dehydroepiandrosterone has been researched along with pregnanolone in 98 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (6.12) | 18.7374 |
| 1990's | 10 (10.20) | 18.2507 |
| 2000's | 52 (53.06) | 29.6817 |
| 2010's | 28 (28.57) | 24.3611 |
| 2020's | 2 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Bell, JB | 1 |
| Abraham, GE; Chang, RJ | 1 |
| Schindler, AE; Wuchter, J | 1 |
| Frederik, PM; Klepper, D | 1 |
| Lieberman, S | 1 |
| Gielen, JE; Kremers, P; Pasleau, F | 1 |
| Baulieu, EE; Mahé, V; Monnet, FP; Robel, P | 1 |
| Holsboer, F; Parlow, F; Vedder, H; Zieglgänsberger, W | 1 |
| Chen, HC; Driscoll, WJ; Martin, BM; Strott, CA | 1 |
| Baulieu, EE; Corpéchot, C; Eychenne, B; Haug, M; Perché, F; Robel, P; Young, J | 1 |
| Kulkarni, SK; Reddy, DS | 2 |
| Bonanno, G; Raiteri, M; Sala, R; Schmid, G | 1 |
| Bernardi, F; Casarosa, E; Genazzani, AR; Luisi, M; Luisi, S; Nappi, RE; Palumbo, M; Petraglia, F; Purdy, RH; Salvestroni, C; Tonetti, A | 1 |
| di Michele, F; Hermann, B; Holsboer, F; Pasini, A; Romeo, E; Rupprecht, R; Spalletta, G; Ströhle, A | 1 |
| Holsboer, F; Rupprecht, R | 1 |
| Baumann, N; Eychenne, B; Lachapelle, F; Le Goascogne, C; Robel, P; Tonon, MC | 1 |
| Bernardi, F; Cento, RM; Genazzani, AD; Genazzani, AR; Lanzone, A; Luisi, M; Luisi, S; Petraglia, F; Pezzani, I; Spada, RS | 1 |
| Bernardi, F; Genazzani, AR; Luisi, M; Luisi, S; Monteleone, P | 1 |
| Gilmore, JH; Jarskog, LF; Lauder, JM; Lieberman, JA; Marx, CE; Morrow, AL | 1 |
| Biggio, G; Littera, M; Papi, G; Pisu, MG; Purdy, RH; Sanna, E; Serra, M; Tuveri, F; Usala, L | 1 |
| Fitzgerald, RL; Koob, GF; Purdy, RH; Rivera, JD; Vallée, M | 1 |
| Jhangri, GS; Le Mellédo, JM; Semeniuk, T | 1 |
| Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A | 1 |
| Koob, GF; Le Moal, M; Mayo, W; Vallée, M | 1 |
| Engel, SR; Grant, KA | 1 |
| Mellon, SH; Vaudry, H | 1 |
| Bernardi, F; Casarosa, E; Cobellis, L; Genazzani, AR; Luisi, M; Luisi, S; Monteleone, P; Petraglia, F; Stomati, M | 1 |
| Bellavance, F; Chrapko, W; Lara, N; Le Mellédo, JM; McManus, K; Tait, GR | 1 |
| Bicíková, M; Hill, M; Stárka, L; Tallová, J; Vrbíková, J | 1 |
| Heydari, B; Le Mellédo, JM | 1 |
| van Broekhoven, F; Verkes, RJ | 1 |
| Hermann, B; Holsboer, F; Keck, ME; Landgraf, R; Morrow, AL; Rupprecht, R; Ströhle, A; Wigger, A | 1 |
| Bernardi, F; Ceccarelli, C; Genazzani, AR; Luisi, S; Palumbo, M; Pieri, M; Pluchino, N; Stomati, M | 1 |
| Abbiati, I; Ferdeghini, F; Genazzani, AR; Luisi, S; Nappi, RE; Polatti, F | 1 |
| Borgioli, G; Casarosa, E; di Bono, I; Gambacciani, M; Genazzani, AD; Genazzani, AR; Lombardi, I; Luisi, M; Palumbo, M | 1 |
| Galderisi, S; Maj, M; Monteleone, P; Mucci, A; Piegari, G; Sorrentino, D | 1 |
| Auchus, RJ; Flück, CE; Miller, WL | 1 |
| Colurcio, B; De Filippis, G; Genazzani, AR; Luisi, M; Maj, M; Monteleone, P | 1 |
| Bicíková, M; Budesínský, M; Cerný, I; Hampl, R; Hill, M; Pouzar, V | 1 |
| Alexaki, VI; Castanas, E; Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Margioris, AN; Tsatsanis, C | 1 |
| Bernardi, F; Casarosa, E; Genazzani, AR; Liut, M; Lombardi, I; Luisi, S; Monteleone, P; Palumbo, M; Petraglia, F; Quirici, B | 1 |
| Bernardi, F; Casarosa, E; Genazzani, AD; Genazzani, AR; Luisi, S; Palumbo, M; Pluchino, N | 1 |
| Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Margioris, AN; Stournaras, C; Tsatsanis, C; Vardouli, L | 1 |
| Cerný, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Popov, P; Pouzar, V; Stárka, L; Vrbíková, J | 1 |
| Alciati, A; Biggio, G; Brambilla, F; Mellado, C; Perini, G; Pisu, MG; Purdy, RH; Serra, M; Zanone, S | 1 |
| Bernardi, F; Casarosa, E; Gabbanini, M; Genazzani, AD; Genazzani, AR; Luisi, M; Palumbo, M; Picciarelli, G; Pieri, M; Pluchino, N | 1 |
