; Pregnenolone; Receptors, sigma; Sigma-1 Receptor | 2001 |
Expression of 3 beta-hydroxysteroid dehydrogenase in early bovine embryo development.
Topics: 3-Hydroxysteroid Dehydrogenases; Amanitins; Animals; Blastocyst; Cattle; Cells, Cultured; Dehydroepiandrosterone; Embryonic and Fetal Development; Female; Fertilization in Vitro; Nucleic Acid Synthesis Inhibitors; Oocytes; Pregnancy; Pregnenolone; Progesterone; RNA, Messenger | 2002 |
A hydroxysteroid sulfotransferase, st2b2, is a skin cholesterol sulfotransferase in mice.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Cholesterol; Dehydroepiandrosterone; DNA Primers; Female; Liver; Male; Mice; Pregnenolone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Sulfotransferases; Sulfur; Tetradecanoylphorbol Acetate | 2002 |
Effect of clofibrate administration on the esterification and deesterification of steroid hormones by liver and extrahepatic tissues in rats.
Topics: Animals; Anticholesteremic Agents; Clofibrate; Corticosterone; Dehydroepiandrosterone; Esterases; Esterification; Estradiol; Female; Liver; Microsomes, Liver; Pregnenolone; Rats; Rats, Sprague-Dawley; Steroids; Testosterone; Tissue Distribution | 2002 |
Evidence for the biosynthesis of DHEA from cholesterol by first-trimester human placental tissue: source of androgens.
Topics: Adult; Androgens; Caproates; Cholesterol; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Pregnancy Trimester, First; Pregnenolone | 2002 |
Accumulation of 4- and 5-ene steroid sulfates in human breast cyst fluids.
Topics: Adult; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Middle Aged; Pregnenolone | 2002 |
Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia.
Topics: Adult; Arousal; Dehydroepiandrosterone; Humans; Male; Middle Aged; Phobic Disorders; Pilot Projects; Pregnanolone; Pregnenolone; Reference Values | 2002 |
Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone-induced suppression.
Topics: Age Factors; Androstenediol; Animals; Cell Death; Cell Differentiation; Cell Division; Cell Survival; Corticosterone; Dehydroepiandrosterone; Dentate Gyrus; Depressive Disorder, Major; Drug Administration Schedule; Drug Interactions; Immunohistochemistry; Male; Neurons; Neuroprotective Agents; Pregnenolone; Rats; Rats, Inbred Strains; Stem Cells | 2002 |
Detection of oestrogenic activity of steroids present during mammalian gestation using oestrogen receptor alpha- and oestrogen receptor beta-specific in vitro assays.
Topics: Androgens; Animals; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Gestational Age; Hormones; Humans; Kidney; Mice; Pregnenolone; Protein Binding; Protein Precursors; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation; Transfection | 2002 |
Histological and metabolism analysis of P450 expression in the brain.
Topics: Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Estradiol; Excitatory Amino Acid Agonists; Female; Hippocampus; Immunohistochemistry; Male; N-Methylaspartate; Ovary; Pregnenolone; Radioimmunoassay; Rats; Rats, Wistar; Testis | 2002 |
Serum concentrations of delta 5-3 beta-hydroxysteroids in type 2 diabetes mellitus.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androstenediol; Dehydroepiandrosterone; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Pregnenolone; Statistics, Nonparametric | 2002 |
Xenopus laevis ovarian CYP17 is a highly potent enzyme expressed exclusively in oocytes. Evidence that oocytes play a critical role in Xenopus ovarian androgen production.
Topics: Androgens; Animals; Cell Line; Cell Membrane; Chorionic Gonadotropin, beta Subunit, Human; Dehydroepiandrosterone; Female; Humans; Kinetics; Models, Biological; Oocytes; Ovary; Phylogeny; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Testosterone; Time Factors; Transfection; Xenopus laevis | 2003 |
Serum levels of pregnenolone and 17-hydroxypregnenolone in patients with rheumatoid arthritis and systemic lupus erythematosus: relation to other adrenal hormones.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adult; Aged; Androstenedione; Arthritis, Rheumatoid; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Lupus Erythematosus, Systemic; Male; Middle Aged; Pregnenolone; Progesterone | 2003 |
Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor. Role of recombinant cytochrome b5 and P450 reductase.
Topics: Androstenols; Animals; Cell Line; Cytochromes b5; Dehydroepiandrosterone; Humans; Molecular Structure; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Pregnenolone; Steroid 17-alpha-Hydroxylase; Swine | 2003 |
Sigma 1 receptor-related neuroactive steroids modulate cocaine-induced reward.
Topics: Animals; Behavior, Animal; Cinnamates; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cyclopropanes; Dehydroepiandrosterone; Disease Susceptibility; Drug Antagonism; Drug Synergism; Enzyme Inhibitors; Finasteride; Male; Mice; Mice, Inbred C57BL; Motor Activity; Pregnenolone; Progesterone; Receptors, sigma; Reward; Sigma-1 Receptor; Steroids | 2003 |
The human kidney is a progesterone-metabolizing and androgen-producing organ.
Topics: Androgens; Dehydroepiandrosterone; Humans; Kidney; Pregnenolone; Progesterone; Subcellular Fractions | 2003 |
Neurosteroid secretion in panic disorder.
Topics: Adult; Analysis of Variance; Case-Control Studies; Dehydroepiandrosterone; Desoxycorticosterone; Female; Humans; Panic Disorder; Pregnenolone; Progesterone | 2003 |
DHEA, PREG and their sulphate derivatives on plasma and brain after CRH and ACTH administration.
Topics: Adrenocorticotropic Hormone; Animals; Blood; Brain; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Male; Pregnenolone; Rats; Rats, Wistar | 2003 |
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Catalysis; Dehydroepiandrosterone; Female; Humans; Kinetics; Leydig Cells; Male; Microsomes; Multienzyme Complexes; Pregnancy; Pregnanolone; Pregnenolone; Progesterone; Progesterone Reductase; Steroid 17-alpha-Hydroxylase; Steroid Isomerases; Steroids; Testis | 2003 |
Neuroprotection by the steroids pregnenolone and dehydroepiandrosterone is mediated by the enzyme aromatase.
Topics: Animals; Aromatase; Aromatase Inhibitors; Dehydroepiandrosterone; Dentate Gyrus; Male; Neuroprotective Agents; Pregnenolone; Rats; Rats, Wistar; Steroids | 2003 |
Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
Topics: Adenosine Diphosphate; Aspartic Acid; Binding Sites; Cholesterol; Crystallization; Crystallography, X-Ray; Dehydroepiandrosterone; Escherichia coli; Gene Expression; Humans; Hydrogen Bonding; Isoenzymes; Lysine; Models, Molecular; Molecular Structure; Pregnenolone; Protein Structure, Secondary; Recombinant Fusion Proteins; Substrate Specificity; Sulfotransferases; Transfection | 2003 |
The conversion in vivo of 17-alpha-hydroxypregnenolone to dehydroisoandrosterone and other 17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Androgens; Biological Assay; Dehydroepiandrosterone; Humans; Lipid Metabolism; Pregnenolone | 1960 |
Conversion of pregnenolone to dehydroepiandrosterone.
