dehydrocostus lactone has been researched along with costunolide in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (10.87) | 18.2507 |
| 2000's | 9 (19.57) | 29.6817 |
| 2010's | 28 (60.87) | 24.3611 |
| 2020's | 4 (8.70) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuda, H; Shimoda, H; Uemura, T; Yoshikawa, M | 1 |
| Don, MJ; Lee, GH; Lu, JJ; Sun, CM; Syu, WJ | 1 |
| Bachelier, A; Klein, CD; Mayer, R | 1 |
| Chen, Y; Ding, Y; Fan, H; Gao, Y; Han, B; Ji, Q; Jia, Y; Li, D; Li, LY; Li, Q; Lin, J; Long, J; Lu, Y; Ma, W; Ma, X; Qiu, C; Shi, Q; Shi, Y; Tong, Z; Yang, M; Zhai, J; Zhang, H; Zhang, J; Zhang, Q; Zhang, W | 1 |
| Da Costa, FB; Klempnauer, KH; Schmidt, TJ; Schomburg, C; Schuehly, W | 1 |
| Chen, HC; Chou, CK; Lee, SD; Wang, JC; Yeh, SF | 1 |
| Muro, MD; Olaguibel, JM; Quirce, S; Tabar, AI | 1 |
| du Peloux Menagé, H; Hawk, JL; Ross, JS; White, IR | 1 |
| Ando, M; Arao, K; Kataoka, T; Magae, J; Nagai, K; Nishimura, T; Otake, N; Suzuki, H; Taniguchi, M; Uramoto, M | 1 |
| Kagerura, T; Matsuda, H; Morikawa, T; Toguchida, I; Ueda, H; Yoshikawa, M | 1 |
| Kawahara, Y; Matsuda, H; Morikawa, T; Shimoda, H; Uemura, T; Yoshikawa, M | 1 |
| Kato, K; Kawanishi, K; Matsumoto, K; Okugawa, H; Ueda, R | 1 |
| Alanko, K; Estlander, T; Jolanki, R; Kanerva, L | 1 |
| Li, A; Liu, R; Sun, A | 1 |
| Castilho, PC; Costa, MC; González, HG; Luna-Herrera, J; Rodrigues, AI | 1 |
| Candeias, MF; Ramos, P; Tinoco, MT | 1 |
| Bi, Y; Feng, S; Hu, F; Li, W; Wang, C; Wu, Y | 1 |
| Butturini, E; Cavalieri, E; Darra, E; de Prati, AC; Mariotto, S; Murayama, N; Rigo, A; Shoji, K; Suzuki, H; Watanabe, Y; Yamazaki, H | 1 |
| Cai, D; Liu, J; Zhang, Q | 1 |
| Bao, X; Fu, C; He, Y; Hu, H; Mao, Q; Wang, Z | 1 |
| Chen, R; Ma, L; Wu, F; Zhang, T | 1 |
| He, C; Ma, G; Peng, Y; Wei, H; Xiao, P | 1 |
| Bauer, R; Boechzelt, H; Kaltenegger, H; Kretschmer, N; Kunert, O; Leithner, A; Lohberger, B; Rinner, B; Stuendl, N; Wolf, E | 1 |
| Bauer, R; Bernhart, E; Bonyadi Rad, E; Kaltenegger, H; Kretschmer, N; Leithner, A; Lohberger, B; Rinner, B; Steinecker-Frohnwieser, B; Stuendl, N; Weinberg, AM | 1 |
| Gao, W; Guo, H; Hu, X; Liu, C; Liu, Z; Qu, Z; Zhang, J | 1 |
| Ahmad, A; Butturini, E; Cuzzocrea, S; Di Paola, R; Mariotto, S; Paterniti, I; Suzuki, H | 1 |
| Gao, W; Guo, H; Liu, C; Qu, Z; Zhang, J | 1 |
| Gu, X; Guo, X; Peng, Z; Wang, Y; Yan, C | 1 |
| Albanesi, C; Butturini, E; Cavani, A; Madonna, S; Mariotto, S; Scarponi, C; Sestito, R | 1 |
| Dong, GZ; Hyeon, JS; Lee, HJ; Ryu, JH; Shim, AR | 1 |
| Jeong, SJ; Jin, SE; Kim, OS; Lim, HS; Shin, HK | 1 |
| Kurita, M; Nishimura, Y; Suzuki, T; Tabata, K; Takeda, T; Uchiyama, T | 1 |
| Lin, X; Peng, Z; Su, C | 1 |
| Chen, YL; Gao, WY; Jin, ZX; Qu, Z; Wang, L; Zhang, JZ | 1 |
| Cao, K; Qian, W; Xu, Y; Zhang, Q; Zhang, X; Zhou, Z | 1 |
| Chen, Y; Gao, W; Huang, H; Jin, Z; Man, S; Wang, L; Zhang, J; Zheng, H | 1 |