| Bäckström, T; Biggio, G; Finn, DA; Janak, PH; Purdy, RH; Valenzuela, CF | 1 |
| Lucas, M; Maurice, T; Romieu, P | 1 |
| Casarosa, E; Genazzani, AR; Longobardi, N; Luisi, M; Maj, M; Martiadis, V; Monteleone, P; Serritella, C | 1 |
| Havlíková, H; Hill, M; Kancheva, L; Sobotka, V; Stárka, L | 1 |
| Papazafiri, P; Xilouri, M | 1 |
| Hou, YN; Wang, N; Wu, HH | 1 |
| Cerny, I; Havlíková, H; Hill, M; Kancheva, L; Kancheva, R; Pouzar, V; Stárka, L; Vrbíková, J | 1 |
| Charney, D; Gottschalk, C; Guidotti, A; Krystal, J; Paliwal, P; Pinna, G; Rasmusson, AM; Weisman, D | 1 |
| Blazer, DG; Butterfield, MI; Ervin, JF; Hulette, CM; Lieberman, JA; Marx, CE; Massing, MW; Shampine, LJ; Steffens, DC; Stevens, RD; Trost, WT | 1 |
| Alexaki, VI; Castanas, E; Charalampopoulos, I; Dermitzaki, E; Gravanis, A; Lasaridis, I; Margioris, AN; Minas, V; Stournaras, C; Tsatsanis, C; Vardouli, L | 1 |
| Avlonitis, N; Calogeropoulou, T; Papazafiri, P; Xilouri, M | 1 |
| Bicíková, M; Hampl, R | 1 |
| Hamann, M; Richter, A; Richter, F | 1 |
| Mellon, SH | 1 |
| Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M | 1 |
| Biggio, G; Concas, A; Marotto, MF; Marra, C; Marrosu, F; Melis, GB; Orrù, M; Paoletti, AM; Sogliano, C; Tuveri, A; Zedda, P | 1 |
| Casarosa, E; Freschi, L; Genazzani, AD; Genazzani, AR; Luisi, S; Ninni, F; Pluchino, N; Potì, E; Stomati, M; Valentino, V | 1 |
| Budziszewska, B; Jantas, D; Lason, W; Leskiewicz, M | 1 |
| Gurkovskaya, OV; Leonard, ST; Lewis, PB; Winsauer, PJ | 1 |
| Gurkovskaya, OV; Winsauer, PJ | 1 |
| Biggio, G; Morgan, ML; Pisu, MG; Rapkin, AJ; Rasgon, N; Serra, M | 1 |
| Calnaido, RP; Hamer, RM; Keefe, FJ; Kilts, JD; Marx, CE; Massing, MW; Morey, RA; Naylor, JC; Parke, G; Payne, VM; Shampine, LJ; Strauss, JL; Tupler, LA; Youssef, NA | 1 |
| Amato, RJ; He, H; Lewis, PB; Winsauer, PJ | 1 |
| Elfverson, M; Johansson, T; Nyberg, F; Zhou, Q | 1 |
| Forman, DE; Rasmusson, AM; Schnurr, PP; Scioli, E; Zukowska, Z | 1 |
| Hartmann, MF; Lignitz, S; Partsch, CJ; Pohlenz, J; Wudy, SA | 1 |
| Agustí, A; Cauli, O; Felipo, V; González-Usano, A | 1 |
| Gao, H; Qiao, MQ; Xia, T | 1 |
| Benelli, A; Carnevale, G; Cela, V; Di Viesti, V; Genazzani, AR; Giannini, A; Pluchino, N; Santoro, AN; Zanoli, P; Zavatti, M | 1 |
| Lucchi, C; Pinetti, D; Puia, G; Ravazzini, F; Rustichelli, C | 1 |
| Casarosa, E; Genazzani, AD; Genazzani, AR; Petignat, P; Pluchino, N; Santoro, A; Wenger, JM | 1 |
| Liberzon, I; Marx, CE; Sripada, RK; Welsh, RC | 1 |
| Cubero-Millán, I; Justicia-Martínez, F; León, J; Luna-Del-Castillo, JD; Machado-Casas, I; Molina-Carballo, A; Moreno-García, L; Moreno-Madrid, F; Muñoz-Hoyos, A; Uberos, J | 1 |
| Frye, CA; Koonce, CJ; Walf, AA | 1 |
| Gao, H; Ma, YX; Qiao, MQ; Shang, YZ; Xia, T; Zhang, HY | 1 |
| Eckert, A; Grimm, A; Lang, UE; Mensah-Nyagan, AG; Schmitt, K | 1 |
| Allen, TB; Bradford, DW; Brancu, M; Brunca, M; Hamer, RM; Kilts, JD; Marx, CE; Naylor, JC; Shampine, LJ; Strauss, JL; Szabo, ST; Youssef, NA | 1 |
| Amato, RJ; Hulin, MW; Lawrence, MN; Weed, PF; Winsauer, PJ | 1 |
| do Rego, JL; Vaudry, D; Vaudry, H | 1 |
| Ben Dor, R; Marx, CE; Rubinow, DR; Schmidt, PJ; Shampine, LJ | 1 |
| Bues, B; Calignano, A; Carotenuto, A; Cerillo, I; Mangone, G; Orefice, G; Orefice, N; Rehm, R; Saccà, F | 1 |
| Bičíková, M; Dušková, M; Hill, M; Mohr, P; Řípová, D; Šrámková, M; Stárka, L | 1 |
| Liang, JJ; Locci, A; Marx, CE; Nillni, YI; Pineles, SL; Pinna, G; Rasmusson, AM; Scioli-Salter, ER | 1 |
| Cai, H; Dougherty, GG; Haas, GL; Keshavan, M; Montrose, DM; Reddy, RD; Yao, JK; Zhou, X | 1 |
| Baulieu, EE; Froger, N; Lanfumey, L; Schverer, M; Villey, I | 1 |
| DeLarge, AF; Erwin, LL; Nilges, MR; Weed, PF; Winsauer, PJ | 1 |
