Page last updated: 2024-08-17

dehydroepiandrosterone and flutamide

dehydroepiandrosterone has been researched along with flutamide in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19908 (17.39)18.7374
1990's18 (39.13)18.2507
2000's13 (28.26)29.6817
2010's6 (13.04)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Bellavance, E; Luu-The, V; Poirier, D1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Kirschner, MA; Luthold, WW; Marcondes, JA; Minnani, SL; Samojlik, E; Wajchenberg, BL1
Ayub, M; Levell, MJ1
Torday, JS1
Acosta, AM; Arteaga, A; Arteaga, E; Correa, R; Fernández, C; López, X1
Belanger, A; Labrie, C; Labrie, F; Pelletier, G; Simard, J; Zhao, HF1
Gangnerau, MN; Picon, R1
Belanger, A; Bergeron, V; Dupont, A; Emond, J; Giguere, M; Labrie, F; Lacoursiere, Y; Monfette, G1
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F2
Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M1
Bégin, D; Labrie, F; Luthy, IA1
Belanger, A; Le Goff, JM1
Armanini, D; Castello, R; Fontanarosa, MC; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F1
Benz, R; Rossmanith, WG; Schenkel, B1
Demirçay, Z; Durmuşoğlu, F; Erenus, M; Gürbüz, O; Pekin, S1
Rabenbauer, B; Sir-Petermann, T; Wildt, L1
Cusan, L; Dupont, A; Gomez, JL; Labrie, F; Tremblay, RR1
Brentani, MM; Liberato, MH; Sonohara, S1
Angelini, F; Barletta, D; Gargani, M; Genazzani, AD; Genazzani, AR; Lippi, F; Luisi, M; Monzani, F; Pucci, E1
Barnes, KM; Cutler, GB; Hill, S; Jones, JV; Laue, L; Merke, DP1
Bélanger, A; Flamand, M; Labrie, C; Labrie, F1
deVere White, RW; French, FS; Gregory, CW; Gumerlock, PH; Hamil, KG; Harris, SE; Mohler, JL; Pretlow, TG; Sar, M; Sharief, Y; Tan, J; Wilson, EM; Zang, DY1
Baroncelli, GI; Battini, R; Bertelloni, S; Costa, S; Saggese, G; Sorrentino, MC1
Labrie, C; Labrie, F; Martel, C; Sourla, A1
Fournier, M; Labrie, C; Labrie, F; Li, S; Martel, C; Pelletier, G; Picard, S; Sourla, A; Stojanovic, M1
Hicok, KC; Hofbauer, LC; Khosla, S1
Labrie, C; Labrie, F; Richard, V; Sourla, A1
Shilling, AD; Williams, DE1
Barker, JL; Chang, YH; Li, Bs; Ma, W; Rubinow, DR; Zhang, L; Zhao, W1
Dvoráková, K; Hill, M; Stanická, S; Stárka, L; Vondra, K; Vrbíková, J1
Nakajima, A; Sekihara, H; Takahashi, H1
Hajszan, T; Leranth, C; MacLusky, NJ1
Dai, A; Dawood, T; Funder, JW; Komesaroff, PA; Lew, R; Ling, S; Myles, K; Sudhir, K; Williams, MR1
Jasso-Kamel, J; Montaño, LM; Navarrete, E; Perusquía, M1
Arnold, JT; Blackman, MR; Le, H; McFann, KK1
Powell, JM; Sonnenfeld, G1
Labrie, F1
Li, DJ; Wang, L; Wang, WJ; Wang, YD; Zhu, Y1
Andruszkow, H; Frink, M; Hildebrand, F; Krettek, C; Mommsen, P; Neunaber, C; Zeckey, C1
Díaz-Cedillo, F; Figueroa-Valverde, L; García-Cervera, E; López-Ramos, M; Martinez-Camacho, R; Pool Gómez, E; Rosas-Nexticapa, M1
Angele, MK; Chaudry, IH; Hubbard, WJ; Pratschke, S1
Anai, S; Fujimoto, K; Miyake, M; Nakai, Y; Tanaka, N; Tatsumi, Y1
Fan, L; Jiang, L; Jin, Y; Mo, F; Qin, A; Qin, J; Xie, W1
Enrique H, L; Gabriela A, A; Gisela S, B; Laura, K; M Virginia, A; M Virginia, T; Véronica L, B1

Reviews

3 review(s) available for dehydroepiandrosterone and flutamide

ArticleYear
[Keyrole of endocrinology in the victory against prostate cancer].
    Bulletin du cancer, 2006, Volume: 93, Issue:9

    Topics: Adrenal Glands; Androgen Antagonists; Antineoplastic Agents, Hormonal; Dehydroepiandrosterone; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatectomy; Prostatic Neoplasms