Topics: Androgens; Dehydroepiandrosterone; Female; Humans; Pregnenolone; Progesterone | 1960 |
Steroidogenesis in the human fetal testis: the conversion of pregnenolone-7alpha-H3 to dehydroepiandrosterone, testosterone and 4-androstene-3,17-dione.
Topics: Androgens; Androstenedione; Androstenes; Dehydroepiandrosterone; Fetus; Humans; Lipid Metabolism; Male; Pregnenolone; Testis; Testosterone | 1961 |
Biosynthesis of dehydroepiandrosterone in a patient with a virilizing adenoma.
Topics: Adenoma; Carbon Isotopes; Cholesterol; Dehydroepiandrosterone; Humans; Pregnenolone | 1962 |
Effect of dehydroisoandrosterone on the in vivo conversion of 17Alpha-hydroxypregnenolone to urinary 11-desoxy-17-ketosteroids.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Dehydroepiandrosterone; Humans; Pregnenolone | 1963 |
[The clinical and pathological significance of the determination of steroid glucuronates excreted in the urine].
Topics: Dehydroepiandrosterone; Glucuronates; Humans; Pregnenolone; Progesterone; Steroids; Testosterone | 1962 |
[SPECIFICITY OF HELIX POMATIA SULFATASES. STUDY OF THE KINETICS OF HYDROLYSIS OF SULFATED ESTERS].
Topics: 17-Ketosteroids; Borates; Catechols; Chlorides; Cortisone; Dehydroepiandrosterone; Enzyme Inhibitors; Esters; Estrone; Hydrolysis; Kinetics; Nitrophenols; Phenolphthaleins; Phosphates; Pregnenolone; Research; Snails; Steroids; Sulfatases; Sulfates; Testosterone | 1963 |
STEROIDS IN THE SEMEN OF DOGFISH (SQUALUS ACANTHIAS).
Topics: Aldosterone; Androgens; Androsterone; Animals; Dehydroepiandrosterone; Desoxycorticosterone; Dogfish; Fishes; Pregnenolone; Progesterone; Research; Semen; Squalus acanthias; Steroids | 1963 |
THE DETERMINATION OF STEROIDS IN CYST FLUID FROM HUMAN POLYCYSTIC OVARIES.
Topics: Androgens; Chromatography; Cyst Fluid; Cysts; Dehydroepiandrosterone; Endometriosis; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyprogesterones; Leiomyoma; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Salpingitis; Testosterone | 1963 |
METABOLISM IN VIVO OF (7ALPHA-3H) PREGNENOLONE BY THE DOG OVARY.
Topics: Androsterone; Chorionic Gonadotropin; Chromatography; Dehydroepiandrosterone; Dogs; Estradiol; Female; Gonadotropins; Humans; Hydroxyprogesterones; Metabolism; Ovary; Pregnenolone; Progesterone; Research; Testosterone; Tritium | 1963 |
IN VITRO BIOSYNTHESIS OF CORTICOSTEROID SULFATES BY ADRENAL TUMORAL TISSUE.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Carbon Isotopes; Chromatography; Corticosterone; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Hydrocortisone; In Vitro Techniques; Metabolism; Pathology; Pregnenolone; Sulfates; Urine | 1963 |
ENZYMIC SYNTHESIS OF STEROID SULPHATES. I. SULPHATION OF STEROIDS BY HUMAN ADRENAL EXTRACTS.
Topics: 17-Ketosteroids; Adenine Nucleotides; Adrenal Glands; Aldosterone; Androsterone; Autoradiography; Chromatography; Cortisone; Dehydroepiandrosterone; Desoxycorticosterone; Estrone; Humans; Hydrocortisone; Metabolism; Pregnenolone; Research; Steroids; Sulfates; Sulfur Isotopes; Testosterone; Tissue Extracts; Transferases | 1964 |
STUDIES ON ESTER SULPHATES. 21. ON SULPHATE CONJUGATION IN FOETAL HUMAN TISSUE EXTRACTS.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Androsterone; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Estriol; Etiocholanolone; Fetus; Humans; Kidney; Liver; Lung; Metabolism; Phenols; Pregnenolone; Sodium; Spleen; Sulfates; Testosterone; Tissue Extracts | 1964 |
EVIDENCE THAT STEROID SULFATES SERVE AS BIOSYNTHETIC INTERMEDIATES. II. IN VITRO CONVERSION OF PREGNENOLONE-3H SULFATE-35S TO 17ALPHA-HYDROXYPREGNENOLONE-3H SULFATE-35S.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Humans; In Vitro Techniques; Infrared Rays; Metabolism; Pregnanediol; Pregnenolone; Sulfates; Sulfur Isotopes; Tritium; Urine | 1964 |
EFFECTS OF SUBSTRATES AND COFACTORS ON STEROID SYNTHESIS IN HYPERPLASTIC ADRENALS.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Hyperplasia, Congenital; Carbon Isotopes; Chromatography; Corticosterone; Cushing Syndrome; Dehydroepiandrosterone; Estrone; Hexosephosphates; Hydrocortisone; Metabolism; NAD; NADP; Pregnenolone; Progesterone; Research; Tritium | 1964 |
METABOLISM IN VIVO OF (7-ALPHA-3H) PREGNENOLONE BY THE OVARY OF DOGS TREATED WITH FOLLICLE STIMULATING HORMONE.
Topics: Androgens; Animals; Blood; Chromatography; Dehydroepiandrosterone; Dogs; Estradiol; Female; Follicle Stimulating Hormone; Histology; Humans; Hydroxyprogesterones; Luteinizing Hormone; Metabolism; Ovary; Pharmacology; Pregnenolone; Progesterone; Research; Testosterone; Tritium | 1964 |
[PHYSIOLOGY OF OVARIAN STEROID GENESIS].
Topics: Cholesterol; Dehydroepiandrosterone; Estradiol; Estrogens; Estrone; Female; Humans; Hydroxyprogesterones; Ovary; Physiology; Pregnenolone; Progesterone; Testosterone | 1964 |
THE ACTION OF FOLLICLE STIMULATING HORMONE AND OF HUMAN CHORIONIC GONADOTROPHIN UPON STEROID SYNTHESIS BY RABBIT OVARIAN TISSUES IN VITRO.
Topics: Acetates; Androgens; Animals; Carbon Isotopes; Cholesterol; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; In Vitro Techniques; Metabolism; Ovary; Pharmacology; Pregnenolone; Progesterone; Rabbits; Research; Sodium; Testosterone; Tissue Culture Techniques | 1964 |
THE IN VITRO PRODUCTION OF ANDROGENS BY FOLLICULAR TISSUE OF RABBITS.
Topics: Androgens; Animals; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; In Vitro Techniques; Ovarian Follicle; Pregnenolone; Progesterone; Rabbits; Research; Testosterone; Tissue Culture Techniques | 1964 |
EFFECT OF ANDROGENS ON STEROID C-21 HYDROXYLATION.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Androgens; Chemical Phenomena; Chemistry; Dehydroepiandrosterone; Hydrocortisone; Hydroxylation; Hydroxyprogesterones; Metabolism; Metyrapone; Microsomes; Mixed Function Oxygenases; Naphthalenes; Pharmacology; Pregnenolone; Progesterone; Pyridines; Research; Steroids; Testosterone | 1964 |
THE CONVERSION OF PREGNENOLONE TO PROGESTERONE BY SMALL PARTICLES FROM RAT ADRENAL.