| Anderson, GM; Gregor, K; Hamouda, M; King, MW; Nillni, YI; Pineles, SL; Pinna, G; Rasmusson, AM; Scioli-Salter, E; Valovski, I | 1 |
| Froger, N | 1 |
| Cosgrove, KP; Gueorguieva, R; McKee, SA; Mineur, YS; Peltier, MR; Petrakis, I; Picciotto, MR; Verplaetse, TL | 1 |
| Hammer, E; Hartmann, MF; Heckmann, M; Hübner, S; Ittermann, T; Krüger, EL; Sunny, DE; Völker, U; Wudy, SA | 1 |
17 review(s) available for dehydroepiandrosterone and pregnanolone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Studies on steroids in urine of the male newborn.
Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Arylsulfatases; Dehydroepiandrosterone; Glucuronidase; Humans; Hydrolysis; Hydroxyprogesterones; Infant, Newborn; Male; Pregnanediol; Pregnanes; Pregnanolone; Pregnenolone; Progesterone | 1975 |
Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives.
Topics: Dehydroepiandrosterone; Desoxycorticosterone; Estradiol; Humans; Neuroprotective Agents; Neurosecretory Systems; Pregnanolone; Pregnenolone; Progesterone; Steroids | 1999 |
Neurosteroids in learning and memory processes.
Topics: Animals; Dehydroepiandrosterone; Humans; Learning; Memory; Pregnanolone; Progesterone; Steroids | 2001 |
Neurosteroids and behavior.
Topics: Aggression; Animals; Anxiety; Behavior, Animal; Brain Chemistry; Dehydroepiandrosterone; Humans; Pregnanolone; Progesterone | 2001 |
Biosynthesis of neurosteroids and regulation of their synthesis.
Topics: Animals; Dehydroepiandrosterone; Humans; Nervous System; Pregnanolone | 2001 |
Clinical implications of circulating neurosteroids.
Topics: Aging; Alzheimer Disease; Dehydroepiandrosterone; Female; Humans; Male; Menopause; Menstrual Cycle; Pregnanolone | 2001 |
Neurosteroids in depression: a review.
Topics: Animals; Dehydroepiandrosterone; Depressive Disorder, Major; Humans; Neurotransmitter Agents; Pregnanolone; Selective Serotonin Reuptake Inhibitors | 2003 |
Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging.
Topics: Aging; Animals; Apoptosis; Dehydroepiandrosterone; Humans; Neuroimmunomodulation; Neurons; Pregnanolone | 2006 |
[Neurosteroids and their function].
Topics: Calcium Channels; Central Nervous System; Dehydroepiandrosterone; GABA Modulators; Humans; Pregnanolone; Receptors, GABA-A; Steroids | 2007 |
Neurosteroid regulation of central nervous system development.
Topics: Animals; Central Nervous System; Dehydroepiandrosterone; Humans; Pregnanolone; Pregnenolone; Progesterone; Steroids; Synaptic Transmission | 2007 |
Adaptation to extreme stress: post-traumatic stress disorder, neuropeptide Y and metabolic syndrome.
Topics: Adaptation, Physiological; Animals; Dehydroepiandrosterone; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Metabolic Syndrome; Mice; Models, Biological; Neuropeptide Y; Pregnanolone; Risk Factors; Stress Disorders, Post-Traumatic; Stress, Physiological; Testosterone | 2010 |
Advances in neurosteroids: role in clinical practice.
Topics: Affect; Aging; Behavior; Brain Injuries; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Menopause; Neurotransmitter Agents; Postpartum Period; Pregnancy; Pregnanolone; Premenstrual Syndrome; Progesterone; Reproduction | 2013 |
Neuroactive steroids and PTSD treatment.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Glucocorticoids; Humans; Pregnanolone; Steroids; Stress Disorders, Post-Traumatic; Stress, Psychological | 2017 |
Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases.
Topics: Animals; Dehydroepiandrosterone; Humans; Nervous System Diseases; Neurogenesis; Neuronal Plasticity; Neurotransmitter Agents; Pregnanolone; Pregnenolone | 2018 |
[New therapeutic avenues for neurosteroids in psychiatric diseases].