2006
Immunomodulation in polytrauma and polymicrobial sepsis - where do we stand?
    Recent patents on inflammation & allergy drug discovery, 2011, Volume: 5, Issue:1

    Topics: Androstenediol; Animals; Dehydroepiandrosterone; Finasteride; Flutamide; Humans; Immunomodulation; Lipopeptides; Multiple Trauma; Sepsis

2011
Gender differences in sepsis: cardiovascular and immunological aspects.
    Virulence, 2014, Jan-01, Volume: 5, Issue:1

    Topics: Androgen Receptor Antagonists; Androgens; Animals; Cardiovascular System; Dehydroepiandrosterone; Estrogens; Female; Flutamide; Humans; Immunity, Cellular; Male; Mesenchymal Stem Cell Transplantation; Mice; Sex Factors; Shock, Septic

2014

Trials

9 trial(s) available for dehydroepiandrosterone and flutamide

ArticleYear
Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: a marked improvement in response and survival.
    Journal of steroid biochemistry, 1985, Volume: 23, Issue:5B

    Topics: Acid Phosphatase; Anilides; Bone and Bones; Bone Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Orchiectomy; Prostatic Neoplasms; Radionuclide Imaging; Testosterone

1985
Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior.
    Fertility and sterility, 1995, Volume: 64, Issue:3

    Topics: Acne Vulgaris; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Hirsutism; Humans; Leukocytes, Mononuclear; Receptors, Androgen; Testosterone

1995
Role of androgens in the regulation of the human menstrual cycle.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1994, Volume: 8, Issue:3

    Topics: Administration, Oral; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Luteinizing Hormone; Menstrual Cycle; Progesterone; Radioimmunoassay; Receptors, Androgen; Sex Hormone-Binding Globulin; Testosterone

1994
Comparison of the efficacy of spironolactone versus flutamide in the treatment of hirsutism.
    Fertility and sterility, 1994, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Spironolactone; Testosterone

1994
Comparison of flutamide and spironolactone in the treatment of hirsutism: a randomized controlled trial.
    Fertility and sterility, 1994, Volume: 61, Issue:2

    Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Premenopause; Progesterone; Spironolactone; Testosterone

1994
A preliminary study of flutamide, testolactone, and reduced hydrocortisone dose in the treatment of congenital adrenal hyperplasia.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:10

    Topics: 17-alpha-Hydroxyprogesterone; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Bone Development; Child; Child, Preschool; Dehydroepiandrosterone; Female; Flutamide; Humans; Hydrocortisone; Infant; Male; Seasons; Testolactone; Weight Gain

1996
Androgen-receptor blockade does not impair bone mineral density in adolescent females.
    Calcified tissue international, 1997, Volume: 61, Issue:1

    Topics: Absorptiometry, Photon; Acne Vulgaris; Adolescent; Adult; Analysis of Variance; Androgen Antagonists; Androgen Receptor Antagonists; Androstane-3,17-diol; Bone Density; Dehydroepiandrosterone; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Lumbar Vertebrae; Luteinizing Hormone; Sex Hormone-Binding Globulin

1997
Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:9

    Topics: Adult; Aged; Animals; Brachial Artery; Cattle; Cell Division; Cells, Cultured; Dehydroepiandrosterone; Double-Blind Method; Endothelial Cells; Estradiol; Female; Flutamide; Fulvestrant; Humans; Middle Aged; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Receptors, Androgen; Receptors, Estrogen; Skin; Testosterone

2004
A Randomized Control Trial Comparing the Efficacy of Antiandrogen Monotherapy: Flutamide vs. Bicalutamide.
    Hormones & cancer, 2015, Volume: 6, Issue:4

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenedione; Anilides; Dehydroepiandrosterone; Flutamide; Humans; Male; Neoplasm Staging; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone; Tosyl Compounds

2015

Other Studies

34 other study(ies) available for dehydroepiandrosterone and flutamide

ArticleYear
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Treatment of hirsutism in women with flutamide.
    Fertility and sterility, 1992, Volume: 57, Issue:3

    Topics: Adult; Analysis of Variance; Androstane-3,17-diol; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome

1992
Suppression of plasma androgens by the antiandrogen flutamide in prostatic cancer patients treated with Zoladex, a GnRH analogue.
    Clinical endocrinology, 1990, Volume: 32, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androgens; Androstenedione; Anilides; Antineoplastic Agents; Buserelin; Dehydroepiandrosterone; Depression, Chemical; Flutamide; Goserelin; Humans; Hydroxyprogesterones; Male; Orchiectomy; Prostatic Neoplasms; Testosterone

1990
Androgens delay human fetal lung maturation in vitro.
    Endocrinology, 1990, Volume: 126, Issue:6

    Topics: Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Fetal Organ Maturity; Flutamide; Humans; Lung; Phosphatidylcholines; Pulmonary Surfactants

