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dehydroepiandrosterone and 9,10-dimethyl-1,2-benzanthracene

dehydroepiandrosterone has been researched along with 9,10-dimethyl-1,2-benzanthracene in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199011 (50.00)18.7374
1990's9 (40.91)18.2507
2000's2 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perantoni, A; Schwartz, AG1
Liem, A; Miller, EC; Miller, JA; Surh, YJ1
Hart, RW; Magee, PN; Prasanna, HR1
Fairman, DK; Lewbart, ML; Pashko, LL; Polansky, M; Schwartz, AG1
Labrie, F; Marchetti, B; Spinola, PG1
Lewbart, ML; Pashko, LL; Schwartz, AG1
Nishino, H1
Hard, GC; Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR1
Pashko, LL; Schwartz, AG2
Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR1
Adams, JB; Chandra, DP; Foo, T; Li, K; Pewnim, T1
Schwartz, AG; Tannen, RH1
Bélanger, A; Labrie, F; Li, S; Yan, X1
Inoue, M; Kohama, T; Suzuki, N; Terada, S1
Bélanger, A; Labrie, C; Labrie, F; Luo, S1
Bélanger, A; Labrie, C; Labrie, F; Luo, S; Sourla, A1
Ikegwuonu, FI; Jefcoate, CR1
Han, HM; Jung, KK; Kang, SY; Kim, SH; Kim, TG; Lee, YK; Oh, HY; Rheu, HM1
Ciolino, HP; Yeh, GC1
Cao, Y; Fu, Z; Han, R; Wang, F; Yang, S1
Ciolino, HP; MacDonald, CJ; Yeh, GC1

Trials

1 trial(s) available for dehydroepiandrosterone and 9,10-dimethyl-1,2-benzanthracene

ArticleYear
Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Calcium; Carcinogens; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Femur; Lipids; Lumbar Vertebrae; Mammary Neoplasms, Experimental; Phosphorus; Rats; Rats, Sprague-Dawley; Testosterone; Triglycerides

1997

Other Studies

21 other study(ies) available for dehydroepiandrosterone and 9,10-dimethyl-1,2-benzanthracene

ArticleYear
Protective effect of dehydroepiandrosterone against aflatoxin B1-and 7,12-dimethylbenz(a)anthracene-induced cytotoxicity and transformation in cultured cells.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Benz(a)Anthracenes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dehydroepiandrosterone; Epithelial Cells; Epithelium; Etiocholanolone; Liver; Male; Rats; Testosterone; Thymidine; Time Factors

1975
Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Biotransformation; Castration; Dehydroepiandrosterone; Estradiol; Female; Liver; Male; Pentachlorophenol; Rats; Rats, Inbred Strains; Sex Factors; Sulfotransferases; Sulfurtransferases; Testosterone

1991
Effect of dehydroepiandrosterone (DHEA) on the metabolism of 7,12-dimethylbenz[a]anthracene (DMBA) in rats.
    Carcinogenesis, 1989, Volume: 10, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytosol; Dehydroepiandrosterone; DNA; Glutathione Transferase; Liver; Male; Microsomes, Liver; Proteins; Rats; Rats, Inbred Strains; Reference Values; Tritium

1989
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs.
    Carcinogenesis, 1989, Volume: 10, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dehydroepiandrosterone; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1989
Adrenal steroids stimulate growth and progesterone receptor levels in rat uterus and DMBA-induced mammary tumors.
    Breast cancer research and treatment, 1986, Volume: 8, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Androstenediol; Androstenedione; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Mammary Neoplasms, Experimental; Ovariectomy; Promegestone; Rats; Rats, Inbred Strains; Receptors, Progesterone; Uterus

1986
Novel dehydroepiandrosterone analogues with enhanced biological activity and reduced side effects in mice and rats.
    Cancer research, 1988, Sep-01, Volume: 48, Issue:17

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dehydroepiandrosterone; DNA; Eating; Female; Glucosephosphate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Rats; Structure-Activity Relationship

1988
[Mechanism of tumor promotion].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1988, Volume: 182, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calmodulin; Carcinogens; Dehydroepiandrosterone; Female; Flunarizine; Mice; Neoplasms, Experimental; Skin Neoplasms

1988
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin papillomas and carcinomas by dehydroepiandrosterone and 3-beta-methylandrost-5-en-17-one in mice.
    Cancer research, 1985, Volume: 45, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Androstenes; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Female; Mice; Papilloma; Skin Neoplasms