Topics: Adrenal Glands; Androgens; Chemical Phenomena; Chemistry; Cholesterol; Dehydroepiandrosterone; Enzyme Inhibitors; Metabolism; NAD; NADP; Physiology; Pregnenolone; Progesterone; Progestins; Rats; Research | 1964 |
STEROID SYNTHESIS IN ABNORMAL OVARIES. 1. ARRHENOBLASTOMA.
Topics: 17-Ketosteroids; Androgens; Biochemical Phenomena; Biochemistry; Blood Chemical Analysis; Castration; Chromatography; Dehydroepiandrosterone; Female; Humans; Hysterectomy; Male; Metabolism; Ovarian Neoplasms; Ovary; Physiology; Pregnenolone; Progesterone; Sertoli-Leydig Cell Tumor; Testosterone | 1964 |
STEROID SYNTHESIS IN ABNORMAL OVARIES. II. GRANULOSA CELL TUMOR.
Topics: Androgens; Chromatography; Corpus Luteum Hormones; Dehydroepiandrosterone; Endometrial Hyperplasia; Estradiol; Estrone; Female; Granulosa Cell Tumor; Humans; Hydroxyprogesterones; Ovarian Neoplasms; Physiology; Pregnenolone; Progesterone; Testosterone | 1964 |
A HISTOCHEMICAL STUDY OF SUBSTRATE SPECIFICITY FOR THE STEROID 3 BETA-OL DEHYDROGENASE AND ISOMERASE SYSTEMS IN HUMAN OVARY AND TESTIS.
Topics: Androgens; Dehydroepiandrosterone; Estradiol; Female; Histocytochemistry; Humans; Isomerases; Male; Ovary; Oxidoreductases; Pregnenolone; Progesterone; Rats; Substrate Specificity; Testis | 1964 |
STEROL METABOLISM IN LARVAE OF THE CONFUSED FLOUR BEETLE, TRIBOLIUM CONFUSUM.
Topics: Animals; Chromatography; Coleoptera; Dehydroepiandrosterone; Larva; Lipid Metabolism; Metabolism; Pregnenolone; Progesterone; Research; Sterols; Tribolium | 1964 |
SYNTHESIS OF PREGNENOLONE SULFATE, DEHYDROISOANDROSTERONE SULFATE, 17-ALPHA-HYDROXYPREGNENOLONE SULFATE AND DELTA-5-PREGNENETRIOL SULFATE BY THE NORMAL HUMAN ADRENAL GLAND.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Chromatography; Crystallization; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Metabolism; Pregnanediol; Pregnanetriol; Pregnenes; Pregnenolone; Sulfates; Tritium | 1965 |
SYNTHESIS OF STEROIDS IN THE NEWBORN HUMAN ADRENAL IN VITRO.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Cortex Hormones; Adrenal Glands; Aging; Carbon Isotopes; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydrocortisone; In Vitro Techniques; Infant, Newborn; Metabolism; NADP; Pregnenolone; Progesterone; Radiometry; Steroids | 1965 |
STUDIES WITH GLUCOSE 6-PHOSPHATE DEHYDROGENASE FROM HUMAN PLACENTA.
Topics: Androgens; Chemical Precipitation; Dehydroepiandrosterone; Enzyme Inhibitors; Enzymes; Estradiol; Female; Fluorometry; Follicle Stimulating Hormone; Glucose; Glucosephosphate Dehydrogenase; Humans; Luteinizing Hormone; NADP; Pharmacology; Phosphates; Placenta; Pregnancy; Pregnenolone; Spectrophotometry | 1965 |
ANDROGEN SYNTHESIS BY TESTICULAR TISSUE FROM A PATIENT WITH GONADAL INSUFFICIENCY.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Androgens; Biopsy; Chromatography; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; Hypogonadism; Leydig Cells; Male; Metabolism; Pathology; Pregnenolone; Sertoli Cells; Spermatozoa; Testis; Testosterone; Tritium | 1965 |
EXTRACTION OF STEROID CONJUGATES FROM URINE USING CHARCOAL AS AN ADSORBENT.
Topics: Adsorption; Androgens; Charcoal; Chromatography; Dehydroepiandrosterone; Estrone; Humans; Hydrocortisone; Metabolism; Pregnenolone; Progesterone; Steroids; Urine | 1965 |
STEROID TRANSFORMATIONS IN VITRO BY TESTICULAR TISSUE FROM TWO CASES OF TESTICULAR FEMINISATION.
Topics: 17-alpha-Hydroxypregnenolone; Androgen-Insensitivity Syndrome; Androgens; Chromatography; Cryptorchidism; Dehydroepiandrosterone; Disorders of Sex Development; Humans; In Vitro Techniques; Male; Metabolism; Pregnenolone; Progesterone; Steroids; Testicular Neoplasms; Testis; Testosterone | 1965 |
[INFECTION AND STEROIDS. IN VITRO BIOSYNTHESIS AND CONJUGATION OF STEROIDS IN INFECTION].
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Animals; Dehydroepiandrosterone; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Pregnenolone; Research; Salmonella Infections; Salmonella Infections, Animal; Steroids | 1965 |
METABOLISM OF PREGNENOLONE-3-SULPHATE IN THE PERFUSED DOG LIVER.
Topics: 17-alpha-Hydroxypregnenolone; Androstenols; Chromatography; Dehydroepiandrosterone; Dogs; Liver; Perfusion; Pregnenolone; Progesterone; Research; Sulfates; Testosterone | 1965 |
STEROID EFFECTS ON GLUCOSE-6-PHOSPHATE DEHYDROGENASE FROM BOVINE CORPORA LUTEA.
Topics: Androgens; Animals; Cattle; Corpus Luteum; Dehydroepiandrosterone; Enzyme Inhibitors; Estradiol; Female; Glucosephosphate Dehydrogenase; Humans; NADP; Pharmacology; Pregnenolone; Research; Spectrophotometry | 1965 |
STEROIDS AND STEROLS IN UMBILICAL CORD BLOOD.
Topics: Adrenal Glands; Blood; Cholesterol; Chromatography; Dehydroepiandrosterone; Endocrinology; Fetal Blood; Fetus; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Metabolism, Inborn Errors; Pregnenolone; Steroids; Sterols; Umbilical Cord | 1965 |
Isolation of dehydroepiandrosterone and 17alpha-hydroxy-delta5-pregenolone from the polycystic ovaries of the Stein-Leventhal syndrome.