1990
[The effect of a peripheral androgenic blockade on plasma lipoproteins in hirsutism patients].
    Revista medica de Chile, 1990, Volume: 118, Issue:12

    Topics: Adult; Alanine Transaminase; Analysis of Variance; Anovulation; Dehydroepiandrosterone; Drug Evaluation; Female; Flutamide; Hirsutism; Humans; Lipoproteins; Testosterone; Time Factors

1990
Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate.
    Endocrinology, 1989, Volume: 124, Issue:6

    Topics: Adrenal Glands; Androgen-Binding Protein; Androgens; Androstenedione; Animals; Autoradiography; Carrier Proteins; Dehydroepiandrosterone; Flutamide; Genes; Intracellular Signaling Peptides and Proteins; Kinetics; Male; Orchiectomy; Prostate; Prostatein; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Secretoglobins; Sulfur Radioisotopes; Time Factors; Transcription, Genetic; Uteroglobin

1989
Onset of steroidogenesis and differentiation of functional LH receptors in rat fetal testicular cultures.
    Archives of andrology, 1987, Volume: 18, Issue:3

    Topics: Aminoglutethimide; Animals; Binding, Competitive; Bucladesine; Cyproterone; Cyproterone Acetate; Dehydroepiandrosterone; Flutamide; Gestational Age; Luteinizing Hormone; Male; Organ Culture Techniques; Progesterone; Rats; Rats, Inbred Strains; Receptors, LH; Testis; Testosterone

1987
Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:6

    Topics: Aged; Aminoglutethimide; Androstane-3,17-diol; Androstanols; Androsterone; Anilides; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms

1987
Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:5

    Topics: Anilides; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Flutamide; Gonadal Steroid Hormones; Hormones; Humans; Middle Aged; Time Factors

1988
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate

1988
Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro.
    Molecular and cellular endocrinology, 1988, Volume: 58, Issue:2-3

    Topics: Androgens; Androstenediol; Androstenediols; Androstenedione; Animals; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Growth; Male; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured

1988
Metabolism of tritiated C19 steroids by Shionogi mouse mammary tumors.
    Steroids, 1984, Volume: 44, Issue:3

    Topics: Androgens; Androstenediols; Androstenedione; Androsterone; Animals; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Flutamide; Male; Mammary Neoplasms, Experimental; Mice; Steroid Isomerases; Testosterone

1984
The effect of flutamide on pulsatile gonadotrophin secretion in hyperandrogenaemic women.
    Human reproduction (Oxford, England), 1993, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Luteinizing Hormone; Sex Hormone-Binding Globulin; Testosterone

1993
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1993, Volume: 14, Issue:1

    Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regulation; Estradiol; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Tumor Cells, Cultured

1993
Prolonged treatment of hirsutism with flutamide alone in patients affected by polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1995, Volume: 9, Issue:3

    Topics: Adult; Androgen Antagonists; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Ultrasonography

1995
High bioavailability of dehydroepiandrosterone administered percutaneously in the rat.
    The Journal of endocrinology, 1996, Volume: 150 Suppl

    Topics: Administration, Cutaneous; Administration, Oral; Androgen Antagonists; Animals; Biological Availability; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Luteinizing Hormone; Male; Organ Size; Ovariectomy; Prostate; Rats; Rats, Sprague-Dawley; Uterus

1996
Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen-dependent human prostate cancer xenograft CWR22 and LNCaP cells.
    Molecular endocrinology (Baltimore, Md.), 1997, Volume: 11, Issue:4

    Topics: Androgen Antagonists; Animals; Chromosome Mapping; Dehydroepiandrosterone; Epithelium; Estradiol; Flutamide; Haplorhini; Humans; Ligands; Male; Mutation; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Transcriptional Activation; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured

1997
Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland.
    Endocrinology, 1998, Volume: 139, Issue:2

    Topics: Androgen Antagonists; Androgens; Animals; Benzopyrans; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Flutamide; Mammary Glands, Animal; Medroxyprogesterone; Ovariectomy; Propionates; Rats; Rats, Sprague-Dawley

1998
Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat.
    The Journal of endocrinology, 1998, Volume: 157, Issue:3

    Topics: Androgen Antagonists; Animals; Benzopyrans; Bone Density; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Femur; Flutamide; Medroxyprogesterone Acetate; Ovariectomy; Progesterone Congeners; Propionates; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1998
Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line.
    Journal of cellular biochemistry, 1998, Oct-01, Volume: 71, Issue:1

    Topics: Adrenal Glands; Aged; Alkaline Phosphatase; Androgen Antagonists; Androgens; Cell Division; Cell Line; Collagen; Dehydroepiandrosterone; Dihydrotestosterone; DNA-Binding Proteins; Early Growth Response Transcription Factors; Flutamide; Gene Expression Regulation; Humans; Kruppel-Like Transcription Factors; Male; Osteoblasts; Osteocalcin; Testosterone; Transcription Factors; Transforming Growth Factor beta