| Ashok Yadav, P; Devi, A; Jain, N; Pavan Kumar, Ch; Rao Vadaparthi, R; Shankaraiah, G; Sowjanya, P; Suresh Babu, K | 1 |
| Fan, J; Ji, W; Lin, X; Liu, C; Peng, Z; Su, C; Wang, Y; Xu, Y; Yan, C | 1 |
| Álvarez, JA; Ayuso, J; Cala, A; Fernández-Aparicio, M; Macías, FA; Molinillo, JMG; Rubiales, D | 1 |
| Hwang, J; Im, DS; Kang, S; Lee, BK; Lee, SJ; Nam, SY; Park, SJ | 1 |
| Dong, S; Jia, HM; Liu, YT; Ma, LY; Yu, CY; Yu, M; Zhang, HW; Zou, ZM | 1 |
| Jin, H; Li, X; Liu, J; Qin, B; Su, A; Xie, M; Yan, Z; Yang, X | 1 |
| Hu, H; Li, Q; Wang, Z; Xie, Y | 1 |
| Fujita, H; Ohta, T; Okubo, S; Shoyama, Y; Uto, T | 1 |
| Chen, M; Liao, Z; Meng, F; Tao, Y; Wang, G; Wei, X; Zong, W | 1 |
| Bai, Q; Huang, H; Huang, Z; Su, J; Wei, S; Wu, W; Yun, X; Zhang, C; Zhang, Y | 1 |
2 review(s) available for dehydrocostus lactone and costunolide
| Article | Year |
|---|---|
Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Drug Resistance, Multiple; Humans; Lactones; Sesquiterpenes | 2015 |
Antitumor activity and mechanism of costunolide and dehydrocostus lactone: Two natural sesquiterpene lactones from the Asteraceae family.
Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Cell Line, Tumor; Humans; Lactones; Sesquiterpenes | 2020 |
44 other study(ies) available for dehydrocostus lactone and costunolide
| Article | Year |
|---|---|
Preventive effect of sesquiterpenes from bay leaf on blood ethanol elevation in ethanol-loaded rat: structure requirement and suppression of gastric emptying.
Topics: Animals; Ethanol; Gastric Emptying; Male; Molecular Structure; Plant Leaves; Rats; Rats, Wistar; Sesquiterpenes | 1999 |
Cytotoxic sesquiterpene lactones from the root of Saussurea lappa.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; HeLa Cells; Humans; Lactones; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plant Roots; Plants, Medicinal; Saussurea; Sesquiterpenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.
Topics: Alkyl and Aryl Transferases; Enzyme Inhibitors; Escherichia coli; Lactones; Peptidoglycan; Pseudomonas aeruginosa; Sesquiterpenes; Structure-Activity Relationship | 2006 |
Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Lactones; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Prodrugs; Sesquiterpenes; Sesquiterpenes, Guaiane; Structure-Activity Relationship; Transplantation, Heterologous | 2012 |
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships.
Topics: Acetyltransferases; Animals; Cell Line; Cell Survival; Chickens; Computer Simulation; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Sesquiterpenes; Structure-Activity Relationship | 2013 |
Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Drugs, Chinese Herbal; Gene Expression Regulation, Viral; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Humans; Lactones; Molecular Structure; Plant Roots; RNA, Messenger; RNA, Viral; Sesquiterpenes; Tumor Cells, Cultured | 1995 |
Airborne contact dermatitis from Frullania.
