deferoxamine and thiazoles

deferoxamine has been researched along with thiazoles in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's7 (26.92)18.2507
2000's8 (30.77)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, E; Jacobs, A; Peter, H; Wong, A1
Cook, EP; Fragonas, JC; Hunt, NH1
Bergeron, RJ; Evans, KM; Jenny, HB; Luchetta, G; Peter, H; Streiff, RR; Vinson, JR; Wiegand, J1
Bierer, BE; Nathan, DG1
Chaudhri, G; Clark, IA1
Finger, J; Hegsted, M; Nathan, DG; Nicolosi, RJ; Peter, H; Renaud, MM; Wolfe, LC1
Baquet, A; Crichton, RR; Florence, A; Jin, Y; Schneider, YJ1
Beaudoin, RL; Gentilini, M; Guillouzo, A; Landau, I; Langlois, P; Mazier, D; Mellouk, S; Miltgen, F; Stahel, E1
Fritsch, G; Jung, A; Sawatzki, G; Spira, DT; Treumer, J1
Crichton, RR; Longueville, A1
Friedman, H; Gebran, SJ; Klein, TW; Newton, CA; Yamamoto, Y1
Bergeron, RJ; Creary, EA; Daniels, RD; King, W; Luchetta, G; Moerker, T; Peter, HH; Streiff, RR; Wiegand, J1
Bergeron, RJ; Ratliff-Thompson, K; Weimar, WR; Wiegand, J1
Ewing, MM; Philbert, MA; Tjalkens, RB1
Baker, E; Chua, AC; Kicic, A1
Dirnagl, U; Isaev, N; Karsch, M; Megow, D; Meisel, A; Prass, K; Priller, J; Ruscher, K; Scharff, A1
Drago, D; Filippi, B; Ricchelli, F; Tognon, G; Zatta, P1
Economides, C; Eracleous, E; Kolnagou, A; Kontoghiorghes, GJ1
Kontoghiorghes, GJ2
Kowdley, KV; Messner, DJ; Sivam, G1
Gaboriau, F; Lescoat, G; Mislin, GL; Rivault, F; Rodriguez-Lucena, D; Schalk, IJ1
Bonchi, C; Frangipani, E; Imperi, F; Minandri, F; Visca, P1
Du, R; Jiang, L; Li, LF; Peng, WW; Qu, DL; Wu, TT; Yang, Y; Zhao, JJ; Zhou, ZJ; Zhu, YQ1
Ferrer, P; Jacobs-Lorena, M; Sullivan, DJ; Tripathi, AK; Vega-Rodriguez, J1
Agis, H; Janjić, K; Kurzmann, C; Moritz, A; Müller, AS; Oberoi, G; Pensch, M1

Reviews

2 review(s) available for deferoxamine and thiazoles

ArticleYear
Advances in iron overload therapies. prospects for effective use of deferiprone (L1), deferoxamine, the new experimental chelators ICL670, GT56-252, L1NA11 and their combinations.
    Current medicinal chemistry, 2005, Volume: 12, Issue:23

    Topics: Benzoates; Carboxylic Acids; Deferasirox; Deferiprone; Deferoxamine; Drug Therapy, Combination; Hemochromatosis; Humans; Iron Chelating Agents; Iron Overload; Pyridones; Siderophores; Thalassemia; Thiazoles; Triazoles

2005
Future chelation monotherapy and combination therapy strategies in thalassemia and other conditions. comparison of deferiprone, deferoxamine, ICL670, GT56-252, L1NAll and starch deferoxamine polymers.
    Hemoglobin, 2006, Volume: 30, Issue:2

    Topics: Benzoates; Carboxylic Acids; Chelation Therapy; Clinical Trials as Topic; Deferasirox; Deferiprone; Deferoxamine; Drug Evaluation; Drug Therapy, Combination; Forecasting; Hemochromatosis; Humans; Hydroxyethyl Starch Derivatives; Iron Chelating Agents; Iron Overload; Molecular Structure; Pyridones; Starch; Thalassemia; Thiazoles; Transfusion Reaction; Triazoles

2006

Other Studies

24 other study(ies) available for deferoxamine and thiazoles

ArticleYear
Desferrithiocin is an effective iron chelator in vivo and in vitro but ferrithiocin is toxic.
    British journal of haematology, 1992, Volume: 81, Issue:3

    Topics: Administration, Oral; Animals; Aspartate Aminotransferases; Cells, Cultured; Deferoxamine; Dihydropyridines; Dose-Response Relationship, Drug; Injections, Subcutaneous; Iodine Radioisotopes; Iron; Iron Chelating Agents; Iron Radioisotopes; Liver; Rats; Rats, Wistar; Thiazoles; Time Factors; Transferrin; Weight Gain