Topics: Androgens; Cysts; Dehydroepiandrosterone; Female; Gonadotropins; Gonadotropins, Pituitary; Humans; Microchemistry; Pituitary Diseases; Pituitary Gland; Polycystic Ovary Syndrome; Pregnenolone | 1962 |
Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Cyclic AMP; Dehydroepiandrosterone; Desoxycorticosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Gene Expression; Hydroxycholesterols; Phosphoproteins; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 11-beta-Hydroxylase; Zona Fasciculata; Zona Reticularis | 2003 |
A capillary gas chromatography/mass spectrometric method for the quantification of hydroxysteroids in human plasma.
Topics: Biotransformation; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Humans; Hydroxysteroids; Molecular Structure; Pregnenolone; Radioimmunoassay; Reproducibility of Results; Spectrophotometry; Time Factors | 2004 |
Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons.
Topics: Animals; Aromatase; Calcium Signaling; Cholesterol; Dehydroepiandrosterone; Estradiol; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Microscopy, Immunoelectron; N-Methylaspartate; Neurons; Pregnenolone; Rats; Rats, Wistar; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone | 2004 |
Enhanced antidepressant efficacy of sigma1 receptor agonists in rats after chronic intracerebroventricular infusion of beta-amyloid-(1-40) protein.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antidepressive Agents; Brain; Cinnamates; Conditioning, Psychological; Cyclopropanes; Dehydroepiandrosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Fear; Injections, Intraventricular; Male; Peptide Fragments; Phenazocine; Pregnenolone; Progesterone; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stress, Psychological | 2004 |
Synthesis of [19- 2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates.
Topics: Androstanes; Combinatorial Chemistry Techniques; Dehydroepiandrosterone; Deuterium; Molecular Structure; Pregnanolone; Pregnenolone | 2004 |
Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome.
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Female; Follicular Phase; Humans; Hydrocortisone; Luteal Phase; Pregnanolone; Pregnenolone; Premenstrual Syndrome; Progesterone; Testosterone | 2004 |
Plasma levels of 7-hydroxylated dehydroepiandrosterone (DHEA) metabolites and selected amino-thiols as discriminatory tools of Alzheimer's disease and vascular dementia.
Topics: 17-alpha-Hydroxypregnenolone; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dementia, Vascular; Dipeptides; Female; Glutathione; Homocysteine; Humans; Logistic Models; Male; Middle Aged; Predictive Value of Tests; Pregnenolone; Radioimmunoassay; Sensitivity and Specificity; Sex Factors; Statistics, Nonparametric; Sulfhydryl Compounds | 2004 |
Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
Topics: 5-alpha-Dihydroprogesterone; Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Female; Finasteride; Gender Identity; Gonadal Steroid Hormones; Neurons; Ovariectomy; Pregnenolone; Progesterone; Propylamines; Protein Isoforms; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Synaptic Transmission; Time Factors | 2004 |
Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.
Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Gas Chromatography-Mass Spectrometry; Male; Pregnenolone; Rats; Rats, Sprague-Dawley | 2004 |
Modulation of bradykinin-induced calcium changes in SH-SY5Y cells by neurosteroids and sigma receptor ligands via a shared mechanism.
Topics: Binding Sites; Bradykinin; Calcium; Calcium Signaling; Cell Line, Tumor; Dehydroepiandrosterone; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Fura-2; Haloperidol; Humans; Narcotics; Neuroblastoma; Pentazocine; Pregnenolone; Time Factors | 2004 |
Urinary analysis of 16(5alpha)-androsten-3alpha-ol by gas chromatography/combustion/isotope ratio mass spectrometry: implications in anti-doping analysis.
Topics: Androstenols; Chromatography, Gas; Dehydroepiandrosterone; Doping in Sports; Humans; Indicators and Reagents; Mass Spectrometry; Pregnenolone; Reference Standards; Reference Values; Reproducibility of Results; Testosterone | 2004 |
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain.
Topics: Animals; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Male; Morphine Dependence; Pregnenolone; Progesterone; Random Allocation; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2004 |
Testicular and blood steroid levels in aged men.
Topics: Aged; Aged, 80 and over; Aging; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Pregnenolone; Progesterone; Reference Values; Sex Hormone-Binding Globulin; Steroids; Testis; Testosterone | 2004 |
Age-related expression of sigma1 receptors and antidepressant efficacy of a selective agonist in the senescence-accelerated (SAM) mouse.
Topics: Age Factors; Aging; Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Blotting, Northern; Brain; Cinnamates; Cyclopropanes; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Gene Expression Regulation; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Phenazocine; Pregnenolone; Progesterone; Radioligand Assay; Receptors, sigma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tritium | 2005 |
The involvement of dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) in blocking the therapeutic effect of electroconvulsive shocks in an animal model of depression.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Brain Chemistry; Cytosol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Electroshock; Hydrocortisone; Liver; Male; Nerve Tissue Proteins; Pregnenolone; Rats; Rats, Inbred Strains; Sulfotransferases | 2005 |
Novel type of Gq/11 protein-coupled neurosteroid receptor sensitive to endocrine disrupting chemicals in mast cell line (RBL-2H3).
Topics: Animals; Behavior, Animal; beta-N-Acetylhexosaminidases; Binding, Competitive; Cattle; Cell Line, Tumor; Cell Membrane; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estradiol; Estrenes; Fluorescein-5-isothiocyanate; GTP-Binding Protein alpha Subunits, Gi-Go; Leukemia, Basophilic, Acute; Macrocyclic Compounds; Male; Mast Cells; Mice; Nociceptors; Oligonucleotides, Antisense; Oxazoles; Pain; Pertussis Toxin; Phenols; Phosphodiesterase Inhibitors; Pregnenolone; Pyrrolidinones; Receptors, Steroid; Serum Albumin, Bovine; Type C Phospholipases | 2005 |
Pregnenolone and dehydroepiandrosterone administration in neonatal rats alters the immunoreactivity of hippocampal synapsin I, neuropeptide Y and glial fibrillary acidic protein at post-puberty.
Topics: Animals; Animals, Newborn; Dehydroepiandrosterone; Dentate Gyrus; Dynorphins; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Neuropeptide Y; Pregnenolone; Rats; Rats, Sprague-Dawley; Sexual Maturation; Synapsins | 2005 |
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors | 2005 |
The effects of the neurosteroids: pregnenolone, progesterone and dehydroepiandrosterone on muscarinic receptor-induced responses in Xenopus oocytes expressing M1 and M3 receptors.
Topics: Acetylcholine; Animals; Calcium; Chloride Channels; Cloning, Molecular; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Female; Indoles; Ion Channel Gating; Maleimides; Muscarinic Antagonists; Oocytes; Patch-Clamp Techniques; Pregnenolone; Progesterone; Protein Kinase C; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; RNA, Complementary; Xenopus laevis | 2005 |
Enzymic conversion of 3beta-hydroxy-5-ene-steroids and their sulfates to 3-oxo-4-ene-steroids for increasing sensitivity in LC-APCI-MS.
Topics: Androstenedione; Chemistry, Pharmaceutical; Cholesterol Oxidase; Chromatography, Liquid; Dehydroepiandrosterone; Drug Industry; Humans; Mass Spectrometry; Pregnenolone; Progesterone; Sensitivity and Specificity; Steroids; Sulfates; Testosterone; Time Factors | 2005 |
The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3beta,17beta-androstenediol, and testosterone in human serum using gas chromatography-mass spectrometry.