1998
Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin.
    The Journal of endocrinology, 2000, Volume: 166, Issue:2

    Topics: Administration, Cutaneous; Androgen Antagonists; Animals; Benzopyrans; Dehydroepiandrosterone; Estrogen Receptor Modulators; Female; Flutamide; Hyperplasia; Models, Animal; Ovariectomy; Propionates; Random Allocation; Rats; Rats, Sprague-Dawley; Sebaceous Glands; Stimulation, Chemical; Time Factors

2000
The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.
    The Journal of steroid biochemistry and molecular biology, 2000, Nov-15, Volume: 74, Issue:4

    Topics: Androgen Antagonists; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Flutamide; Liver; Male; Microsomes, Liver; Oncorhynchus mykiss; Receptors, Androgen; Sex Factors; Vitellogenins

2000
Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways.
    Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2

    Topics: Androgen Antagonists; Animals; Apoptosis; Chromones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fetal Proteins; Flutamide; Morpholines; Nerve Tissue Proteins; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen; Telencephalon

2002
Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome.
    Gynecologic and obstetric investigation, 2004, Volume: 58, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgen Antagonists; Androgens; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipids; Obesity; Polycystic Ovary Syndrome; Steroids; Testosterone

2004
Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:3

    Topics: Adult; Apoptosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flow Cytometry; Flutamide; Humans; Lymphocytes; Male; Middle Aged; Staurosporine; Tamoxifen

2004
Effects of dehydroepiandrosterone and flutamide on hippocampal CA1 spine synapse density in male and female rats: implications for the role of androgens in maintenance of hippocampal structure.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Adjuvants, Immunologic; Androgen Antagonists; Androgens; Animals; Aromatase; Aromatase Inhibitors; Dehydroepiandrosterone; Female; Flutamide; Hippocampus; Male; Microscopy, Electron; Orchiectomy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synapses

2004
Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels.
    Biology of reproduction, 2005, Volume: 73, Issue:2

    Topics: Androgen Antagonists; Androgens; Androstenediol; Androsterone; Calcium Channels, L-Type; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Myometrium; Pregnancy; Protein Synthesis Inhibitors; Statistics, Nonparametric; Testosterone; Uterine Contraction

2005
DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:5

    Topics: Androgen Antagonists; Anilides; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Middle Aged; Nitriles; Prostate; Receptor, IGF Type 1; Stromal Cells; Testosterone; Tosyl Compounds

2006
The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2006, Volume: 26, Issue:1

    Topics: Adjuvants, Immunologic; Androgen Antagonists; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Cytokines; Dehydroepiandrosterone; Dimethyl Sulfoxide; Female; Flutamide; Mice; Solvents; Spleen

2006
Dehydroepiandrosterone improves murine osteoblast growth and bone tissue morphometry via mitogen-activated protein kinase signaling pathway independent of either androgen receptor or estrogen receptor.
    Journal of molecular endocrinology, 2007, Volume: 38, Issue:4

    Topics: Androgen Receptor Antagonists; Animals; Apoptosis; Bone and Bones; Bone Density Conservation Agents; Butadienes; Cell Cycle; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Flutamide; Fulvestrant; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Nitriles; Osteoblasts; Ovariectomy; Phosphorylation; Proliferating Cell Nuclear Antigen; Receptors, Androgen; Receptors, Estrogen

2007
Positive inotropic activity induced by a dehydroisoandrosterone derivative in isolated rat heart model.
    Archives of pharmacal research, 2013, Volume: 36, Issue:10

    Topics: Androgen Antagonists; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiotonic Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Flutamide; In Vitro Techniques; Male; Metoprolol; Models, Animal; Nifedipine; Prazosin; Rats; Ventricular Function, Left

2013
DHEA improves the antioxidant capacity of endometrial stromal cells and improves endometrium receptivity via androgen receptor.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 198

    Topics: Animals; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Endometrium; Female; Flutamide; Homeobox A10 Proteins; Homeodomain Proteins; Immunohistochemistry; Mice; Reactive Oxygen Species; Receptors, Androgen; Stromal Cells

2016
Androgen receptor and uterine histoarchitecture in a PCOS rat model.
    Molecular and cellular endocrinology, 2020, 12-01, Volume: 518

    Topics: Animals; Animals, Newborn; Aquaporins; Collagen; Dehydroepiandrosterone; Disease Models, Animal; Estrogen Receptor alpha; Female; Flutamide; Gene Expression Regulation; Humans; Polycystic Ovary Syndrome; Rats; Receptors, Androgen; Testosterone; Uterus

2020