dehydroalanine has been researched along with serine in 22 studies
| Studies (dehydroalanine) | Trials (dehydroalanine) | Recent Studies (post-2010) (dehydroalanine) | Studies (serine) | Trials (serine) | Recent Studies (post-2010) (serine) |
|---|---|---|---|---|---|
| 185 | 0 | 91 | 23,914 | 115 | 6,084 |
| Protein | Taxonomy | dehydroalanine (IC50) | serine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.015 | |
| Cholinesterase | Equus caballus (horse) | 0.016 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (13.64) | 18.7374 |
| 1990's | 8 (36.36) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Brzović, PS; Dunn, MF; Ngo, K | 1 |
| Consevage, MW; Phillips, AT | 1 |
| Ando, S; Aoyagi, H; Izumiya, N; Kato, T; Waki, M | 1 |
| Langer, M; Lieber, A; Rétey, J | 1 |
| Rétey, J; Schuster, B | 1 |
| Langer, M; Reck, G; Reed, J; Rétey, J | 1 |
| Anderson, KS; Gerhardt, E; Lee, M; Liang, PH; Schlichting, I; Schneider, TR | 1 |
| Cook, PF; Kim, SK; Kredich, NM; Nalabolu, SR; Rege, VD; Schnackerz, KD; Tai, CH; Yoon, MY | 1 |
| Bettati, S; Burkhard, P; Cook, PF; Mozzarelli, A; Pucci, AM | 1 |
| Rétey, J; Schulz, GE; Schwede, TF | 1 |
| Malkoski, M; Reynolds, EC; Suckau, D; Talbo, GH | 1 |
| Murkin, AS; Tanner, ME | 1 |
| Cook, PF; Daum, S; Tai, CH | 1 |
| KOSHLAND, DE; STRUMEYER, DH; WHITE, WN | 1 |
| Fewer, DP; Jakobsen, KS; Jokela, J; Kristensen, T; Rohrlack, T; Rouhiainen, L; Sivonen, K; Tooming-Klunderud, A; Wahlsten, M | 1 |
| Chandrasekaran, S; Mishra, R; Ramapanicker, R | 1 |
| Choi, S; Jeong, J; Jung, Y; Kim, MS; Lee, E; Lee, HY; Lee, KJ; Na, S; Paek, E; Shin, DH | 1 |
| Lyons, B; Schey, KL; Truscott, RJ; Wang, Z | 1 |
| Bosma, T; de Vries, L; de Vries, MP; Kuipers, A; Moll, GN; Rink, R | 1 |
| Banerjee, S; Ekka, MK; Kaushik, A; Kumaran, S; Mittal, M; Pandya, V; Singh, AK; Singh, RP; Singh, V | 1 |
| Schey, KL; Wang, Z | 1 |
| Fernández-García, C; Foden, CS; Islam, S; Maugeri, L; Powner, MW; Sheppard, TD | 1 |
22 other study(ies) available for dehydroalanine and serine
| Article | Year |
|---|---|
Allosteric interactions coordinate catalytic activity between successive metabolic enzymes in the tryptophan synthase bienzyme complex.
Topics: Alanine; Allosteric Regulation; Catalysis; Glycerophosphates; Indoles; Kinetics; Multienzyme Complexes; Protein Conformation; Salmonella typhimurium; Serine; Spectrum Analysis; Tryptophan Synthase | 1992 |
Presence and quantity of dehydroalanine in histidine ammonia-lyase from Pseudomonas putida.
Topics: Alanine; Ammonia-Lyases; Binding Sites; Catalysis; Cyanides; Dimethyl Suberimidate; Histidine Ammonia-Lyase; Macromolecular Substances; Molecular Weight; Peptide Fragments; Pseudomonas; Serine; Structure-Activity Relationship | 1985 |
Studies of peptide antibiotics. XLIII. Syntheses of gramicidin S analogs containing D-serine or dehydroalanine in place of D-phenylalanine and asymmetric hydrogenation of the dehydroalanine residue.
Topics: Alanine; Bacteria; Gramicidin; Indicators and Reagents; Optical Rotation; Phenylalanine; Serine; Structure-Activity Relationship | 1983 |
Histidine ammonia-lyase mutant S143C is posttranslationally converted into fully active wild-type enzyme. Evidence for serine 143 to be the precursor of active site dehydroalanine.
Topics: Alanine; Base Sequence; Cysteine; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxygen; Protein Precursors; Protein Processing, Post-Translational; Pseudomonas putida; Recombinant Proteins; Serine; Structure-Activity Relationship; Sulfhydryl Compounds; Threonine | 1994 |
Serine-202 is the putative precursor of the active site dehydroalanine of phenylalanine ammonia lyase. Site-directed mutagenesis studies on the enzyme from parsley (Petroselinum crispum L.).
Topics: Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Blotting, Western; DNA; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine Ammonia-Lyase; Plants; Sequence Homology, Amino Acid; Serine | 1994 |
Identification of serine-143 as the most likely precursor of dehydroalanine in the active site of histidine ammonia-lyase. A study of the overexpressed enzyme by site-directed mutagenesis.