1985
Effect of food restriction, dehydroepiandrosterone, or obesity on the binding of 3H-7,12-dimethylbenz(a)anthracene to mouse skin DNA.
    Journal of gerontology, 1983, Volume: 38, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; DNA; Food Deprivation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Skin

1983
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenes; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; Drug Administration Schedule; Drug Antagonism; Estradiol; Female; Mice; Papilloma; Phorbols; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterus

1984
Effect of hormone manipulation on oxidation, reduction and sulphurylation of dehydroepiandrosterone and oestrone in DMBA-induced rat mammary tumours.
    British journal of cancer, 1980, Volume: 41, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine Nucleotides; Animals; Castration; Dehydroepiandrosterone; Estradiol; Estrone; Female; Mammary Neoplasms, Experimental; Oxidation-Reduction; Progesterone; Rats; Sulfates

1980
Inhibition of 7,12-dimethylbenz[a]anthracene- and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone.
    Carcinogenesis, 1981, Volume: 2, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Dehydroepiandrosterone; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Urethane

1981
Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(a)anthracene (DMBA) in the rat.
    Breast cancer research and treatment, 1994, Volume: 29, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Drug Implants; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Prolactin; Rats; Rats, Sprague-Dawley; Time Factors

1994
Inhibition of 7,12-dimethylbenz[a]anthracene-induced lung tumorigenesis in A/J mice by food restriction is reversed by adrenalectomy.
    Carcinogenesis, 1996, Volume: 17, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Carcinogens; Corticosterone; Dehydroepiandrosterone; Fasting; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental

1996
Effects of dehydroepiandrosterone and other sex steroid hormones on mammary carcinogenesis by direct injection of 7,12-dimethylbenz(a) anthracene (DMBA) in hyperprolactinemic female rats.
    Breast cancer research and treatment, 1997, Volume: 43, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Cocarcinogenesis; Dehydroepiandrosterone; Drug Interactions; Estradiol; Female; Gonadal Steroid Hormones; Hyperprolactinemia; Mammary Neoplasms, Experimental; Pimozide; Progesterone; Rats; Rats, Wistar; Testosterone

1997
Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(A)anthracene-induced mammary carcinoma in the rat.
    Endocrinology, 1997, Volume: 138, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Benzopyrans; Bone Density; Calcium; Carcinogens; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Female; Genitalia, Female; Lipids; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Phosphorus; Prolactin; Propionates; Random Allocation; Rats; Rats, Sprague-Dawley

1997
Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1)
    Molecular and cellular biochemistry, 1999, Volume: 198, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyl-CoA Oxidase; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Cytosol; Dehydroepiandrosterone; Embryo, Mammalian; Enzyme Induction; Fatty Acids; Fibroblasts; Gene Expression Regulation, Enzymologic; Mice; Oxidation-Reduction; Oxidoreductases; Peroxisomes; Polychlorinated Dibenzodioxins; Signal Transduction

1999
Modulation of chemical carcinogen-induced unscheduled DNA synthesis by dehydroepiandrosterone (DHEA) in the primary rat hepatocytes.
    Archives of pharmacal research, 1999, Volume: 22, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Dehydroepiandrosterone; DNA; Ethyl Methanesulfonate; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methyl Methanesulfonate; Rats; Rats, Sprague-Dawley

1999
The steroid hormone dehydroepiandrosterone inhibits CYP1A1 expression in vitro by a post-transcriptional mechanism.
    The Journal of biological chemistry, 1999, Dec-03, Volume: 274, Issue:49

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Carcinogens; Cytochrome P-450 CYP1A1; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Humans; Neoplasms; Polychlorinated Dibenzodioxins; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger; Time Factors; Transfection; Tumor Cells, Cultured

1999
[Anti-mutagenicity activity of dehydroepiandrosterone].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2002, Volume: 24, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Antimutagenic Agents; Dehydroepiandrosterone; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Glucosephosphate Dehydrogenase; Mammary Neoplasms, Experimental; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Salmonella; Time Factors; Tumor Cells, Cultured

2002
Inhibition of carcinogen-activating enzymes by 16alpha-fluoro-5-androsten-17-one.
    Cancer research, 2002, Jul-01, Volume: 62, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Biotransformation; Breast Neoplasms; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Drug Interactions; Enzyme Inhibitors; Humans; Liver Neoplasms; Polychlorinated Dibenzodioxins; RNA, Messenger; Tumor Cells, Cultured

2002