Page last updated: 2024-09-05

deflazacort and methylprednisolone

deflazacort has been researched along with methylprednisolone in 36 studies

Compound Research Comparison

Studies
(deflazacort)
Trials
(deflazacort)
Recent Studies (post-2010)
(deflazacort)
Studies
(methylprednisolone)
Trials
(methylprednisolone)
Recent Studies (post-2010) (methylprednisolone)
4529911520,2472,6025,317

Protein Interaction Comparison

ProteinTaxonomydeflazacort (IC50)methylprednisolone (IC50)
Glucocorticoid receptorHomo sapiens (human)0.011
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.011
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.011
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.011
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.011

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's17 (47.22)18.2507
2000's9 (25.00)29.6817
2010's8 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fainstein Day, P; Ferraris, JR; Granillo, E; Gutman, R; Pasqualini, T; Ramirez, J; Ruiz, S1
Blanda, A; Catinella, M; Cigolotti, AC; Gambaro, P1
Elli, A; Mascaretti, L; Palazzi, P; Parenti, M; Quarto Di Palo, F; Rivolta, R; Zanussi, C1
Di Palo, FQ; Elli, A; Mascaretti, L; Palazzi, P; Parenti, M; Puglisi, G; Rivolta, R; Sioli, V1
Langhoff, E; Olgaard, K1
Calabria, A; Imbimbo, B; Lalumera, M; Marcolongo, R1
Di Munno, O; Imbimbo, B; Mazzantini, M; Milani, S; Occhipinti, G; Pasero, G1
Barth, J; Derendorf, H; Hochhaus, G; Möllmann, H; Rohatagi, S1
Kasperk, C; Niethard, F; Schneider, U; Sommer, U; Ziegler, R1
Bisschop, A; Bouillon, R; de Bock, V; Decramer, M; Dekhuijzen, PN; Dom, R; Gayan-Ramirez, G1
Coirini, H; De Nicola, AF; Flores, D; Gonzalez Deniselle, MC; Vega, MC1
Abelli, P; Di Palo, FQ; Elli, A; Palazzi, P; Parenti, M; Rivolta, R; Vergallo, G; Zafiropulu, S; Zanussi, C1
Carmona Martín, MM; Navarro López, V; Sáez Barcelona, JA1
Booth, R; Gorski, JP; Magnuson, SK; Porter, S1
Ferraris, JR; Jasper, H; Pasqualini, T; Pennisi, P1
Brugiatelli, M; Callea, I; Cartisano, G; Dattola, A; Irrera, G; Morabito, F; Rodinò, A1
Cabral, JP; Castanheira, A; Donato, A; Freitas, D; Saraiva, S; Sofia, C; Souto, P; Tellechea, O1
Brandi, P; Ferraris, JR; Legal, S; Oyhamburu, J; Pasqualini, T; Sorroche, P1
Cengiz, B; Kuruoğlu, R; Sucak, G; Tan, E1
Bucci, E; Carbone, R; Lo Muzio, L; Mignogna, MD; Mignogna, RE; Ruoppo, E1
Förster, B; Jeck, N; Klaus, G; Konrad, M; Soergel, M1
Buquicchio, R; Calogiuri, GF; Dagnello, M; Di Corato, R; Foti, C; Matino, MG; Ventura, MT1
Bayram, NG; Dikensoy, O; Ekinci, E; Erbagci, Z; Filiz, A; Namiduru, M1
Blasco Huelva, A; González Palomino, A; Marcos García, M; Montero García, C; Pantoja Hernández, CG; Pardo Romero, G; Pino Rivero, V; Trinidad Ruíz, G1
Blasco Huelva, A; Carrasco Claver, F; González Palomino, A; Pantoja Hernández, CG; Pardo Romero, G; Pino Rivero, V; Trinidad Ramos, G1
Alonso, G; Ferraris, JR; Galich, AM; Jasper, H; Legal, S; Pasqualini, T; Sorroche, P1
Abdi Ali, L; Bucci, M; Campostrini, L; Cavalieri, F; Cirino, G; Coppini, A; Rossini, M; Sacco, S; Saviola, G; Shams Eddin, S1
Alonso, G; Coccia, P; Ferraris, JR; Ferraris, V; Galich, A; Ghezzi, L; Guida, C; Jasper, H; Karabatas, L; Legal, S; Pasqualini, T; Sorroche, P1
Arellanes-Garcia, L; Cornejo-Ballesteros, H; Hernandez-Da Mota, SE; Melgoza-del-Angel, C; Recillas-Gispert, C; Sanchez-Gonzalez, R; Teran-Estrada, L1
Della Giustina, E; Frattini, D; Fusco, C; Pisani, F; Ucchino, V1
Alvarez-Sala-Walther, LA; Bellón-Cano, JM; de Miguel-Díez, J; Del Castillo-Rueda, A; Fernández-Herranz, J; Jiménez-García, R1
Alvarez Castro, AM; Castroagudín, JF; Molina Pérez, E; Seijo Ríos, S; Varo Pérez, E1
Álvarez-Cañas, C; Álvarez-Cuenllas, B; Jiménez, M; Jorquera, F; Linares, P; Monteserín, L; Rodríguez-Martín, L1
Fusco, C; Spagnoli, C1