Topics: Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depression; Drugs, Investigational; Humans; Mental Disorders; Neuronal Plasticity; Neurosteroids; Pregnanolone; Psychiatry; Signal Transduction; Therapies, Investigational | 2019 |
Sex differences in progestogen- and androgen-derived neurosteroids in vulnerability to alcohol and stress-related disorders.
Topics: Affect; Alcohol-Related Disorders; Androgens; Dehydroepiandrosterone; Estradiol; Female; Humans; Male; Neurosteroids; Pregnanolone; Progesterone; Progestins; Sex Factors; Stress Disorders, Traumatic; Testosterone | 2021 |
8 trial(s) available for dehydroepiandrosterone and pregnanolone
| Article | Year |
|---|---|
Effects of antidepressant treatment on neuroactive steroids in major depression.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Dehydroepiandrosterone; Depressive Disorder; Female; Fluoxetine; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA; Steroids; Treatment Outcome | 1998 |
Neuroactive steroid changes in response to challenge with the panicogenic agent pentagastrin.
Topics: Adult; Arousal; Cross-Over Studies; Dehydroepiandrosterone; Double-Blind Method; Ethinyl Estradiol; Humans; Injections, Intravenous; Male; Panic; Panic Disorder; Pentagastrin; Pregnanolone; Premedication; Receptors, GABA-A; Reference Values | 2002 |
Effect of different hormonal replacement therapies on circulating allopregnanolone and dehydroepiandrosterone levels in postmenopausal women.
Topics: Administration, Cutaneous; Dehydroepiandrosterone; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Luteinizing Hormone; Middle Aged; Postmenopause; Pregnanolone; Progesterone; Progestins | 2003 |
Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa.
Topics: Adult; Analysis of Variance; Anorexia Nervosa; Body Weight; Dehydroepiandrosterone; Dexamethasone; Female; Humans; Hydrocortisone; Matched-Pair Analysis; Pregnanolone; Reference Values; Stimulation, Chemical | 2006 |
One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu.
Topics: Administration, Cutaneous; Administration, Oral; Dehydroepiandrosterone; Drug Therapy, Combination; Estradiol; Estrogen Replacement Therapy; Female; Humans; Middle Aged; Postmenopause; Pregnanolone; Progesterone; Steroids; Testosterone | 2008 |
Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women.
Topics: Brain; Dehydroepiandrosterone; Depressive Disorder, Major; Desoxycorticosterone; Estrogens; Female; Humans; Middle Aged; Postmenopause; Pregnanolone; Selective Serotonin Reuptake Inhibitors; Sertraline | 2010 |
The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting-state amygdala connectivity.
Topics: Adolescent; Adult; Amygdala; Case-Control Studies; Dehydroepiandrosterone; Double-Blind Method; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Movement; Neurotransmitter Agents; Oxygen; Pregnanolone; Rest; Statistics as Topic; Young Adult | 2014 |
DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.
Topics: Androsterone; Antidepressive Agents; Cross-Over Studies; Dehydroepiandrosterone; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Sex Factors; Treatment Outcome | 2015 |
73 other study(ies) available for dehydroepiandrosterone and pregnanolone
| Article | Year |
|---|---|
Studies of in vitro steroid metabolism by testis tissue from 'complete' and 'incomplete' forms of testicular feminization.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androstane-3,17-diol; Androstenediols; Androstenedione; Dehydroepiandrosterone; Humans; Hydroxyprogesterones; In Vitro Techniques; Kinetics; Male; Pregnanolone; Pregnenolone; Progesterone; Testis; Testosterone | 1975 |
Peripheral steroid levels in a patient with congenital absence of the uterus.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Amenorrhea; Androstenedione; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Follicular Phase; Humans; Hydrocortisone; Hydroxyprogesterones; Karyotyping; Luteal Phase; Luteinizing Hormone; Pregnanolone; Progesterone; Steroids; Testosterone; Uterus | 1975 |
The possibility of electron microscopic autoradiography of steroids after freeze drying of unfixed testes.
Topics: Androstanes; Androstenediols; Animals; Autoradiography; Dehydroepiandrosterone; Digitonin; Estradiol; Freeze Drying; Male; Microscopy, Electron; Pregnanolone; Rabbits; Rats; Testis; Testosterone | 1976 |
Pictorial endocrinology and empirical hormonology. The Sir Henry Dale lecture for 1986.
Topics: Animals; Dehydroepiandrosterone; Endocrinology; Estriol; Hormones; Humans; Molecular Conformation; Pregnanolone; Steroids | 1986 |
Competition between benzo[a]pyrene and various steroids for cytochrome P-450-dependent rat liver monooxygenases.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; Binding, Competitive; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pregnanolone; Progesterone; Rats; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Substrate Specificity; Testosterone | 1981 |
Neurosteroids, via sigma receptors, modulate the [3H]norepinephrine release evoked by N-methyl-D-aspartate in the rat hippocampus.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Guanidines; Haloperidol; Hippocampus; Kinetics; N-Methylaspartate; Norepinephrine; Ovariectomy; Pertussis Toxin; Piperazines; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stereotaxic Techniques; Virulence Factors, Bordetella | 1995 |
Neurosteroids do not regulate proopiomelanocortin-gene expression in pituitary cells.