Topics: Adolescent; Adult; Androstenediol; Child; Dehydroepiandrosterone; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Pregnenolone; Reference Values; Testosterone | 2005 |
[Determination of unconjugated neurosteroids in rat brain regions by liquid chromatography-negative atmospheric pressure ionization mass spectrometry].
Topics: Amygdala; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Dehydroepiandrosterone; Hippocampus; Hypothalamus; Male; Mass Spectrometry; Nucleus Accumbens; Prefrontal Cortex; Pregnenolone; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2005 |
A study of a dendritic marker, microtubule-associated protein 2 (MAP-2), in rats neonatally treated neurosteroids, pregnenolone and dehydroepiandrosterone (DHEA).
Topics: Animals; Animals, Newborn; Biomarkers; Brain; Cell Differentiation; Dehydroepiandrosterone; Dendrites; Female; Hippocampus; Male; Microtubule-Associated Proteins; Neural Pathways; Nucleus Accumbens; Pregnenolone; Rats; Rats, Sprague-Dawley; Up-Regulation | 2005 |
Characterization of the guinea pig 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4-isomerase expressed in the adrenal gland and gonads.
Topics: Adrenal Glands; Amino Acid Sequence; Animals; Dehydroepiandrosterone; DNA, Complementary; Female; Guinea Pigs; Male; Molecular Sequence Data; Multienzyme Complexes; Ovary; Phylogeny; Pregnenolone; Progesterone Reductase; RNA, Messenger; Steroid Isomerases; Testis | 2005 |
Involvement of GABAA receptor modulating neuroactive steroids in patients with social phobia.
Topics: Adult; Aged; Allosteric Regulation; Blood Platelets; Brain; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; GABA-A Receptor Antagonists; Humans; Hydrocortisone; Male; Middle Aged; Phobic Disorders; Pregnenolone; Receptors, GABA-A; Reference Values; Statistics as Topic | 2005 |
Dehydroepiandrosterone (DHEA) attenuates cocaine-seeking behavior in the self-administration model in rats.
Topics: Affect; Animals; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Cocaine-Related Disorders; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dopamine; Dose-Response Relationship, Drug; Male; Nerve Tissue Proteins; Pregnenolone; Rats; Rats, Sprague-Dawley; Reward; Self Administration; Serotonin | 2006 |
[Effects of morphine dependence on the levels of neurosteroids in rat brain].
Topics: Amygdala; Animals; Brain; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hypothalamus; Male; Morphine Dependence; Nucleus Accumbens; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley | 2005 |
Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.
Topics: Adult; Aging; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Isomerism; Luteal Phase; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA-A | 2006 |
Strain differences of neurosteroid levels in mouse brain.
Topics: Animals; Brain Chemistry; Dehydroepiandrosterone; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Pregnenolone; Species Specificity; Steroids | 2006 |
Capillary liquid chromatography-microchip atmospheric pressure chemical ionization-mass spectrometry.
Topics: Atmospheric Pressure; Chromatography, Liquid; Dehydroepiandrosterone; Mass Spectrometry; Microarray Analysis; Miniaturization; Pregnenolone; Progesterone; Testosterone | 2006 |
The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Disease Progression; Gas Chromatography-Mass Spectrometry; Humans; Male; Prefrontal Cortex; Pregnanolone; Pregnenolone | 2006 |
Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.
Topics: Amino Acid Sequence; Animals; Breast; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Nucleus; Cholesterol; Choriocarcinoma; Cloning, Molecular; Cytosol; Dehydroepiandrosterone; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Placenta; Pregnenolone; Protein Isoforms; Rats; Sequence Homology, Amino Acid; Skin; Subcellular Fractions; Substrate Specificity; Sulfates; Sulfotransferases; Transcription, Genetic | 2006 |
Differences in blood pregnenolone and dehydroepiandrosterone levels between schizophrenia patients and healthy subjects.
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Pregnenolone; Radioimmunoassay; Schizophrenia; Statistics as Topic; Time Factors | 2007 |
Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia.
Topics: Animals; Animals, Genetically Modified; Cricetinae; Dehydroepiandrosterone; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mesocricetus; Pregnanolone; Pregnenolone | 2007 |
Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Bacterial Proteins; Catalysis; Cholesterol; Computational Biology; Dehydroepiandrosterone; Detergents; Dihydrotestosterone; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Mutation; Mycobacterium tuberculosis; NAD; Osmolar Concentration; Phylogeny; Pregnenolone; Recombinant Proteins; Sterols; Substrate Specificity | 2007 |
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids | 2008 |
Involvement of sigma (sigma1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test.
Topics: Animals; Dehydroepiandrosterone; Ethylenediamines; Immobilization; Male; Mice; Mice, Inbred Strains; Motor Activity; Pregnenolone; Progesterone; Receptors, sigma; Tail | 2008 |
Effects of dehydroepiandrosterone on aldosterone release in rat zona glomerulosa cells.
Topics: Aldosterone; Angiotensin II; Animals; Calcium Signaling; Cells, Cultured; Culture Media; Cyclic AMP; Dehydroepiandrosterone; Pregnenolone; Rats; Zona Glomerulosa | 2008 |
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Topics: Adult; Anticonvulsants; Body Mass Index; Dehydroepiandrosterone; Desoxycorticosterone; Electroencephalography; Epilepsy; Estradiol; Female; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Premenstrual Syndrome; Progesterone; Receptors, GABA | 2008 |
Cerebrospinal fluid dehydroepiandrosterone levels are correlated with brain dehydroepiandrosterone levels, elevated in Alzheimer's disease, and related to neuropathological disease stage.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Dehydroepiandrosterone; Humans; Pregnenolone; Temporal Lobe | 2008 |
The key steroidogenic enzyme 3beta-hydroxysteroid dehydrogenase in Taenia solium and Taenia crassiceps (WFU).
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenediol; Animals; Chromatography, Thin Layer; Cricetinae; Culture Media; Cysticercus; Dehydroepiandrosterone; Estradiol; Intestines; Mice; Mice, Inbred BALB C; Nitroblue Tetrazolium; Pregnenolone; Staining and Labeling; Taenia; Testosterone | 2008 |
Baeyer-Villiger oxidation of DHEA, pregnenolone, and androstenedione by Penicillium lilacinum AM111.
Topics: Androstenedione; Biotransformation; Dehydroepiandrosterone; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Penicillium; Pregnenolone; Testolactone | 2008 |
Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids | 2008 |
Transformation of 5-ene steroids by the fungus Aspergillus tamarii KITA: mixed molecular fate in lactonization and hydroxylation pathways with identification of a putative 3beta-hydroxy-steroid dehydrogenase/Delta5-Delta4 isomerase pathway.
Topics: Aspergillus; Crystallography, X-Ray; Dehydroepiandrosterone; Hydroxylation; Multienzyme Complexes; Pregnenolone; Progesterone Reductase; Signal Transduction; Steroid Isomerases | 2009 |
Sex differences in neuroactive steroid levels in the nervous system of diabetic and non-diabetic rats.