Reviews

3 review(s) available for deflazacort and methylprednisolone

ArticleYear
[Systemic lupus erythematosus and pregnancy. Report of a clinical case].
    Minerva ginecologica, 1991, Volume: 43, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Chloroquine; Female; Humans; Lupus Erythematosus, Systemic; Methylprednisolone; Pregnancy; Pregnancy Complications; Pregnenediones

1991
Oral pemphigus: long term behaviour and clinical response to treatment with deflazacort in sixteen cases.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2000, Volume: 29, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Cyclophosphamide; Drug Combinations; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Mouth Diseases; Pemphigus; Pregnenediones; Remission Induction; Retrospective Studies; Treatment Outcome

2000
Acute hepatitis secondary to high-dose intravenous methylprednisolone.
    Gastroenterologia y hepatologia, 2018, Volume: 41, Issue:8

    Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Therapy, Combination; Female; Hearing Loss, Sudden; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Methylprednisolone; Middle Aged; Pregnenediones

2018

Trials

10 trial(s) available for deflazacort and methylprednisolone

ArticleYear
Immunosuppressive activity of deflazacort vs methylprednisolone in renal transplantation: effects on lymphocyte subsets.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 2

    Topics: Antigens, CD; Blood Glucose; Cadaver; Cyclosporins; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukocyte Count; Lipids; Methylprednisolone; Pregnenediones; Prospective Studies; T-Lymphocyte Subsets

1991
Deflazacort versus 6-methylprednisolone in renal transplantation: immunosuppressive activity and side effects.
    Transplantation proceedings, 1990, Volume: 22, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; Body Weight; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Pregnenediones; Random Allocation

1990
Deflazacort versus methylprednisolone in polymyalgia rheumatica: clinical equivalence and relative antiinflammatory potency of different treatment regimens.
    The Journal of rheumatology, 1995, Volume: 22, Issue:8

    Topics: Aged; Anti-Inflammatory Agents; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Methylprednisolone; Middle Aged; Polymyalgia Rheumatica; Pregnenediones; Severity of Illness Index; Time Factors; Treatment Outcome

1995
Pharmacokinetic/pharmacodynamic evaluation of deflazacort in comparison to methylprednisolone and prednisolone.
    Pharmaceutical research, 1995, Volume: 12, Issue:7

    Topics: Absorption; Administration, Oral; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Evaluation Studies as Topic; Female; Glucocorticoids; Granulocytes; Humans; Lymphocytes; Male; Methylprednisolone; Prednisolone; Pregnenediones; Prodrugs

1995
A randomized trial of deflazacort versus 6-methylprednisolone in renal transplantation--immunosuppressive activity and side effects.
    Transplantation, 1993, Volume: 55, Issue:1

    Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents; CD4-CD8 Ratio; Drug Administration Schedule; Female; Graft Rejection; Humans; Kidney Transplantation; Leukocyte Count; Lymphocytes; Male; Methylprednisolone; Pregnenediones; Prospective Studies

1993
Effects of deflazacort immunosuppression on long-term growth and growth factors after renal transplantation.
    Pediatric nephrology (Berlin, Germany), 1997, Volume: 11, Issue:3

    Topics: Adolescent; Body Height; Child; Child, Preschool; Female; Graft Survival; Growth; Growth Substances; Humans; Immunosuppressive Agents; Infant; Insulin-Like Growth Factor Binding Proteins; Kidney Transplantation; Male; Methylprednisolone; Pregnenediones; Somatomedins

1997
Effect of therapy with deflazacort on dyslipoproteinemia after pediatric renal transplantation.
    The Journal of pediatrics, 1998, Volume: 133, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; Hyperlipidemias; Kidney Transplantation; Lipoproteins; Male; Methylprednisolone; Pregnenediones

1998
Effects of deflazacort vs. methylprednisone: a randomized study in kidney transplant patients.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:5

    Topics: Adipose Tissue; Body Composition; Body Mass Index; Body Weight; Child; Cholesterol; Cholesterol, LDL; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Lipids; Methylprednisolone; Pregnenediones; Prospective Studies