Topics: Adult; Aged; Aged, 80 and over; Benzoquinones; Dermatitis, Allergic Contact; Diagnosis, Differential; Female; Humans; Lactones; Male; Middle Aged; Patch Tests; Photosensitivity Disorders; Plants; Sesquiterpenes; Sesquiterpenes, Eudesmane | 1994 |
Sesquiterpene lactone contact sensitivity: clinical patterns of Compositae dermatitis and relationship to chronic actinic dermatitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Dermatitis, Allergic Contact; Female; Humans; Lactones; Male; Middle Aged; Photosensitivity Disorders; Plants; Sesquiterpenes; Sesquiterpenes, Eudesmane | 1993 |
Costunolide and dehydrocostus lactone as inhibitors of killing function of cytotoxic T lymphocytes.
Topics: 4-Butyrolactone; Cytotoxicity, Immunologic; Lactones; Phosphorylation; Sesquiterpenes; T-Lymphocytes, Cytotoxic; Tyrosine | 1995 |
Inhibitory effects of sesquiterpenes from bay leaf on nitric oxide production in lipopolysaccharide-activated macrophages: structure requirement and role of heat shock protein induction.
Topics: Animals; Enzyme Inhibitors; Heat-Shock Proteins; In Vitro Techniques; Lactones; Lauraceae; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Leaves; Protein Conformation; Sesquiterpenes | 2000 |
Alcohol absorption inhibitors from bay leaf (Laurus nobilis): structure-requirements of sesquiterpenes for the activity.
Topics: 4-Butyrolactone; Absorption; Animals; Blood Glucose; Drugs, Chinese Herbal; Ethanol; Furans; Humans; Lactones; Lauraceae; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Structure; Plant Leaves; Rats; Rats, Wistar; Sesquiterpenes; Structure-Activity Relationship | 2000 |
Effects of sesquiterpenoids from "Oriental incenses" on acetic acid-induced writhing and D2 and 5-HT2A receptors in rat brain.
Topics: Acetic Acid; Analgesics; Animals; Lactones; Male; Mice; Mice, Inbred Strains; Pain; Plant Extracts; Polycyclic Sesquiterpenes; Radioligand Assay; Receptors, Opioid; Sesquiterpenes; Spiro Compounds; Tetrahydronaphthalenes | 2000 |
Patch test sensitization to Compositae mix, sesquiterpene-lactone mix, Compositae extracts, laurel leaf, Chlorophorin, Mansonone A, and dimethoxydalbergione.
Topics: Adult; Allergens; Asteraceae; Benzoquinones; Dermatitis, Allergic Contact; Female; Humans; Lactones; Male; Naphthoquinones; Patch Tests; Plant Extracts; Predictive Value of Tests; Resorcinols; Sesquiterpenes; Sesquiterpenes, Eudesmane; Stilbenes | 2001 |
Preparative isolation and purification of costunolide and dehydrocostuslactone from Aucklandia lappa Decne by high-speed counter-current chromatography.
Topics: Chromatography, High Pressure Liquid; Countercurrent Distribution; Drugs, Chinese Herbal; Lactones; Magnetic Resonance Spectroscopy; Sesquiterpenes; Spectrophotometry, Ultraviolet | 2005 |
Synergistic antimycobacterial activities of sesquiterpene lactones from Laurus spp.
Topics: Drug Synergism; Fluorometry; Lactones; Laurus; Microbial Sensitivity Tests; Mycobacterium; Plant Extracts; Sesquiterpenes | 2007 |
Effects of a hexane extract from Laurus novocanariensis leaves on the ethanol metabolism of Wistar rats.
Topics: Alcohol Dehydrogenase; Animals; Catalase; Ethanol; Gastric Emptying; Hemoglobins; Lactones; Laurus; Male; Plant Extracts; Plant Leaves; Protective Agents; Rats; Rats, Wistar; Sesquiterpenes | 2009 |
Quantitative analysis of costunolide and dehydrocostuslactone in rat plasma by ultraperformance liquid chromatography-electrospray ionization-mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Stability; Lactones; Linear Models; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization | 2011 |
Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation.