Topics: Alanine; Base Sequence; Binding Sites; Chromatography, Gel; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine Ammonia-Lyase; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Pseudomonas putida; Recombinant Proteins; Serine | 1994 |
Loop closure and intersubunit communication in tryptophan synthase.
Topics: Alanine; Allosteric Site; Crystallography, X-Ray; Enzyme Activation; Ligands; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Salmonella typhimurium; Serine; Structure-Activity Relationship; Tryptophan Synthase | 1998 |
Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
Topics: Alanine; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Deuterium; Enzyme Activation; Enzyme Stability; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Insertional; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1998 |
Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
Topics: Alanine; Catalysis; Crystallization; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Microspectrophotometry; Models, Chemical; Salmonella typhimurium; Serine; Sodium Azide; Structure-Activity Relationship | 1998 |
Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile.
Topics: Alanine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Energy Transfer; Histidine Ammonia-Lyase; Models, Molecular; Peptides; Protein Folding; Protein Structure, Secondary; Pseudomonas putida; Serine | 1999 |
MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide.
Topics: Alanine; Amino Acid Sequence; Anti-Bacterial Agents; Binding Sites; Caseins; Chromatography, High Pressure Liquid; Chymosin; Glycosylation; Molecular Sequence Data; Peptide Fragments; Peptides; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2001 |
Dehydroalanine-based inhibition of a peptide epimerase from spider venom.
Topics: Alanine; Amino Acid Isomerases; Amino Acid Sequence; Amino Acids; Animals; Catalysis; Hydrochloric Acid; Inhibitory Concentration 50; Molecular Mimicry; Peptides; Polyamines; Ribosomes; Serine; Spider Venoms; Spiders; Stereoisomerism; Structure-Activity Relationship | 2002 |
Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Cysteine Synthase; Deuterium; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Pyridines; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE.
Topics: Alanine; Chymotrypsin; Proteins; Research; Serine | 1963 |
Natural occurrence of microcystin synthetase deletion mutants capable of producing microcystins in strains of the genus Anabaena (Cyanobacteria).
Topics: Alanine; Anabaena; Bacterial Proteins; DNA, Bacterial; Microcystins; Molecular Sequence Data; Molecular Structure; Peptide Synthases; Phylogeny; Polymerase Chain Reaction; Protein Structure, Tertiary; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology; Serine; Water Microbiology | 2008 |
An improved procedure for the synthesis of dehydroamino acids and dehydropeptides from the carbonate derivatives of serine and threonine using tetrabutylammonium fluoride.
Topics: Alanine; Carbonates; gamma-Aminobutyric Acid; Peptides; Quaternary Ammonium Compounds; Serine; Threonine | 2010 |
Novel oxidative modifications in redox-active cysteine residues.
Topics: Alanine; Amino Acid Sequence; Animals; Catalytic Domain; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); HEK293 Cells; Humans; Mass Spectrometry; Mice; Mitochondrial Proteins; Molecular Sequence Data; Mutant Proteins; Nucleoside-Diphosphate Kinase; Oxidation-Reduction; Peptides; Peroxiredoxin VI; Protein Processing, Post-Translational; Recombinant Proteins; Serine; Sulfenic Acids; Sulfinic Acids | 2011 |
Human protein aging: modification and crosslinking through dehydroalanine and dehydrobutyrine intermediates.
Topics: Adult; Aged, 80 and over; Alanine; Amino Acid Sequence; Aminobutyrates; Cell Nucleus; Cross-Linking Reagents; Crystallins; Glutathione; Humans; Lens, Crystalline; Middle Aged; Molecular Sequence Data; Peptides; Protein Processing, Post-Translational; Serine; Tandem Mass Spectrometry; Threonine; Time Factors | 2014 |
Semi-microbiological synthesis of an active lysinoalanine-bridged analog of glucagon-like-peptide-1.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Glucagon-Like Peptide 1; Hydro-Lyases; Lactococcus lactis; Lysinoalanine; Membrane Proteins; Membrane Transport Proteins; Protein Processing, Post-Translational; SEC Translocation Channels; Serine; Substrate Specificity; Threonine | 2017 |
Substrate-Induced Facilitated Dissociation of the Competitive Inhibitor from the Active Site of O-Acetyl Serine Sulfhydrylase Reveals a Competitive-Allostery Mechanism.
Topics: Acetyl Coenzyme A; Alanine; Allosteric Regulation; Bacterial Proteins; Binding Sites; Binding, Competitive; Catalytic Domain; Crystallography, X-Ray; Cysteine Synthase; Enzyme Inhibitors; Haemophilus influenzae; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Protein Interaction Domains and Motifs; Recombinant Proteins; Salmonella enterica; Serine; Serine O-Acetyltransferase | 2017 |
Quantification of thioether-linked glutathione modifications in human lens proteins.
Topics: Adolescent; Alanine; Aminobutyrates; Cataract; Cellular Senescence; Chromatography, Liquid; Crystallins; Cysteine; Glutathione; Humans; Lens, Crystalline; Middle Aged; Protein Processing, Post-Translational; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfides; Threonine; Tissue Donors; Young Adult | 2018 |
Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water.
Topics: Alanine; Catalysis; Cysteine; Kinetics; Nitriles; Origin of Life; Peptides; Serine | 2020 |