1992
Interference with oxidative processes inhibits proliferation of human peripheral blood lymphocytes and murine B-lymphocytes.
    International journal of immunopharmacology, 1991, Volume: 13, Issue:7

    Topics: Animals; B-Lymphocytes; Deferoxamine; Dihydropyridines; DNA; Ferricyanides; Humans; In Vitro Techniques; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxygen; T-Lymphocytes; Thiazoles

1991
A comparative evaluation of iron clearance models.
    Annals of the New York Academy of Sciences, 1990, Volume: 612

    Topics: Animals; Bile; Chelating Agents; Deferoxamine; Dihydropyridines; Haplorhini; Hydrazines; Iron; Iron Chelating Agents; Male; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Thiazoles

1990
The effect of desferrithiocin, an oral iron chelator, on T-cell function.
    Blood, 1990, Nov-15, Volume: 76, Issue:10

    Topics: Antigens, Surface; Calcium; Cell Division; Cell Membrane; Cells, Cultured; Cytotoxicity, Immunologic; Deferoxamine; Dihydropyridines; Humans; Interleukin-2; Iron; Iron Chelating Agents; Killer Cells, Natural; Lymphocyte Activation; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Thiazoles

1990
Reactive oxygen species facilitate the in vitro and in vivo lipopolysaccharide-induced release of tumor necrosis factor.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Aug-15, Volume: 143, Issue:4

    Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Deferoxamine; Dihydropyridines; Free Radicals; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred CBA; Oxygen; Peritoneal Cavity; Thiazoles; Tumor Necrosis Factor-alpha

1989
A non-human primate model for the study of oral iron chelators.
    British journal of haematology, 1989, Volume: 72, Issue:3

    Topics: Administration, Oral; Animals; Cebus; Deferoxamine; Dihydropyridines; Disease Models, Animal; Injections, Intramuscular; Iron; Iron Chelating Agents; Thiazoles

1989
Desferrithiocin and desferrioxamine B. Cellular pharmacology and storage iron mobilization.
    Biochemical pharmacology, 1989, Oct-01, Volume: 38, Issue:19

    Topics: Animals; Cells, Cultured; Deferoxamine; Dihydropyridines; Iron; Liver; Male; Rats; Rats, Inbred Strains; Thiazoles; Tritium

1989
Iron chelators: in vitro inhibitory effect on the liver stage of rodent and human malaria.
    The American journal of tropical medicine and hygiene, 1988, Volume: 39, Issue:3

    Topics: Animals; Cells, Cultured; Deferoxamine; Dihydropyridines; Humans; Iron Chelating Agents; Liver; Malaria; Microscopy, Electron; Plasmodium falciparum; Plasmodium yoelii; Rats; Thiazoles

1988
Plasmodium falciparum: inhibition in vitro with lactoferrin, desferriferrithiocin, and desferricrocin.
    Experimental parasitology, 1987, Volume: 63, Issue:1

    Topics: Animals; Antimicrobial Cationic Peptides; Deferoxamine; Erythrocytes; Humans; Iron Chelating Agents; Lactoferrin; Lactoglobulins; Peptides; Plasmodium falciparum; Pyridines; Thiazoles

1987
An animal model of iron overload and its application to study hepatic ferritin iron mobilization by chelators.
    Biochemical pharmacology, 1986, Nov-01, Volume: 35, Issue:21

    Topics: Administration, Oral; Animals; Body Weight; Chelating Agents; Deferoxamine; Dihydropyridines; Ferritins; Ferrous Compounds; Injections, Intraperitoneal; Liver; Male; Metallocenes; Organ Size; Organometallic Compounds; Pyridines; Rats; Rats, Inbred Strains; Thiazoles

1986
A rapid colorimetric assay for evaluating Legionella pneumophila growth in macrophages in vitro.
    Journal of clinical microbiology, 1994, Volume: 32, Issue:1

    Topics: Animals; Colorimetry; Deferoxamine; Electron Transport; Female; Formazans; Iron; Legionella pneumophila; Macrophages; Mice; Mice, Inbred Strains; Tetrazolium Salts; Thiazoles

1994
A comparative study of the iron-clearing properties of desferrithiocin analogues with desferrioxamine B in a Cebus monkey model.
    Blood, 1993, Apr-15, Volume: 81, Issue:8

    Topics: Animals; Cebus; Deferoxamine; Dihydropyridines; Feces; Gastrointestinal Diseases; Iron; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Siderophores; Thiazoles

1993
The origin of the differences in (R)- and (S)-desmethyldesferrithiocin. Iron-clearing properties.
    Annals of the New York Academy of Sciences, 1998, Jun-30, Volume: 850