Topics: Animals; Brain; Brain Diseases; Case-Control Studies; Dehydroepiandrosterone; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Estrous Cycle; Female; Gonadal Steroid Hormones; Male; Neuroprotective Agents; Peripheral Nervous System; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Factors; Spinal Cord; Testosterone | 2010 |
Studies on Baeyer-Villiger oxidation of steroids: DHEA and pregnenolone D-lactonization pathways in Penicillium camemberti AM83.
Topics: Androstenedione; Androsterone; Dehydroepiandrosterone; Lactones; Oxidation-Reduction; Penicillium; Pregnenolone; Progesterone | 2009 |
Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key.
Topics: Animals; Brain; Brain Chemistry; Cholesterol; Dehydroepiandrosterone; Male; Mice; Oxidation-Reduction; Pregnenolone; Rats; Rats, Sprague-Dawley | 2009 |
Altered levels of synapsin I, dopamine transporter, dynorphin A, and neuropeptide Y in the nucleus accumbens and striatum at post-puberty in rats treated neonatally with pregnenolone or DHEA.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Corpus Striatum; Dehydroepiandrosterone; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dynorphins; Immunohistochemistry; Nerve Tissue Proteins; Neural Pathways; Neurons; Neuropeptide Y; Nucleus Accumbens; Pregnenolone; Rats; Rats, Sprague-Dawley; Synapsins; Time; Up-Regulation | 2009 |
Metabolomics approach to anabolic steroid urine profiling of bovines treated with prohormones.
Topics: Anabolic Agents; Animals; Cattle; Chromatography, Liquid; Dehydroepiandrosterone; Mass Spectrometry; Metabolomics; Pregnenolone; Reproducibility of Results | 2009 |
Discovery of neurosteroid glucuronides in mouse brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Corticosterone; Dehydroepiandrosterone; Glucuronides; Male; Mice; Pregnenolone; Rats; Tandem Mass Spectrometry | 2009 |
A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: identification, characterization, and ontogenic study.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cytosol; Dehydroepiandrosterone; Female; Gene Expression Regulation, Developmental; Hydrogen-Ion Concentration; Hydroxysteroids; Kinetics; Larva; Male; Molecular Sequence Data; Pregnenolone; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Sulfotransferases; Xenobiotics; Zebrafish; Zebrafish Proteins | 2009 |
Screening of ovarian steroidogenic pathway in Ciona intestinalis and its modulation after tributyltin exposure.
Topics: 17-Hydroxysteroid Dehydrogenases; Adrenodoxin; Animals; Cholesterol; Ciona intestinalis; Corticosterone; Dehydroepiandrosterone; Endocrine Disruptors; Estradiol; Estrone; Female; Ferredoxin-NADP Reductase; Gas Chromatography-Mass Spectrometry; Gene Expression; Gonadal Steroid Hormones; Ovary; Pregnenolone; Progesterone; Testosterone; Trialkyltin Compounds | 2010 |
Testosterone synthesized in cultured human SZ95 sebocytes derives mainly from dehydroepiandrosterone.
Topics: 17-alpha-Hydroxyprogesterone; Cell Line, Transformed; Cholesterol; Chorionic Gonadotropin; Colforsin; Cyclic CMP; Dehydroepiandrosterone; Dexamethasone; Female; Fibroblast Growth Factor 9; Humans; Hydroxycholesterols; Insulin; Insulin-Like Growth Factor I; Interleukin-1beta; Pregnenolone; Progesterone; Sebaceous Glands; Testosterone | 2010 |
Neurosteroid transport by the organic solute transporter OSTα-OSTβ.
Topics: Adrenal Glands; Animals; Biological Transport, Active; Brain Chemistry; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Immunohistochemistry; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdissection; Neurotransmitter Agents; Oocytes; Pregnenolone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Xenopus laevis | 2010 |
Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
Topics: Allosteric Regulation; Animals; Brain; Dehydroepiandrosterone; Male; Morphine; Neurotransmitter Agents; Opioid-Related Disorders; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Decreased cytochrome c oxidase IV expression reduces steroidogenesis.
Topics: Animals; Chlorocebus aethiops; COS Cells; Dehydroepiandrosterone; Down-Regulation; Electron Transport Complex IV; Female; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Mice; Mice, Inbred C57BL; Pregnenolone; Progesterone; Random Allocation; Smoking; Steroids | 2011 |
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.
Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2011 |
Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.
Topics: Androstenedione; Androstenes; Androstenols; Animals; Antineoplastic Agents, Hormonal; Carcinoma; Cell Line, Tumor; Dehydroepiandrosterone; Female; Humans; Indomethacin; Male; Mice; Orchiectomy; Pregnenolone; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Up-Regulation | 2011 |
The influence of trilostane on steroid hormone metabolism in canine adrenal glands and corpora lutea-an in vitro study.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Animals; Autoradiography; Corpus Luteum; Dehydroepiandrosterone; Dihydrotestosterone; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Pregnenolone | 2012 |
Neurosteroid PREGS protects neurite growth and survival of newborn neurons in the hippocampal dentate gyrus of APPswe/PS1dE9 mice.
Topics: Alzheimer Disease; Animals; Animals, Newborn; Dehydroepiandrosterone; Dentate Gyrus; Disease Models, Animal; Humans; Male; Mice; Mice, Transgenic; Neural Stem Cells; Neurites; Neurogenesis; Pregnenolone | 2012 |
Patterns of endogenous steroids in apathetic refugee children are compatible with long-term stress.
Topics: 17-alpha-Hydroxyprogesterone; Activities of Daily Living; Adolescent; Child; Chromatography, Liquid; Cortisone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Male; Mass Spectrometry; Pregnenolone; Refugees; Steroids; Stress, Psychological; Sweden; Syndrome; Time Factors; Unconscious, Psychology | 2012 |
Synthesis and in vitro antiproliferative evaluation of some ring B abeo-sterols.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cholesterol; Dehydroepiandrosterone; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Pregnenolone; Sitosterols; Sterols; Structure-Activity Relationship; Thiosemicarbazones | 2012 |
Inhibition by pregnenolone sulphate, a metabolite of the neurosteroid pregnenolone, of voltage-gated sodium channels expressed in Xenopus oocytes.
Topics: Animals; Cells, Cultured; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; NAV1.2 Voltage-Gated Sodium Channel; Oocytes; Pregnenolone; Sodium Channel Blockers; Xenopus laevis | 2012 |
[Correlation between neurotransmitters and neurosteroids and premenstrual syndrome patients of Gan-yang ascending syndrome and Gan-qi stagnation syndrome].
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Humans; Luteal Phase; Medicine, Chinese Traditional; Middle Aged; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Premenstrual Syndrome; Progesterone; Young Adult | 2012 |
Simultaneous determination of pregnenolone sulphate, dehydroepiandrosterone and allopregnanolone in rat brain areas by liquid chromatography-electrospray tandem mass spectrometry.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Hippocampus; Male; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Steroid conversion with CYP106A2 - production of pharmaceutically interesting DHEA metabolites.
Topics: Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Hydroxylation; Pregnenolone; Stereoisomerism | 2014 |
Free and sulfated steroids secretion in postpubertal boars (Sus scrofa domestica).