Topics: Base Sequence; Blotting, Western; Cell Line, Tumor; Chromatography, High Pressure Liquid; DNA Primers; Electrophoretic Mobility Shift Assay; Glutathione; Humans; Lactones; Phosphorylation; Polymerase Chain Reaction; Reactive Oxygen Species; Sesquiterpenes; STAT3 Transcription Factor | 2011 |
Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Lactones; Linear Models; Plant Roots; Reproducibility of Results; Saussurea; Sensitivity and Specificity; Sesquiterpenes; Solid Phase Extraction | 2011 |
[Study on stability of major pharmaceutical ingredients of vladimiriae radix before and after being roasted in artificial gastric juice, artificial intestinal juice and isolated rat gastric, intestinal or colonic incubation juice].
Topics: Animals; Asteraceae; Chromatography, High Pressure Liquid; Colon; Drug Stability; Drugs, Chinese Herbal; Gastric Juice; Gastric Mucosa; Intestinal Mucosa; Intestinal Secretions; Lactones; Male; Plants, Medicinal; Rats; Rats, Wistar; Sesquiterpenes | 2012 |
[Chemical constituents from a portion of ethanolicextract of Saussurea lappa roots].
Topics: Ethanol; Glucosides; Lactones; Plant Roots; Saussurea; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2012 |
[Chemical constituents of Dolomiaea souliei].
Topics: 4-Butyrolactone; Asteraceae; Betulinic Acid; Emodin; Lactones; Pentacyclic Triterpenes; Sesquiterpenes; Triterpenes; Ursolic Acid | 2012 |
Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Caspase 3; Caspase 7; Cell Cycle; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Lactones; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Proteolysis; Real-Time Polymerase Chain Reaction; Sarcoma; Saussurea; Sesquiterpenes; Time Factors | 2012 |
Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagenases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Gene Expression; High-Throughput Screening Assays; Humans; Lactones; Neoplasm Invasiveness; Sarcoma; Sesquiterpenes; Tumor Suppressor Protein p53 | 2013 |
Pharmacokinetic study on costunolide and dehydrocostuslactone after oral administration of traditional medicine Aucklandia lappa Decne. by LC/MS/MS.
Topics: Animals; Asteraceae; Drug Interactions; Lactones; Male; Medicine, Chinese Traditional; Molecular Structure; Rats; Rats, Wistar; Sesquiterpenes | 2014 |
Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Lactones; Male; Mice; NF-kappa B; Pleurisy; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Sesquiterpenes; STAT3 Transcription Factor; Tyrosine | 2014 |
Gastrointestinal effect of methanol extract of Radix Aucklandiae and selected active substances on the transit activity of rat isolated intestinal strips.
Topics: Animals; Asteraceae; Dose-Response Relationship, Drug; Female; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Jejunum; Lactones; Male; Methanol; Mice; Muscle Contraction; Parasympatholytics; Plant Extracts; Rats; Rats, Wistar; Rhizome; Sesquiterpenes | 2014 |
Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Feces; Lactones; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sesquiterpenes | 2014 |
Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide.
Topics: Anti-Inflammatory Agents; Apoptosis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Cells, Cultured; ErbB Receptors; Gene Expression Regulation; Glutathione; Humans; Interferon-gamma; Interleukin-22; Interleukins; Intracellular Space; Keratinocytes; Lactones; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Sesquiterpenes; STAT1 Transcription Factor; STAT3 Transcription Factor | 2014 |
Inhibition of Wnt/β-Catenin Pathway by Dehydrocostus Lactone and Costunolide in Colon Cancer Cells.
Topics: beta Catenin; Blood Proteins; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Cyclin D1; Galectin 3; Galectins; Humans; Inhibitor of Apoptosis Proteins; Lactones; Plant Roots; Saussurea; Sesquiterpenes; Survivin; Wnt Signaling Pathway | 2015 |
Alantolactone from Saussurea lappa Exerts Antiinflammatory Effects by Inhibiting Chemokine Production and STAT1 Phosphorylation in TNF-α and IFN-γ-induced in HaCaT cells.