Topics: Animals; Blotting, Northern; Brain Chemistry; Cells, Cultured; Corticosterone; Dehydroepiandrosterone; Gene Expression; Mice; Pituitary Gland; Pregnanolone; Pregnenolone; Pro-Opiomelanocortin; RNA, Messenger; Steroids | 1993 |
Isolation of two distinct 3-hydroxysteroid sulfotransferases from the guinea pig adrenal. Evidence for 3 alpha-hydroxy versus 3 beta-hydroxy stereospecificity.
Topics: Adrenal Glands; Androsterone; Animals; Blotting, Western; Chromatography, Affinity; Dehydroepiandrosterone; Guinea Pigs; Isoelectric Point; Kinetics; Male; Peptide Mapping; Pregnanolone; Stereoisomerism; Substrate Specificity; Sulfotransferases; Sulfurtransferases | 1993 |
Neurosteroids in the mouse brain: behavioral and pharmacological effects of a 3 beta-hydroxysteroid dehydrogenase inhibitor.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Brain; Dehydroepiandrosterone; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Mice; Pregnanolone; Pregnenolone; Progesterone; Sexual Behavior, Animal | 1996 |
Chronic neurosteroid treatment prevents the development of morphine tolerance and attenuates abstinence behavior in mice.
Topics: Analgesics, Opioid; Animals; Dehydroepiandrosterone; Drug Tolerance; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pregnanolone; Pregnenolone; Reaction Time; Steroids; Substance Withdrawal Syndrome | 1997 |
Neurosteroids may differentially affect the function of two native GABA(A) receptor subtypes in the rat brain.
Topics: Animals; Aspartic Acid; Brain; Cerebellum; Dehydroepiandrosterone; GABA Modulators; Hippocampus; Male; Norepinephrine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1998 |
Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aged; Aging; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Humans; Luteal Phase; Male; Menopause; Menstruation; Middle Aged; Ovary; Pregnanolone; Progesterone; Sex Characteristics | 1998 |
Sex and estrous cycle-dependent changes in neurosteroid and benzodiazepine effects on food consumption and plus-maze learning behaviors in rats.
Topics: Analysis of Variance; Animals; Dehydroepiandrosterone; Eating; Estrus; Female; GABA Modulators; Male; Maze Learning; Memory; Pregnanolone; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Sex Factors; Triazolam | 1999 |
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.
Topics: 5-alpha-Dihydroprogesterone; Adrenal Cortex; Animals; Brain; Brain Chemistry; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Demyelinating Diseases; Diazepam Binding Inhibitor; Immunohistochemistry; Leydig Cells; Male; Mice; Mice, Inbred Strains; Mice, Jimpy; Mice, Neurologic Mutants; Neuropeptides; Organ Specificity; Peptide Fragments; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Up-Regulation | 2000 |
Allopregnanolone and dehydroepiandrosterone response to corticotropin-releasing factor in patients suffering from Alzheimer's disease and vascular dementia.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Area Under Curve; Case-Control Studies; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dementia, Vascular; Female; GABA Modulators; Humans; Hydrocortisone; Male; Middle Aged; Pregnanolone | 2000 |
Neuropeptides, neurotransmitters, neurosteroids, and the onset of puberty.
Topics: Animals; Catecholamines; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Female; Galanin; Gonadotropin-Releasing Hormone; Humans; Melatonin; Neuropeptide Y; Neuropeptides; Neurotransmitter Agents; Opioid Peptides; Pregnanolone; Puberty; Serotonin | 2000 |
Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia.
Topics: Animals; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Embryo, Mammalian; Estradiol; Gestational Age; Microtubule-Associated Proteins; Neurons; Pregnanolone; Rats; Rats, Sprague-Dawley | 2000 |
Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.
Topics: Animals; Anxiety; Brain; Cerebral Cortex; Conflict, Psychological; Corticosterone; Dehydroepiandrosterone; Desoxycorticosterone; Electroshock; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Oocytes; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Social Isolation; Steroids; Synaptosomes; Time Factors; Xenopus laevis | 2000 |
Quantification of neurosteroids in rat plasma and brain following swim stress and allopregnanolone administration using negative chemical ionization gas chromatography/mass spectrometry.
Topics: Animals; Brain Chemistry; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Injections, Subcutaneous; Male; Pregnanes; Pregnanolone; Rats; Rats, Wistar; Reproducibility of Results; Stress, Physiological; Swimming; Testosterone | 2000 |
Neuroactive steroid levels in patients with generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Dehydroepiandrosterone; Female; gamma-Aminobutyric Acid; Humans; Male; Pregnanolone; Pregnenolone; Receptors, GABA-A | 2001 |
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Homocysteine; Humans; Hypothyroidism; Male; Microsomes; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Thyrotropin; Thyroxine; Time Factors; Triiodothyronine | 2001 |
Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.
Topics: 17-alpha-Hydroxypregnenolone; Adolescent; Adult; Blood Glucose; Body Constitution; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Homocysteine; Humans; Hydrocortisone; Hypoglycemic Agents; Insulin; Metformin; Polycystic Ovary Syndrome; Pregnanolone; Steroids | 2002 |
Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia.