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrone; Male; Pregnenolone; Sus scrofa; Swine; Testis; Testosterone | 2014 |
Effects of electroconvulsive therapy on plasma levels of neuroactive steroids in inpatients with major depression.
Topics: Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depressive Disorder, Treatment-Resistant; Electroconvulsive Therapy; Estradiol; Female; Humans; Inpatients; Male; Neurotransmitter Agents; Pregnenolone; Progesterone; Prospective Studies; Testosterone; Young Adult | 2014 |
Endoxifen and other metabolites of tamoxifen inhibit human hydroxysteroid sulfotransferase 2A1 (hSULT2A1).
Topics: Catalysis; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Pregnenolone; Proton Magnetic Resonance Spectroscopy; Sulfotransferases; Tamoxifen | 2014 |
Structures of human steroidogenic cytochrome P450 17A1 with substrates.
Topics: 17-alpha-Hydroxyprogesterone; Androstenes; Androstenols; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Dehydroepiandrosterone; Estrogens; Heme; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Structure; Mutation; Oxidation-Reduction; Pregnenolone; Progesterone; Protein Binding; Protein Structure, Secondary; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity; Testosterone | 2014 |
Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
Topics: Adult; Aged; Autopsy; Biomarkers; Bipolar Disorder; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Gyrus Cinguli; Humans; Male; Middle Aged; Parietal Lobe; Pilot Projects; Pregnanolone; Pregnenolone; Schizophrenia; Suicide; Young Adult | 2015 |
Hormone abnormalities in patients with severe and chronic pain who fail standard treatments.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Biomarkers; Chronic Pain; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Male; Middle Aged; Pregnenolone; Progesterone; Testosterone; Treatment Failure | 2015 |
2β- and 16β-hydroxylase activity of CYP11A1 and direct stimulatory effect of estrogens on pregnenolone formation.
Topics: Androstenedione; Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Desoxycorticosterone; Enzyme Assays; Escherichia coli; Estradiol; Estrone; Gene Expression; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Plasmids; Pregnenolone; Recombinant Proteins; Solutions; Substrate Specificity; Testosterone; Transformation, Bacterial | 2015 |
Exploratory study of the association of steroid profiles in stimulated ovarian follicular fluid with outcomes of IVF treatment.
Topics: Adult; Androstenedione; Dehydroepiandrosterone; Estradiol; Estrone; Female; Fertilization in Vitro; Follicular Fluid; Humans; Infertility, Female; Live Birth; Oocytes; Ovulation Induction; Pregnancy; Pregnenolone; Prospective Studies; Steroids; Tandem Mass Spectrometry; Testosterone; Young Adult | 2016 |
Domestication Effects on Stress Induced Steroid Secretion and Adrenal Gene Expression in Chickens.
Topics: Adrenal Glands; Animals; Aromatase; Chickens; Chromatography, Supercritical Fluid; Corticosterone; Dehydroepiandrosterone; Female; Male; Pregnenolone; Pro-Opiomelanocortin; Real-Time Polymerase Chain Reaction; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases; Steroids; Stress, Physiological; Tandem Mass Spectrometry; Up-Regulation | 2015 |
Term neonates with infection and shock display high cortisol precursors despite low levels of normal cortisol.
Topics: Cortisone; Dehydroepiandrosterone; Humans; Hydrocortisone; Infant, Newborn; Infant, Newborn, Diseases; Infections; Pregnenolone; Progesterone; Shock | 2016 |
Unveiling the crucial intermediates in androgen production.
Topics: 17-alpha-Hydroxypregnenolone; Androgens; Biocatalysis; Biosynthetic Pathways; Dehydroepiandrosterone; Humans; Hydrogen Bonding; Hydroxylation; Models, Chemical; Models, Molecular; Molecular Structure; Pregnenolone; Protein Conformation; Spectrophotometry; Steroid 17-alpha-Hydroxylase; Substrate Specificity; Temperature | 2015 |
Daily profiles of steroid hormones and their metabolites related to food intake.
Topics: Adult; Circadian Rhythm; Dehydroepiandrosterone; Eating; Estradiol; Female; Ghrelin; Humans; Hydrocortisone; Pregnenolone; Progesterone; Sex Hormone-Binding Globulin | 2015 |
Is migraine a consequence of a loss of neurohormonal and metabolic integrity? A new hypothesis.
Topics: Adolescent; Adult; Aged; Androgens; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Female; Hormone Replacement Therapy; Humans; Male; Middle Aged; Migraine Disorders; Pregnenolone; Progesterone; Progestins; Testosterone; Young Adult | 2015 |
Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Arylsulfotransferase; Carcinogens; Cell Line; Comet Assay; Dehydroepiandrosterone; DNA Damage; Gene Expression Regulation; Hepatocytes; Humans; Hymecromone; Liver; Pregnenolone; Rats; Sulfotransferases | 2016 |
Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis.
Topics: Adult; Biomarkers; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Pregnanolone; Pregnenolone; Recurrence | 2016 |
A Comparison of Salivary Steroid Levels during Diagnostic Tests for Adrenal Insufficiency.
Topics: Adrenal Insufficiency; Adult; Chromatography, Liquid; Cosyntropin; Dehydroepiandrosterone; Diagnostic Tests, Routine; Healthy Volunteers; Hormones; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnenolone; Saliva | 2016 |
Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics.
Topics: Adolescent; Adult; Aged; Alcoholism; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Pregnenolone; Young Adult | 2016 |
Serum levels of cholesterol, pregnenolone, DHEA, and their sulfate conjugates based on sex and pubertal stage in adolescents.
Topics: Adolescent; Child; Cholesterol; Dehydroepiandrosterone; Female; Humans; Male; Mass Spectrometry; Pregnenolone; Puberty; Sex Characteristics; Sulfates | 2016 |
Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Child; Child, Preschool; Dehydroepiandrosterone; Estradiol Dehydrogenases; Homeostasis; Humans; Ichthyosis, X-Linked; Middle Aged; Pregnenolone; Steroid 17-alpha-Hydroxylase; Steroids; Steryl-Sulfatase; Sulfates; Young Adult | 2016 |
Serum DHEA-S concentration correlates with clinical symptoms and neurocognitive function in patients with bipolar II disorder: A case-controlled study.
Topics: Adolescent; Adult; Bipolar Disorder; Case-Control Studies; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Pregnenolone; Psychiatric Status Rating Scales; Young Adult | 2017 |
Cortisol precursors in neonates with vasopressor-resistant hypotension in relationship to demographic characteristics.
Topics: 17-alpha-Hydroxypregnenolone; Cohort Studies; Dehydroepiandrosterone; Drug Resistance; Female; Gestational Age; Humans; Hydrocortisone; Hypotension; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Pregnenolone; Risk Factors; Treatment Failure; Vasoconstrictor Agents | 2018 |
Gender differences in susceptibility to schizophrenia: Potential implication of neurosteroids.