Topics: Anti-Inflammatory Agents; Cell Line; Chemokine CCL17; Chemokine CCL22; Chemokine CCL5; Chemokines; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-8; Keratinocytes; Lactones; Phosphorylation; Plant Extracts; Polycyclic Sesquiterpenes; Saussurea; Sesquiterpenes; Sesquiterpenes, Eudesmane; STAT1 Transcription Factor; STAT5 Transcription Factor; Tumor Necrosis Factor-alpha; Tumor Suppressor Proteins | 2015 |
Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzazepines; Caspase 7; Cell Line, Tumor; Cell Movement; Drug Design; Humans; Lactones; Neoplasm Invasiveness; Neuroblastoma; Saussurea; Sesquiterpenes | 2015 |
[Pharmacokinetics study on costunolide and dehydrocostuslactone after administration of traditional Chinese medicine Weichang'an pills].
Topics: Administration, Oral; Animals; Drugs, Chinese Herbal; Lactones; Male; Rats; Rats, Wistar; Sesquiterpenes; Tablets | 2015 |
A new sesquiterpenoid from Saussurea lappa roots.
Topics: Countercurrent Distribution; Lactones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Plant Roots; Saussurea; Sesquiterpenes | 2016 |
Evaluation of protective effects of costunolide and dehydrocostuslactone on ethanol-induced gastric ulcer in mice based on multi-pathway regulation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antioxidants; Ethanol; Lactones; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Sesquiterpenes; Stomach; Stomach Ulcer; Tumor Necrosis Factor-alpha | 2016 |
"Click" reaction mediated synthesis of costunolide and dehydrocostuslactone derivatives and evaluation of their cytotoxic activity.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Lactones; Molecular Structure; Plant Roots; Plants, Medicinal; Saussurea; Sesquiterpenes | 2016 |
Costunolide and dehydrocostuslactone combination treatment inhibit breast cancer by inducing cell cycle arrest and apoptosis through c-Myc/p53 and AKT/14-3-3 pathway.
Topics: 14-3-3 Proteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclic AMP; Female; Humans; Lactones; Mice, Inbred BALB C; Mice, Nude; Oils, Volatile; Protein Interaction Maps; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Sesquiterpenes; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2017 |
Complexation of sesquiterpene lactones with cyclodextrins: synthesis and effects on their activities on parasitic weeds.
Topics: Cyclodextrins; Lactones; Models, Molecular; Plant Weeds; Santonin; Sesquiterpenes; Solubility | 2017 |
Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments.
Topics: Animals; Anti-Allergic Agents; Bronchoalveolar Lavage Fluid; Cell Degranulation; Cells, Cultured; Dose-Response Relationship, Drug; Female; Interleukin-13; Interleukin-4; Lactones; Lung; Mast Cells; Mice; Mucins; Plant Roots; Rats; Saussurea; Sesquiterpenes; Sesquiterpenes, Eudesmane | 2018 |
Pharmacokinetics of costunolide and dehydrocostuslactone after oral administration of Radix aucklandiae extract in normal and gastric ulcer rats.
Topics: Administration, Oral; Animals; Asteraceae; Lactones; Male; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Stomach Ulcer | 2018 |
Main Allelochemicals from the Rhizosphere Soil of
Topics: Antioxidants; Lactones; Rhizosphere; Saussurea; Scopoletin; Sesquiterpenes | 2018 |
Costunolide and dehydrocostuslactone from Saussurea lappa root inhibit autophagy in hepatocellular carcinoma cells.
Topics: Autophagy; Carcinoma, Hepatocellular; Humans; Lactones; Liver Neoplasms; Medicine, Kampo; Plant Roots; Saussurea; Sesquiterpenes | 2021 |
Dolomiaea souliei ethyl acetate extract protected against α-naphthylisothiocyanate-induced acute intrahepatic cholestasis through regulation of farnesoid x receptor-mediated bile acid metabolism.
Topics: 1-Naphthylisothiocyanate; Acetates; Alanine Transaminase; Animals; Asteraceae; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Cholestasis, Intrahepatic; Lactones; Male; Molecular Docking Simulation; Plant Extracts; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sesquiterpenes | 2021 |
Dynamics of germination stimulants dehydrocostus lactone and costunolide in the root exudates and extracts of sunflower.
Topics: Chromatography, Liquid; Exudates and Transudates; Germination; Helianthus; Lactones; Orobanche; Plant Extracts; Plant Roots; Sesquiterpenes; Tandem Mass Spectrometry | 2022 |