Topics: Adult; Arousal; Dehydroepiandrosterone; Humans; Male; Middle Aged; Phobic Disorders; Pilot Projects; Pregnanolone; Pregnenolone; Reference Values | 2002 |
Pharmacological characterisation of cortical gamma-aminobutyric acid type A (GABAA) receptors in two Wistar rat lines selectively bred for high and low anxiety-related behaviour.
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding, Competitive; Cerebral Cortex; Dehydroepiandrosterone; Disease Models, Animal; Female; Maze Learning; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Severity of Illness Index; Swimming | 2000 |
Serum allopregnanolone levels relate to FSFI score during the menstrual cycle.
Topics: Adult; Arousal; Dehydroepiandrosterone; Female; Humans; Libido; Menstrual Cycle; Middle Aged; Pregnanolone; Testosterone | 2003 |
Adrenal function under long-term raloxifene administration.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; beta-Endorphin; Body Mass Index; Corticotropin-Releasing Hormone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Estrone; Female; Glucocorticoids; Humans; Hydrocortisone; Hypothalamus; Middle Aged; Pituitary Gland; Postmenopause; Pregnanolone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators | 2003 |
Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroids.
Topics: Adolescent; Adult; Body Mass Index; Case-Control Studies; Cognition; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Feeding and Eating Disorders; Female; Humans; Hydrocortisone; Learning; Neuropsychological Tests; Pregnanolone; Regression Analysis; Steroids | 2003 |
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Catalysis; Dehydroepiandrosterone; Female; Humans; Kinetics; Leydig Cells; Male; Microsomes; Multienzyme Complexes; Pregnancy; Pregnanolone; Pregnenolone; Progesterone; Progesterone Reductase; Steroid 17-alpha-Hydroxylase; Steroid Isomerases; Steroids; Testis | 2003 |
Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects.
Topics: Adult; Bulimia; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Multivariate Analysis; Obesity; Pregnanolone | 2003 |
Synthesis of [19- 2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates.
Topics: Androstanes; Combinatorial Chemistry Techniques; Dehydroepiandrosterone; Deuterium; Molecular Structure; Pregnanolone; Pregnenolone | 2004 |
Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins.
Topics: Adrenal Medulla; Animals; Apoptosis; bcl-X Protein; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Estrogens; Isoenzymes; NF-kappa B; PC12 Cells; Phosphorylation; Pregnanolone; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, sigma; Sigma-1 Receptor | 2004 |
Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome.
Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Androstenedione; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Estradiol; Female; Follicular Phase; Humans; Hydrocortisone; Luteal Phase; Pregnanolone; Pregnenolone; Premenstrual Syndrome; Progesterone; Testosterone | 2004 |
Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin.
Topics: Adjuvants, Immunologic; Adrenal Glands; Animals; beta-Endorphin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Hippocampus; Hypothalamo-Hypophyseal System; Hypothalamus; Ovariectomy; Pituitary Gland, Anterior; Pituitary-Adrenal System; Pregnanolone; Rats; Rats, Wistar | 2005 |
Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization.
Topics: Actins; Animals; Catecholamines; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; DNA Primers; Enzyme Induction; Nicotine; PC12 Cells; Pregnanolone; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine 3-Monooxygenase; Zona Reticularis | 2005 |
Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction.
Topics: Alcoholism; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Progesterone; Radioimmunoassay; Stereoisomerism; Steroids; Time Factors | 2005 |
Plasma concentrations of anxiolytic neuroactive steroids in men with panic disorder.
Topics: Adolescent; Adult; Anxiety; Dehydroepiandrosterone; Desoxycorticosterone; Diagnostic and Statistical Manual of Mental Disorders; Humans; Male; Panic Disorder; Pregnanolone; Progesterone; Steroids; Surveys and Questionnaires | 2005 |
Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels.
Topics: Administration, Cutaneous; Adrenal Glands; Aging; Dehydroepiandrosterone; Estradiol; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Female; Humans; Hydrocortisone; Hysterectomy; Medroxyprogesterone Acetate; Middle Aged; Norethindrone; Norethindrone Acetate; Norpregnenes; Ovariectomy; Postmenopause; Pregnanolone; Progesterone; Progestins | 2005 |
Neuroactive steroids and ethanol.
Topics: Alcoholism; Animals; Brain; Dehydroepiandrosterone; Female; Fetal Alcohol Spectrum Disorders; Humans; Male; Menstrual Cycle; Mice; Mice, Inbred C57BL; Pregnancy; Pregnanolone; Receptors, GABA-A | 2005 |
Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Dehydroepiandrosterone; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Ethylenediamines; Ligands; Male; Memory; Mice; Pregnanolone; Reaction Time; Receptors, sigma; Retention, Psychology; Steroids | 2006 |
Circulating neuroactive C21- and C19-steroids in young men before and after ejaculation.