Topics: Adult; Case-Control Studies; China; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Disease Susceptibility; Female; Humans; Hydrocortisone; Male; Middle Aged; Neurotransmitter Agents; Pregnenolone; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Sex Factors | 2017 |
Equine fetal adrenal, gonadal and placental steroidogenesis.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adrenal Cortex Hormones; Adrenal Glands; Androstenedione; Animals; Aromatase; Cholesterol Side-Chain Cleavage Enzyme; Dehydroepiandrosterone; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Gonadal Steroid Hormones; Horses; Male; Multienzyme Complexes; Ovary; Placenta; Pregnancy; Pregnenolone; Progesterone Reductase; Steroid 17-alpha-Hydroxylase; Steroid Isomerases; Testis | 2017 |
Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Biomarkers, Pharmacological; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Male; Metabolic Networks and Pathways; Pregnanolone; Pregnenolone; Progesterone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2018 |
Effects of genetic polymorphisms on the sulfation of dehydroepiandrosterone and pregnenolone by human cytosolic sulfotransferase SULT2A1.
Topics: Dehydroepiandrosterone; Humans; Kinetics; Mutagenesis, Site-Directed; Polymorphism, Single Nucleotide; Pregnenolone; Recombinant Proteins; Sulfotransferases | 2018 |
Characterizing the steroidal milieu in amniotic fluid of mid-gestation: A LC-MS/MS study.
Topics: 17-alpha-Hydroxypregnenolone; Amniotic Fluid; Androsterone; Chromatography, Liquid; Dehydroepiandrosterone; Epitestosterone; Estriol; Estrone; Female; Gestational Age; Humans; Male; Pregnancy; Pregnancy Trimester, Second; Pregnenolone; Steroids; Tandem Mass Spectrometry | 2019 |
Cloning, prokaryotic expression and function of the Bufo bufo gargarizans 3β-hydroxysteroid dehydrogenase (3βHSD) gene.
Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Amphibian Proteins; Animals; Bufo bufo; Cloning, Molecular; Dehydroepiandrosterone; Escherichia coli; Gene Expression; Genetic Vectors; Isoelectric Point; Kinetics; Molecular Weight; NAD; Open Reading Frames; Phylogeny; Pregnenolone; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 2018 |
Effect of SULT2B1 genetic polymorphisms on the sulfation of dehydroepiandrosterone and pregnenolone by SULT2B1b allozymes.
Topics: Dehydroepiandrosterone; Humans; Isoenzymes; Polymorphism, Single Nucleotide; Pregnenolone; Sulfotransferases | 2019 |
[Synthesis and evaluation of N-alkynylaminosteroids as potential CYP450 17A1 inhibitors].
Topics: Dehydroepiandrosterone; Enzyme Inhibitors; Pregnenolone; Steroid 17-alpha-Hydroxylase | 2019 |
Plasma concentrations of steroid precursors, steroids, neuroactive steroids, and neurosteroids in healthy neonatal foals from birth to 7 days of age.
Topics: Animals; Animals, Newborn; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Female; Horses; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pregnenolone; Progesterone; Prospective Studies | 2019 |
Rapid and structure-specific cellular uptake of selected steroids.
Topics: Androgens; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Humans; Kinetics; Pregnenolone; Progesterone; Steroids; Tandem Mass Spectrometry | 2019 |
A cross-sectional survey of adrenal steroid hormones among overweight/obese boys according to puberty stage.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Cortex Hormones; Age Factors; Androstenedione; Child; Corticosterone; Cross-Sectional Studies; Dehydroepiandrosterone; Humans; Male; Organ Size; Overweight; Pediatric Obesity; Pregnenolone; Puberty; Puberty, Precocious; Sex Hormone-Binding Globulin; Testis; Testosterone | 2019 |
Tracing steroidogenesis in prostate biopsy samples to unveil prostate tissue androgen metabolism characteristics and potential clinical application.
Topics: Aged; Aged, 80 and over; Androgens; Biopsy; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Humans; Male; Mass Spectrometry; Pregnenolone; Prostatic Neoplasms; Steroids | 2021 |
Steroid profiling and genetic variants in Chinese women with gestational diabetes mellitus.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Alleles; Aromatase; China; Dehydroepiandrosterone; Diabetes, Gestational; Estriol; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Polymorphism, Single Nucleotide; Pregnancy; Pregnenolone; Risk; Steroids; Testosterone | 2021 |
Mechanism of the Clinically Relevant E305G Mutation in Human P450 CYP17A1.
Topics: Androgens; Androstenedione; Catalytic Domain; Dehydroepiandrosterone; Humans; Hydrogen Bonding; Hydroxylation; Mutation; Polymorphism, Single Nucleotide; Pregnenolone; Progesterone; Spectrum Analysis, Raman; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity; Translocation, Genetic | 2021 |
Hydroxylation of pregnenolone and dehydroepiandrosterone by zygomycete Backusella lamprospora VKM F-944: selective production of 7α-OH-DHEA.
Topics: Dehydroepiandrosterone; Hydroxylation; Mucorales; Pregnenolone | 2022 |
Mechanism of action and neurotoxic effects of chronic exposure to bisphenol F in adult zebrafish.
Topics: Animals; Benzhydryl Compounds; Choline; Dehydroepiandrosterone; Ecosystem; Environmental Pollutants; Estradiol; Gonadotropin-Releasing Hormone; Hydrocortisone; Kynurenine; Ligands; Neurosteroids; Pregnenolone; Sulfates; Zebrafish | 2022 |
Follicle isolation methods reveal plasticity of granulosa cell steroidogenic capacity during mouse in vitro follicle growth.
Topics: 17-alpha-Hydroxypregnenolone; 17-alpha-Hydroxyprogesterone; Alginates; Alkaline Phosphatase; Androgens; Androstenedione; Animals; Carrier Proteins; Dehydroepiandrosterone; Estradiol; Female; Granulosa Cells; Humans; Inhibins; Lyases; Mice; Pregnenolone; Progesterone; Theca Cells | 2022 |
Measurement of hair thyroid and steroid hormone concentrations in the rat evidence endocrine disrupting potential of a low dose mixture of polycyclic aromatic hydrocarbons.
Topics: Androstenedione; Animals; Corticosterone; Dehydroepiandrosterone; Female; Hair; Hydroxyprogesterones; Polycyclic Aromatic Hydrocarbons; Pregnenolone; Rats; Thyroid Gland; Thyroid Hormones; Thyronines | 2022 |
Recombinant Extracellular Cholesterol Oxidase from Nocardioides simplex.
Topics: Actinobacteria; Cholestanols; Cholesterol Oxidase; Dehydroepiandrosterone; Hydrogen Peroxide; Phytosterols; Pregnenolone; Steroids | 2022 |
Steroid Profiling in the Amniotic Fluid: Reference Range for 12 Steroids and Interest in 21-Hydroxylase Deficiency.
Topics: 17-alpha-Hydroxyprogesterone; Amniotic Fluid; Chromatography, Liquid; Corticosterone; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Pregnancy; Pregnenolone; Reference Values; Steroids; Tandem Mass Spectrometry; Testosterone | 2023 |
Oxytocin modulates steroidogenesis-associated genes and estradiol levels in the placenta.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Female; Oxytocin; Placenta; Pregnancy; Pregnenolone; Progesterone; Rats; Steroids | 2023 |