2007
Compared clinical efficacy and bone metabolic effects of low-dose deflazacort and methyl prednisolone in male inflammatory arthropathies: a 12-month open randomized pilot study.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Osteoporosis; Pilot Projects; Pregnenediones; Severity of Illness Index; Treatment Outcome

2007
[Influence of systemic corticosteroid administration in the prognosis of patients with community-acquired pneumonia].
    Revista clinica espanola, 2012, Volume: 212, Issue:7

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Community-Acquired Infections; Female; Follow-Up Studies; Hospital Mortality; Humans; Length of Stay; Logistic Models; Male; Methylprednisolone; Middle Aged; Multivariate Analysis; Patient Readmission; Pneumonia; Pregnenediones; Prospective Studies; Treatment Outcome; Young Adult

2012

Other Studies

23 other study(ies) available for deflazacort and methylprednisolone

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Effect of therapy with a new glucocorticoid, deflazacort, on linear growth and growth hormone secretion after renal transplantation.
    The Journal of pediatrics, 1992, Volume: 121, Issue:5 Pt 1

    Topics: Body Height; Body Weight; Child; Child, Preschool; Female; Growth; Growth Hormone; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Pregnenediones

1992
In vitro immunosuppressive potency of deflazacort, a new bone-sparing corticosteroid on T lymphocytes, NK and K cells.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:2

    Topics: Aldosterone; Anti-Inflammatory Agents; Antibody-Dependent Cell Cytotoxicity; Humans; Hydrocortisone; Immunosuppressive Agents; Killer Cells, Natural; Lymphocyte Activation; Methylprednisolone; Pregnenediones; T-Lymphocytes

1986
In vitro and ex vivo effects of different corticosteroids on polymorphonuclear leukocyte functions.
    Advances in experimental medicine and biology, 1984, Volume: 171

    Topics: Adult; Arthritis, Rheumatoid; Betamethasone; Cells, Cultured; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Luminescent Measurements; Methylprednisolone; Middle Aged; Neutrophils; Pregnenediones; Superoxides; Zymosan

1984
Differential effects of glucocorticoids on human osteoblastic cell metabolism in vitro.
    Calcified tissue international, 1995, Volume: 57, Issue:2

    Topics: Adult; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Calcitriol; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Glucocorticoids; Humans; Kinetics; Methylprednisolone; Osteoblasts; Osteocalcin; Prednisolone; Pregnenediones; Procollagen; Time Factors

1995
Rat diaphragm contractility and histopathology are affected differently by low dose treatment with methylprednisolone and deflazacort.
    The European respiratory journal, 1995, Volume: 8, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Diaphragm; Male; Methylprednisolone; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Myosins; Pregnenediones; Random Allocation; Rats; Rats, Wistar; Time Factors

1995
Binding of the anti-inflammatory steroid deflazacort to glucocorticoid receptors in brain and peripheral tissues. In vivo and in vitro studies.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 49, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Binding, Competitive; Body Weight; Brain; Cerebral Cortex; Corticosterone; Dexamethasone; Hippocampus; In Vitro Techniques; Liver; Male; Methylprednisolone; Organ Size; Ornithine Decarboxylase; Pituitary Gland, Anterior; Prednisone; Pregnenediones; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Thymus Gland

1994
Deflazacort versus methylprednisolone in polymyalgia rheumatica.
    The Journal of rheumatology, 1996, Volume: 23, Issue:7

    Topics: Anti-Inflammatory Agents; Humans; Methylprednisolone; Polymyalgia Rheumatica; Pregnenediones

1996
Bilateral tibial marrow ablation in rats induces a rapid hypercalcemia arising from extratibial bone resorption inhibitable by methylprednisolone or deflazacort.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:2

    Topics: alpha-Macroglobulins; Animals; Bone Marrow; Bone Resorption; Calcium; Disease Models, Animal; Fracture Healing; Hydroxyproline; Hypercalcemia; Male; Methylprednisolone; Pregnenediones; Rats; Rats, Sprague-Dawley; Tibia

1997
In vitro improvement of chlorambucil-induced cytotoxicity by deflazacort and 6-methylprednisolone in B-cell chronic lymphocytic leukaemia.
    European journal of haematology, 1997, Volume: 58, Issue:5

    Topics: Analysis of Variance; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Apoptosis; Chlorambucil; Drug Interactions; Drug Synergism; Humans; Lethal Dose 50; Leukemia, Lymphocytic, Chronic, B-Cell; Methylprednisolone; Pregnenediones

1997
Oesophageal lichen planus.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:7

    Topics: Anti-Inflammatory Agents; Esophageal Diseases; Etretinate; Female; Genital Diseases, Female; Humans; Keratolytic Agents; Lichen Planus; Lichen Planus, Oral; Methylprednisolone; Middle Aged; Pregnenediones; Skin Diseases