Topics: 17-alpha-Hydroxypregnenolone; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Ejaculation; Gas Chromatography-Mass Spectrometry; Humans; Male; Orgasm; Pregnanolone; Testosterone | 2006 |
Anti-apoptotic effects of allopregnanolone on P19 neurons.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Bicuculline; Blotting, Northern; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytochromes c; Cytosol; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Interactions; Fluorescent Antibody Technique; GABA Antagonists; Mice; Mitochondria; N-Methylaspartate; Neurons; Pregnanolone; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synaptophysin; Time Factors; Tubulin | 2006 |
[Effects of morphine dependence on the levels of neurosteroids in rat brain].
Topics: Amygdala; Animals; Brain; Conditioning, Operant; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hypothalamus; Male; Morphine Dependence; Nucleus Accumbens; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley | 2005 |
Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age.
Topics: Adult; Aging; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Isomerism; Luteal Phase; Pregnanolone; Pregnenolone; Progesterone; Receptors, GABA-A | 2006 |
Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder.
Topics: 5-alpha-Dihydroprogesterone; Adult; Affect; Analysis of Variance; Dehydroepiandrosterone; Female; Humans; Menstrual Cycle; Pregnanolone; Progesterone; Receptors, GABA-A; Reference Values; Stress Disorders, Post-Traumatic | 2006 |
The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Biomarkers; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Disease Progression; Gas Chromatography-Mass Spectrometry; Humans; Male; Prefrontal Cortex; Pregnanolone; Pregnenolone | 2006 |
Neuroprotective effects of steroid analogues on P19-N neurons.
Topics: Animals; Apoptosis; Cells, Cultured; Dehydroepiandrosterone; Gene Expression Regulation; Mice; Molecular Structure; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Pregnanolone; Proto-Oncogene Proteins c-akt; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Steroids | 2007 |
Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia.
Topics: Animals; Animals, Genetically Modified; Cricetinae; Dehydroepiandrosterone; Desoxycorticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Mesocricetus; Pregnanolone; Pregnenolone | 2007 |
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids | 2008 |
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Topics: Adult; Anticonvulsants; Body Mass Index; Dehydroepiandrosterone; Desoxycorticosterone; Electroencephalography; Epilepsy; Estradiol; Female; Humans; Hydrocortisone; Pregnanolone; Pregnenolone; Premenopause; Premenstrual Syndrome; Progesterone; Receptors, GABA | 2008 |
Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cerebral Cortex; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Excitatory Amino Acids; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phosphoinositide-3 Kinase Inhibitors; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Staurosporine; Steroids | 2008 |
Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.
Topics: Age Factors; Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; Male; Pregnanolone; Rats; Rats, Long-Evans; Sodium Chloride | 2009 |
Discriminative stimulus effects of ethanol, pregnanolone, and dehydroepiandrosterone (DHEA) in rats administered ethanol or saline as adolescents.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Animals; Dehydroepiandrosterone; Discrimination, Psychological; Ethanol; Humans; Male; Models, Animal; Pregnanolone; Psychology, Adolescent; Rats; Rats, Long-Evans | 2009 |
Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001.
Topics: Adult; Afghanistan; Brain Injuries; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Male; Military Personnel; Neurotransmitter Agents; Pain; Pain Measurement; Pregnanolone; Smoking; United States; Veterans | 2010 |
Effects of positive and negative modulators of the γ-aminobutyric acid A receptor complex on responding under a differential-reinforcement-of-low-rate schedule of reinforcement in rats.
Topics: Adjuvants, Immunologic; Analysis of Variance; Anesthetics; Animals; Carbolines; Conditioning, Operant; Dehydroepiandrosterone; Dose-Response Relationship, Drug; GABA Agents; gamma-Aminobutyric Acid; Male; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement Schedule | 2010 |
Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration.
Topics: Allosteric Regulation; Animals; Brain; Dehydroepiandrosterone; Male; Morphine; Neurotransmitter Agents; Opioid-Related Disorders; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2010 |
Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour.
Topics: Androsterone; Antineoplastic Agents, Hormonal; Child; Dehydroepiandrosterone; Etiocholanolone; Humans; Leuprolide; Leydig Cell Tumor; Male; Metabolome; Pregnanolone; Puberty, Precocious; Testicular Neoplasms; Testosterone | 2011 |
Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo.
Topics: Animals; Cerebellum; Cyclic GMP; Dehydroepiandrosterone; gamma-Aminobutyric Acid; Glutamic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Nitric Oxide; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2011 |
[Correlation between neurotransmitters and neurosteroids and premenstrual syndrome patients of Gan-yang ascending syndrome and Gan-qi stagnation syndrome].
Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Estradiol; Female; Follicular Phase; Humans; Luteal Phase; Medicine, Chinese Traditional; Middle Aged; Neurotransmitter Agents; Pregnanolone; Pregnenolone; Premenstrual Syndrome; Progesterone; Young Adult | 2012 |
Effect of DHEA therapy on sexual behavior in female rats.
