Page last updated: 2024-09-05

deflazacort and cyclosporine

deflazacort has been researched along with cyclosporine in 9 studies

Compound Research Comparison

Studies (deflazacort)	Trials (deflazacort)	Recent Studies (post-2010) (deflazacort)	Studies (cyclosporine)	Trials (cyclosporine)	Recent Studies (post-2010) (cyclosporine)
452	99	115	377	2	170
452	99	115	30,547	3,802	6,558

Protein Interaction Comparison

Protein	Taxonomy	cyclosporine (IC50)
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	0.6315
Bile salt export pump	Rattus norvegicus (Norway rat)	0.6
Bile salt export pump	Homo sapiens (human)	3.5
Interleukin-2	Mus musculus (house mouse)	0.005
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	0.7
ATP-dependent translocase ABCB1	Homo sapiens (human)	1.6792
Cytochrome P450 3A4	Homo sapiens (human)	3.734
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	5.82
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A5	Homo sapiens (human)	2.06
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	4.8
Substance-K receptor	Homo sapiens (human)	4.139
Peptidyl-prolyl cis-trans isomerase B	Homo sapiens (human)	0.0088
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A7	Homo sapiens (human)	2.06
Cytochrome P450 2C19	Homo sapiens (human)	7
Multidrug resistance-associated protein 1	Homo sapiens (human)	3.5082
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Peptidyl-prolyl cis-trans isomerase A	Homo sapiens (human)	0.0252
Peptidyl-prolyl cis-trans isomerase FKBP4	Homo sapiens (human)	0.016
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens (human)	0.183
Peptidyl-prolyl cis-trans isomerase D	Homo sapiens (human)	0.0036
Sodium/bile acid cotransporter	Homo sapiens (human)	1
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.455
Cytochrome P450 3A43	Homo sapiens (human)	2.06
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Mus musculus (house mouse)	0.57
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	4.3
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	0.95

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (55.56)	18.2507
2000's	3 (33.33)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Bianchi, L; Gatti, S; Nini, G	1
Genovese, A; Marone, G; Renda, A; Stellato, C	1
Algarra, F; Almenar, L; Bretó, M; Díez, JL; Flores, A; Martí, S; Palencia, M	1
Díaz, L; Ferraris, J; Flores, D; Giogieri, S; Krmar, R; Tessler, J	1
Brandi, P; Ferraris, JR; Legal, S; Oyhamburu, J; Pasqualini, T; Sorroche, P	1
Agüero, J; Almenar Bonet, L; Martínez-Dolz, L; Moro, JA; Raso, R; Salvador, A; Sánchez-Lázaro, I	1
Hong, YS; Lee, JW; Won, NH; Yim, HE; Yoo, KH	1
Alvarez Castro, AM; Castroagudín, JF; Molina Pérez, E; Seijo Ríos, S; Varo Pérez, E	1

Trials

2 trial(s) available for deflazacort and cyclosporine

Article	Year
Effect of therapy with deflazacort on dyslipoproteinemia after pediatric renal transplantation. The Journal of pediatrics, 1998, Volume: 133, Issue:4 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; Hyperlipidemias; Kidney Transplantation; Lipoproteins; Male; Methylprednisolone; Pregnenediones	1998
Randomized prospective study of the evolution of renal function depending on the anticalcineurin used. Transplantation proceedings, 2008, Volume: 40, Issue:9 Topics: Aged; Calcineurin Inhibitors; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Heart Diseases; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Function Tests; Male; Middle Aged; Mycophenolic Acid; Pregnenediones; Tacrolimus	2008

Article

Year

Effect of therapy with deflazacort on dyslipoproteinemia after pediatric renal transplantation.

The Journal of pediatrics, 1998, Volume: 133, Issue:4

Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; Hyperlipidemias; Kidney Transplantation; Lipoproteins; Male; Methylprednisolone; Pregnenediones

1998

Randomized prospective study of the evolution of renal function depending on the anticalcineurin used.

Transplantation proceedings, 2008, Volume: 40, Issue:9

Topics: Aged; Calcineurin Inhibitors; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Heart Diseases; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Function Tests; Male; Middle Aged; Mycophenolic Acid; Pregnenediones; Tacrolimus

2008

Other Studies

7 other study(ies) available for deflazacort and cyclosporine

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Bullous pemphigoid and severe erythrodermic psoriasis: combined low-dose treatment with cyclosporine and systemic steroids. Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:2 Pt 1 Topics: Anti-Inflammatory Agents; Cyclosporine; Drug Therapy, Combination; Humans; Male; Middle Aged; Pemphigoid, Bullous; Pregnenediones; Psoriasis	1992
Anti-inflammatory effects of glucocorticoids and cyclosporin A on human basophils. European journal of clinical pharmacology, 1993, Volume: 45 Suppl 1 Topics: Anti-Inflammatory Agents; Basophils; Cyclosporine; Histamine Release; Humans; Leukotriene C4; Prednisolone; Pregnenediones	1993
[Changes in lipoprotein(a) after heart transplantation]. Revista espanola de cardiologia, 1995, Volume: 48, Issue:9 Topics: Aged; Azathioprine; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Lipoprotein(a); Male; Middle Aged; Pregnenediones; Time Factors	1995
Pharmacokinetics of deflazacort in renal transplanted and hemodialyzed children. Clinical nephrology, 1998, Volume: 50, Issue:3 Topics: Adolescent; Azathioprine; Child; Cyclosporine; Drug Therapy, Combination; Female; Half-Life; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Male; Pregnenediones; Renal Dialysis; Statistics, Nonparametric; Time Factors	1998
Churg-Strauss syndrome in a child with IgA nephropathy. Clinical nephrology, 2009, Volume: 71, Issue:3 Topics: Adrenal Cortex Hormones; Antipruritics; Child; Churg-Strauss Syndrome; Cyclosporine; Drug Therapy, Combination; Glomerulonephritis, IGA; Humans; Immunosuppressive Agents; Ketotifen; Male; Pregnenediones	2009
[Basiliximab in the treatment of acute steroid-resistant rejection after liver transplantation]. Gastroenterologia y hepatologia, 2012, Volume: 35, Issue:9 Topics: Acute Disease; Antibodies, Monoclonal; Basiliximab; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance; Graft Rejection; Humans; Immunosuppressive Agents; Liver Cirrhosis, Alcoholic; Liver Function Tests; Liver Neoplasms; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Pregnenediones; Receptors, Interleukin-2; Recombinant Fusion Proteins; Tacrolimus	2012