1997
Hypereosinophilic syndrome: progression of peripheral neuropathy despite controlled eosinophil levels.
    Acta neurologica Belgica, 1999, Volume: 99, Issue:2

    Topics: Aged; Bone Marrow; Eosinophils; Fatigue; Female; Humans; Hypereosinophilic Syndrome; Immunosuppressive Agents; Leukocyte Count; Mental Disorders; Methylprednisolone; Muscle Weakness; Neural Conduction; Paraplegia; Peripheral Nervous System Diseases; Pregnenediones; Pulmonary Eosinophilia; Treatment Failure; Ventricular Dysfunction, Left

1999
Risk of steroid withdrawal in pediatric renal transplant patients with suspected steroid toxicity.
    Clinical nephrology, 2001, Volume: 56, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Child; Creatinine; Female; Glucocorticoids; Graft Rejection; Humans; Immunosuppression Therapy; Kidney; Kidney Diseases; Kidney Transplantation; Male; Methylprednisolone; Pilot Projects; Pregnenediones; Prospective Studies

2001
Alternative glucocorticoids for use in cases of adverse reaction to systemic glucocorticoids: a study on 10 patients.
    The British journal of dermatology, 2003, Volume: 148, Issue:1

    Topics: Adult; Betamethasone; Dexamethasone; Drug Eruptions; Drug Hypersensitivity; Emergencies; Female; Glucocorticoids; Humans; Hydrocortisone; Male; Methylprednisolone; Middle Aged; Pregnenediones; Skin Tests

2003
Churg-Strauss syndrome in an HCV seropositive patient.
    International journal of clinical practice, 2003, Volume: 57, Issue:5

    Topics: Adult; Albuterol; Anti-Inflammatory Agents; Blotting, Western; Churg-Strauss Syndrome; Female; Hepatitis C; Humans; Methylprednisolone; Pregnenediones; Tomography, X-Ray Computed

2003
[Statistical study and clinical results by comparison of two different protocols in the treatment of sudden hearing loss].
    Acta otorrinolaringologica espanola, 2005, Volume: 56, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Clinical Protocols; Drug Administration Schedule; Drug Therapy; Enzyme Inhibitors; Female; Hearing Loss, Sudden; Humans; Male; Methylprednisolone; Middle Aged; Nootropic Agents; Piracetam; Pregnenediones

2005
[Parotid phlegmon with involvement of both lobes. Report of a case].
    Anales otorrinolaringologicos ibero-americanos, 2006, Volume: 33, Issue:4

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Cellulitis; Ciprofloxacin; Dipyrone; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Middle Aged; Omeprazole; Parotid Diseases; Pregnenediones; Severity of Illness Index; Tomography, X-Ray Computed

2006
A study on strategies for improving growth and body composition after renal transplantation.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:4

    Topics: Body Composition; Bone Density; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Graft Rejection; Growth; Growth Disorders; Humans; Immunosuppressive Agents; Kidney Transplantation; Lumbar Vertebrae; Male; Methylprednisolone; Postoperative Complications; Pregnenediones

2010
Lupus relapse presented as frosted branch retinal angiitis: case report.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:5

    Topics: Adolescent; Azathioprine; Female; Humans; Immunosuppressive Agents; Lupus Vasculitis, Central Nervous System; Methylprednisolone; Prednisone; Pregnenediones; Recurrence; Retinal Vasculitis; Treatment Outcome

2011
Acute and chronic corticosteroid treatment of ten patients with paralytic form of Sydenham's chorea.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:4

    Topics: Adrenal Cortex Hormones; Age of Onset; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Antistreptolysin; Child; Chorea; Deglutition; Female; Humans; Male; Mastication; Methylprednisolone; Movement Disorders; Myocarditis; Neurologic Examination; Paralysis; Pregnenediones; Rheumatic Fever

2012
[Basiliximab in the treatment of acute steroid-resistant rejection after liver transplantation].
    Gastroenterologia y hepatologia, 2012, Volume: 35, Issue:9

    Topics: Acute Disease; Antibodies, Monoclonal; Basiliximab; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance; Graft Rejection; Humans; Immunosuppressive Agents; Liver Cirrhosis, Alcoholic; Liver Function Tests; Liver Neoplasms; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Pregnenediones; Receptors, Interleukin-2; Recombinant Fusion Proteins; Tacrolimus

2012
Corticosteroid treatment in Sydenham's chorea.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2018, Volume: 22, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Child; Child, Preschool; Chorea; Female; Humans; Male; Methylprednisolone; Pregnenediones

2018