Page last updated: 2024-08-17

dehydroepiandrosterone and epiandrosterone

dehydroepiandrosterone has been researched along with epiandrosterone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Auwerx, J; Gioiello, A; Hofmann, AF; Macchiarulo, A; Pellicciari, R; Saladin, R; Sato, H; Schoonjans, K; Thomas, C; Une, M1
Cordeiro, AT; Michels, PA; Thiemann, OH1
Bellavance, E; Luu-The, V; Poirier, D1
Cordeiro, AT; Thiemann, OH1
Dawson, M; Fairweather, EE; Hamilton, NM; Hamilton, NS; Hitchin, JR; James, DI; Jones, SD; Jordan, AM; Lyons, AJ; Ogilvie, DJ; Small, HF; Thomson, GJ; Waddell, ID1
Chen, H; Cui, HW; Gao, W; Gu, XZ; He, Y; Liu, MY; Lv, F; Peng, S; Qiu, WW; Wang, JH; Wang, Y; Xie, J; Yi, Z1
Garcia, AA; Koperniku, A; Mochly-Rosen, D1

Reviews

2 review(s) available for dehydroepiandrosterone and epiandrosterone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
    Journal of medicinal chemistry, 2022, 03-24, Volume: 65, Issue:6

    Topics: Communicable Diseases; Drug Discovery; Glucosephosphate Dehydrogenase; High-Throughput Screening Assays; Humans; Inflammation; Neoplasms

2022

Other Studies

6 other study(ies) available for dehydroepiandrosterone and epiandrosterone

ArticleYear
Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Bile Acids and Salts; CHO Cells; Cricetinae; Cricetulus; Drug Design; Drug Evaluation, Preclinical; Hormones; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptors, G-Protein-Coupled; Stereoisomerism; Structure-Activity Relationship

2008
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.
    Bioorganic & medicinal chemistry, 2009, Mar-15, Volume: 17, Issue:6

    Topics: Animals; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; RNA Interference; Trypanosoma brucei brucei

2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
16-bromoepiandrosterone, an activator of the mammalian immune system, inhibits glucose 6-phosphate dehydrogenase from Trypanosoma cruzi and is toxic to these parasites grown in culture.
    Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13

    Topics: Androsterone; Dehydroepiandrosterone; Glucosephosphate Dehydrogenase; Humans; Immune System; Kinetics; Recombinant Proteins; Trypanocidal Agents; Trypanosoma cruzi; Trypanosomiasis, African

2010
Novel steroid inhibitors of glucose 6-phosphate dehydrogenase.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Antineoplastic Agents; Cell Survival; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; HEK293 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pregnanes; Structure-Activity Relationship

2012
Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents.
    European journal of medicinal chemistry, 2016, Mar-23, Volume: 111

    Topics: Androstenes; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Proline; Structure-Activity Relationship

2016