    Topics: Animals; Cebus; D-Amino-Acid Oxidase; Deferoxamine; Dihydropyridines; Iron; Iron Chelating Agents; Kinetics; Male; Metabolic Clearance Rate; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Thiazoles

1998
Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy.
    Brain research, 2000, Aug-25, Volume: 874, Issue:2

    Topics: Adenosine Triphosphate; Antioxidants; bcl-2-Associated X Protein; bcl-X Protein; Brain Diseases; Calcium; Deferoxamine; Dinitrobenzenes; Electrophysiology; Glioma; Humans; Mitochondria; Neuroblastoma; Oxidation-Reduction; Permeability; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles; Trifluoperazine; Tumor Cells, Cultured; Vitamin E

2000
Desferrithiocin is a more potent antineoplastic agent than desferrioxamine.
    British journal of pharmacology, 2002, Volume: 135, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Deferoxamine; Dihydropyridines; Fibroblasts; Hepatocytes; Humans; Iron; Iron Chelating Agents; Male; Mice; Rats; Rats, Wistar; Thiazoles; Tumor Cells, Cultured

2002
Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2002, Volume: 22, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Constriction; Cycloheximide; Deferoxamine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Erythropoietin; Gene Expression; Glucose; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Iron Chelating Agents; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Neurons; Nuclear Proteins; Oxygen; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Reperfusion; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors

2002
Aluminum-triggered structural modifications and aggregation of beta-amyloids.
    Cellular and molecular life sciences : CMLS, 2005, Volume: 62, Issue:15

    Topics: Aluminum; Amyloid beta-Peptides; Benzothiazoles; Chelating Agents; Circular Dichroism; Deferoxamine; Fluorescent Dyes; Hydrophobic and Hydrophilic Interactions; Liposomes; Peptide Fragments; Protein Conformation; Spectrometry, Fluorescence; Thiazoles

2005
New chelation therapies and emerging chelating drugs for the treatment of iron overload.
    Expert opinion on emerging drugs, 2006, Volume: 11, Issue:1

    Topics: beta-Thalassemia; Carboxylic Acids; Clinical Trials as Topic; Deferiprone; Deferoxamine; Drug Design; Drug Therapy, Combination; Humans; Iron Chelating Agents; Iron Overload; Pyridones; Thiazoles; Transfusion Reaction

2006
Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:1

    Topics: Animals; Cells, Cultured; Curcumin; Deferoxamine; Epithelial Cells; Ferric Compounds; Inhibitory Concentration 50; Liver; Oxidative Stress; Quaternary Ammonium Compounds; Rats; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles

2009
Synthesis and biological properties of iron chelators based on a bis-2-(2-hydroxy-phenyl)-thiazole-4-carboxamide or -thiocarboxamide (BHPTC) scaffold.
    Bioorganic & medicinal chemistry, 2010, Jan-15, Volume: 18, Issue:2

    Topics: Antineoplastic Agents; Cell Proliferation; Deferoxamine; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Iron Chelating Agents; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds; Thiazoles; Tumor Cells, Cultured

2010
Pyochelin potentiates the inhibitory activity of gallium on Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9

    Topics: Anti-Bacterial Agents; Biological Transport; Citrates; Deferoxamine; Drug Combinations; Drug Synergism; Ferrichrome; Gallium; Oligopeptides; Phenols; Pseudomonas aeruginosa; Siderophores; Sodium Citrate; Thiazoles

2014
Effects of deferoxamine on the repair ability of dental pulp cells in vitro.
    Journal of endodontics, 2014, Volume: 40, Issue:8

    Topics: Adolescent; Alkaline Phosphatase; Calcification, Physiologic; Cell Culture Techniques; Cell Differentiation; Cell Hypoxia; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Coloring Agents; Deferoxamine; Dental Pulp; Fluorescent Dyes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Odontoblasts; Osteocalcin; Regeneration; Siderophores; Tetrazolium Salts; Thiazoles; Young Adult

2014
Antimalarial iron chelator FBS0701 blocks transmission by Plasmodium falciparum gametocyte activation inhibition.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:3

    Topics: Animals; Antimalarials; Deferoxamine; Ethyl Ethers; Female; Iron Chelating Agents; Male; Plasmodium falciparum; Thiazoles

2015
Deferoxamine but Not Dimethyloxalylglycine, L-Mimosine, or Cobalt Dichloride Can Interfere with the MTT Assay.
    BioMed research international, 2018, Volume: 2018

    Topics: 3T3 Cells; Amino Acids, Dicarboxylic; Animals; Biocompatible Materials; Cell Line; Cell Survival; Cobalt; Deferoxamine; Dimethyl Sulfoxide; Mice; Mimosine; Tetrazolium Salts; Thiazoles

2018