Topics: Adrenal Glands; Animals; beta-Endorphin; Brain; Dehydroepiandrosterone; Estradiol; Estrogens; Female; Gonadal Steroid Hormones; Ovariectomy; Pregnanolone; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal | 2013 |
Simultaneous determination of pregnenolone sulphate, dehydroepiandrosterone and allopregnanolone in rat brain areas by liquid chromatography-electrospray tandem mass spectrometry.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Hippocampus; Male; Pregnanolone; Pregnenolone; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Differential responses of two related neurosteroids to methylphenidate based on ADHD subtype and the presence of depressive symptomatology.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Biomarkers; Central Nervous System Stimulants; Child; Child, Preschool; Dehydroepiandrosterone; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Male; Methylphenidate; Neurotransmitter Agents; Pregnanolone | 2014 |
Involvement of pregnane xenobiotic receptor in mating-induced allopregnanolone formation in the midbrain and hippocampus and brain-derived neurotrophic factor in the hippocampus among female rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Dehydroepiandrosterone; Estrous Cycle; Female; Hippocampus; Mesencephalon; Oligonucleotides, Antisense; Pregnane X Receptor; Pregnanolone; Progesterone; Rats; Rats, Long-Evans; Receptors, Steroid; Sexual Behavior, Animal; Ventral Tegmental Area | 2014 |
The correlation between neurosteroids and neurotransmitters with liver yang rising and liver qi stagnation types of premenstrual syndrome.
Topics: Adult; Dehydroepiandrosterone; Dopamine; Female; gamma-Aminobutyric Acid; Humans; Liver; Medicine, Chinese Traditional; Middle Aged; Neurotransmitter Agents; Pregnanolone; Premenstrual Syndrome; Progesterone; Qi; Serotonin; Testosterone; Yin-Yang; Young Adult | 2014 |
Improvement of neuronal bioenergetics by neurosteroids: implications for age-related neurodegenerative disorders.
Topics: Adenosine Triphosphate; Aging; Androstane-3,17-diol; Animals; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Energy Metabolism; Estradiol; Estrone; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurodegenerative Diseases; Neurons; Neurotransmitter Agents; Oxygen Consumption; Pregnanolone; Progesterone; Reactive Oxygen Species; Superoxide Dismutase; Testosterone | 2014 |
Exploratory investigation of biomarker candidates for suicide in schizophrenia and bipolar disorder.
Topics: Adult; Aged; Autopsy; Biomarkers; Bipolar Disorder; Brain; Case-Control Studies; Chromatography, High Pressure Liquid; Dehydroepiandrosterone; Female; Gas Chromatography-Mass Spectrometry; Gyrus Cinguli; Humans; Male; Middle Aged; Parietal Lobe; Pilot Projects; Pregnanolone; Pregnenolone; Schizophrenia; Suicide; Young Adult | 2015 |
Comparison of dehydroepiandrosterone (DHEA) and pregnanolone with existing pharmacotherapies for alcohol abuse on ethanol- and food-maintained responding in male rats.
Topics: Acamprosate; Alcohol Drinking; Alcoholism; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Eating; Ethanol; Male; Naltrexone; Pregnanolone; Rats; Rats, Long-Evans; Self Administration; Taurine | 2015 |
The non-benzodiazepine anxiolytic drug etifoxine causes a rapid, receptor-independent stimulation of neurosteroid biosynthesis.
Topics: 17-alpha-Hydroxypregnenolone; 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Bicuculline; Complex Mixtures; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Gene Expression; Hypothalamus; Isoquinolines; Male; Neuropeptides; Oxazines; Peptide Fragments; Pregnanolone; Progesterone; Rana esculenta; Receptors, GABA-A; Tissue Culture Techniques | 2015 |
Assessment of neuroactive steroids in cerebrospinal fluid comparing acute relapse and stable disease in relapsing-remitting multiple sclerosis.
Topics: Adult; Biomarkers; Brain; Dehydroepiandrosterone; Female; Humans; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Pregnanolone; Pregnenolone; Recurrence | 2016 |
The role of steroids in the prediction of affective disorders in adult men.
Topics: Adult; Anxiety; Dehydroepiandrosterone; Depression; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Mood Disorders; Multivariate Analysis; Pregnanolone; Radioimmunoassay; Steroids; Young Adult | 2017 |
Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Biomarkers, Pharmacological; Case-Control Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hydrocortisone; Male; Metabolic Networks and Pathways; Pregnanolone; Pregnenolone; Progesterone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 2018 |
Effects of noncontingent ethanol, DHEA, and pregnanolone administration on ethanol self-administration in outbred female rats.
Topics: Alcohol Drinking; Animals; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Ethanol; Female; Pregnanolone; Rats; Rats, Long-Evans; Reinforcement Schedule; Self Administration; Treatment Outcome | 2019 |
Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD.
Topics: 5-alpha-Dihydroprogesterone; Adult; Cholestenone 5 alpha-Reductase; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Depressive Disorder, Major; GABAergic Neurons; Gas Chromatography-Mass Spectrometry; Humans; Hydroxysteroid Dehydrogenases; Male; Middle Aged; Neurosteroids; Pregnanolone; Progesterone; Severity of Illness Index; Stress Disorders, Post-Traumatic | 2019 |
Fetal Zone Steroids and Estrogen Show Sex Specific Effects on Oligodendrocyte Precursor Cells in Response to Oxidative Damage.
Topics: Animals; Dehydroepiandrosterone; Estradiol; Female; Humans; Infant, Newborn; Infant, Premature; Male; Mice; Minor Histocompatibility Antigens; Nuclear Pore Complex Proteins; Oligodendrocyte Precursor Cells; Oxidative Stress; Pregnanolone; Sex Characteristics | 2021 |